All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Yan-Juan Wang, Wei-Gang Gong, Qing-Guo Ren, Zhi-Jun Zhan. Escitalopram Alleviates Alzheimer's Disease-Type Tau Pathologies in the Aged P301L Tau Transgenic Mice. Journal of Alzheimer's disease : JAD. vol 77. issue 2. 2021-09-09. PMID:32741828. escitalopram alleviates alzheimer's disease-type tau pathologies in the aged p301l tau transgenic mice. 2021-09-09 2023-08-13 mouse
Yan-Juan Wang, Wei-Gang Gong, Qing-Guo Ren, Zhi-Jun Zhan. Escitalopram Alleviates Alzheimer's Disease-Type Tau Pathologies in the Aged P301L Tau Transgenic Mice. Journal of Alzheimer's disease : JAD. vol 77. issue 2. 2021-09-09. PMID:32741828. the inhibition of tau hyperphosphorylation is one of the most promising therapeutic targets for the development of alzheimer's disease (ad) modifying drugs. 2021-09-09 2023-08-13 mouse
Shalini S Rao, Stuart D Portbury, Larissa Lago, Gawain McColl, David I Finkelstein, Ashley I Bush, Paul A Adlar. The Iron Chelator Deferiprone Improves the Phenotype in a Mouse Model of Tauopathy. Journal of Alzheimer's disease : JAD. vol 77. issue 2. 2021-09-09. PMID:32741833. abnormally hyperphosphorylated tau is a defining pathological feature of tauopathies, such as alzheimer's disease (ad), and accumulating evidence suggests a role for iron in mediating tau pathology that may lead to cognitive decline in these conditions. 2021-09-09 2023-08-13 mouse
Bin Zhao, Yi Wang, Rui Liu, Xiao-Li Jia, Nan Hu, Xing-Wei An, Chen-Guang Zheng, Chong Chen, Hong-Tao Sun, Feng Chen, Jing-Jing Wang, Xiao-Hong L. Rutaecarpine Ameliorated High Sucrose-Induced Alzheimer's Disease Like Pathological and Cognitive Impairments in Mice. Rejuvenation research. vol 24. issue 3. 2021-09-09. PMID:32892706. high sucrose can induce tau hyperphosphorylation and cognitive dysfunction/memory impairment as observed in alzheimer's disease (ad). 2021-09-09 2023-08-13 mouse
Giulia Montalto, Francesca Caudano, Laura Sturla, Santina Bruzzone, Annalisa Salis, Gianluca Damonte, Jos Prickaerts, Ernesto Fedele, Roberta Ricciarell. Protein kinase G phosphorylates the Alzheimer's disease-associated tau protein at distinct Ser/Thr sites. BioFactors (Oxford, England). vol 47. issue 1. 2021-09-09. PMID:33469985. protein kinase g phosphorylates the alzheimer's disease-associated tau protein at distinct ser/thr sites. 2021-09-09 2023-08-13 Not clear
Giulia Montalto, Francesca Caudano, Laura Sturla, Santina Bruzzone, Annalisa Salis, Gianluca Damonte, Jos Prickaerts, Ernesto Fedele, Roberta Ricciarell. Protein kinase G phosphorylates the Alzheimer's disease-associated tau protein at distinct Ser/Thr sites. BioFactors (Oxford, England). vol 47. issue 1. 2021-09-09. PMID:33469985. intraneuronal accumulation of hyperphosphorylated tau is a pathological hallmark of several neurodegenerative disorders, including alzheimer's disease. 2021-09-09 2023-08-13 Not clear
P Huang, M Xu, Y-X H. MicroRNA-146a regulates the expression of the Aβ1-42 protein in Alzheimer's disease. European review for medical and pharmacological sciences. vol 25. issue 4. 2021-09-09. PMID:33660812. to investigate the expression and clinical significance of microrna-146a, aβ1-42, and tau protein in the peripheral blood of patients with alzheimer's disease (ad). 2021-09-09 2023-08-13 Not clear
Jamie M Walker, Yelena Fudym, Kurt Farrell, Megan A Iida, Kevin F Bieniek, Sudha Seshadri, Charles L White, John F Crary, Timothy E Richardso. Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease. Journal of neuropathology and experimental neurology. vol 80. issue 5. 2021-09-09. PMID:33860327. asymmetry of hippocampal tau pathology in primary age-related tauopathy and alzheimer disease. 2021-09-09 2023-08-13 Not clear
Pratishtha Chatterjee, Steve Pedrini, Nicholas J Ashton, Michelle Tegg, Kathryn Goozee, Abhay K Singh, Thomas K Karikari, Joel Simrén, Eugeen Vanmechelen, Nicola J Armstrong, Eugene Hone, Prita R Asih, Kevin Taddei, Vincent Doré, Victor L Villemagne, Hamid R Sohrabi, Henrik Zetterberg, Colin L Masters, Kaj Blennow, Ralph N Martin. Diagnostic and prognostic plasma biomarkers for preclinical Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-09-09. PMID:34494715. this study involved a parallel comparison of the diagnostic and longitudinal monitoring potential of plasma glial fibrillary acidic protein (gfap), total tau (t-tau), phosphorylated tau (p-tau181 and p-tau231), and neurofilament light (nfl) in preclinical alzheimer's disease (ad). 2021-09-09 2023-08-13 Not clear
Karolin Yanar, Mehmet Can Atayik, Bahadir Simsek, Ufuk Çakata. Novel biomarkers for the evaluation of aging-induced proteinopathies. Biogerontology. vol 21. issue 5. 2021-09-08. PMID:32274599. protein misfolding and accumulation of aberrant proteins are known to be associated with aging-induced proteinopathies such as amyloid ß and tau proteins in alzheimer's disease, α-synuclein in parkinson's disease and islet amyloid polypeptides in type 2 diabetes mellitus. 2021-09-08 2023-08-13 Not clear
Ian W Weidling, Heather M Wilkins, Scott J Koppel, Lewis Hutfles, Xiaowan Wang, Anuradha Kalani, Blaise W Menta, Benjamin Ryan, Judit Perez-Ortiz, T Chris Gamblin, Russell H Swerdlo. Mitochondrial DNA Manipulations Affect Tau Oligomerization. Journal of Alzheimer's disease : JAD. vol 77. issue 1. 2021-09-08. PMID:32804126. mitochondrial dysfunction and tau aggregation occur in alzheimer's disease (ad), and exposing cells or rodents to mitochondrial toxins alters their tau. 2021-09-08 2023-08-13 Not clear
Xin Wang, En-Jie Liu, Qian Liu, Shi-Hong Li, Ting Li, Qiu-Zhi Zhou, Yan-Chao Liu, Huaqiu Zhang, Jian-Zhi Wan. Tau Acetylation in Entorhinal Cortex Induces its Chronic Hippocampal Propagation and Cognitive Deficits in Mice. Journal of Alzheimer's disease : JAD. vol 77. issue 1. 2021-09-08. PMID:32804150. increased tau acetylation at k174, k274, k280, and k281 has been observed in the brains of alzheimer's disease (ad) patients or in transgenic mice, but the role of acetylation in tau propagation is elusive. 2021-09-08 2023-08-13 mouse
Clark Funnell, Howard H Feldman, Ian R A Mackenzie, Mari L DeMarc. Applying the Alzheimer Disease ATN Diagnostic Framework in Atypical Dementia. Alzheimer disease and associated disorders. vol 34. issue 4. 2021-09-08. PMID:33215886. cerebrospinal fluid (csf) biomarkers amyloid-β and tau have been validated for the antemortem diagnosis of alzheimer disease (ad) and are included in the at(n) research framework for ad. 2021-09-08 2023-08-13 Not clear
Jinwang Ye, Ying Yin, Yaling Yin, Huaqiu Zhang, Huali Wan, Lu Wang, Yue Zuo, Di Gao, Mengzhu Li, Jun Li, Yanchao Liu, Dan Ke, Jian-Zhi Wan. Tau-induced upregulation of C/EBPβ-TRPC1-SOCE signaling aggravates tauopathies: A vicious cycle in Alzheimer neurodegeneration. Aging cell. vol 19. issue 9. 2021-09-07. PMID:32815315. intracellular accumulating of the hyperphosphorylated tau plays a pivotal role in neurodegeneration of alzheimer disease (ad), but the mechanisms underlying the gradually aggravated tau hyperphosphorylation remain elusive. 2021-09-07 2023-08-13 Not clear
Matteo Manca, Allison Krau. Defining the Protein Seeds of Neurodegeneration using Real-Time Quaking-Induced Conversion Assays. Biomolecules. vol 10. issue 9. 2021-09-07. PMID:32854212. to date, rt-quic assays have been developed for the detection of protein seeds related to known prion diseases of mammals, the αsyn aggregates of parkinson's disease, dementia with lewy bodies, and multiple system atrophy, and the tau aggregates of alzheimer's disease, chronic traumatic encephalopathy, and other tauopathies including progressive supranuclear palsy. 2021-09-07 2023-08-13 human
b' Preethy Sasidharan Nair, Pirre Raijas, Minna Ahvenainen, Anju K Philips, Liisa Ukkola-Vuoti, Irma J\\xc3\\xa4rvel\\xc3\\xa. Music-listening regulates human microRNA expression. Epigenetics. vol 16. issue 5. 2021-09-07. PMID:32867562.' mir-132 plays a critical role in regulating tau protein levels and is important for preventing tau protein aggregation that causes alzheimer's disease. 2021-09-07 2023-08-13 human
Juan Ramón Perea, Marta Bolós, Jesús Avil. Microglia in Alzheimer's Disease in the Context of Tau Pathology. Biomolecules. vol 10. issue 10. 2021-09-07. PMID:33066368. microglia in alzheimer's disease in the context of tau pathology. 2021-09-07 2023-08-13 Not clear
Jin Yu, Hong Zhu, Saeid Taheri, William Mondy, Stephen Perry, Cheryl Kirstein, Mark S Kind. Effects of GrandFusion Diet on Cognitive Impairment in Transgenic Mouse Model of Alzheimer's Disease. Nutrients. vol 13. issue 1. 2021-09-07. PMID:33396967. alzheimer's disease (ad) is the result of the deposition of amyloid β (aβ) peptide into amyloid fibrils and tau into neurofibrillary tangles. 2021-09-07 2023-08-13 mouse
Yunna Kim, Seung-Hun Ch. Lindera glauca Blume ameliorates amyloid-β Neurochemistry international. vol 147. 2021-09-07. PMID:34000331. lindera glauca blume ameliorates amyloid-β alzheimer's disease (ad) is a neurodegenerative disorder presenting cognitive decline accompanied by deposits of amyloid-β (aβ) and tau hyperphosphorylation. 2021-09-07 2023-08-13 mouse
Sofia Bergström, Julia Remnestål, Jamil Yousef, Jennie Olofsson, Ioanna Markaki, Stephanie Carvalho, Jean-Christophe Corvol, Kim Kultima, Lena Kilander, Malin Löwenmark, Martin Ingelsson, Kaj Blennow, Henrik Zetterberg, Bengt Nellgård, Frederic Brosseron, Michael T Heneka, Beatriz Bosch, Raquel Sanchez-Valle, Anna Månberg, Per Svenningsson, Peter Nilsso. Multi-cohort profiling reveals elevated CSF levels of brain-enriched proteins in Alzheimer's disease. Annals of clinical and translational neurology. vol 8. issue 7. 2021-09-07. PMID:34129723. decreased amyloid beta (aβ) 42 together with increased tau and phospho-tau in cerebrospinal fluid (csf) is indicative of alzheimer's disease (ad). 2021-09-07 2023-08-13 Not clear