All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Mitchel A Kling, Dayan B Goodenowe, Vijitha Senanayake, Siamak MahmoudianDehkordi, Matthias Arnold, Tyler J Massaro, Rebecca Baillie, Xianlin Han, Yuk-Yee Leung, Andrew J Saykin, Kwangsik Nho, Alexandra Kueider-Paisley, Jessica D Tenenbaum, Li-San Wang, Leslie M Shaw, John Q Trojanowski, Rima F Kaddurah-Daou. Circulating ethanolamine plasmalogen indices in Alzheimer's disease: Relation to diagnosis, cognition, and CSF tau. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 16. issue 9. 2021-11-19. PMID:32715599. circulating ethanolamine plasmalogen indices in alzheimer's disease: relation to diagnosis, cognition, and csf tau. 2021-11-19 2023-08-13 Not clear
Mette Habekost, Per Qvist, Mark Denham, Ida E Holm, Arne Lund Jørgense. Directly Reprogrammed Neurons Express MAPT and APP Splice Variants Pertinent to Ageing and Neurodegeneration. Molecular neurobiology. vol 58. issue 5. 2021-11-19. PMID:33415685. to model alzheimer's disease and other tauopathies, it is essential that alternative splicing of the mapt transcript in these neurons produces the relevant tau isoforms. 2021-11-19 2023-08-13 human
Charles Arber, Argyro Alatza, Claire A Leckey, Ross W Paterson, Henrik Zetterberg, Selina Wra. Mass spectrometry analysis of tau and amyloid-beta in iPSC-derived models of Alzheimer's disease and dementia. Journal of neurochemistry. vol 159. issue 2. 2021-11-19. PMID:33539581. mass spectrometry analysis of tau and amyloid-beta in ipsc-derived models of alzheimer's disease and dementia. 2021-11-19 2023-08-13 human
Jenna N Adams, Anne Maass, David Berron, Theresa M Harrison, Suzanne L Baker, Wesley P Thomas, Morgan Stanfill, William J Jagus. Reduced Repetition Suppression in Aging is Driven by Tau-Related Hyperactivity in Medial Temporal Lobe. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 17. 2021-11-19. PMID:33731446. tau deposition begins in the medial temporal lobe (mtl) in aging and alzheimer's disease (ad), and mtl neural dysfunction is commonly observed in these groups. 2021-11-19 2023-08-13 human
Ryszard Pluta, Stanisław J Czuczwar, Sławomir Januszewski, Mirosław Jabłońsk. The Many Faces of Post-Ischemic Tau Protein in Brain Neurodegeneration of the Alzheimer's Disease Type. Cells. vol 10. issue 9. 2021-11-19. PMID:34571862. the many faces of post-ischemic tau protein in brain neurodegeneration of the alzheimer's disease type. 2021-11-19 2023-08-13 Not clear
Ryszard Pluta, Stanisław J Czuczwar, Sławomir Januszewski, Mirosław Jabłońsk. The Many Faces of Post-Ischemic Tau Protein in Brain Neurodegeneration of the Alzheimer's Disease Type. Cells. vol 10. issue 9. 2021-11-19. PMID:34571862. recent data suggest that post-ischemic brain neurodegeneration in humans and animals is associated with the modified tau protein in a manner typical of alzheimer's disease neuropathology. 2021-11-19 2023-08-13 Not clear
Ryszard Pluta, Stanisław J Czuczwar, Sławomir Januszewski, Mirosław Jabłońsk. The Many Faces of Post-Ischemic Tau Protein in Brain Neurodegeneration of the Alzheimer's Disease Type. Cells. vol 10. issue 9. 2021-11-19. PMID:34571862. pathological changes in the tau protein, at the gene and protein level due to cerebral ischemia, can lead to the development of alzheimer's disease-type neuropathology and dementia. 2021-11-19 2023-08-13 Not clear
Ryszard Pluta, Stanisław J Czuczwar, Sławomir Januszewski, Mirosław Jabłońsk. The Many Faces of Post-Ischemic Tau Protein in Brain Neurodegeneration of the Alzheimer's Disease Type. Cells. vol 10. issue 9. 2021-11-19. PMID:34571862. in this review, we update our understanding of proteomic and genomic changes in the tau protein in post-ischemic brain injury and present the relationship between the modified tau protein and post-ischemic neuropathology and present a positive correlation between the modified tau protein and a post-ischemic neuropathology that has characteristics of alzheimer's disease-type neurodegeneration. 2021-11-19 2023-08-13 Not clear
Brian Spencer, Robert A Rissman, Cassia Overk, Eliezer Maslia. Novel Brain-Penetrating Single Chain Antibodies Directed Against 3RTau for the Treatment of Alzheimer's Disease and Related Dementias. Methods in molecular biology (Clifton, N.J.). vol 2383. 2021-11-19. PMID:34766306. alzheimer's disease (ad), pick's disease, fronto-temporal lobar degeneration, cortico-basal degeneration, and primary age related tauopathy are examples of neurodegenerative disorders with tau accumulation and jointly referred as "tauopathies." 2021-11-19 2023-08-13 Not clear
Akram Tayanloo-Beik, Zahra Kiasalari, Mehrdad Roghan. Paeonol Ameliorates Cognitive Deficits in Streptozotocin Murine Model of Sporadic Alzheimer's Disease via Attenuation of Oxidative Stress, Inflammation, and Mitochondrial Dysfunction. Journal of molecular neuroscience : MN. 2021-11-19. PMID:34797511. intracerebroventricular (icv) microinjection of diabetogenic drug streptozotocin (stz) in rodents consistently produces a model of sporadic alzheimer's disease (sad) which is characterized by tau pathology and concomitant cognitive decline, insulin resistance, neuroinflammation, oxidative stress, and mitochondrial malfunction. 2021-11-19 2023-08-13 rat
Jogeshwar Mukherjee, Christopher Liang, Krystal K Patel, Phuc Q Lam, Rommani Monda. Development and evaluation of [ Synapse (New York, N.Y.). vol 75. issue 1. 2021-11-18. PMID:32722889. development and evaluation of [ alzheimer's disease (ad) is a neurodegenerative disease characterized by aggregation of tau protein into paired helical filaments causing neurofibrillary tangles (nft) in the brain. 2021-11-18 2023-08-13 Not clear
Minli Yan, Tingting Zhen. Role of the endolysosomal pathway and exosome release in tau propagation. Neurochemistry international. vol 145. 2021-11-18. PMID:33582164. the progressive deposition of misfolded and aggregated forms of tau protein in the brain is a pathological hallmark of tauopathies, such as alzheimer's disease (ad) and frontotemporal degeneration (ftd). 2021-11-18 2023-08-13 Not clear
Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou, Dingwei Zhou, Ruozhen Wu, Dandan Chu, Nana Jin, Kevin Deng, Jiawei Xu, Cheng-Xin Gong, Khalid Iqbal, Fei Li. Alzheimer's disease brain contains tau fractions with differential prion-like activities. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33597014. alzheimer's disease brain contains tau fractions with differential prion-like activities. 2021-11-18 2023-08-13 Not clear
Longfei Li, Ruirui Shi, Jianlan Gu, Yunn Chyn Tung, Yan Zhou, Dingwei Zhou, Ruozhen Wu, Dandan Chu, Nana Jin, Kevin Deng, Jiawei Xu, Cheng-Xin Gong, Khalid Iqbal, Fei Li. Alzheimer's disease brain contains tau fractions with differential prion-like activities. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33597014. neurofibrillary tangles (nfts) made of abnormally hyperphosphorylated tau are a hallmark of alzheimer's disease (ad) and related tauopathies. 2021-11-18 2023-08-13 Not clear
Vivek K Sharma, Thakur G Sing. CREB: A Multifaceted Target for Alzheimer's Disease. Current Alzheimer research. vol 17. issue 14. 2021-11-18. PMID:33602089. alzheimer's disease (ad) is a persistent neuropathological stipulation manifested in the form of neuronal/synapse demise, the formation of senile plaques, hyperphosphorylated tau tangles, neuroinflammation, and apoptotic cell death. 2021-11-18 2023-08-13 Not clear
Rinie Bajracharya, David Brici, Liviu-Gabriel Bodea, Phillip W Janowicz, Jürgen Götz, Rebecca M Nisbe. Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33712083. one of the main pathological hallmarks of alzheimer's disease (ad) is the intraneuronal accumulation of hyperphosphorylated tau. 2021-11-18 2023-08-13 mouse
Valentina Latina, Giacomo Giacovazzo, Federica Cordella, Bijorn Omar Balzamino, Alessandra Micera, Monica Varano, Cristina Marchetti, Francesca Malerba, Rita Florio, Bruno Bruni Ercole, Federico La Regina, Anna Atlante, Roberto Coccurello, Silvia Di Angelantonio, Pietro Calissano, Giuseppina Amador. Systemic delivery of a specific antibody targeting the pathological N-terminal truncated tau peptide reduces retinal degeneration in a mouse model of Alzheimer's Disease. Acta neuropathologica communications. vol 9. issue 1. 2021-11-18. PMID:33750467. systemic delivery of a specific antibody targeting the pathological n-terminal truncated tau peptide reduces retinal degeneration in a mouse model of alzheimer's disease. 2021-11-18 2023-08-13 mouse
Ying-Da Chen, Po-Yuan Huang, Chien-Sung Chiang, Yi-Shuian Huang, Sung-Chun Tan. Generation and Role of Calpain-Cleaved 17-kDa Tau Fragment in Acute Ischemic Stroke. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34414533. the generation of a 17-kda neurotoxic tau fragment was reported in alzheimer's disease but it has not been well studied in stroke. 2021-11-18 2023-08-13 human
Yang Shi, Wenjuan Zhang, Yang Yang, Alexey G Murzin, Benjamin Falcon, Abhay Kotecha, Mike van Beers, Airi Tarutani, Fuyuki Kametani, Holly J Garringer, Ruben Vidal, Grace I Hallinan, Tammaryn Lashley, Yuko Saito, Shigeo Murayama, Mari Yoshida, Hidetomo Tanaka, Akiyoshi Kakita, Takeshi Ikeuchi, Andrew C Robinson, David M A Mann, Gabor G Kovacs, Tamas Revesz, Bernardino Ghetti, Masato Hasegawa, Michel Goedert, Sjors H W Schere. Structure-based classification of tauopathies. Nature. vol 598. issue 7880. 2021-11-18. PMID:34588692. it was previously reported that, by cryo-electron microscopy, the structures of tau filaments from alzheimer's disease 2021-11-18 2023-08-13 Not clear
Liang Chen, Yi-Ping Zhou, Hua-Yi Liu, Juan-Hua Gu, Xin-Fu Zhou, Zeng Yue-Qi. Long-term oral administration of hyperoside ameliorates AD-related neuropathology and improves cognitive impairment in APP/PS1 transgenic mice. Neurochemistry international. vol 151. 2021-11-18. PMID:34601013. alzheimer's disease (ad) is a highly prevalent neurodegenerative disorder characterized by the pathological hallmarks of β-amyloid plaque deposits, tau pathology, inflammation, and cognitive decline. 2021-11-18 2023-08-13 mouse