| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Johanna Giovannini, Willy Smeralda, Marie Jouanne, Jana Sopkova-de Oliveira Santos, Marco Catto, Anne Sophie Voisin-Chire. Tau protein aggregation: key features to improve drug discovery screening. Drug discovery today. 2022-01-27. PMID:35085785. |
tau pathologies include a broad spectrum of diseases, with alzheimer's disease (ad) being the most common tauopathy. |
2022-01-27 |
2023-08-13 |
Not clear |
| Heping Zhang, Fan Lu, Panhong Liu, Zhaohui Qiu, Jianling Li, Xiaotong Wang, Hui Xu, Yandong Zhao, Xuemin Li, Huadong Wang, Daxiang Lu, Renbin Q. A direct interaction between RhoGDIα/Tau alleviates hyperphosphorylation of Tau in Alzheimer's disease and vascular dementia. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2022-01-26. PMID:35080740. |
a direct interaction between rhogdiα/tau alleviates hyperphosphorylation of tau in alzheimer's disease and vascular dementia. |
2022-01-26 |
2023-08-13 |
Not clear |
| Maria Eduarda Schneider, Lucía Guillade, Miguel A Correa-Duarte, Felismina T C Moreir. Development of a biosensor for phosphorylated Tau 181 protein detection in Early-Stage Alzheimer's disease. Bioelectrochemistry (Amsterdam, Netherlands). vol 145. 2022-01-25. PMID:35078121. |
development of a biosensor for phosphorylated tau 181 protein detection in early-stage alzheimer's disease. |
2022-01-25 |
2023-08-13 |
Not clear |
| Justine D Manos, Christina N Preiss, Nandini Venkat, Joseph Tamm, Peter Reinhardt, Taekyung Kwon, Jessica Wu, Allison D Winter, Thomas R Jahn, Kiran Yanamandra, Katherine Titterton, Eric Karran, Xavier Langloi. Uncovering specificity of endogenous TAU aggregation in a human iPSC-neuron TAU seeding model. iScience. vol 25. issue 1. 2022-01-24. PMID:35072001. |
tau pathobiology has emerged as a key component underlying alzheimer's disease (ad) progression; however, human neuronal |
2022-01-24 |
2023-08-13 |
human |
| Anna Bergauer, Robin van Osch, Silke van Elferen, Sofia Gyllvik, Hrishikesh Venkatesh, Rudy Schreibe. The diagnostic potential of fluid and imaging biomarkers in chronic traumatic encephalopathy (CTE). Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 146. 2022-01-22. PMID:35062068. |
future research could incorporate machine learning methodologies to differentiate between the tau accumulation patterns detected by pet/fmri in alzheimer's and cte patients. |
2022-01-22 |
2023-08-13 |
Not clear |
| Tara E Tracy, Jesus Madero-Pérez, Danielle L Swaney, Timothy S Chang, Michelle Moritz, Csaba Konrad, Michael E Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q Trojanowski, Virginia M Y Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J Krogan, Daniel H Geschwind, Li Ga. Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration. Cell. 2022-01-22. PMID:35063084. |
tau (mapt) drives neuronal dysfunction in alzheimer disease (ad) and other tauopathies. |
2022-01-22 |
2023-08-13 |
human |
| Ryszard Pluta, Jacek Kiś, Sławomir Januszewski, Mirosław Jabłoński, Stanisław J Czuczwa. Cross-Talk between Amyloid, Tau Protein and Free Radicals in Post-Ischemic Brain Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy. Antioxidants (Basel, Switzerland). vol 11. issue 1. 2022-01-21. PMID:35052650. |
cross-talk between amyloid, tau protein and free radicals in post-ischemic brain neurodegeneration in the form of alzheimer's disease proteinopathy. |
2022-01-21 |
2023-08-13 |
Not clear |
| Ryszard Pluta, Jacek Kiś, Sławomir Januszewski, Mirosław Jabłoński, Stanisław J Czuczwa. Cross-Talk between Amyloid, Tau Protein and Free Radicals in Post-Ischemic Brain Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy. Antioxidants (Basel, Switzerland). vol 11. issue 1. 2022-01-21. PMID:35052650. |
finally, we hypothesize that modified amyloid and the tau protein, along with the oxidative stress generated, are new key elements in the vicious circle important in the development of post-ischemic neurodegeneration in a type of alzheimer's disease proteinopathy. |
2022-01-21 |
2023-08-13 |
Not clear |
| Le Minh Tu Phan, Sungbo Ch. Fluorescent Aptasensor and Colorimetric Aptablot for p-tau231 Detection: Toward Early Diagnosis of Alzheimer's Disease. Biomedicines. vol 10. issue 1. 2022-01-21. PMID:35052773. |
the pathology of alzheimer's disease (ad), the most common cause of dementia, is considered to be mainly driven by two major hallmarks (tau and amyloid beta). |
2022-01-21 |
2023-08-13 |
Not clear |
| Anton Meinicke, Wolfgang Härtig, Karsten Winter, Joana Puchta, Bianca Mages, Dominik Michalski, Alexander Emmer, Markus Otto, Karl-Titus Hoffmann, Willi Reimann, Matthias Krause, Stefan Scho. Surfactant Protein-G in Wildtype and 3xTg-AD Mice: Localization in the Forebrain, Age-Dependent Hippocampal Dot-like Deposits and Brain Content. Biomolecules. vol 12. issue 1. 2022-01-21. PMID:35053244. |
exploring whether sp-g might play a role in alzheimer's disease (ad), 3xtg-ad mice were investigated and displayed age-dependent hippocampal deposits of β-amyloid and hyperphosphorylated tau separately from clustered, sp-g-containing dots with additional reelin-ir-which was used as established marker for disease progression in this specific context. |
2022-01-21 |
2023-08-13 |
mouse |
| Santiago Rodriguez Ospina, Danielle M Blazier, Marangelie Criado-Marrero, Lauren A Gould, Niat T Gebru, David Beaulieu-Abdelahad, Xinming Wang, Elizabeth Remily-Wood, Dale Chaput, Stanley Stevens, Vladimir N Uversky, Paula C Bickford, Chad A Dickey, Laura J Blai. Small Heat Shock Protein 22 Improves Cognition and Learning in the Tauopathic Brain. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35055033. |
the microtubule-associated protein tau pathologically accumulates and aggregates in alzheimer's disease (ad) and other tauopathies, leading to cognitive dysfunction and neuronal loss. |
2022-01-21 |
2023-08-13 |
mouse |
| Roghayeh Jalili, Salimeh Chenaghlou, Alireza Khataee, Balal Khalilzadeh, Mohammad-Reza Rashid. An Electrochemiluminescence Biosensor for the Detection of Alzheimer's Tau Protein Based on Gold Nanostar Decorated Carbon Nitride Nanosheets. Molecules (Basel, Switzerland). vol 27. issue 2. 2022-01-21. PMID:35056745. |
an electrochemiluminescence biosensor for the detection of alzheimer's tau protein based on gold nanostar decorated carbon nitride nanosheets. |
2022-01-21 |
2023-08-13 |
human |
| Roghayeh Jalili, Salimeh Chenaghlou, Alireza Khataee, Balal Khalilzadeh, Mohammad-Reza Rashid. An Electrochemiluminescence Biosensor for the Detection of Alzheimer's Tau Protein Based on Gold Nanostar Decorated Carbon Nitride Nanosheets. Molecules (Basel, Switzerland). vol 27. issue 2. 2022-01-21. PMID:35056745. |
human tau protein is the most reliable biomarker for the prediction of alzheimer's disease (ad). |
2022-01-21 |
2023-08-13 |
human |
| Gloria S Benson, Chris Bauer, Lucrezia Hausner, Samuel Couturier, Piotr Lewczuk, Oliver Peters, Michael Hüll, Holger Jahn, Frank Jessen, Johannes Pantel, Stefan J Teipel, Michael Wagner, Johannes Schuchhardt, Jens Wiltfang, Johannes Kornhuber, Lutz Frölic. Don't forget about tau: the effects of ApoE4 genotype on Alzheimer's disease cerebrospinal fluid biomarkers in subjects with mild cognitive impairment-data from the Dementia Competence Network. Journal of neural transmission (Vienna, Austria : 1996). 2022-01-21. PMID:35061102. |
don't forget about tau: the effects of apoe4 genotype on alzheimer's disease cerebrospinal fluid biomarkers in subjects with mild cognitive impairment-data from the dementia competence network. |
2022-01-21 |
2023-08-13 |
human |
| Gloria S Benson, Chris Bauer, Lucrezia Hausner, Samuel Couturier, Piotr Lewczuk, Oliver Peters, Michael Hüll, Holger Jahn, Frank Jessen, Johannes Pantel, Stefan J Teipel, Michael Wagner, Johannes Schuchhardt, Jens Wiltfang, Johannes Kornhuber, Lutz Frölic. Don't forget about tau: the effects of ApoE4 genotype on Alzheimer's disease cerebrospinal fluid biomarkers in subjects with mild cognitive impairment-data from the Dementia Competence Network. Journal of neural transmission (Vienna, Austria : 1996). 2022-01-21. PMID:35061102. |
apoe4, the strongest genetic risk factor for alzheimer's disease (ad), has been shown to be associated with both beta-amyloid (aβ) and tau pathology, with the strongest evidence for effects on aβ, while the association between apoe4 and tau pathology remains inconsistent. |
2022-01-21 |
2023-08-13 |
human |
| Fumiko Konishi, Tadasu Furusho, Yoshiyuki Soeda, Jun Yamauchi, Shoko Kobayashi, Masatoshi Ito, Takuma Araki, Sarasa Kogure, Akihiko Takashima, Susumu Takekosh. Administration of mucuna beans (Mucuna pruriences (L.) DC. var. utilis) improves cognition and neuropathology of 3 × Tg-AD mice. Scientific reports. vol 12. issue 1. 2022-01-20. PMID:35046433. |
alzheimer's disease (ad) is a neurodegenerative disorder characterized by the accumulation of extracellular amyloid-beta peptides (aβ) resulting in senile plaques and intracellular hyperphosphorylated tau protein resulting in neurofibrillary tangles (nfts). |
2022-01-20 |
2023-08-13 |
mouse |
| Ruiqing Ni, Roger M Nitsc. Recent Developments in Positron Emission Tomography Tracers for Proteinopathies Imaging in Dementia. Frontiers in aging neuroscience. vol 13. 2022-01-20. PMID:35046791. |
the clinical utility of amyloid-β pet and the clinical validity of tau pet as diagnostic biomarker for alzheimer's disease continuum have been demonstrated. |
2022-01-20 |
2023-08-13 |
Not clear |
| Ashlyn G Johnson, James A Webster, Chadwick M Hale. Glial profiling of human tauopathy brain demonstrates enrichment of astrocytic transcripts in tau-related frontotemporal degeneration. Neurobiology of aging. vol 112. 2022-01-20. PMID:35051675. |
to understand how glia may be altered in frontotemporal degeneration with tau pathology (ftd-tau), we used a nanostring glial profiling panel to measure 770 transcripts related to glial biology in human control (n = 8), alzheimer's disease (ad) (n = 8), and ftd-tau (n = 8) dorsolateral prefrontal cortex. |
2022-01-20 |
2023-08-13 |
human |
| Xue Mi, Haiqiao Du, Xinmeng Guo, Yan Wu, Long Shen, Yukun Luo, Dekun Wang, Qiuyue Su, Rong Xiang, Shijing Yue, Songgu Wu, Junbo Gong, Zhuo Yang, Yuying Zhang, Xiaoyue Ta. Asparagine endopeptidase-targeted Ultrasound-responsive Nanobubbles Alleviate Tau Cleavage and Amyloid-β Deposition in an Alzheimer's Disease Model. Acta biomaterialia. 2022-01-19. PMID:35045359. |
asparagine endopeptidase-targeted ultrasound-responsive nanobubbles alleviate tau cleavage and amyloid-β deposition in an alzheimer's disease model. |
2022-01-19 |
2023-08-13 |
mouse |
| Martin J Dahl, Mara Mather, Markus Werkle-Bergner, Briana L Kennedy, Samuel Guzman, Kyle Hurth, Carol A Miller, Yuchuan Qiao, Yonggang Shi, Helena C Chui, John M Ringma. Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease. Neurobiology of aging. vol 112. 2022-01-19. PMID:35045380. |
locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant alzheimer's disease. |
2022-01-19 |
2023-08-13 |
human |