All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Suzanne E Hickman, Elizabeth K Allison, Uwanda Coleman, Nathan D Kingery-Gallagher, Joseph El Khour. Heterozygous CX3CR1 Deficiency in Microglia Restores Neuronal β-Amyloid Clearance Pathways and Slows Progression of Alzheimer's Like-Disease in PS1-APP Mice. Frontiers in immunology. vol 10. 2020-11-10. PMID:31849963. full deletion of cx3cr1 in mouse models of alzheimer's disease have opposing effects on amyloid-β and tau pathologies raising concerns about the benefits of targeting cx3cr1 for treatment of this disease. 2020-11-10 2023-08-13 mouse
Andrew R Mendelsohn, James W Larric. The Danger of Being Too Sympathetic: Norepinephrine in Alzheimer's Disease and Graying of Hair. Rejuvenation research. vol 23. issue 1. 2020-11-10. PMID:31989871. first, low nanomolar concentrations of alzheimer's disease (ad)-associated aβ42-amyloid oligomers alter signaling by sns neurotransmitter norepinephrine (ne) to sufficiently activate kinase gsk3β to hyperphosphorylate tau, a key mediator of neurotoxicity in ad. 2020-11-10 2023-08-13 Not clear
George Tetz, Michelle Pinho, Sandra Pritzkow, Nicolas Mendez, Claudio Soto, Victor Tet. Bacterial DNA promotes Tau aggregation. Scientific reports. vol 10. issue 1. 2020-11-10. PMID:32047247. a hallmark feature of alzheimer's disease (ad) and other tauopathies is the misfolding, aggregation and cerebral accumulation of tau deposits. 2020-11-10 2023-08-13 Not clear
Bahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, Alyssa Coyne, Julia Schiantarelli, Yari Carlomagno, Casey Cook, Sean J Miller, Simon Dujardin, Ana S Amaral, Jonathan C Grima, Rachel E Bennett, Katharina Tepper, Michael DeTure, Charles R Vanderburg, Bianca T Corjuc, Sarah L DeVos, Jose Antonio Gonzalez, Jeannie Chew, Svetlana Vidensky, Fred H Gage, Jerome Mertens, Juan Troncoso, Eckhard Mandelkow, Xavier Salvatella, Roderick Y H Lim, Leonard Petrucelli, Susanne Wegmann, Jeffrey D Rothstein, Bradley T Hyma. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. vol 101. issue 2. 2020-11-09. PMID:30653936. tau protein disrupts nucleocytoplasmic transport in alzheimer's disease. 2020-11-09 2023-08-13 Not clear
Rashmi Das, Abhishek Ankur Balmik, Subashchandrabose Chinnathamb. Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia. Journal of neuroinflammation. vol 17. issue 1. 2020-11-09. PMID:31915009. alzheimer's disease is associated with the accumulation of intracellular tau tangles within neurons and extracellular amyloid-β plaques in the brain parenchyma, which altogether results in synaptic loss and neurodegeneration. 2020-11-09 2023-08-13 Not clear
Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. proteomic and genomic changes in tau protein, which are associated with alzheimer's disease after ischemia-reperfusion brain injury. 2020-11-09 2023-08-13 Not clear
Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. recent evidence suggests that transient ischemia of the brain with reperfusion in humans and animals is associated with the neuronal accumulation of neurotoxic molecules associated with alzheimer's disease, such as all parts of the amyloid protein precursor and modified tau protein. 2020-11-09 2023-08-13 Not clear
Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. pathological changes in the amyloid protein precursor and tau protein at the protein and gene level due to ischemia may lead to dementia of the alzheimer's disease type after ischemic brain injury. 2020-11-09 2023-08-13 Not clear
Marzena Ułamek-Kozioł, Stanisław Jerzy Czuczwar, Sławomir Januszewski, Ryszard Plut. Proteomic and Genomic Changes in Tau Protein, Which Are Associated with Alzheimer's Disease after Ischemia-Reperfusion Brain Injury. International journal of molecular sciences. vol 21. issue 3. 2020-11-09. PMID:32019137. finally we present the positive correlation between tau protein dysfunction and the development of sporadic alzheimer's disease type of neurodegeneration. 2020-11-09 2023-08-13 Not clear
Jung-Lung Hsu, Kun-Ju Lin, Ing-Tsung Hsiao, Kuo-Lun Huang, Chi-Hung Liu, Hsiu-Chuan Wu, Yi-Ching Weng, Chu-Yun Huang, Chiung-Chih Chang, Tzu-Chen Yen, Makoto Higuchi, Ming-Kuei Jang, Chin-Chang Huan. The Imaging Features and Clinical Associations of a Novel Tau PET Tracer-18F-APN1607 in Alzheimer Disease. Clinical nuclear medicine. vol 45. issue 10. 2020-11-09. PMID:32701794. the imaging features and clinical associations of a novel tau pet tracer-18f-apn1607 in alzheimer disease. 2020-11-09 2023-08-13 Not clear
Jung-Lung Hsu, Kun-Ju Lin, Ing-Tsung Hsiao, Kuo-Lun Huang, Chi-Hung Liu, Hsiu-Chuan Wu, Yi-Ching Weng, Chu-Yun Huang, Chiung-Chih Chang, Tzu-Chen Yen, Makoto Higuchi, Ming-Kuei Jang, Chin-Chang Huan. The Imaging Features and Clinical Associations of a Novel Tau PET Tracer-18F-APN1607 in Alzheimer Disease. Clinical nuclear medicine. vol 45. issue 10. 2020-11-09. PMID:32701794. in vivo tau pet imaging could help clarify the spatial distribution of tau deposition in alzheimer disease (ad) and aid in the differential diagnosis of tauopathies. 2020-11-09 2023-08-13 Not clear
Christian Tackenberg, Luka Kulic, Roger M Nitsc. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. PloS one. vol 15. issue 9. 2020-11-09. PMID:32966331. familial alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system. 2020-11-09 2023-08-13 mouse
Lauren K Rudenko, Horst Wallrabe, Ammasi Periasamy, Karsten H Siller, Zdenek Svindrych, Matthew E Seward, Merci N Best, George S Bloo. Intraneuronal Tau Misfolding Induced by Extracellular Amyloid-β Oligomers. Journal of Alzheimer's disease : JAD. vol 71. issue 4. 2020-11-06. PMID:31524157. abnormal folding and aggregation of the microtubule-associated protein, tau, is a hallmark of several neurodegenerative disorders, including alzheimer's disease (ad). 2020-11-06 2023-08-13 mouse
Carol J Huseby, Claire N Hoffman, Grace L Cooper, Jean-Christophe Cocuron, Ana P Alonso, Stefani N Thomas, Austin J Yang, Jeff Kure. Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31450505. quantification of tau protein lysine methylation in aging and alzheimer's disease. 2020-11-05 2023-08-13 human
Arnaud Charil, Sergey Shcherbinin, Sudeepti Southekal, Michael D Devous, Mark Mintun, Melissa E Murray, Bradley B Miller, Adam J Schwar. Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476153. tau subtypes of alzheimer's disease determined in vivo using flortaucipir pet imaging. 2020-11-05 2023-08-13 human
Eglė Jakubauskienė, Laurynas Vilys, Inga Pečiulienė, Arvydas Kanopk. The role of hypoxia on Alzheimer's disease-related APP and Tau mRNA formation. Gene. vol 766. 2020-11-05. PMID:32941952. the role of hypoxia on alzheimer's disease-related app and tau mrna formation. 2020-11-05 2023-08-13 Not clear
Eglė Jakubauskienė, Laurynas Vilys, Inga Pečiulienė, Arvydas Kanopk. The role of hypoxia on Alzheimer's disease-related APP and Tau mRNA formation. Gene. vol 766. 2020-11-05. PMID:32941952. in the presented study, we have examined the influence of cellular hypoxia on mrna splice variant formation from alzheimer's disease-related tau and app genes in brain cells. 2020-11-05 2023-08-13 Not clear
Ram Reddy Chandupatla, Andrew Flatley, Regina Feederle, Eva-Maria Mandelkow, Senthilvelrajan Kaniyappa. Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes. Alzheimer's & dementia (New York, N. Y.). vol 6. issue 1. 2020-11-05. PMID:33145390. tau, a natively unfolded soluble protein, forms abnormal oligomers and insoluble filaments in several neurodegenerative diseases, including alzheimer disease (ad). 2020-11-05 2023-08-13 Not clear
Paola Flores-Rodríguez, Charles R Harrington, Claude M Wischik, Vanessa Ibarra-Bracamontes, Natanael Zarco, Araceli Navarrete, Alejandra Martínez-Maldonado, Parménides Guadarrama-Ortíz, Ignacio Villanueva-Fierro, Miguel Angel Ontiveros-Torres, George Perry, Alejandra D Alonso, Benjamin Floran-Garduño, José Segovia, José Luna-Muño. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. Journal of Alzheimer's disease : JAD. vol 71. issue 2. 2020-11-04. PMID:31424392. in alzheimer's disease, tau protein is the major constituent of the paired helical filament, and it undergoes post-translational modifications including hyperphosphorylation and truncation. 2020-11-04 2023-08-13 human
Paola Flores-Rodríguez, Charles R Harrington, Claude M Wischik, Vanessa Ibarra-Bracamontes, Natanael Zarco, Araceli Navarrete, Alejandra Martínez-Maldonado, Parménides Guadarrama-Ortíz, Ignacio Villanueva-Fierro, Miguel Angel Ontiveros-Torres, George Perry, Alejandra D Alonso, Benjamin Floran-Garduño, José Segovia, José Luna-Muño. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. Journal of Alzheimer's disease : JAD. vol 71. issue 2. 2020-11-04. PMID:31424392. whether other functions of tau protein are involved in alzheimer's disease is less clear. 2020-11-04 2023-08-13 human