All Relations between Alzheimer Disease and Bipolar Disorder

Publication Sentence Publish Date Extraction Date Species
Zala Slabe, Rawien A Balesar, Ronald W H Verwer, Joop J Van Heerikhuize, Gwyneth A Pechler, Maja Zorović, Witte J G Hoogendijk, Dick F Swaa. Alterations in pituitary adenylate cyclase-activating polypeptide in major depressive disorder, bipolar disorder, and comorbid depression in Alzheimer's disease in the human hypothalamus and prefrontal cortex. Psychological medicine. 2023-05-25. PMID:37226771. alterations in pituitary adenylate cyclase-activating polypeptide in major depressive disorder, bipolar disorder, and comorbid depression in alzheimer's disease in the human hypothalamus and prefrontal cortex. 2023-05-25 2023-08-14 human
Mengyu Pan, James M Roe, Ron Nudel, Andrew J Schork, Olena Iakunchykova, Anders M Fjell, Kristine B Walhovd, Thomas Werge, Chi-Hua Chen, Michael E Benros, Yunpeng Wan. Circulating S100B levels at birth and risk of six major neuropsychiatric or neurological disorders: a two-sample Mendelian Randomization Study. Translational psychiatry. vol 13. issue 1. 2023-05-24. PMID:37225692. we applied two-sample mendelian randomization (mr) on the association statistics from genome-wide association studies (gwas) for circulating s100b levels measured 5-7 days after birth (the ipsych sample) and in an older adult sample (mean age, 72.5 years; the lothian sample), upon those derived from major depression disorder (mdd), schizophrenia (scz), bipolar disorder (bip), autism spectral disorder (asd), alzheimer's disease (ad), and parkinson's disease (pd). 2023-05-24 2023-08-14 Not clear
Yinrou Huang, Mengke Zhao, Xuemei Chen, Ruoyu Zhang, Anh Le, Michael Hong, Yufei Zhang, Lin Jia, Weidong Zang, Chao Jiang, Junmin Wang, Xiaochong Fan, Jian Wan. Tryptophan Metabolism in Central Nervous System Diseases: Pathophysiology and Potential Therapeutic Strategies. Aging and disease. vol 14. issue 3. 2023-05-16. PMID:37191427. in this review, we summarize the biological properties of key metabolites and their pathogenic functions in 12 disorders of the central nervous system: schizophrenia, bipolar disorder, major depressive disorder, spinal cord injury, traumatic brain injury, ischemic stroke, intracerebral hemorrhage, multiple sclerosis, alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis, and huntington's disease. 2023-05-16 2023-08-14 Not clear
Lora E Liharska, You Jeong Park, Kimia Ziafat, Lillian Wilkins, Hannah Silk, Lisa M Linares, Ryan C Thompson, Eric Vornholt, Brendan Sullivan, Vanessa Cohen, Prashant Kota, Claudia Feng, Esther Cheng, Jessica S Johnson, Marysia-Kolbe Rieder, Jia Huang, Joseph Scarpa, Jairo Polanco, Emily Moya, Alice Hashemi, Jaroslav Bendl, Gabriel E Hoffman, Panos Roussos, Matthew A Levin, Girish N Nadkarni, Robert Sebra, John Crary, Pamela Sklar, Eric E Schadt, Noam D Beckmann, Brian H Kopell, Alexander W Charne. A study of gene expression in the living human brain. medRxiv : the preprint server for health sciences. 2023-05-10. PMID:37163086. postmortem brain gene expression signatures of alzheimer's disease, schizophrenia, parkinson's disease, bipolar disorder, and autism spectrum disorder were shown to be inaccurate representations of disease processes occurring in the living brain. 2023-05-10 2023-08-14 human
Yaning Zang, Xigui Lai, Conghui Li, Dongfang Ding, Ying Wang, Yi Zh. The Role of Gut Microbiota in Various Neurological and Psychiatric Disorders-An Evidence Mapping Based on Quantified Evidence. Mediators of inflammation. vol 2023. 2023-02-23. PMID:36816743. we searched for neurological diseases and psychiatric disorders, including alzheimer's disease (ad), attention deficit hyperactivity disorder (adhd), amyotrophic lateral sclerosis (als), autism spectrum disorder (asd), anorexia nervosa (an), bipolar disorder (bd), eating disorder (ed), generalized anxiety disorder (gad), major depressive disorder (mdd), multiple sclerosis (ms), obsessive compulsive disorder (ocd), parkinson's disease (pd), posttraumatic stress disorder (ptsd), spinal cord injury (sci), schizophrenia, and stroke. 2023-02-23 2023-08-14 Not clear
Angela Maria Giada Giovenale, Giorgia Ruotolo, Amata Amy Soriano, Elisa Maria Turco, Giovannina Rotundo, Alessia Casamassa, Angela D'Anzi, Angelo Luigi Vescovi, Jessica Rosat. Deepening the understanding of CNVs on chromosome 15q11-13 by using hiPSCs: An overview. Frontiers in cell and developmental biology. vol 10. 2023-01-23. PMID:36684422. copy number variations (cnvs) of chrna7 gene have been identified in humans and are genetically linked to cognitive impairments associated with multiple disorders, including schizophrenia, bipolar disorder, epilepsy, alzheimer's disease, and others. 2023-01-23 2023-08-14 mouse
Veerta Sharma, Thakur Gurjeet Singh, Amarjot Kaur, Ashi Mannan, Sonia Dhima. Brain-Derived Neurotrophic Factor: A Novel Dynamically Regulated Therapeutic Modulator in Neurological Disorders. Neurochemical research. 2022-10-29. PMID:36308619. this article also implicates bdnf in several brain-related disorders, including alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, major depressive disorder, schizophrenia, epilepsy and bipolar disorder. 2022-10-29 2023-08-14 Not clear
Qing Tang, Xiangning Li, Jiou Wan. Tubulin deacetylase NDST3 modulates lysosomal acidification: Implications in neurological diseases. BioEssays : news and reviews in molecular, cellular and developmental biology. 2022-09-22. PMID:36135988. aberrant ndst3 expression or tubulin acetylation has been observed in an increasing number of nds, including amyotrophic lateral sclerosis and frontotemporal dementia (als/ftd), schizophrenia and bipolar disorder, alzheimer's disease (ad), and parkinson's disease (pd), suggesting that ndst3 is a key player in the pathogenesis of nds and may serve as a target for development of new treatment of nds. 2022-09-22 2023-08-14 Not clear
Taitum O Cothren, Christopher J Evonko, David A MacQuee. Olfactory Dysfunction in Schizophrenia: Evaluating Olfactory Abilities Across Species. Current topics in behavioral neurosciences. 2022-09-04. PMID:36059004. in contrast to other psychiatric conditions for which olfactory dysfunction has been observed (e.g., major depressive disorder, bipolar disorder, alzheimer's disease), the impairments observed in schizophrenia are particularly global and profound. 2022-09-04 2023-08-14 human
Ketan K Marballi, Khaled Alganem, Samuel J Brunwasser, Arhem Barkatullah, Kimberly T Meyers, Janet M Campbell, Annika B Ozols, Robert E Mccullumsmith, Amelia L Gallitan. Identification of activity-induced Egr3-dependent genes reveals genes associated with DNA damage response and schizophrenia. Translational psychiatry. vol 12. issue 1. 2022-08-08. PMID:35941129. bioinformatics and network studies have identified the immediate early gene transcription factor early growth response 3 (egr3) as a master regulator of genes differentially expressed in the brains of patients with neuropsychiatric illnesses ranging from schizophrenia and bipolar disorder to alzheimer's disease. 2022-08-08 2023-08-14 mouse
Sara Abdolahi, Ameneh Zare-Chahoki, Farshid Noorbakhsh, Ali Gorj. A Review of Molecular Interplay between Neurotrophins and miRNAs in Neuropsychological Disorders. Molecular neurobiology. 2022-08-02. PMID:35916975. emerging evidence suggests the diagnostic and therapeutic roles of the interactions between nts and mirnas in several neuropsychological disorders, including epilepsy, multiple sclerosis, alzheimer's disease, huntington's disease, amyotrophic lateral sclerosis, schizophrenia, anxiety disorders, depression, post-traumatic stress disorder, bipolar disorder, and drug abuse. 2022-08-02 2023-08-14 Not clear
Elisa Mantovani, Stefano Tamburi. D2/D3 receptor agonism: paving the way for a new therapeutic target for taste disorders in Parkinson's disease and other conditions? The international journal of neuropsychopharmacology. 2022-07-31. PMID:35908177. chemosensory (i.e., olfaction and taste) dysfunction is common in neurodegenerative (e.g., parkinson's disease, alzheimer's disease, and dementia), psychiatric (e.g., depression, bipolar disorders, other conditions), post-infectious (i.e., long covid) diseases and in the elderly. 2022-07-31 2023-08-14 human
Tai-Ling Liu, Li-Shan Fang, Jing-Ru Liou, Jia-Shan Dai, Yen-Ling Che. Determination of quetiapine and its metabolites in plasma by field-enhanced sample stacking. Journal of food and drug analysis. vol 29. issue 4. 2022-06-01. PMID:35649137. quetiapine is an atypical antipsychotic drug that can be used to treat mental disorders, including schizophrenia, bipolar disorder and alzheimer's disease. 2022-06-01 2023-08-13 Not clear
Ying-Jay Liou, Shih-Jen Tsai, Ya-Mei Bai, Tzeng-Ji Chen, Mu-Hong Che. Dementia risk in middle-aged patients with schizophrenia, bipolar disorder, and major depressive disorder: a cohort study of 84,824 subjects. European archives of psychiatry and clinical neuroscience. 2022-04-26. PMID:35469078. alzheimer disease was more likely in patients with bipolar disorder (hazard ratio [hr]: 10.37, 95% confidence interval [ci]: 6.93-15.52) and major depression (hr: 8.92, 95% ci: 5.93-13.41) than in those with schizophrenia (hr: 4.50, 95% ci: 2.84-7.13) and in controls. 2022-04-26 2023-08-13 human
Peilin Jia, Astrid M Manuel, Brisa S Fernandes, Yulin Dai, Zhongming Zha. Distinct effect of prenatal and postnatal brain expression across 20 brain disorders and anthropometric social traits: a systematic study of spatiotemporal modularity. Briefings in bioinformatics. vol 22. issue 6. 2021-12-10. PMID:34086851. specifically, we observed a strong pattern of the fetal origin for most psychiatric disorders and traits [such as schizophrenia (scz), bipolar disorder, obsessive-compulsive disorder and neuroticism], whereas increased co-expression activities of genes were more strongly associated with neurological diseases [such as alzheimer's disease (ad) and amyotrophic lateral sclerosis] and anthropometric traits (such as college completion, education and subjective well-being) in postnatal brains. 2021-12-10 2023-08-13 Not clear
Ole Kristian Drange, Olav Bjerkehagen Smeland, Alexey A Shadrin, Per Ivar Finseth, Aree Witoelar, Oleksandr Frei, Yunpeng Wang, Sahar Hassani, Srdjan Djurovic, Anders M Dale, Ole A Andreasse. Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes. Frontiers in neuroscience. vol 13. 2021-11-25. PMID:30930738. genetic overlap between alzheimer's disease and bipolar disorder implicates the mark2 and vac14 genes. 2021-11-25 2023-08-13 Not clear
Zhilei Chen, Weici Zhang, Carlo Selmi, William M Ridgway, Patrick S C Leung, Fengchun Zhang, M Eric Gershwi. The myristoylated alanine-rich C-kinase substrates (MARCKS): A membrane-anchored mediator of the cell function. Autoimmunity reviews. vol 20. issue 11. 2021-10-19. PMID:34509657. from a clinical point of view, marcks is overexpressed in patients with schizophrenia and bipolar disorders, while the brain level of marcks phosphorylation is associated with alzheimer's disease. 2021-10-19 2023-08-13 Not clear
Belén Martinez-Gualda, Dominique Schols, Steven De Jongh. A patent review of adaptor associated kinase 1 (AAK1) inhibitors (2013-present). Expert opinion on therapeutic patents. vol 31. issue 10. 2021-10-07. PMID:33971786. adaptor-associated kinase 1 (aak1) has been proposed as being a promising drug target for the treatment of a variety of neurological and psychiatric disorders, such as schizophrenia, cognitive deficits in schizophrenia, parkinson's disease, bipolar disorder, alzheimer's disease and neuropathic pain. 2021-10-07 2023-08-13 Not clear
Duttagupta Subhadeep, Bettadapura N Srikumar, Byrathnahalli S Shankaranarayana Rao, Bindu M Kutt. Short photoperiod restores ventral subicular lesion-induced deficits in affective and socio-cognitive behavior in male Wistar rats. Journal of neuroscience research. vol 98. issue 6. 2021-08-20. PMID:32118313. in summary, the study highlights the efficacy of photoperiod manipulation as a novel, non-pharmacological approach in mitigating the affective and cognitive deficits associated with neuropsychiatric disorders such as bipolar disorder and alzheimer's disease wherein circadian rhythm alterations are implicated. 2021-08-20 2023-08-13 rat
Joshua D Manduca, Rachel-Karson Thériault, Melissa L Perreaul. Glycogen synthase kinase-3: The missing link to aberrant circuit function in disorders of cognitive dysfunction? Pharmacological research. vol 157. 2021-05-31. PMID:32305493. elevated gsk-3 activity has been implicated in cognitive dysfunction associated with various disorders including alzheimer's disease, schizophrenia, type 2 diabetes, traumatic brain injury, major depressive disorder and bipolar disorder. 2021-05-31 2023-08-13 Not clear