| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chae Kim, Tracy Haldiman, Sang-Gyun Kang, Lenka Hromadkova, Zhuang Zhuang Han, Wei Chen, Frances Lissemore, Alan Lerner, Rohan de Silva, Mark L Cohen, David Westaway, Jiri G Safa. Distinct populations of highly potent TAU seed conformers in rapidly progressing Alzheimer's disease. Science translational medicine. vol 14. issue 626. 2022-01-05. PMID:34985969. |
distinct populations of highly potent tau seed conformers in rapidly progressing alzheimer's disease. |
2022-01-05 |
2023-08-13 |
Not clear |
| Ni-Ni Chiang, Te-Hsien Lin, Yu-Shan Teng, Ying-Chieh Sun, Kuo-Hsuan Chang, Chung-Yin Lin, Hsiu Mei Hsieh-Li, Ming-Tsan Su, Chiung-Mei Chen, Guey-Jen Lee-Che. Flavones 7,8-DHF, Quercetin, and Apigenin Against Tau Toxicity Frontiers in aging neuroscience. vol 13. 2022-01-03. PMID:34975454. |
flavones 7,8-dhf, quercetin, and apigenin against tau toxicity alzheimer's disease (ad) is a progressive neurodegenerative disease with memory loss and cognitive decline. |
2022-01-03 |
2023-08-13 |
Not clear |
| Yulian Zou, Chen-Ling Gan, Zhiming Xin, Hai-Tao Zhang, Qi Zhang, Tae Ho Lee, Xiaodong Pan, Zhou Che. Programmed Cell Death Protein 1 Blockade Reduces Glycogen Synthase Kinase 3β Activity and Tau Hyperphosphorylation in Alzheimer's Disease Mouse Models. Frontiers in cell and developmental biology. vol 9. 2022-01-03. PMID:34977020. |
programmed cell death protein 1 blockade reduces glycogen synthase kinase 3β activity and tau hyperphosphorylation in alzheimer's disease mouse models. |
2022-01-03 |
2023-08-13 |
mouse |
| Vérane Achard, Kelly Ceyzériat, Benjamin B Tournier, Giovanni B Frisoni, Valentina Garibotto, Thomas Zill. Biomarkers to Evaluate Androgen Deprivation Therapy for Prostate Cancer and Risk of Alzheimer's Disease and Neurodegeneration: Old Drugs, New Concerns. Frontiers in oncology. vol 11. 2021-12-31. PMID:34970480. |
importantly, no study investigated yet biomarkers of alzheimer's disease pathology, namely amyloid and tau. |
2021-12-31 |
2023-08-13 |
Not clear |
| Samuel Walter Hersh, Yang You, Roshanak Aslebagh, Scott A Shaffer, Seiko Ikezu, Jesse Mez, Kathryn L Lunetta, Mark W Logue, Lindsay A Farrer, Tsuneya Ikez. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971140. |
alzheimer's disease associated akap9 i2558m mutation alters posttranslational modification and interactome of tau and cellular functions in crispr-edited human neuronal cells. |
2021-12-31 |
2023-08-13 |
human |
| Ankita Srivastav, Sahabudeen Sheik Mohidee. Intestinal microbial dysbiosis induced tau accumulation establishes a gut-brain correlation for pathology Alzheimer's disease in Drosophila melanogaster. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971141. |
intestinal microbial dysbiosis induced tau accumulation establishes a gut-brain correlation for pathology alzheimer's disease in drosophila melanogaster. |
2021-12-31 |
2023-08-13 |
drosophila_melanogaster |
| Ankita Srivastav, Sahabudeen Sheik Mohidee. Intestinal microbial dysbiosis induced tau accumulation establishes a gut-brain correlation for pathology Alzheimer's disease in Drosophila melanogaster. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971141. |
to study how the exposure of pseudomonas sp., a gram-negative bacteria, influences tau accumulation and neurodegeneration thereby understanding the gut-brain correlation for the pathology of alzheimer's disease. |
2021-12-31 |
2023-08-13 |
drosophila_melanogaster |
| Juliet V Santiago, Sruti Rayaprolu, Hailian Xiao, Nicholas T Seyfried, Srikant Rangaraj. Identification of state-specific proteomic characteristics of microglia-derived exosomes. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971151. |
alzheimer's disease (ad) is the most common neurodegenerative disorder defined by progressive pathological protein aggregation (amyloid-beta and tau) and deterioration of cognitive function. |
2021-12-31 |
2023-08-13 |
Not clear |
| Marangelie Criado-Marrero, Laura J Blai. CHOP is not a main contributor to tau-mediated toxicity. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971158. |
in alzheimer's disease (ad), the accumulation of the microtubule associated protein tau is linked with neuronal loss, but the major cell death pathway remains to be identified. |
2021-12-31 |
2023-08-13 |
mouse |
| Saskia J Pollack, Dina Dakkak, Tong Guo, Patricia Gómez-Suaga, Wendy Noble, Diane P Hange. Autophagy and lysosomal defects in cells expressing disease-associated tau. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971173. |
intracellular accumulation of insoluble tau is an important hallmark of alzheimer's disease (ad) and related tauopathies. |
2021-12-31 |
2023-08-13 |
mouse |
| Praveen Bathini, Tao Sun, Qiaoqiao Shi, Yongzhi Zhang, Nadine Taudte, Mathias Schenk, Thore Hettmann, Stephan Schilling, Nathan McDannold, Cynthia A Lemer. Focus Ultrasound-Induced Blood-Brain Barrier opening enhances anti-pGlu3 Aβ mAb delivery and amyloid-beta plaque clearance. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971185. |
alzheimer's disease (ad) is a neurodegenerative disorder characterized by the accumulation of amyloid plaques and hyperphosphorylated tau in the brain. |
2021-12-31 |
2023-08-13 |
mouse |
| Sarah Bachmann, Michael Bell, Mhd Aghyad Al Kabbani, Jennifer Klimek, Hans Zempe. Investigating isoform-specific functions of Tau under healthy and pathological conditions using Tau-deficient hiPSC-derived cortical neurons. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971193. |
one hallmark of many neurodegenerative diseases, such as alzheimer's disease (ad), is the formation of neurofibrillary tangles by hyperphosphorylated tau in the brain, resulting in neuronal death and cognitive decline. |
2021-12-31 |
2023-08-13 |
human |
| Yu Zou, Lulu Gua. Unraveling the Influence of K280 Acetylation on the Conformational Features of Tau Core Fragment: A Molecular Dynamics Simulation Study. Frontiers in molecular biosciences. vol 8. 2021-12-30. PMID:34966788. |
abnormal aggregation of the microtubule-associated protein tau is closely associated with tauopathies, including alzheimer's disease and chronic traumatic encephalopathy. |
2021-12-30 |
2023-08-13 |
Not clear |
| Isabel J Sible, Daniel A Natio. Visit-to-Visit Blood Pressure Variability and Longitudinal Tau Accumulation in Older Adults. Hypertension (Dallas, Tex. : 1979). 2021-12-30. PMID:34967222. |
we examined whether bpv in older adults is related to tau accumulation in brain regions vulnerable to alzheimer disease and whether relationships are modified by apoϵ4 carrier status. |
2021-12-30 |
2023-08-13 |
Not clear |
| Jeremy A Elman, Olivia K Puckett, Donald J Hagler, Rahul C Pearce, Christine Fennema-Notestine, Sean N Hatton, Michael J Lyons, Linda K McEvoy, Matthew S Panizzon, Emilie T Reas, Anders M Dale, Carol E Franz, William S Kreme. Associations Between MRI-Assessed Locus Coeruleus Integrity and Cortical Gray Matter Microstructure. Cerebral cortex (New York, N.Y. : 1991). 2021-12-30. PMID:34969072. |
the locus coeruleus (lc) is one of the earliest sites of tau pathology, making it a key structure in early alzheimer's disease (ad) progression. |
2021-12-30 |
2023-08-13 |
Not clear |
| Sushma, Amal Chandra Monda. Immunotherapeutic Approaches for the Treatment of Neurodegenerative Diseases: Challenges and Outcomes. CNS & neurological disorders drug targets. 2021-12-29. PMID:34963438. |
these proteins are amyloid-β peptide, tau, α-synuclein, and mhtt, which cause alzheimer's disease, frontotemporal dementia, corticobasal degeneration, progressive supranuclear palsy, parkinson's disease, multiple system atrophy, dementia with lewy-body and huntington's disease. |
2021-12-29 |
2023-08-13 |
Not clear |
| Beatriz G Perez-Nievas, Louisa Johnson, Paula Beltran-Lobo, Martina M Hughes, Luciana Gammallieri, Francesca Tarsitano, Monika A Myszczynska, Irina Vazquez-Villasenor, Maria Jimenez-Sanchez, Claire Troakes, Stephen B Wharton, Laura Ferraiuolo, Wendy Nobl. Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity. Journal of neuroinflammation. vol 18. issue 1. 2021-12-29. PMID:34963475. |
pathological interactions between β-amyloid (aβ) and tau drive synapse loss and cognitive decline in alzheimer's disease (ad). |
2021-12-29 |
2023-08-13 |
Not clear |
| Seung-Hye Lee, Mitchell G Rezzonico, Brad A Friedman, Melanie H Huntley, William J Meilandt, Shristi Pandey, Ying-Jiun J Chen, Amy Easton, Zora Modrusan, David V Hansen, Morgan Sheng, Christopher J Bohle. TREM2-independent oligodendrocyte, astrocyte, and T cell responses to tau and amyloid pathology in mouse models of Alzheimer disease. Cell reports. vol 37. issue 13. 2021-12-29. PMID:34965428. |
trem2-independent oligodendrocyte, astrocyte, and t cell responses to tau and amyloid pathology in mouse models of alzheimer disease. |
2021-12-29 |
2023-08-13 |
mouse |
| Adam P Mecca, Ming-Kai Chen, Ryan S O'Dell, Mika Naganawa, Takuya Toyonaga, Tyler A Godek, Joanna E Harris, Hugh H Bartlett, Wenzhen Zhao, Emmie R Banks, Gessica S Ni, Kelly Rogers, Jean Dominique Gallezot, Jim Ropchan, Paul R Emery, Nabeel B Nabulsi, Brent C Vander Wyk, Amy F T Arnsten, Yiyun Huang, Richard E Carson, Christopher H van Dyc. Association of entorhinal cortical tau deposition and hippocampal synaptic density in older individuals with normal cognition and early Alzheimer's disease. Neurobiology of aging. vol 111. 2021-12-28. PMID:34963063. |
association of entorhinal cortical tau deposition and hippocampal synaptic density in older individuals with normal cognition and early alzheimer's disease. |
2021-12-28 |
2023-08-13 |
human |
| Kejia Zhang, Zehui Sun, Xinyu Chen, Yifan Zhang, Angyang Guo, Yan Zhan. Intercellular transport of Tau protein and β-amyloid mediated by tunneling nanotubes. American journal of translational research. vol 13. issue 11. 2021-12-27. PMID:34956469. |
moreover, we investigated the transport of the tau protein and β-amyloid (aβ), which are both closely related to alzheimer's disease (ad) pathology, through tnts. |
2021-12-27 |
2023-08-13 |
Not clear |