All Relations between Alzheimer Disease and Autism Spectrum Disorder

Publication Sentence Publish Date Extraction Date Species
Meenakshi Bose, Gabriela Farias Quipildor, Michelle E Ehrlich, Stephen R Salto. Intranasal Peptide Therapeutics: A Promising Avenue for Overcoming the Challenges of Traditional CNS Drug Development. Cells. vol 11. issue 22. 2022-11-26. PMID:36429060. here we review a dozen promising in peptide therapeutics in preclinical and clinical development for neurodegenerative (alzheimer's, parkinson's), neuropsychiatric (depression, ptsd, schizophrenia), and neurodevelopmental disorders (autism), with insulin, nap (davunetide), igf-1, pacap, npy, oxytocin, and glp-1 agonists prominent among them. 2022-11-26 2023-08-14 human
Aya A Ghazy, Omar A Soliman, Aya I Elbahnasi, Aya Y Alawy, Amira Ma Mansour, Mennatallah A Gowaye. Role of Oxytocin in Different Neuropsychiatric, Neurodegenerative, and Neurodevelopmental Disorders. Reviews of physiology, biochemistry and pharmacology. 2022-11-23. PMID:36416982. receptors for oxytocin are present in many areas of the brain, including the hypothalamus, amygdala, and nucleus accumbens, which have been involved in the pathophysiology of depression, anxiety, schizophrenia, autism, alzheimer's disease, parkinson's disease, and attention deficit hyperactivity disorder. 2022-11-23 2023-08-14 Not clear
Ali Jannati, Lindsay M Oberman, Alexander Rotenberg, Alvaro Pascual-Leon. Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-10-05. PMID:36198876. we then discuss the tms-eeg technique, the use of neuronavigation in tms, the neural substrate of tbs measures of plasticity, the inter- and intraindividual variability of those measures, effects of age and genetic factors on tbs aftereffects, and then summarize alterations of tms-tbs measures of plasticity in major neurological and psychiatric disorders including autism spectrum disorder, schizophrenia, depression, traumatic brain injury, alzheimer's disease, and diabetes. 2022-10-05 2023-08-14 Not clear
Xi Gu, Junhao Wang, Xiaodan Jian. miR-124- and let-7-Mediated Reprogram of Human Fibroblasts into SST Interneurons. ACS chemical neuroscience. 2022-09-08. PMID:36074953. dysfunction of γ-aminobutyric acid (gaba)ergic interneurons may cause a variety of neurological and psychiatric disorders such as epilepsy, autism, alzheimer's disease, and depression. 2022-09-08 2023-08-14 human
Bhawna, Ashwani Kumar, Meenakshi Bhatia, Archana Kapoor, Parvin Kumar, Sunil Kuma. Monoamine oxidase inhibitors: A concise review with special emphasis on structure activity relationship studies. European journal of medicinal chemistry. vol 242. 2022-08-29. PMID:36037788. excessive production of by-products of monoamine metabolism generates free radicals which cause cellular apoptosis and several neurodegenerative disorders for example alzheimer's disease, parkinson's disease, depression and autism. 2022-08-29 2023-08-14 Not clear
Katherine Dinan, Timothy G Dina. Gut Microbes and Neuropathology: Is There a Causal Nexus? Pathogens (Basel, Switzerland). vol 11. issue 7. 2022-07-27. PMID:35890040. in this narrative review, we explore the involvement of the gut microbiota in parkinson's disease, alzheimer's disease, multiple sclerosis and autism, as these are such high-prevalence disorders. 2022-07-27 2023-08-14 human
Danping Li, Qiongfang Wu, Xiaohua Ha. Application of Medial Ganglionic Eminence Cell Transplantation in Diseases Associated With Interneuron Disorders. Frontiers in cellular neuroscience. vol 16. 2022-07-22. PMID:35865112. in the current review, we describe the fate of mge cells derived into specific interneurons and the related diseases caused by interneuron loss or dysfunction and explore the potential of mge cell transplantation as a cell-based therapy for a variety of interneuron disorder-related diseases, such as epilepsy, schizophrenia, autism spectrum disorder, and alzheimer's disease. 2022-07-22 2023-08-14 Not clear
Maxsam S Donta, Yogesh Srivastava, Pierre D McCre. Delta-Catenin as a Modulator of Rho GTPases in Neurons. Frontiers in cellular neuroscience. vol 16. 2022-07-21. PMID:35860313. while links between delta-catenin and small rho gtpases have yet to be studied in many contexts, known associations include some cancers, alzheimer's disease (ad), cri-du-chat syndrome, and autism spectrum disorder (asd). 2022-07-21 2023-08-14 Not clear
Diane Seguin, Ali R Khan, Emma G Duerde. Three-Dimensional Atlas of the Human Amygdala Subnuclei Constructed Using Immunohistochemical and Ultrahigh-Field Magnetic Resonance Imaging Data. Methods in molecular biology (Clifton, N.J.). vol 2515. 2022-07-01. PMID:35776355. the amygdala is central for social and emotional processing and has been implicated in various disorders including autism spectrum disorder (asd) and alzheimer's disease (ad). 2022-07-01 2023-08-14 human
Alexander G Lucaci, Michael J Notaras, Sergei L Kosakovsky Pond, Dilek Cola. The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease? Translational psychiatry. vol 12. issue 1. 2022-06-22. PMID:35732627. bdnf has been implicated in a variety of brain disorders such as neurodevelopmental disorders (e.g., autism spectrum disorder), neuropsychiatric disorders (e.g., anxiety, depression, ptsd, and schizophrenia), and various neurodegenerative disorders (e.g., parkinson's, alzheimer's, etc.). 2022-06-22 2023-08-14 human
Dinavahi V P S Murty, Supratim Ra. Stimulus-induced Robust Narrow-band Gamma Oscillations in Human EEG Using Cartesian Gratings. Bio-protocol. vol 12. issue 7. 2022-05-09. PMID:35530517. such oscillations are modulated by higher cognitive functions, like attention, and working memory, and have been shown to be abnormal in certain neuropsychiatric disorders, such as schizophrenia, autism, and alzheimer's disease. 2022-05-09 2023-08-13 human
Illana Gozes, Shula Shazma. STOP Codon Mutations at Sites of Natural Caspase Cleavage Are Implicated in Autism and Alzheimer's Disease: The Case of ADNP. Frontiers in endocrinology. vol 13. 2022-04-11. PMID:35399934. stop codon mutations at sites of natural caspase cleavage are implicated in autism and alzheimer's disease: the case of adnp. 2022-04-11 2023-08-13 Not clear
Manish Kumar Tripathi, Maryam Kartawy, Shelly Ginzburg, Haitham Ama. Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations. Translational psychiatry. vol 12. issue 1. 2022-03-30. PMID:35351881. arsenic alters nitric oxide signaling similar to autism spectrum disorder and alzheimer's disease-associated mutations. 2022-03-30 2023-08-13 mouse
Giuseppe Donato Mangano, Antonella Riva, Antonina Fontana, Vincenzo Salpietro, Giuseppa Renata Mangano, Giulia Nobile, Alessandro Orsini, Michele Iacomino, Roberta Battini, Guja Astrea, Pasquale Striano, Rosaria Nardell. De novo GRIN2A variants associated with epilepsy and autism and literature review. Epilepsy & behavior : E&B. vol 129. 2022-02-26. PMID:35217385. among genes coding nmdar subunits, grin2b is predominantly associated with neurodevelopmental disorders such as intellectual disability, developmental delay, autism, attention-deficit/hyperactivity disorder and, further, schizophrenia, alzheimer's disease. 2022-02-26 2023-08-13 Not clear
Ewa Szczepanska-Sadowska, Agnieszka Wsol, Agnieszka Cudnoch-Jedrzejewska, Katarzyna Czarzasta, Tymoteusz Żer. Multiple Aspects of Inappropriate Action of Renin-Angiotensin, Vasopressin, and Oxytocin Systems in Neuropsychiatric and Neurodegenerative Diseases. Journal of clinical medicine. vol 11. issue 4. 2022-02-25. PMID:35207180. increasing evidence shows that the combined function of the ras, vps, and ots is altered in neuropsychiatric/neurodegenerative diseases, and in particular in patients with depression, alzheimer's disease, parkinson's disease, autism, and schizophrenia. 2022-02-25 2023-08-13 Not clear
Wei-Bin Shen, James Logue, Penghua Yang, Lauren Baracco, Montasir Elahi, E Albert Reece, Bingbing Wang, Ling Li, Thomas G Blanchard, Zhe Han, Matthew B Frieman, Robert A Rissman, Peixin Yan. SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology. bioRxiv : the preprint server for biology. 2022-02-08. PMID:35132414. here, we show that sars-cov-2 invades the brains of five patients with covid-19 and alzheimer's, autism, frontotemporal dementia or no underlying condition by infecting neurons and other cells in the cortex. 2022-02-08 2023-08-13 human
Yuvaraj Balan, Archana Gaur, Varatharajan Sakthivadivel, Bhushan Kamble, Raja Sundaramurth. Is the Gut Microbiota a Neglected Aspect of Gut and Brain Disorders? Cureus. vol 13. issue 11. 2021-12-23. PMID:34938619. in brain disorders, gut dysbiosis is involved in neuropsychiatric manifestations, including autism spectrum disorder, anxiety, and depression by interfering with neurotransmitter homeostasis, and neurodegenerative diseases, such as alzheimer's disease and parkinson's disease by releasing abnormal metabolites from the gut. 2021-12-23 2023-08-13 human
Michael Ntim, Qi-Fa Li, Yue Zhang, Xiao-Da Liu, Na Li, Hai-Lun Sun, Xuan Zhang, Bakhtawar Khan, Bin Wang, Qiong Wu, Xue-Fei Wu, Williams Walana, Khizar Khan, Quan-Hong Ma, Jie Zhao, Shao L. TRIM32 Deficiency Impairs Synaptic Plasticity by Excitatory-Inhibitory Imbalance via Notch Pathway. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32219328. trim32 has been linked to several nervous system diseases including autism spectrum disorder, depression, anxiety, and alzheimer's disease. 2021-11-29 2023-08-13 mouse
Hector Gonzalez, Richard George, Shahzad Muzaffar, Javier Acevedo, Sebastian Hoppner, Christian Mayr, Jerald Yoo, Frank Fitzek, Ibrahim Elfade. Hardware Acceleration of EEG-Based Emotion Classification Systems: A Comprehensive Survey. IEEE transactions on biomedical circuits and systems. vol 15. issue 3. 2021-11-25. PMID:34125683. recent years have witnessed a growing interest in eeg-based wearable classifiers of emotions, which could enable the real-time monitoring of patients suffering from neurological disorders such as amyotrophic lateral sclerosis (als), autism spectrum disorder (asd), or alzheimer's. 2021-11-25 2023-08-13 Not clear
Jessica Cornell, Shelbi Salinas, Hou-Yuan Huang, Miou Zho. Microglia regulation of synaptic plasticity and learning and memory. Neural regeneration research. vol 17. issue 4. 2021-11-10. PMID:34472455. these molecules released by microglia can lead to synaptic plasticity and learning and memory deficits associated with aging, alzheimer's disease, traumatic brain injury, hiv-associated neurocognitive disorder, and other neurological or mental disorders such as autism, depression and post-traumatic stress disorder. 2021-11-10 2023-08-13 Not clear