| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Muhammad Ayaz, Osama F Mosa, Asif Nawaz, Alashary Adam Eisa Hamdoon, Modawy Elnour Modawy Elkhalifa, Abdul Sadiq, Farhat Ullah, Alshebli Ahmed, Atul Kabra, Haroon Khan, H C Ananda Murth. Neuroprotective potentials of Lead phytochemicals against Alzheimer's disease with focus on oxidative stress-mediated signaling pathways: Pharmacokinetic challenges, target specificity, clinical trials and future perspectives. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 124. 2024-01-05. PMID:38181530. |
alzheimer's diseases (ad) and dementia are among the highly prevalent neurological disorders characterized by deposition of beta amyloid (aβ) plaques, dense deposits of highly phosphorylated tau proteins, insufficiency of acetylcholine (ach) and imbalance in glutamatergic system. |
2024-01-05 |
2024-01-08 |
Not clear |
| George Anderso. A More Holistic Perspective of Alzheimer's Disease: Roles of Gut Microbiome, Adipocytes, HPA Axis, Melatonergic Pathway and Astrocyte Mitochondria in the Emergence of Autoimmunity. Frontiers in bioscience (Landmark edition). vol 28. issue 12. 2024-01-05. PMID:38179773. |
this article reviews the wider bodies of data pertaining to alzheimer's disease pathophysiology, highlighting the role of suppressed astrocyte mitochondrial function and mitochondrial melatonergic pathway as a core hub in driving neuronal loss in dementia. |
2024-01-05 |
2024-01-07 |
Not clear |
| Pallabi Sil Paul, Tark Patel, Jae-Young Cho, Allan Yarahmady, Aria Khalili, Valentyna Semenchenko, Holger Wille, Marianna Kulka, Sue-Ann Mok, Satyabrata Ka. Native PLGA nanoparticles attenuate Aβ-seed induced tau aggregation under in vitro conditions: potential implication in Alzheimer's disease pathology. Scientific reports. vol 14. issue 1. 2024-01-03. PMID:38167993. |
evidence suggests that beta-amyloid (aβ)-induced phosphorylation/aggregation of tau protein plays a critical role in the degeneration of neurons and development of alzheimer's disease (ad), the most common cause of dementia affecting the elderly population. |
2024-01-03 |
2024-01-06 |
Not clear |
| Ioanna A Angelidou, Marina Makri, Konrad Beyreuther, Mercè Boada Rovira, Akyllina Despoti, Sebastiaan Engelborghs, Andrea Miguel, Isabel Rodríguez, Hannah Stocker, Joke Temmerman, Magda Tsolaki, Görsev Yener, Deniz Yerlikaya, Birgit Teichman. Attitudes toward pre-symptomatic screening for Alzheimer's dementia in five European countries: a comparison of family members of people with Alzheimer's dementia Frontiers in genetics. vol 14. 2024-01-01. PMID:38162684. |
attitudes toward pre-symptomatic screening for alzheimer's dementia in five european countries: a comparison of family members of people with alzheimer's dementia |
2024-01-01 |
2024-01-05 |
Not clear |
| Matthew Amontree, Matthew Nelson, Lara Stefansson, Daniel Pak, Kathleen Maguire-Zeiss, R Scott Turner, Katherine Conan. Resveratrol differentially affects MMP-9 release from neurons and glia; implications for therapeutic efficacy. Journal of neurochemistry. 2024-01-01. PMID:38163875. |
resveratrol, a naturally occurring polyphenol that activates sirtuin 1 (sirt1), has been shown to reduce overall levels of matrix metalloprotease-9 (mmp-9) in cerebrospinal fluid (csf) samples from patients with alzheimer's dementia (ad). |
2024-01-01 |
2024-01-05 |
Not clear |
| Dori A Cross, Taylor I Bucy, Momotazur Rahman, John P McHug. Access to preferred skilled nursing facilities: Transitional care pathways for patients with Alzheimer's disease and related dementias. Health services research. 2023-12-25. PMID:38145955. |
the study aimed to assess whether individuals with alzheimer's disease and related dementias (adrd) experience restricted access to hospitals' high-volume preferred skilled nursing facility (snf) partners. |
2023-12-25 |
2023-12-28 |
Not clear |
| Claudio Babiloni, Giuseppe Noce, Federico Tucci, Dharmendra Jakhar, Raffaele Ferri, Simonetta Panerai, Valentina Catania, Andrea Soricelli, Marco Salvatore, Flavio Nobili, Dario Arnaldi, Francesco Famà, Carla Buttinelli, Franco Giubilei, Marco Onofrj, Fabrizio Stocchi, Laura Vacca, Fabiana Radicati, Peter Fuhr, Ute Gschwandtner, Gerhard Ransmayr, Lucilla Parnetti, Moira Marizzoni, Fabrizia D'Antonio, Giuseppe Bruno, Carlo De Lena, Bahar Güntekin, Ebru Yıldırım, Lutfu Hanoğlu, Görsev Yener, Duygu Hünerli, John-Paul Taylor, Julia Schumacher, Ian McKeith, Giovanni B Frisoni, Angelo Antonini, Florinda Ferreri, Laura Bonanni, Maria Francesca De Pandis, Claudio Del Perci. Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease. Neurobiology of aging. vol 135. 2023-12-24. PMID:38142464. |
here, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rseeg) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with parkinson's disease dementia (pdd) than in patients with alzheimer's disease dementia (add). |
2023-12-24 |
2023-12-27 |
human |
| Ram Sagar, Cristina Zivko, Ariadni Xydia, David C Weisman, Constantine G Lyketsos, Vasiliki Mahairak. Generation and Characterization of a Human-Derived and Induced Pluripotent Stem Cell (iPSC) Line from an Alzheimer's Disease Patient with Neuropsychiatric Symptoms. Biomedicines. vol 11. issue 12. 2023-12-23. PMID:38137534. |
agitation is one of the most eminent characteristics of neuropsychiatric symptoms (nps) affecting people living with alzheimer's and dementia and has serious consequences for patients and caregivers. |
2023-12-23 |
2023-12-25 |
Not clear |
| Sylvain Lehmann, Susanna Schraen-Maschke, Jean-Sébastien Vidal, Frédéric Blanc, Claire Paquet, Bernadette Allinquant, Stéphanie Bombois, Audrey Gabelle, Constance Delaby, Olivier Hano. Blood Neurofilament Levels Predict Cognitive Decline across the Alzheimer's Disease Continuum. International journal of molecular sciences. vol 24. issue 24. 2023-12-23. PMID:38139190. |
baseline plasma nfl concentration increased across the alzheimer's disease continuum with a mean nfl value of 17.1 ng/ml [sd = 6.1] in non-amnestic mci, 20.7 ng/ml [sd = 12.0] in amnestic mci, and 23.1 ng/ml [sd = 22.7] in ad dementia patients. |
2023-12-23 |
2023-12-25 |
human |
| Yeşim Olğun, Cana Aksoy Poyraz, Melda Bozluolçay, Ayşegül Gündüz, Burç Çağrı Poyra. A comparative transcranial magnetic stimulation study: Assessing cortical excitability and plasticity in Alzheimer's disease, dementia with Lewy bodies and Frontotemporal dementia. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2023-12-22. PMID:38131520. |
here, we aimed to investigate the roles of long-term potentiation-like (ltp-like) plasticity using intermittent theta burst (itbs) protocol and resting motor threshold (rmt) in the differential diagnosis of alzheimer's disease (ad), diffuse dementia with lewy bodies (dlb) and frontotemporal dementia (ftd). |
2023-12-22 |
2023-12-24 |
Not clear |
| Zhenzhu Hu, Zhaoying Li, Yu Shi, Shanyu Liu, Yuling Shen, Fangfang Hu, Qingqing Li, Xu Liu, Xinyu Gou, Zhenwei Chen, Dongdong Yan. Advancements in investigating the role of cerebral small vein loss in Alzheimer's disease-related pathological changes. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-12-22. PMID:38133856. |
alzheimer's disease (ad) is the prevailing type of dementia in the elderly, yet a comprehensive comprehension of its precise underlying mechanisms remains elusive. |
2023-12-22 |
2023-12-24 |
Not clear |
| Lucas Ronat, Alexandru Hanganu, Daphné Chylinski, Maxime Van Egroo, Justinas Narbutas, Gabriel Besson, Vincenzo Muto, Christina Schmidt, Mohamed Ali Bahri, Christophe Phillips, Eric Salmon, Pierre Maquet, Gilles Vandewalle, Fabienne Collette, Christine Basti. Prediction of cognitive decline in healthy aging based on neuropsychiatric symptoms and PET-biomarkers of Alzheimer's disease. Journal of neurology. 2023-12-20. PMID:38114820. |
neuropsychiatric symptoms (nps) have been associated with a risk of accelerated cognitive decline or conversion to dementia of the alzheimer's disease (ad) type. |
2023-12-20 |
2023-12-23 |
human |
| Yu Chen, Salvatore Spina, Patrick Callahan, Lea T Grinberg, William W Seeley, Howard J Rosen, Joel H Kramer, Bruce L Miller, Katherine P Ranki. Pathology-specific patterns of cerebellar atrophy in neurodegenerative disorders. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-12-18. PMID:38109286. |
associations of cerebellar atrophy with specific neuropathologies in alzheimer's disease and related dementias (adrd) have not been systematically analyzed. |
2023-12-18 |
2023-12-21 |
Not clear |
| Yusuke Watanabe, Yuki Miyazaki, Masahiro Hata, Ryohei Fukuma, Yasunori Aoki, Hiroaki Kazui, Toshihiko Araki, Daiki Taomoto, Yuto Satake, Takashi Suehiro, Shunsuke Sato, Hideki Kanemoto, Kenji Yoshiyama, Ryouhei Ishii, Tatsuya Harada, Haruhiko Kishima, Manabu Ikeda, Takufumi Yanagisaw. A deep learning model for the detection of various dementia and MCI pathologies based on resting-state electroencephalography data: A retrospective multicentre study. Neural networks : the official journal of the International Neural Network Society. vol 171. 2023-12-15. PMID:38101292. |
as the search for noninvasive, precise and accessible diagnostic methods continues, the efficacy of electroencephalography (eeg) combined with deep convolutional neural networks (dcnns) in varied clinical settings remains unverified, particularly for pathologies underlying mci such as alzheimer's disease (ad), dementia with lewy bodies (dlb) and idiopathic normal-pressure hydrocephalus (inph). |
2023-12-15 |
2023-12-18 |
Not clear |
| Richard Dodel, Daniela Berg, Thomas Duning, Elke Kalbe, Philipp T Meyer, Alfredo Ramirez, Alexander Storch, Dag Aarsland, Frank Jesse. [Dementia with Lewy bodies: old and new knowledge - Part 1: clinical aspects and diagnostics]. Der Nervenarzt. 2023-12-13. PMID:38092983. |
dementia with lewy bodies (dlb) is the second most common neurodegenerative dementia after alzheimer's disease. |
2023-12-13 |
2023-12-17 |
Not clear |
| Yael Hirschberg, Natalia Valle-Tamayo, Oriol Dols-Icardo, Sebastiaan Engelborghs, Bart Buelens, Roosmarijn E Vandenbroucke, Yannick Vermeiren, Kurt Boonen, Inge Merten. Proteomic comparison between non-purified cerebrospinal fluid and cerebrospinal fluid-derived extracellular vesicles from patients with Alzheimer's, Parkinson's and Lewy body dementia. Journal of extracellular vesicles. vol 12. issue 12. 2023-12-12. PMID:38082559. |
the most common neurodegenerative disorders are alzheimer's disease (ad), dementia with lewy bodies (dlb) and parkinson's disease dementia (pdd). |
2023-12-12 |
2023-12-17 |
Not clear |
| Zahra Rahemi, Juanita-Dawne R Bacsu, Justine S Sefcik, Maryam S Sadafipoor, George Demiris, Swann Arp Adam. Advance care planning and outpatient visits among older adults across cognitive levels. Aging and health research. vol 3. issue 4. 2023-12-11. PMID:38076608. |
advance care planning (acp) can help reduce end-of-life care challenges for persons with alzheimer's disease and related dementia and their care partners. |
2023-12-11 |
2023-12-17 |
human |
| Tabea M Soelter, Timothy C Howton, Amanda D Clark, Vishal H Oza, Brittany N Lasseign. Altered Glia-Neuron Communication in Alzheimer's Disease Affects WNT, p53, and NFkB Signaling Determined by snRNA-seq. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076822. |
alzheimer's disease is the most common cause of dementia and is characterized by amyloid-β plaques, tau neurofibrillary tangles, and neuronal loss. |
2023-12-11 |
2023-12-17 |
Not clear |
| Natalie C Edwards, Patrick J Lao, Mohamad J Alshikho, Olivia M Ericsson, Batool Rizvi, Melissa E Petersen, Sid O'Bryant, Lisi Flores-Aguilar, Sabrina Simoes, Mark Mapstone, Dana L Tudorascu, Shorena Janelidze, Oskar Hansson, Benjamin L Handen, Bradley T Christian, Joseph H Lee, Florence Lai, H Diana Rosas, Shahid Zaman, Ira T Lott, Michael A Yassa, José Gutierrez, Donna M Wilcock, Elizabeth Head, Adam M Brickma. Cerebrovascular disease drives Alzheimer plasma biomarker concentrations in adults with Down syndrome. medRxiv : the preprint server for health sciences. 2023-12-11. PMID:38076904. |
by age 40 years over 90% of adults with down syndrome (ds) have alzheimer's disease (ad) pathology and most progress to dementia. |
2023-12-11 |
2023-12-17 |
Not clear |
| Julie P W Bynum, Ana Montoya, Emily J Lawton, Jason B Gibbons, Mousumi Banerjee, Jennifer Meddings, Edward C Norto. Accountable Care Organization Attribution and Post-Acute Skilled Nursing Facility Outcomes for People Living With Dementia. Journal of the American Medical Directors Association. 2023-12-11. PMID:38081322. |
people with alzheimer disease and related dementias (adrd) are frequently discharged to snf for post-acute care and may be at particular risk for unintended consequences of snf cost reduction efforts. |
2023-12-11 |
2023-12-17 |
Not clear |