All Relations between Alzheimer Disease and microtubule-associated protein tau

Reference Sentence Publish Date Extraction Date Species
Truong Thi Vu Nu, Nhu Hoa Thi Tran, Eunjoo Nam, Tan Tai Nguyen, Won Jung Yoon, Sungbo Cho, Jungsuk Kim, Keun-A Chang, Heongkyu J. Blood-based immunoassay of tau proteins for early diagnosis of Alzheimer's disease using surface plasmon resonance fiber sensors. RSC advances vol 8 issue 14 2022 35539129 blood-based immunoassay of tau proteins for early diagnosis of alzheimer's disease using surface plasmon resonance fiber sensors. 2022-05-11 2022-05-12 Not clear
Hrushikesh Dixit, C Selvaa Kumar, Debjani Dasgupta, Nikhil Gadewa. Molecular docking analysis of hyperphosphorylated tau protein with compounds derived from Bacopa monnieri and Withania somnifera. Bioinformation vol 17 issue 9 2022 35539884 tau protein, the major player in alzheimer's disease forms neurofibrillary tangles in elderly people. 2022-05-11 2022-05-12 Not clear
Hrushikesh Dixit, C Selvaa Kumar, Debjani Dasgupta, Nikhil Gadewa. Molecular docking analysis of hyperphosphorylated tau protein with compounds derived from Bacopa monnieri and Withania somnifera. Bioinformation vol 17 issue 9 2022 35539884 we show that compounds such as bacopaside ii, bacopaside xii, and nicotine showed optimal binding features with the r2 repeat domain of hyperphosphorylated tau protein for further consideration in the context of alzheimer's disease (ad). 2022-05-11 2022-05-12 Not clear
S Gauthier, A Boxer, D Knopman, J Sims, R Doody, P Aisen, T Iwatsubo, R Bateman, B Vella. Therapeutic Targets for Alzheimer's Disease: Amyloid Vs. Non-Amyloid. Where Does Consensus Lie Today? An CTAD Task Force Report. The journal of prevention of Alzheimer's disease vol 9 issue 2 2022 35542994 there was consensus that both amyloid and tau pathologies should be targeted in alzheimer's disease, as well as additional pathophysiological mechanisms such as neuroinflammation. 2022-05-11 2022-05-12 Not clear
Yuan Cheng, Jun-Rong Ren, Jie-Ming Jian, Chen-Yang He, Man-Yu Xu, Gui-Hua Zeng, Cheng-Rong Tan, Ying-Ying Shen, Wang-Sheng Jin, Dong-Wan Chen, Hui-Yun Li, Xu Yi, Yuan Zhang, Xian-Le Bu, Yan-Jiang Wan. Associations of plasma angiostatin and amyloid-\\xce\\xb2 and tau levels in Alzheimer's disease. Translational psychiatry vol 12 issue 1 2022 35538065 associations of plasma angiostatin and amyloid-\xce\xb2 and tau levels in alzheimer's disease. 2022-05-10 2022-05-12 Not clear
Cinzia Maschio, Ruiqing N. Amyloid and Tau Positron Emission Tomography Imaging in Alzheimer's Disease and Other Tauopathies. Frontiers in aging neuroscience vol 14 issue 2022 35527737 amyloid and tau positron emission tomography imaging in alzheimer's disease and other tauopathies. 2022-05-09 2022-05-12 Not clear
Peng Zeng, Hong-Fei Su, Chao-Yuan Ye, Shuo-Wen Qiu, Anbing Shi, Jian-Zhi Wang, Xin-Wen Zhou, Qing Tia. A Tau Pathogenesis-Based Network Pharmacology Approach for Exploring the Protections of Frontiers in pharmacology vol 13 issue 2022 35529440 a tau pathogenesis-based network pharmacology approach for exploring the protections of alzheimer's disease (ad) is the most common cause of neurodegenerative dementia and one of the top medical concerns worldwide. 2022-05-09 2022-05-12 Not clear
Dongmei Chen, Guihua Lan, Ruomeng Li, Yingxue Mei, Xindong Shui, Xi Gu, Long Wang, Tao Zhang, Chen-Ling Gan, Yongfang Xia, Li Hu, Yuan Tian, Mi Zhang, Tae Ho Le. Melatonin ameliorates tau-related pathology via the miR-504-3p and CDK5 axis in Alzheimer's disease. Translational neurodegeneration vol 11 issue 1 2022 35527277 intracellular accumulation of the microtubule-associated protein tau and its hyperphosphorylated forms is a key neuropathological feature of alzheimer's disease (ad). 2022-05-08 2022-05-12 Not clear
Gurpreet Singh, Peng Liu, Katherine R Yao, Jessica M Strasser, Chris Hlynialuk, Kailee Leinonen-Wright, Peter J Teravskis, Jessica M Choquette, Junaid Ikramuddin, Merlin Bresinsky, Kathryn M Nelson, Dezhi Liao, Karen H Ashe, Michael A Walters, Steffen Pocke. Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy. ACS chemical neuroscience vol issue 2022 35522720 synaptic and cognitive deficits mediated by a severe reduction in excitatory neurotransmission caused by a disproportionate accumulation of the neuronal protein tau in dendritic spines is a fundamental mechanism that has been found repeatedly in models of tauopathies, including alzheimer's disease, lewy body dementia, frontotemporal dementia, and traumatic brain injury. 2022-05-06 2022-05-09 Not clear
Abha Dangi, Abhishek Ankur Balmik, Archana Kisan Ghorpade, Nalini Vijay Gorantla, Shweta Kishor Sonawane, Subashchandrabose Chinnathambi, Udaya Kiran Marell. Residue-based propensity of aggregation in the Tau amyloidogenic hexapeptides AcPHF6* and AcPHF6. RSC advances vol 10 issue 46 2022 35516938 in alzheimer's disease and related tauopathies, the aggregation of microtubule-associated protein, tau, into fibrils occurs 2022-05-06 2022-05-07 Not clear
Amy R Nelso. Peripheral Pathways to Neurovascular Unit Dysfunction, Cognitive Impairment, and Alzheimer's Disease. Frontiers in aging neuroscience vol 14 issue 2022 35517047 although there are nuances and details continuously being unraveled, many key players were identified in the early 1900's by dr. oskar fischer and dr. alois alzheimer, including amyloid-beta (a\xce\xb2), tau, vascular abnormalities, gliosis, and a possible role of infections. 2022-05-06 2022-05-07 Not clear
Patricia Yuste-Checa, Andreas Bracher, F Ulrich Hart. The chaperone Clusterin in neurodegeneration-friend or foe? BioEssays : news and reviews in molecular, cellular and developmental biology vol issue 2022 35521968 aggregates of the microtubule-associated protein tau are observed in alzheimer's disease and primary tauopathies. 2022-05-06 2022-05-07 Not clear
Patricia Yuste-Checa, Andreas Bracher, F Ulrich Hart. The chaperone Clusterin in neurodegeneration-friend or foe? BioEssays : news and reviews in molecular, cellular and developmental biology vol issue 2022 35521968 these findings raise the possibility of a mechanistic link between clusterin upregulation observed in alzheimer's disease and the progression of tau pathology. 2022-05-06 2022-05-07 Not clear
Charles Windon, Leonardo Iaccarino, Nidhi Mundada, Isabel Allen, Adam L Boxer, Desiree Byrd, Monica Rivera-Mindt, Gil D Rabinovic. Comparison of plasma and CSF biomarkers across ethnoracial groups in the ADNI. Alzheimer's & dementia (Amsterdam, Netherlands) vol 14 issue 1 2022 35510092 ethnoracial differences in cerebrospinal fluid (csf; amyloid beta 42 [a\xce\xb242], total tau [t-tau], phosphorylated tau 181 [p-tau181], and plasma (p-tau181, neurofilament light [nfl]) biomarkers of alzheimer's disease (ad) are incompletely understood. 2022-05-05 2022-05-07 Not clear
O G Steele, A C Stuart, L Minkley, K Shaw, O Bonnar, S Anderle, A C Penn, J Rusted, L Serpell, C Hall, S Kin. A multi-hit hypothesis for an APOE4-dependent pathophysiological state. The European journal of neuroscience vol issue 2022 35510513 intriguingly, apoe4 has been associated with neuropathological and cognitive deficits in the absence of alzheimer's disease-related amyloid or tau pathology. 2022-05-05 2022-05-07 Not clear
Swadesh Pal, Roderick Melni. Nonlocal models in the analysis of brain neurodegenerative protein dynamics with application to Alzheimer's disease. Scientific reports vol 12 issue 1 2022 35513401 in this paper, we focus on alzheimer's disease, where it is believed that the concentration changes in amyloid-beta and tau proteins play a central role in its onset and development. 2022-05-05 2022-05-07 Not clear
Marangelie Criado-Marrero, Danielle M Blazier, Lauren A Gould, Niat T Gebru, Santiago Rodriguez Ospina, Debra S Armendariz, April L Darling, David Beaulieu-Abdelahad, Laura J Blai. Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice. Scientific reports vol 12 issue 1 2022 35513476 tau accumulation and progressive loss of neurons are associated with alzheimer's disease (ad). 2022-05-05 2022-05-07 Not clear
Ian Fyf. Influence of amyloid-\\xce\\xb2 on tau spread in Alzheimer disease explained. Nature reviews. Neurology vol issue 2022 35508634 influence of amyloid-\xce\xb2 on tau spread in alzheimer disease explained. 2022-05-04 2022-05-07 Not clear
Panos Theofilas, Antonia M H Piergies, Ian Oh, Yoo Bin Lee, Song Hua Li, Felipe L Pereira, Cathrine Petersen, Alexander J Ehrenberg, Rana A Eser, Andrew J Ambrose, Brian Chin, Teddy Yang, Shireen Khan, Raymond Ng, Salvatore Spina, Willian W Seeley, Bruce L Miller, Michelle R Arkin, Lea T Grinber. Caspase-6-cleaved tau is relevant in Alzheimer's disease and marginal in four-repeat tauopathies: diagnostic and therapeutic implications. Neuropathology and applied neurobiology vol issue 2022 35508761 caspase-6-cleaved tau is relevant in alzheimer's disease and marginal in four-repeat tauopathies: diagnostic and therapeutic implications. 2022-05-04 2022-05-07 Not clear
Panos Theofilas, Antonia M H Piergies, Ian Oh, Yoo Bin Lee, Song Hua Li, Felipe L Pereira, Cathrine Petersen, Alexander J Ehrenberg, Rana A Eser, Andrew J Ambrose, Brian Chin, Teddy Yang, Shireen Khan, Raymond Ng, Salvatore Spina, Willian W Seeley, Bruce L Miller, Michelle R Arkin, Lea T Grinber. Caspase-6-cleaved tau is relevant in Alzheimer's disease and marginal in four-repeat tauopathies: diagnostic and therapeutic implications. Neuropathology and applied neurobiology vol issue 2022 35508761 yet, the relationship between acasp-6, different forms of tr-tau, and hyperphosphorylated tau (p-tau) accumulation in human brains with alzheimer's disease (ad) and other tauopathies remains unclear. 2022-05-04 2022-05-07 Not clear
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