All Relations between Alzheimer Disease and brain derived neurotrophic factor

Publication Sentence Publish Date Extraction Date Species
Diego Garzon, Guanhua Yu, Margaret Fahnestoc. A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358753. a new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in alzheimer's disease parietal cortex. 2002-10-18 2023-08-12 human
Diego Garzon, Guanhua Yu, Margaret Fahnestoc. A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358753. previous brain-derived neurotrophic factor mrna measurements in alzheimer's disease tissue were done using the downstream coding exon present in all transcripts. 2002-10-18 2023-08-12 human
Diego Garzon, Guanhua Yu, Margaret Fahnestoc. A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358753. using rt-pcr primers specific for each upstream exon, we observe a significant decrease in three human brain-derived neurotrophic factor mrna transcripts in alzheimer's disease samples compared with controls. 2002-10-18 2023-08-12 human
N Durany, T Michel, J Kurt, F F Cruz-Sánchez, J Cervás-Navarro, P Riedere. Brain-derived neurotrophic factor and neurotrophin-3 levels in Alzheimer's disease brains. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 8. 2001-03-22. PMID:11156744. brain-derived neurotrophic factor and neurotrophin-3 levels in alzheimer's disease brains. 2001-03-22 2023-08-12 human
M G Murer, Q Yan, R Raisman-Vozar. Brain-derived neurotrophic factor in the control human brain, and in Alzheimer's disease and Parkinson's disease. Progress in neurobiology. vol 63. issue 1. 2000-12-07. PMID:11040419. brain-derived neurotrophic factor in the control human brain, and in alzheimer's disease and parkinson's disease. 2000-12-07 2023-08-12 human
C Hock, K Heese, C Hulette, C Rosenberg, U Otte. Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Archives of neurology. vol 57. issue 6. 2000-07-13. PMID:10867782. region-specific neurotrophin imbalances in alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. 2000-07-13 2023-08-12 Not clear
R M Holsinger, J Schnarr, P Henry, V T Castelo, M Fahnestoc. Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease. Brain research. Molecular brain research. vol 76. issue 2. 2000-06-05. PMID:10762711. we demonstrate a 3.4-fold decrease in brain-derived neurotrophic factor mrna levels in the parietal cortex of patients with alzheimer's disease compared to controls (p<0.004). 2000-06-05 2023-08-12 human
R M Holsinger, J Schnarr, P Henry, V T Castelo, M Fahnestoc. Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease. Brain research. Molecular brain research. vol 76. issue 2. 2000-06-05. PMID:10762711. a decrease in brain-derived neurotrophic factor synthesis could have detrimental effects on hippocampal, cortical and basal forebrain cholinergic neurons and may account for their selective vulnerability in alzheimer's disease. 2000-06-05 2023-08-12 human
V Soontornniyomkij, G Wang, C A Pittman, R L Hamilton, C A Wiley, C L Achi. Absence of brain-derived neurotrophic factor and trkB receptor immunoreactivity in glia of Alzheimer's disease. Acta neuropathologica. vol 98. issue 4. 1999-11-05. PMID:10502038. absence of brain-derived neurotrophic factor and trkb receptor immunoreactivity in glia of alzheimer's disease. 1999-11-05 2023-08-12 human
M G Murer, F Boissiere, Q Yan, S Hunot, J Villares, B Faucheux, Y Agid, E Hirsch, R Raisman-Vozar. An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease. Neuroscience. vol 88. issue 4. 1999-07-15. PMID:10336117. an immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to alzheimer's disease. 1999-07-15 2023-08-12 human
M G Murer, F Boissiere, Q Yan, S Hunot, J Villares, B Faucheux, Y Agid, E Hirsch, R Raisman-Vozar. An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease. Neuroscience. vol 88. issue 4. 1999-07-15. PMID:10336117. this fact has aroused considerable interest in the possible contribution of an abnormal brain-derived neurotrophic factor function to the aetiology and physiopathology of different neurodegenerative disorders, such as alzheimer's disease. 1999-07-15 2023-08-12 human
M G Murer, F Boissiere, Q Yan, S Hunot, J Villares, B Faucheux, Y Agid, E Hirsch, R Raisman-Vozar. An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease. Neuroscience. vol 88. issue 4. 1999-07-15. PMID:10336117. this report describes the cellular and regional distribution of brain-derived neurotrophic factor in post mortem control human brain and in limited regions of the brain in patients with alzheimer's disease, as was revealed by immunohistochemistry. 1999-07-15 2023-08-12 human
B Connor, D Young, Q Yan, R L Faull, B Synek, M Draguno. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387865. brain-derived neurotrophic factor is reduced in alzheimer's disease. 1998-02-11 2023-08-12 human
K D Murray, C M Gall, E G Jones, P J Isackso. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052419. differential regulation of brain-derived neurotrophic factor and type ii calcium/calmodulin-dependent protein kinase messenger rna expression in alzheimer's disease. 1994-09-08 2023-08-12 monkey
K D Murray, C M Gall, E G Jones, P J Isackso. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052419. the relative levels of messenger rna for brain-derived neurotrophic factor and the alpha subunit of calcium/calmodulin-dependent protein kinase type ii were examined in hippocampal sections from alzheimer's diseased and age matched non-diseased brains by in situ hybridization histochemistry. 1994-09-08 2023-08-12 monkey
K D Murray, C M Gall, E G Jones, P J Isackso. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052419. within the hippocampus of alzheimer's diseased brains, levels of calcium/calmodulin-dependent protein kinase ii messenger rna were increased and levels of brain-derived neurotrophic factor messenger rna were decreased in comparison with matched controls. 1994-09-08 2023-08-12 monkey
K D Murray, C M Gall, E G Jones, P J Isackso. Differential regulation of brain-derived neurotrophic factor and type II calcium/calmodulin-dependent protein kinase messenger RNA expression in Alzheimer's disease. Neuroscience. vol 60. issue 1. 1994-09-08. PMID:8052419. these results suggest that within the alzheimer's hippocampus an altered program of gene expression is occurring leading to aberrant levels of both calcium/calmodulin-dependent protein kinase ii and brain-derived neurotrophic factor messenger rna. 1994-09-08 2023-08-12 monkey
P A Lapchak, D M Araujo, F Heft. Systemic interleukin-1 beta decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8492907. a recent study showed that brain-derived neurotrophic factor mrna is selectively decreased in the dentate gyrus in alzheimer's disease. 1993-06-11 2023-08-12 rat
P A Lapchak, D M Araujo, F Heft. Systemic interleukin-1 beta decreases brain-derived neurotrophic factor messenger RNA expression in the rat hippocampal formation. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8492907. the reason(s) for the decrease of brain-derived neurotrophic factor mrna is not known, but one possibility may be associated with the enhanced expression of interleukin-1 in the hippocampus of alzheimer's disease patients. 1993-06-11 2023-08-12 rat