All Relations between Alzheimer Disease and Autism Spectrum Disorder

Publication Sentence Publish Date Extraction Date Species
Marcel Pérez-Morales, Paola C Bello-Medina, Diego A González-Franco, Sofía Díaz-Cintra, Jaime García-Mena, Gustavo Pacheco-Lópe. STEERING THE MICROBIOTA-GUT-BRAIN AXIS BY ANTIBIOTICS TO MODEL NEURO-IMMUNE-ENDOCRINE DISORDERS. Neuroimmunomodulation. 2024-04-17. PMID:38631302. over the last century, animal models have been employed to study the gut-brain axis and its relationship with physiological processes, including those necessary for survival, such as food intake regulation and thermoregulation; those involved in diseases, ranging from inflammation to obesity; and those concerned to the development of neurodegenerative diseases and neuropsychiatric disorders, such as alzheimer's disease and autism spectrum disorder, respectively. 2024-04-17 2024-04-20 Not clear
Yue Li, Ruishuang Ma, Xia Ha. Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review. Cell death & disease. vol 15. issue 4. 2024-04-16. PMID:38627382. based on the latest available evidence, we provide a comprehensive overview of the mechanisms by which pten regulates activities of different stem cell populations and influences neurological disorders, encompassing autism, stroke, spinal cord injury, traumatic brain injury, alzheimer's disease and parkinson's disease. 2024-04-16 2024-04-19 Not clear
Rita Ferreira, António J Bastos-Leit. Arterial spin labelling magnetic resonance imaging and perfusion patterns in neurocognitive and other mental disorders: a systematic review. Neuroradiology. 2024-03-27. PMID:38536448. the studies were published between 2011 and 2023 and included participants with subjective cognitive decline plus; neurocognitive disorders, including mild cognitive impairment (mci), alzheimer's disease (ad), frontotemporal lobar degeneration (ftld), dementia with lewy bodies (dlb) and vascular cognitive impairment (vci); as well as schizophrenia spectrum disorders, bipolar and major depressive disorders, autism spectrum disorder, attention-deficit/hyperactivity disorder, panic disorder and alcohol use disorder. 2024-03-27 2024-03-30 human
Abdullah Al Mamun, Chuxiao Shao, Peiwu Geng, Shuanghua Wang, Jian Xia. Polyphenols Targeting NF-κB Pathway in Neurological Disorders: What We Know So Far? International journal of biological sciences. vol 20. issue 4. 2024-02-22. PMID:38385077. notably, much attention has been directed towards their potential therapeutic effects in nds such as alzheimer's disease (ad), parkinson's disease (pd), cerebral ischemia, anxiety, depression, autism, and spinal cord injury (sci). 2024-02-22 2024-02-24 Not clear
Yixiao Dong, Kunkun Zhao, Xuemei Qin, Guanhua Du, Li Ga. The mechanisms of perineuronal net abnormalities in contributing aging and neurological diseases. Ageing research reviews. 2023-10-15. PMID:37839757. pnn undergoes abnormal changes during aging and in various neurological diseases, such as alzheimer's disease, parkinson's disease, schizophrenia, autism spectrum disorder, and multiple sclerosis. 2023-10-15 2023-11-08 Not clear
Menglong Rui, Weiyu Kong, Wanting Wang, Ting Zheng, Su Wang, Wei Xi. Droj2 Facilitates Somatosensory Neurite Sculpting via GTP-Binding Protein Arf102F in International journal of molecular sciences. vol 24. issue 17. 2023-09-09. PMID:37686022. droj2 facilitates somatosensory neurite sculpting via gtp-binding protein arf102f in developmental remodeling of neurite is crucial for the accurate wiring of neural circuits in the developing nervous system in both vertebrates and invertebrates, and may also contribute to the pathogenesis of neuropsychiatric disorders, for instance, autism, alzheimer's disease (ad), and schizophrenia. 2023-09-09 2023-10-07 human
Bin Li, Xinghua Shi, Hongchang Gao, Xiaoqian Jiang, Kai Zhang, Arif O Harmanci, Bradley Mali. Enhancing Fairness in Disease Prediction with Optimizing Multiple Domain Adversarial Networks. bioRxiv : the preprint server for biology. 2023-08-23. PMID:37609241. we empirically demonstrate that the mdann approach leads to better accuracy and fairness in predicting disease progression using brain imaging data for alzheimer's disease and autism populations than state-of-the-art techniques. 2023-08-23 2023-09-07 Not clear
Hans-Gert Bernstein, Karl-Heinz Smalla, Gerburg Keilhoff, Henrik Dobrowolny, Michael R Kreutz, Johann Steine. The many "Neurofaces" of Prohibitins 1 and 2: Crucial for the Healthy Brain, Dysregulated in Numerous Brain Disorders. Journal of chemical neuroanatomy. 2023-07-31. PMID:37524128. in the healthy cns, they occur in neurons and non-neuronal cells (oligodendrocytes, astrocytes, microglia, and endothelial cells) and fulfill pivotal functions in brain development and aging, the regulation of brain metabolism, maintenance of structural integrity, synapse formation, aminoacidergic neurotransmission and, probably, regulation of brain action of certain hypothalamic-pituitary hormones.with regard to the diseased brain there is increasing evidence that prohibitins are prominently involved in numerous major diseases of the cns, which are summarized and discussed in the present review (brain tumors, neurotropic viruses, alzheimer disease, down syndrome, fronto-temporal and vascular dementia, dementia with lewy bodies, parkinson disease, huntington disease, multiple sclerosis, amyotrophic lateral sclerosis, stroke, alcohol use disorder, schizophrenia and autism). 2023-07-31 2023-08-14 Not clear
Gargi Singh, Murali Ramanatha. Repurposing Artificial Intelligence Tools for Disease Modeling: Case Study of Face Recognition Deficits in Neurodegenerative Diseases. Clinical pharmacology and therapeutics. 2023-07-02. PMID:37394678. face recognition deficits occur in diseases such as prosopagnosia, autism, alzheimer's disease, and dementias. 2023-07-02 2023-08-14 Not clear
Xiao-Jun Xiang, Sheng-Qiang Chen, Xue-Qin Zhang, Chang-Hui Chen, Shun-Yu Zhang, Hui-Ru Cai, Song-Lin Din. Possible rodent equivalent of the posterior cingulate cortex (area 23) interconnects with multimodal cortical and subcortical regions. Frontiers in neuroscience. vol 17. 2023-06-29. PMID:37383104. posterior cingulate cortex (area 23, a23) in human and monkeys is a critical component of the default mode network and is involved in many diseases such as alzheimer's disease, autism, depression, attention deficit hyperactivity disorder and schizophrenia. 2023-06-29 2023-08-14 human
Haili Li, Ze Zhang, Huixin Li, Xinyu Pan, Yue Wan. New Insights into the Roles of p53 in Central Nervous System Diseases. The international journal of neuropsychopharmacology. 2023-06-20. PMID:37338366. this review mainly discusses the latest findings regarding the role of p53 in some cns diseases, such as brain tumors, alzheimer's disease, parkinson's disease, autism, epilepsy, spinocerebellar ataxia and so on, to provide a comprehensive interpretation of the treatment of neurological diseases from a new perspective. 2023-06-20 2023-08-14 Not clear
Mengyu Pan, James M Roe, Ron Nudel, Andrew J Schork, Olena Iakunchykova, Anders M Fjell, Kristine B Walhovd, Thomas Werge, Chi-Hua Chen, Michael E Benros, Yunpeng Wan. Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study. Translational psychiatry. vol 13. issue 1. 2023-05-24. PMID:37225692. we applied two-sample mendelian randomization (mr) on the association statistics from genome-wide association studies (gwas) for circulating s100b levels measured 5-7 days after birth (the ipsych sample) and in an older adult sample (mean age, 72.5 years; the lothian sample), upon those derived from major depression disorder (mdd), schizophrenia (scz), bipolar disorder (bip), autism spectral disorder (asd), alzheimer's disease (ad), and parkinson's disease (pd). 2023-05-24 2023-08-14 Not clear
Rebecca A Piskorowski, Vivien Chevaleyr. Hippocampal area CA2: interneuron disfunction during pathological states. Frontiers in neural circuits. vol 17. 2023-05-15. PMID:37180763. in this review, we present recent studies revealing changes in inhibitory transmission and plasticity of area ca2 in mouse models of multiple sclerosis, autism spectrum disorder, alzheimer's disease, schizophrenia and the 22q11.2 deletion syndrome and propose how these changes could underly deficits in social cognition observed during these pathologies. 2023-05-15 2023-08-14 mouse
Lora E Liharska, You Jeong Park, Kimia Ziafat, Lillian Wilkins, Hannah Silk, Lisa M Linares, Ryan C Thompson, Eric Vornholt, Brendan Sullivan, Vanessa Cohen, Prashant Kota, Claudia Feng, Esther Cheng, Jessica S Johnson, Marysia-Kolbe Rieder, Jia Huang, Joseph Scarpa, Jairo Polanco, Emily Moya, Alice Hashemi, Jaroslav Bendl, Gabriel E Hoffman, Panos Roussos, Matthew A Levin, Girish N Nadkarni, Robert Sebra, John Crary, Pamela Sklar, Eric E Schadt, Noam D Beckmann, Brian H Kopell, Alexander W Charne. A study of gene expression in the living human brain. medRxiv : the preprint server for health sciences. 2023-05-10. PMID:37163086. postmortem brain gene expression signatures of alzheimer's disease, schizophrenia, parkinson's disease, bipolar disorder, and autism spectrum disorder were shown to be inaccurate representations of disease processes occurring in the living brain. 2023-05-10 2023-08-14 human
Amy R Holtby, Thomas J Hall, Beatrice A McGivney, Haige Han, Keith J Murphy, David E MacHugh, Lisa M Katz, Emmeline W Hil. Integrative genomics analysis highlights functionally relevant genes for equine behaviour. Animal genetics. 2023-03-27. PMID:36971191. the snps of high significance (q < 0.01) were in proximity to genes (coping - gabarap, ndm, oaz1, rps15a, sparcl1, vamp2; cortisol - cebpa, coa3, dusp1, hnrnph1, rack1) with biological functions in social behaviour, autism spectrum disorder, suicide, stress-induced anxiety and depression, alzheimer's disease, neurodevelopmental disorders, neuroinflammatory disease, fear-induced behaviours and alcohol and cocaine addiction. 2023-03-27 2023-08-14 cattle
Raja Chaaba, Aicha Bouaziz, Asma Ben Amor, Wissem Mnif, Mohamed Hammami, Sounira Mehr. Fatty Acid Profile and Genetic Variants of Proteins Involved in Fatty Acid Metabolism Could Be Considered as Disease Predictor. Diagnostics (Basel, Switzerland). vol 13. issue 5. 2023-03-11. PMID:36900123. fa desaturase (fads1 and fads2) polymorphisms are associated with alzheimer's disease, acute coronary syndrome, autism spectrum disorder and obesity. 2023-03-11 2023-08-14 Not clear
Raja Chaaba, Aicha Bouaziz, Asma Ben Amor, Wissem Mnif, Mohamed Hammami, Sounira Mehr. Fatty Acid Profile and Genetic Variants of Proteins Involved in Fatty Acid Metabolism Could Be Considered as Disease Predictor. Diagnostics (Basel, Switzerland). vol 13. issue 5. 2023-03-11. PMID:36900123. polymorphisms in fa elongase (elovl2) are associated with alzheimer's disease, autism spectrum disorder and obesity. 2023-03-11 2023-08-14 Not clear
Yaning Zang, Xigui Lai, Conghui Li, Dongfang Ding, Ying Wang, Yi Zh. The Role of Gut Microbiota in Various Neurological and Psychiatric Disorders-An Evidence Mapping Based on Quantified Evidence. Mediators of inflammation. vol 2023. 2023-02-23. PMID:36816743. we searched for neurological diseases and psychiatric disorders, including alzheimer's disease (ad), attention deficit hyperactivity disorder (adhd), amyotrophic lateral sclerosis (als), autism spectrum disorder (asd), anorexia nervosa (an), bipolar disorder (bd), eating disorder (ed), generalized anxiety disorder (gad), major depressive disorder (mdd), multiple sclerosis (ms), obsessive compulsive disorder (ocd), parkinson's disease (pd), posttraumatic stress disorder (ptsd), spinal cord injury (sci), schizophrenia, and stroke. 2023-02-23 2023-08-14 Not clear
Siqi Chen, Guangcai Liu, Anan Li, Zhixiang Liu, Ben Long, Xiaoquan Yang, Hui Gong, Xiangning L. Three-dimensional mapping in multi-samples with large-scale imaging and multiplexed post staining. Communications biology. vol 6. issue 1. 2023-02-03. PMID:36737476. with viral labeling, we also analyzed the input circuits of the medial prefrontal cortex in the whole brain of alzheimer's disease and autism model mice. 2023-02-03 2023-08-14 mouse
Rongguang Wang, Pratik Chaudhari, Christos Davatziko. Bias in machine learning models can be significantly mitigated by careful training: Evidence from neuroimaging studies. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 6. 2023-01-30. PMID:36716365. specifically, by using multistudy magnetic resonance imaging consortia for diagnosing alzheimer's disease, schizophrenia, and autism spectrum disorder, we find that well-trained models have a high area-under-the-curve (auc) on subjects across different subgroups pertaining to attributes such as gender, age, racial groups and different clinical studies and are unbiased under multiple fairness metrics such as demographic parity difference, equalized odds difference, equal opportunity difference, etc. 2023-01-30 2023-08-14 human