Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ryszard Pluta, Liang Ouyang, Sławomir Januszewski, Yang Li, Stanisław J Czuczwa. Participation of Amyloid and Tau Protein in Post-Ischemic Neurodegeneration of the Hippocampus of a Nature Identical to Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 5. 2021-05-12. PMID:33671097. |
participation of amyloid and tau protein in post-ischemic neurodegeneration of the hippocampus of a nature identical to alzheimer's disease. |
2021-05-12 |
2023-08-13 |
Not clear |
Connor M Wander, Jui-Heng Tseng, Sheng Song, Heba A Al Housseiny, Dalton S Tart, Aditi Ajit, Yen-Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B Meeker, David J Irwin, Todd J Cohe. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. iScience. vol 23. issue 7. 2021-05-11. PMID:32585593. |
the microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including alzheimer's disease (ad). |
2021-05-11 |
2023-08-13 |
mouse |
Allal Boutajangout, Wei Zhang, Justin Kim, Wed Ali Abdali, Frances Prelli, Thomas Wisniewsk. Passive Immunization With a Novel Monoclonal Anti-PrP Antibody TW1 in an Alzheimer's Mouse Model With Tau Pathology. Frontiers in aging neuroscience. vol 13. 2021-05-11. PMID:33716717. |
passive immunization with a novel monoclonal anti-prp antibody tw1 in an alzheimer's mouse model with tau pathology. |
2021-05-11 |
2023-08-13 |
mouse |
Ruihua Sun, Huayuan Wang, Yingying Shi, Zhikun Sun, Haisong Jiang, Jiewen Zhan. Changes in the Morphology, Number, and Pathological Protein Levels of Plasma Exosomes May Help Diagnose Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884461. |
recent studies have shown that exosomes contain both amyloid-β (aβ) and tau proteins and have a controversial role in the alzheimer's disease (ad) process. |
2021-05-10 |
2023-08-13 |
Not clear |
Yanying Liu, Hongmin Wan. Modeling Sporadic Alzheimer's Disease by Efficient Direct Reprogramming of the Elderly Derived Disease Dermal Fibroblasts into Neural Stem Cells. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884463. |
alzheimer's disease (ad) is a devastating neurodegenerative disorder, neuropathologically characterized by hyperphosphorylation of tau and formation of amyloid plaques. |
2021-05-10 |
2023-08-13 |
Not clear |
Shweta Kishor Sonawane, Subashchandrabose Chinnathamb. P301 L, an FTDP-17 Mutant, Exhibits Enhanced Glycation in vitro. Journal of Alzheimer's disease : JAD. vol 75. issue 1. 2021-05-10. PMID:32250308. |
alzheimer's disease is a non-primary tauopathy, which displays tau neuropathology of excess tangle formation and accumulation. |
2021-05-10 |
2023-08-13 |
Not clear |
Ho Jae Lim, Jung Eun Park, Byeong C Kim, Seong-Min Choi, Min-Kyung Song, Soo Hyun Cho, Hyeon Jeong Seo, Jahae Kim, Ho-Chun Song, Kyu Yeong Choi, Jang Jae Lee, Hoo-Won Kim, Jung-Min Ha, Woo Keun Song, Sung-Gyoo Park, Jung Sup Lee, Kun Ho Le. Comparison of Two Analytical Platforms in Cerebrospinal Fluid Biomarkers for the Classification of Alzheimer's Disease Spectrum with Amyloid PET Imaging. Journal of Alzheimer's disease : JAD. vol 75. issue 3. 2021-05-10. PMID:32390627. |
cerebrospinal fluid (csf) amyloid-β1-42 (aβ1-42), total tau protein (t-tau), and phosphorylated tau (p-tau) are atn biomarkers for alzheimer's disease (ad) and reflect pathogenic changes in the brain. |
2021-05-10 |
2023-08-13 |
Not clear |
Phuong H Nguyen, Philippe Derreumau. Structures of the intrinsically disordered Aβ, tau and α-synuclein proteins in aqueous solution from computer simulations. Biophysical chemistry. vol 264. 2021-05-10. PMID:32623047. |
the aβ and tau proteins, and the α-synuclein protein, key players in alzheimer's and parkinson's diseases, respectively are fully disordered at the monomer level. |
2021-05-10 |
2023-08-13 |
human |
Michael G Friedrich, Amanda Skora, Sarah E Hancock, Todd W Mitchell, Paul L Else, Roger J W Truscot. Tau Is Truncated in Five Regions of the Normal Adult Human Brain. International journal of molecular sciences. vol 22. issue 7. 2021-05-10. PMID:33805376. |
the truncation of tau is thought to be important in promoting aggregation, with this feature characterising the pathology of dementias such as alzheimer disease. |
2021-05-10 |
2023-08-13 |
human |
Charuvaka Muvva, Natarajan Arul Murugan, Venkatesan Subramania. Assessment of Amyloid Forming Tendency of Peptide Sequences from Amyloid Beta and Tau Proteins Using Force-Field, Semi-Empirical, and Density Functional Theory Calculations. International journal of molecular sciences. vol 22. issue 6. 2021-05-10. PMID:33806726. |
in alzheimer's disease (ad), the extracellular aggregates originate from amyloid-β proteins, while the intracellular aggregates are formed from microtubule-binding tau proteins. |
2021-05-10 |
2023-08-13 |
Not clear |
Annie G Bryant, Miwei Hu, Becky C Carlyle, Steven E Arnold, Matthew P Frosch, Sudeshna Das, Bradley T Hyman, Rachel E Bennet. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in neurology. vol 11. 2021-05-08. PMID:33041998. |
cerebrovascular senescence is associated with tau pathology in alzheimer's disease. |
2021-05-08 |
2023-08-13 |
human |
Annie G Bryant, Miwei Hu, Becky C Carlyle, Steven E Arnold, Matthew P Frosch, Sudeshna Das, Bradley T Hyman, Rachel E Bennet. Cerebrovascular Senescence Is Associated With Tau Pathology in Alzheimer's Disease. Frontiers in neurology. vol 11. 2021-05-08. PMID:33041998. |
alzheimer's disease (ad) is associated with neuropathological changes, including aggregation of tau neurofibrillary tangles (nfts) and amyloid-beta plaques. |
2021-05-08 |
2023-08-13 |
human |
Claudia Cicognola, Tugce Munise Satir, Gunnar Brinkmalm, Irena Matečko-Burmann, Lotta Agholme, Petra Bergström, Bruno Becker, Henrik Zetterberg, Kaj Blennow, Kina Höglun. Tauopathy-Associated Tau Fragment Ending at Amino Acid 224 Is Generated by Calpain-2 Cleavage. Journal of Alzheimer's disease : JAD. vol 74. issue 4. 2021-05-07. PMID:32144989. |
tau aggregation in neurons and glial cells characterizes tauopathies as alzheimer's disease (ad), progressive supranuclear palsy (psp) and corticobasal degeneration (cbd). |
2021-05-07 |
2023-08-13 |
Not clear |
Andrew J Aschenbrenner, Brian A Gordon, Anne M Fagan, Suzanne E Schindler, David A Balota, John C Morris, Jason J Hassensta. Neurofilament Light Predicts Decline in Attention but Not Episodic Memory in Preclinical Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 74. issue 4. 2021-05-07. PMID:32144992. |
cerebrospinal fluid tau and neurofilament light (nfl) are two biomarkers of neurodegeneration in alzheimer's disease. |
2021-05-07 |
2023-08-13 |
Not clear |
Mario Hernandes-Alejandro, Sarita Montaño, Charles R Harrington, Claude M Wischik, Andrés Salas-Casas, Pedro Cortes-Reynosa, Eduardo Pérez Salazar, Javier Cazares-Apatiga, Ricardo Apatiga-Perez, Miguel Ángel Ontiveros Torres, George Perry, Mar Pacheco-Herrero, José Luna-Muño. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 76. issue 2. 2021-05-07. PMID:32538846. |
analysis of the relationship between metalloprotease-9 and tau protein in alzheimer's disease. |
2021-05-07 |
2023-08-13 |
Not clear |
Katelyn Cuttler, Monique J Bignoux, Tyrone C Otgaar, Stephanie Chigumba, Eloise Ferreira, Stefan F T Weis. LRP::FLAG Reduces Phosphorylated Tau Levels in Alzheimer's Disease Cell Culture Models. Journal of Alzheimer's disease : JAD. vol 76. issue 2. 2021-05-07. PMID:32568204. |
lrp::flag reduces phosphorylated tau levels in alzheimer's disease cell culture models. |
2021-05-07 |
2023-08-13 |
human |
K A Iteire, A T Sowole, B Ogunlad. Exposure to pyrethroids induces behavioral impairments, neurofibrillary tangles and tau pathology in Alzheimer's type neurodegeneration in adult Wistar rats. Drug and chemical toxicology. 2021-05-07. PMID:32907430. |
exposure to pyrethroids induces behavioral impairments, neurofibrillary tangles and tau pathology in alzheimer's type neurodegeneration in adult wistar rats. |
2021-05-07 |
2023-08-13 |
rat |
K A Iteire, A T Sowole, B Ogunlad. Exposure to pyrethroids induces behavioral impairments, neurofibrillary tangles and tau pathology in Alzheimer's type neurodegeneration in adult Wistar rats. Drug and chemical toxicology. 2021-05-07. PMID:32907430. |
this study investigated the exposure of pyrethroids in the development of alzheimer's type neurodegeneration by analyzing β- amyloid, tau and glial fibrillary acidic protein (gfap) in adult wistar rats. |
2021-05-07 |
2023-08-13 |
rat |
Bin Li, Pei-Jun Xie, Yan-Wei Hao, Yu Guo, Jun-Rong Yu, Dao-Yin Gong, Jing Guo, Jin-Hao Zeng, Yi Zhan. Yuan‑zhi‑san inhibits tau protein aggregation in an Aβ Molecular medicine reports. vol 23. issue 4. 2021-05-07. PMID:33604685. |
yuan‑zhi‑san inhibits tau protein aggregation in an aβ yuan‑zhi‑san (yzs) is a classic type of traditional chinese medicine, which has been reported to aid in the treatment of alzheimer's disease (ad). |
2021-05-07 |
2023-08-13 |
Not clear |
Tatsuhiro Terada, Joseph Therriault, Min Su Peter Kang, Melissa Savard, Tharick Ali Pascoal, Firoza Lussier, Cecile Tissot, Yi-Ting Wang, Andrea Benedet, Takashi Matsudaira, Tomoyasu Bunai, Tomokazu Obi, Hideo Tsukada, Yasuomi Ouchi, Pedro Rosa-Net. Mitochondrial complex I abnormalities is associated with tau and clinical symptoms in mild Alzheimer's disease. Molecular neurodegeneration. vol 16. issue 1. 2021-05-07. PMID:33902654. |
mitochondrial complex i abnormalities is associated with tau and clinical symptoms in mild alzheimer's disease. |
2021-05-07 |
2023-08-13 |
Not clear |