All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Myeongsu Na, Kitae Kim, Hye Ryeong Lim, Chang Man Ha, Sunghoe Chan. Rapid immunostaining method for three-dimensional volume imaging of biological tissues by magnetic force-induced focusing of the electric field. Brain structure & function. vol 226. issue 1. 2021-10-05. PMID:33175320. efic stained tau deposits and the vascular structure in the post-mortem human brain of alzheimer's disease and intracerebral hemorrhage, respectively, enabling quantitative analysis. 2021-10-05 2023-08-13 human
Amanda Ferreira Neves, Christian Camargo, Courtney Premer, Joshua M Hare, Bernard S Baumel, Milena Pint. Intravenous administration of mesenchymal stem cells reduces Tau phosphorylation and inflammation in the 3xTg-AD mouse model of Alzheimer's disease. Experimental neurology. vol 341. 2021-10-04. PMID:33757765. intravenous administration of mesenchymal stem cells reduces tau phosphorylation and inflammation in the 3xtg-ad mouse model of alzheimer's disease. 2021-10-04 2023-08-13 mouse
Ahlam S Soliman, Andrew Umstead, Tessa Grabinski, Nicholas M Kanaan, Andy Lee, John Ryan, Jared Lamp, Irving E Veg. EFhd2 brain interactome reveals its association with different cellular and molecular processes. Journal of neurochemistry. 2021-10-04. PMID:34543436. we have shown that efhd2 interacts with tau protein, a key pathological hallmark in alzheimer's disease and related dementias. 2021-10-04 2023-08-13 mouse
Tzu-An Song, Samadrita Roy Chowdhury, Fan Yang, Heidi I L Jacobs, Jorge Sepulcre, Van J Wedeen, Keith A Johnson, Joyita Dutt. A physics-informed geometric learning model for pathological tau spread in Alzheimer's disease. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 12267. 2021-10-02. PMID:33263115. a physics-informed geometric learning model for pathological tau spread in alzheimer's disease. 2021-10-02 2023-08-13 Not clear
Tzu-An Song, Samadrita Roy Chowdhury, Fan Yang, Heidi I L Jacobs, Jorge Sepulcre, Van J Wedeen, Keith A Johnson, Joyita Dutt. A physics-informed geometric learning model for pathological tau spread in Alzheimer's disease. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 12267. 2021-10-02. PMID:33263115. tau tangles are a pathophysiological hallmark of alzheimer's disease (ad) and exhibit a stereotypical pattern of spatiotemporal spread which has strong links to disease progression and cognitive decline. 2021-10-02 2023-08-13 Not clear
Joshua D Cho, Yoon A Kim, Elizabeth E Rafikian, Mu Yang, Ismael Santa-Mari. Marked Mild Cognitive Deficits in Humanized Mouse Model of Alzheimer's-Type Tau Pathology. Frontiers in behavioral neuroscience. vol 15. 2021-10-02. PMID:34093145. hyperphosphorylation and the subsequent aggregation of tau protein into neurofibrillary tangles (nfts) are well-established neuropathological hallmarks of alzheimer's disease (ad) and associated tauopathies. 2021-10-02 2023-08-13 mouse
Yari Carlomagno, Sireesha Manne, Michael DeTure, Mercedes Prudencio, Yong-Jie Zhang, Rana Hanna Al-Shaikh, Judith A Dunmore, Lillian M Daughrity, Yuping Song, Monica Castanedes-Casey, Laura J Lewis-Tuffin, Katharine A Nicholson, Zbigniew K Wszolek, Dennis W Dickson, Anthony W P Fitzpatrick, Leonard Petrucelli, Casey N Coo. The AD tau core spontaneously self-assembles and recruits full-length tau to filaments. Cell reports. vol 34. issue 11. 2021-10-01. PMID:33730588. tau accumulation is a major pathological hallmark of alzheimer's disease (ad) and other tauopathies, but the mechanism(s) of tau aggregation remains unclear. 2021-10-01 2023-08-13 Not clear
Abhishek Ankur Balmik, Shweta Kishor Sonawane, Subashchandrabose Chinnathamb. The extracellular HDAC6 ZnF UBP domain modulates the actin network and post-translational modifications of Tau. Cell communication and signaling : CCS. vol 19. issue 1. 2021-10-01. PMID:33933071. microtubule-associated protein tau undergoes aggregation in alzheimer`s disease (ad) and a group of other related diseases collectively known as tauopathies. 2021-10-01 2023-08-13 Not clear
Abhishek Ankur Balmik, Subashchandrabose Chinnathamb. Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer's disease. Cell communication and signaling : CCS. vol 19. issue 1. 2021-10-01. PMID:33962636. methylation as a key regulator of tau aggregation and neuronal health in alzheimer's disease. 2021-10-01 2023-08-13 Not clear
Abhishek Ankur Balmik, Subashchandrabose Chinnathamb. Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer's disease. Cell communication and signaling : CCS. vol 19. issue 1. 2021-10-01. PMID:33962636. alzheimer disease is associated with the aggregation and accumulation of two major protein aggregates-intracellular neurofibrillary tangles made up of microtubule-associated protein tau and extracellular amyloid-β plaques. 2021-10-01 2023-08-13 Not clear
Kemeng Pan, Song Chen, Yue Wang, Wenbing Yao, Xiangdong Ga. MicroRNA-23b attenuates tau pathology and inhibits oxidative stress by targeting GnT-III in Alzheimer's disease. Neuropharmacology. vol 196. 2021-10-01. PMID:34153312. microrna-23b attenuates tau pathology and inhibits oxidative stress by targeting gnt-iii in alzheimer's disease. 2021-10-01 2023-08-13 mouse
Kemeng Pan, Song Chen, Yue Wang, Wenbing Yao, Xiangdong Ga. MicroRNA-23b attenuates tau pathology and inhibits oxidative stress by targeting GnT-III in Alzheimer's disease. Neuropharmacology. vol 196. 2021-10-01. PMID:34153312. alzheimer's disease (ad) is a neurodegenerative disease, the main pathological features include deposition of neurofibrillary tangles composed of the abnormally hyperphosphorylated tau protein and plaques deposition composed of β-amyloid (aβ) peptide. 2021-10-01 2023-08-13 mouse
Michel J Grothe, Alexis Moscoso, Nicholas J Ashton, Thomas K Karikari, Juan Lantero-Rodriguez, Anniina Snellman, Henrik Zetterberg, Kaj Blennow, Michael Schöl. Associations of Fully Automated CSF and Novel Plasma Biomarkers With Alzheimer Disease Neuropathology at Autopsy. Neurology. 2021-10-01. PMID:34266917. to study cerebrospinal fluid (csf) biomarkers of alzheimer's disease (ad) analyzed by fully automated elecsys immunoassays in comparison to neuropathologic gold standards, and compare their accuracy to plasma phosphorylated tau (p-tau181) measured using a novel simoa method. 2021-10-01 2023-08-13 Not clear
Xieze Wei, Pengchong Du, Zhiying Zha. Impacts of DNA methylation on Tau protein related genes in the brains of patients with Alzheimer's disease. Neuroscience letters. vol 763. 2021-10-01. PMID:34437990. impacts of dna methylation on tau protein related genes in the brains of patients with alzheimer's disease. 2021-10-01 2023-08-13 Not clear
Xieze Wei, Pengchong Du, Zhiying Zha. Impacts of DNA methylation on Tau protein related genes in the brains of patients with Alzheimer's disease. Neuroscience letters. vol 763. 2021-10-01. PMID:34437990. in this paper, the process and role of gene methylation in abnormal tau modification and aggregation in the development of alzheimer's disease were discussed. 2021-10-01 2023-08-13 Not clear
Xieze Wei, Pengchong Du, Zhiying Zha. Impacts of DNA methylation on Tau protein related genes in the brains of patients with Alzheimer's disease. Neuroscience letters. vol 763. 2021-10-01. PMID:34437990. the effect of dna methylation on tau protein in the brain of patients with alzheimer's disease will help to find new targets in the development of drugs for treating alzheimer's disease. 2021-10-01 2023-08-13 Not clear
Cristina M Pedrero-Prieto, Javier Frontiñán-Rubio, Francisco J Alcaín, Mario Durán-Prado, Juan R Peinado, Yoana Rabanal-Rui. Biological Significance of the Protein Changes Occurring in the Cerebrospinal Fluid of Alzheimer's Disease Patients: Getting Clues from Proteomic Studies. Diagnostics (Basel, Switzerland). vol 11. issue 9. 2021-10-01. PMID:34573996. during the last decade, biomarker discovery has been especially fruitful for the identification new proteins that appear in the csf of alzheimer's disease (ad) patients together with amyloid-β (aβ42), total tau (t-tau), and phosphorylated tau (p-tau). 2021-10-01 2023-08-13 Not clear
Peng Wang, Yihong Y. Astrocytes in Neurodegenerative Diseases: A Perspective from Tauopathy and α-Synucleinopathy. Life (Basel, Switzerland). vol 11. issue 9. 2021-10-01. PMID:34575087. this review summarizes our current understanding of the complex molecular interplays between astrocyte and neuron, emphasizing on tau and α-synuclein (α-syn), the disease-driving proteins for alzheimer's and parkinson's diseases, respectively. 2021-10-01 2023-08-13 Not clear
Chih Hung L. Recent advances in cellular biosensor technology to investigate tau oligomerization. Bioengineering & translational medicine. vol 6. issue 3. 2021-10-01. PMID:34589603. tau is a microtubule binding protein which plays an important role in physiological functions but it is also involved in the pathogenesis of alzheimer's disease and related tauopathies. 2021-10-01 2023-08-13 Not clear
Qingqin S Li, Louis De Muync. Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1. Brain, behavior, & immunity - health. vol 13. 2021-10-01. PMID:34589742. alzheimer's disease (ad) is associated with abnormal tau and amyloid-β accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and extracellular amyloid-β plaques. 2021-10-01 2023-08-13 Not clear