| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min-Kyoo Shin, Hong-Gi Kim, Seung-Hyun Baek, Woo-Ram Jung, Dong-Ik Park, Jong-Sung Park, Dong-Gyu Jo, Kil-Lyong Ki. Neuropep-1 ameliorates learning and memory deficits in an Alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques. Neurobiology of aging. vol 35. issue 5. 2014-10-06. PMID:24268884. |
neuropep-1 ameliorates learning and memory deficits in an alzheimer's disease mouse model, increases brain-derived neurotrophic factor expression in the brain, and causes reduction of amyloid beta plaques. |
2014-10-06 |
2023-08-12 |
mouse |
| Robyn A Honea, Carlos Cruchaga, Rodrigo D Perea, Andrew J Saykin, Jeffrey M Burns, Daniel R Weinberger, Alison M Goat. Characterizing the role of brain derived neurotrophic factor genetic variation in Alzheimer's disease neurodegeneration. PloS one. vol 8. issue 9. 2014-07-18. PMID:24086677. |
characterizing the role of brain derived neurotrophic factor genetic variation in alzheimer's disease neurodegeneration. |
2014-07-18 |
2023-08-12 |
human |
| Hyung Eun Lee, So Young Lee, Ju Sun Kim, Se Jin Park, Jong Min Kim, Young Woo Lee, Jun Man Jung, Dong Hyun Kim, Bum Young Shin, Dae Sik Jang, Sam Sik Kang, Jong Hoon Ry. Ethanolic Extract of the Seed of Zizyphus jujuba var. spinosa Ameliorates Cognitive Impairment Induced by Cholinergic Blockade in Mice. Biomolecules & therapeutics. vol 21. issue 4. 2013-11-18. PMID:24244815. |
also, the time-dependent expression level of brain-derived neurotrophic factor by the administration of eezs was markedly increased from 3 to 9 h. these results suggest that eezs has memory-ameliorating effect on scopolamine-induced cognitive impairment, which is mediated by the enhancement of the cholinergic neurotransmitter system, in part, via nmda receptor signaling, and that eezs would be useful agent against cognitive dysfunction such as alzheimer's disease. |
2013-11-18 |
2023-08-12 |
mouse |
| Katarzyna Adamczuk, An-Sofie De Weer, Natalie Nelissen, Kewei Chen, Kristel Sleegers, Karolien Bettens, Christine Van Broeckhoven, Mathieu Vandenbulcke, Pradeep Thiyyagura, Patrick Dupont, Koen Van Laere, Eric M Reiman, Rik Vandenbergh. Polymorphism of brain derived neurotrophic factor influences β amyloid load in cognitively intact apolipoprotein E ε4 carriers. NeuroImage. Clinical. vol 2. 2013-11-01. PMID:24179803. |
brain derived neurotrophic factor (bdnf) modulates neural plasticity, which has been implicated in alzheimer's disease. |
2013-11-01 |
2023-08-12 |
human |
| Michael P Walker, Frank M LaFerla, Salvador S Oddo, Gregory J Brewe. Reversible epigenetic histone modifications and Bdnf expression in neurons with aging and from a mouse model of Alzheimer's disease. Age (Dordrecht, Netherlands). vol 35. issue 3. 2013-10-17. PMID:22237558. |
with aging and alzheimer's disease (ad), there is an increased sensitivity to stress along with declines in the memory-associated neurotrophin brain-derived neurotrophic factor in ad. |
2013-10-17 |
2023-08-12 |
mouse |
| Chiara Boiocchi, Elisa Maggioli, Michele Zorzetto, Elena Sinforiani, Cristina Cereda, Giovanni Ricevuti, Mariaclara Cucci. Brain-derived neurotrophic factor gene variants and Alzheimer disease: an association study in an Alzheimer disease Italian population. Rejuvenation research. vol 16. issue 1. 2013-08-01. PMID:23215636. |
brain-derived neurotrophic factor gene variants and alzheimer disease: an association study in an alzheimer disease italian population. |
2013-08-01 |
2023-08-12 |
human |
| Soon-Tae Lee, Kon Chu, Keun-Hwa Jung, Jin Hee Kim, Ji-Young Huh, Hyejin Yoon, Dong-Kyu Park, Ji-Yeon Lim, Jeong-Min Kim, Daejong Jeon, Hoon Ryu, Sang Kun Lee, Manho Kim, Jae-Kyu Ro. miR-206 regulates brain-derived neurotrophic factor in Alzheimer disease model. Annals of neurology. vol 72. issue 2. 2012-11-01. PMID:22926857. |
mir-206 regulates brain-derived neurotrophic factor in alzheimer disease model. |
2012-11-01 |
2023-08-12 |
mouse |
| Shelley J Allen, Judy J Watson, David Dawbar. The neurotrophins and their role in Alzheimer's disease. Current neuropharmacology. vol 9. issue 4. 2012-08-23. PMID:22654716. |
in particular there have been a number of studies on the involvement of nerve growth factor (ngf) and brain derived neurotrophic factor (bdnf) in the development of alzheimer's disease. |
2012-08-23 |
2023-08-12 |
Not clear |
| Yuki Iwasaki, Takayuki Negishi, Makoto Inoue, Tomoko Tashiro, Takeshi Tabira, Nobuyuki Kimur. Sendai virus vector-mediated brain-derived neurotrophic factor expression ameliorates memory deficits and synaptic degeneration in a transgenic mouse model of Alzheimer's disease. Journal of neuroscience research. vol 90. issue 5. 2012-07-16. PMID:22252710. |
sendai virus vector-mediated brain-derived neurotrophic factor expression ameliorates memory deficits and synaptic degeneration in a transgenic mouse model of alzheimer's disease. |
2012-07-16 |
2023-08-12 |
mouse |
| Breno Satler Diniz, Antonio Lucio Teixeir. Brain-derived neurotrophic factor and Alzheimer's disease: physiopathology and beyond. Neuromolecular medicine. vol 13. issue 4. 2012-03-26. PMID:21898045. |
brain-derived neurotrophic factor and alzheimer's disease: physiopathology and beyond. |
2012-03-26 |
2023-08-12 |
human |
| Nela Pivac, Matea Nikolac, Gordana Nedic, Maja Mustapic, Fran Borovecki, Sanja Hajnsek, Paola Presecki, Mladen Pavlovic, Ninoslav Mimica, Dorotea Muck Sele. Brain derived neurotrophic factor Val66Met polymorphism and psychotic symptoms in Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 2. 2011-11-22. PMID:21044653. |
brain derived neurotrophic factor val66met polymorphism and psychotic symptoms in alzheimer's disease. |
2011-11-22 |
2023-08-12 |
Not clear |
| Sam-Long Hwang, Gow-Chin Ye. Effect of hesperetin against oxidative stress via ER- and TrkA-mediated actions in PC12 cells. Journal of agricultural and food chemistry. vol 59. issue 10. 2011-09-28. PMID:21486081. |
hesperetin also stimulated the activation of akt, erk, and creb as well as induced brain-derived neurotrophic factor, pparγ coactivator 1α (pgc-1α), and seladin-1 (selective alzheimer's disease indicator-1) via both er and trka in the cells. |
2011-09-28 |
2023-08-12 |
Not clear |
| Sid E O'Bryant, Valerie L Hobson, James R Hall, Robert C Barber, Song Zhang, Leigh Johnson, Ramon Diaz-Arrasti. Serum brain-derived neurotrophic factor levels are specifically associated with memory performance among Alzheimer's disease cases. Dementia and geriatric cognitive disorders. vol 31. issue 1. 2011-05-19. PMID:21135555. |
serum brain-derived neurotrophic factor levels are specifically associated with memory performance among alzheimer's disease cases. |
2011-05-19 |
2023-08-12 |
Not clear |
| Aristotle N Voineskos, Jason P Lerch, Daniel Felsky, Sajid Shaikh, Tarek K Rajji, Dielle Miranda, Nancy J Lobaugh, Benoit H Mulsant, Bruce G Pollock, James L Kenned. The brain-derived neurotrophic factor Val66Met polymorphism and prediction of neural risk for Alzheimer disease. Archives of general psychiatry. vol 68. issue 2. 2011-03-22. PMID:21300947. |
the brain-derived neurotrophic factor val66met polymorphism and prediction of neural risk for alzheimer disease. |
2011-03-22 |
2023-08-12 |
Not clear |
| Noriko Fukumoto, Takashi Fujii, Onofre Combarros, M Ilyas Kamboh, Shin-Jen Tsai, Sachio Matsushita, Benedetta Nacmias, David E Comings, Humberto Arboleda, Martin Ingelsson, Bradley T Hyman, Hiroyasu Akatsu, Andrew Grupe, Agnes Lumi Nishimura, Mayana Zatz, Kari M Mattila, Juha Rinne, Yu-ichi Goto, Takashi Asada, Shun Nakamura, Hiroshi Kunug. Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease: New data and meta-analysis. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 1. 2010-03-23. PMID:19504537. |
conflicting results have been reported as to whether genetic variations (val66met and c270t) of the brain-derived neurotrophic factor gene (bdnf) confer susceptibility to alzheimer's disease (ad). |
2010-03-23 |
2023-08-12 |
Not clear |
| Sid E O'Bryant, Valerie Hobson, James R Hall, Stephen C Waring, Wenyan Chan, Paul Massman, Laura Lacritz, C Munro Cullum, Ramon Diaz-Arrasti. Brain-derived neurotrophic factor levels in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 17. issue 2. 2009-12-16. PMID:19363274. |
brain-derived neurotrophic factor levels in alzheimer's disease. |
2009-12-16 |
2023-08-12 |
human |
| John Gunstad, Andreana Benitez, Joseph Smith, Ellen Glickman, Mary B Spitznagel, Thomas Alexander, Judi Juvancic-Heltzel, Leigh Murra. Serum brain-derived neurotrophic factor is associated with cognitive function in healthy older adults. Journal of geriatric psychiatry and neurology. vol 21. issue 3. 2009-10-20. PMID:18503034. |
these findings extend work from alzheimer disease and vascular dementia samples and indicate that higher brain-derived neurotrophic factor levels are associated with better neuropsychological function in healthy older adults. |
2009-10-20 |
2023-08-12 |
Not clear |
| Shiyong Peng, Diego J Garzon, Monica Marchese, William Klein, Stephen D Ginsberg, Beverly M Francis, Howard T J Mount, Elliott J Mufson, Ahmad Salehi, Margaret Fahnestoc. Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 29. 2009-08-10. PMID:19625522. |
decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of alzheimer's disease. |
2009-08-10 |
2023-08-12 |
mouse |
| R Hashimoto, Y Hirata, T Asada, F Yamashita, K Nemoto, T Mori, Y Moriguchi, H Kunugi, K Arima, T Ohnish. Effect of the brain-derived neurotrophic factor and the apolipoprotein E polymorphisms on disease progression in preclinical Alzheimer's disease. Genes, brain, and behavior. vol 8. issue 1. 2009-05-11. PMID:18786162. |
effect of the brain-derived neurotrophic factor and the apolipoprotein e polymorphisms on disease progression in preclinical alzheimer's disease. |
2009-05-11 |
2023-08-12 |
human |
| Zhiying Zhao, Haitao Hu, Gaifeng Fen. [Learning and memory amelioration of transplantation of the neural stem cells modified with human brain-derived neurotrophic factor gene on Alzheimer disease model rat]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. vol 19. issue 5. 2009-04-21. PMID:15960430. |
[learning and memory amelioration of transplantation of the neural stem cells modified with human brain-derived neurotrophic factor gene on alzheimer disease model rat]. |
2009-04-21 |
2023-08-12 |
human |