| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sheue-Er Wang, Chung-Hsin W. Tau phosphorylation and cochlear apoptosis cause hearing loss in 3×Tg-AD Mouse Model of Alzheimer's Disease. The Chinese journal of physiology. vol 64. issue 2. 2021-05-05. PMID:33938816. |
tau phosphorylation and cochlear apoptosis cause hearing loss in 3×tg-ad mouse model of alzheimer's disease. |
2021-05-05 |
2023-08-13 |
mouse |
| Pankaj Wadhwa, Priti Jain, Hemant R Jadha. Glycogen Synthase Kinase 3 (GSK3): Its Role and Inhibitors. Current topics in medicinal chemistry. vol 20. issue 17. 2021-05-04. PMID:32416693. |
however, gsk3β is highly expressed in different areas of the brain and has been implicated in alzheimer's disease as it is involved in tau phosphorylation. |
2021-05-04 |
2023-08-13 |
Not clear |
| Samantha De La-Rocque, Edoardo Moretto, Ioana Butnaru, Giampietro Schiav. Knockin' on heaven's door: Molecular mechanisms of neuronal tau uptake. Journal of neurochemistry. vol 156. issue 5. 2021-05-04. PMID:32770783. |
since aggregates of the microtubule-binding protein tau were found to be the main component of neurofibrillary tangles more than 30 years ago, their contribution to neurodegeneration in alzheimer's disease (ad) and tauopathies has become well established. |
2021-05-04 |
2023-08-13 |
Not clear |
| Roger J Mullins, Thomas C Diehl, Chee W Chia, Dimitrios Kapogianni. Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease. Frontiers in aging neuroscience. vol 9. 2021-05-03. PMID:28515688. |
insulin resistance as a link between amyloid-beta and tau pathologies in alzheimer's disease. |
2021-05-03 |
2023-08-13 |
human |
| Lih-Fen Lue, Marwan N Sabbagh, Ming-Jang Chiu, Naomi Jing, Noelle L Snyder, Christopher Schmitz, Andre Guerra, Christine M Belden, Ta-Fu Chen, Che-Chuan Yang, Shieh-Yueh Yang, Douglas G Walker, Kewei Chen, Eric M Reima. Plasma Levels of Aβ42 and Tau Identified Probable Alzheimer's Dementia: Findings in Two Cohorts. Frontiers in aging neuroscience. vol 9. 2021-05-03. PMID:28790911. |
plasma levels of aβ42 and tau identified probable alzheimer's dementia: findings in two cohorts. |
2021-05-03 |
2023-08-13 |
human |
| Lih-Fen Lue, Marwan N Sabbagh, Ming-Jang Chiu, Naomi Jing, Noelle L Snyder, Christopher Schmitz, Andre Guerra, Christine M Belden, Ta-Fu Chen, Che-Chuan Yang, Shieh-Yueh Yang, Douglas G Walker, Kewei Chen, Eric M Reima. Plasma Levels of Aβ42 and Tau Identified Probable Alzheimer's Dementia: Findings in Two Cohorts. Frontiers in aging neuroscience. vol 9. 2021-05-03. PMID:28790911. |
the utility of plasma amyloid beta (aβ) and tau levels for the clinical diagnosis of alzheimer's disease (ad) dementia has been controversial. |
2021-05-03 |
2023-08-13 |
human |
| Bernard J Hanseeuw, Rebecca A Betensky, Heidi I L Jacobs, Aaron P Schultz, Jorge Sepulcre, J Alex Becker, Danielle M Orozco Cosio, Michelle Farrell, Yakeel T Quiroz, Elizabeth C Mormino, Rachel F Buckley, Kathryn V Papp, Rebecca A Amariglio, Ilse Dewachter, Adrian Ivanoiu, Willem Huijbers, Trey Hedden, Gad A Marshall, Jasmeer P Chhatwal, Dorene M Rentz, Reisa A Sperling, Keith Johnso. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. JAMA neurology. vol 76. issue 8. 2021-05-03. PMID:31157827. |
association of amyloid and tau with cognition in preclinical alzheimer disease: a longitudinal study. |
2021-05-03 |
2023-08-13 |
Not clear |
| Bernard J Hanseeuw, Rebecca A Betensky, Heidi I L Jacobs, Aaron P Schultz, Jorge Sepulcre, J Alex Becker, Danielle M Orozco Cosio, Michelle Farrell, Yakeel T Quiroz, Elizabeth C Mormino, Rachel F Buckley, Kathryn V Papp, Rebecca A Amariglio, Ilse Dewachter, Adrian Ivanoiu, Willem Huijbers, Trey Hedden, Gad A Marshall, Jasmeer P Chhatwal, Dorene M Rentz, Reisa A Sperling, Keith Johnso. Association of Amyloid and Tau With Cognition in Preclinical Alzheimer Disease: A Longitudinal Study. JAMA neurology. vol 76. issue 8. 2021-05-03. PMID:31157827. |
positron emission tomography (pet) imaging now allows in vivo visualization of both neuropathologic hallmarks of alzheimer disease (ad): amyloid-β (aβ) plaques and tau neurofibrillary tangles. |
2021-05-03 |
2023-08-13 |
Not clear |
| Shweta Kishor Sonawane, Hariharakrishnan Chidambaram, Debjyoti Boral, Nalini Vijay Gorantla, Abhishek Ankur Balmik, Abha Dangi, Sureshkumar Ramasamy, Udaya Kiran Marelli, Subashchandrabose Chinnathamb. EGCG impedes human Tau aggregation and interacts with Tau. Scientific reports. vol 10. issue 1. 2021-05-03. PMID:32724104. |
tau aggregation and accumulation is a key event in the pathogenesis of alzheimer's disease. |
2021-05-03 |
2023-08-13 |
human |
| Lisha Wang, Bharti, Rajnish Kumar, Pavel F Pavlov, Bengt Winbla. Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance. European journal of medicinal chemistry. vol 209. 2021-05-03. PMID:33139110. |
alzheimer's disease (ad) is the most common form of dementia characterized by presence of extracellular amyloid plaques and intracellular neurofibrillary tangles composed of tau protein. |
2021-05-03 |
2023-08-13 |
Not clear |
| Yinyin Tan, Yanqun Zheng, Daiwen Xu, Zhanfang Sun, Huan Yang, Qingqing Yi. Galectin-3: a key player in microglia-mediated neuroinflammation and Alzheimer's disease. Cell & bioscience. vol 11. issue 1. 2021-05-02. PMID:33906678. |
alzheimer's disease (ad) is the most common cause of dementia and is characterized by the deposition of extracellular aggregates of amyloid-β (aβ), the formation of intraneuronal tau neurofibrillary tangles and microglial activation-mediated neuroinflammation. |
2021-05-02 |
2023-08-13 |
human |
| Monika Arbaciauskaite, Yu Lei, Yong Ku Ch. High-specificity antibodies and detection methods for quantifying phosphorylated tau from clinical samples. Antibody therapeutics. vol 4. issue 1. 2021-05-02. PMID:33928234. |
the ability to measure total and phosphorylated tau levels in clinical samples is transforming the detection of alzheimer's disease (ad) and other neurodegenerative diseases. |
2021-05-02 |
2023-08-13 |
Not clear |
| Islauddin Khan, Kumari Preeti, Valencia Fernandes, Dharmendra Kumar Khatri, Shashi Bala Sing. Role of MicroRNAs, Aptamers in Neuroinflammation and Neurodegenerative Disorders. Cellular and molecular neurobiology. 2021-05-02. PMID:33934227. |
ndds like alzheimer's disease, parkinson's disease, huntington's disease, multiple sclerosis, prion disease, and others are characterized by deposition of misfolded protein such as amyloid-ß, tau, α-synuclein, huntingtin and prion proteins. |
2021-05-02 |
2023-08-13 |
human |
| Edward S Wickstead, Murray A Irving, Stephen J Getting, Simon McArthu. Exploiting formyl peptide receptor 2 to promote microglial resolution: a new approach to Alzheimer's disease treatment. The FEBS journal. 2021-05-01. PMID:33811735. |
alzheimer's disease pathology has long been considered in terms of accumulation of amyloid beta and hyperphosphorylated tau, but the importance of neuroinflammation in driving disease has taken greater precedence over the last 15-20 years. |
2021-05-01 |
2023-08-13 |
human |
| Münteha Nur Sonuç Karaboga, Mustafa Kemal Sezgintür. Analysis of Tau-441 protein in clinical samples using rGO/AuNP nanocomposite-supported disposable impedimetric neuro-biosensing platform: Towards Alzheimer's disease detection. Talanta. vol 219. 2021-04-30. PMID:32887148. |
changes in isoforms of tau protein, which are critical for microtubule functioning, are accepted as being responsible for diseases characterized by dementia, in particular alzheimer's disease (ad). |
2021-04-30 |
2023-08-13 |
Not clear |
| Jochen Hammes, Gérard N Bischof, Karl P Bohn, Özgür Onur, Anja Schneider, Klaus Fliessbach, Merle C Hönig, Frank Jessen, Bernd Neumaier, Alexander Drzezga, Thilo van Eimere. One-Stop Shop: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 62. issue 2. 2021-04-29. PMID:32620704. |
one-stop shop: tau protein aggregations are a hallmark of amyloid-associated alzheimer disease and some forms of non-amyloid-associated frontotemporal lobar degeneration. |
2021-04-29 |
2023-08-13 |
Not clear |
| Yun Wei, Meixia Liu, Dongxin Wan. The propagation mechanisms of extracellular tau in Alzheimer's disease. Journal of neurology. 2021-04-29. PMID:33913022. |
the propagation mechanisms of extracellular tau in alzheimer's disease. |
2021-04-29 |
2023-08-13 |
Not clear |
| Yun Wei, Meixia Liu, Dongxin Wan. The propagation mechanisms of extracellular tau in Alzheimer's disease. Journal of neurology. 2021-04-29. PMID:33913022. |
the abnormal intracellular aggregation of tau has been strongly associated with alzheimer's disease (ad). |
2021-04-29 |
2023-08-13 |
Not clear |
| Samuel Iddi, Dan Li, Paul S Aisen, Michael S Rafii, Wesley K Thompson, Michael C Donohu. Predicting the course of Alzheimer's progression. Brain informatics. vol 6. issue 1. 2021-04-28. PMID:31254120. |
alzheimer's disease is the most common neurodegenerative disease and is characterized by the accumulation of amyloid-beta peptides leading to the formation of plaques and tau protein tangles in brain. |
2021-04-28 |
2023-08-13 |
Not clear |
| Philip S Insel, Elizabeth C Mormino, Paul S Aisen, Wesley K Thompson, Michael C Donohu. Neuroanatomical spread of amyloid β and tau in Alzheimer's disease: implications for primary prevention. Brain communications. vol 2. issue 1. 2021-04-28. PMID:32140682. |
neuroanatomical spread of amyloid β and tau in alzheimer's disease: implications for primary prevention. |
2021-04-28 |
2023-08-13 |
human |