All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Jenna N Adams, Samuel N Lockhart, Lexin Li, William J Jagus. Relationships Between Tau and Glucose Metabolism Reflect Alzheimer's Disease Pathology in Cognitively Normal Older Adults. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 5. 2020-06-17. PMID:29912295. relationships between tau and glucose metabolism reflect alzheimer's disease pathology in cognitively normal older adults. 2020-06-17 2023-08-13 human
Jenna N Adams, Samuel N Lockhart, Lexin Li, William J Jagus. Relationships Between Tau and Glucose Metabolism Reflect Alzheimer's Disease Pathology in Cognitively Normal Older Adults. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 5. 2020-06-17. PMID:29912295. tau is associated with hypometabolism in patients with alzheimer's disease. 2020-06-17 2023-08-13 human
Amber Nolan, Elisa De Paula Franca Resende, Cathrine Petersen, Kyra Neylan, Salvatore Spina, Eric Huang, William Seeley, Zachary Miller, Lea T Grinber. Astrocytic Tau Deposition Is Frequent in Typical and Atypical Alzheimer Disease Presentations. Journal of neuropathology and experimental neurology. vol 78. issue 12. 2020-06-17. PMID:31626288. astrocytic tau deposition is frequent in typical and atypical alzheimer disease presentations. 2020-06-17 2023-08-13 Not clear
Joana R F Santos, Chris Bauer, Johannes Schuchhardt, Dirk Wedekind, Katharina Waniek, Ingolf Lachmann, Jens Wiltfang, Jonathan Vogelgsan. Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 3. 2020-06-16. PMID:30767082. validation of a prototype tau thr231 phosphorylation csf elisa as a potential biomarker for alzheimer's disease. 2020-06-16 2023-08-13 Not clear
Joana R F Santos, Chris Bauer, Johannes Schuchhardt, Dirk Wedekind, Katharina Waniek, Ingolf Lachmann, Jens Wiltfang, Jonathan Vogelgsan. Validation of a prototype tau Thr231 phosphorylation CSF ELISA as a potential biomarker for Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 3. 2020-06-16. PMID:30767082. alzheimer's disease (ad) is a progressive neurodegenerative disorder characterized by the presence of extracellular amyloid plaques (senile plaques) and intracellular neurofibrillary tangles formed by hyperphosphorylated tau protein. 2020-06-16 2023-08-13 Not clear
Dibson D Gondim, Adrian Oblak, Jill R Murrell, Rose Richardson, Francine Epperson, Owen A Ross, Bernardino Ghett. Diffuse Lewy Body Disease and Alzheimer Disease: Neuropathologic Phenotype Associated With the PSEN1 p.A396T Mutation. Journal of neuropathology and experimental neurology. vol 78. issue 7. 2020-06-16. PMID:31165862. in sporadic and dominantly inherited alzheimer disease (ad), aggregation of both tau and α-synuclein may occur in neurons. 2020-06-16 2023-08-13 Not clear
Jinny Claire Lee, Soo Jung Kim, Seungpyo Hong, YoungSoo Ki. Diagnosis of Alzheimer's disease utilizing amyloid and tau as fluid biomarkers. Experimental & molecular medicine. vol 51. issue 5. 2020-06-15. PMID:31073121. diagnosis of alzheimer's disease utilizing amyloid and tau as fluid biomarkers. 2020-06-15 2023-08-13 Not clear
Kaixiang Zhou, Chang Yuan, Bin Dai, Kan Wang, Yimin Chen, Denglei Ma, Jiapei Dai, Yi Liang, Hongwei Tan, Mengchao Cu. Environment-Sensitive Near-Infrared Probe for Fluorescent Discrimination of Aβ and Tau Fibrils in AD Brain. Journal of medicinal chemistry. vol 62. issue 14. 2020-06-15. PMID:31274302. the early noninvasive diagnosis of alzheimer's disease targeted β-amyloid (aβ) plaques or tau tangles is a major challenge because of the coshared β-sheet structure of the target. 2020-06-15 2023-08-13 Not clear
Clifford R Jack, Heather J Wiste, Hugo Botha, Stephen D Weigand, Terry M Therneau, David S Knopman, Jonathan Graff-Radford, David T Jones, Tanis J Ferman, Bradley F Boeve, Kejal Kantarci, Val J Lowe, Prashanthi Vemuri, Michelle M Mielke, Julie A Fields, Mary M Machulda, Christopher G Schwarz, Matthew L Senjem, Jeffrey L Gunter, Ronald C Peterse. The bivariate distribution of amyloid-β and tau: relationship with established neurocognitive clinical syndromes. Brain : a journal of neurology. vol 142. issue 10. 2020-06-15. PMID:31501889. we studied 1343 participants who had amyloid pet and tau pet from 2 april 2015 to 3 may 2019, and met criteria for membership in one of five clinical diagnostic groups: cognitively unimpaired, mild cognitive impairment, frontotemporal dementia, probable dementia with lewy bodies, and alzheimer clinical syndrome. 2020-06-15 2023-08-13 human
Francesco Panza, Madia Lozupone, Vincenzo Solfrizzi, Mark Watling, Bruno P Imbimb. Time to test antibacterial therapy in Alzheimer's disease. Brain : a journal of neurology. vol 142. issue 10. 2020-06-15. PMID:31532495. alzheimer's disease is associated with cerebral accumulation of amyloid-β peptide and hyperphosphorylated tau. 2020-06-15 2023-08-13 human
Daniel Fleck, Lilian Phu, Erik Verschueren, Trent Hinkle, Mike Reichelt, Tushar Bhangale, Benjamin Haley, Yuanyuan Wang, Robert Graham, Donald S Kirkpatrick, Morgan Sheng, Baris Bingo. PTCD1 Is Required for Mitochondrial Oxidative-Phosphorylation: Possible Genetic Association with Alzheimer's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 39. issue 24. 2020-06-12. PMID:30948477. in addition to amyloid-β plaques and tau tangles, mitochondrial dysfunction is implicated in the pathology of alzheimer's disease (ad). 2020-06-12 2023-08-13 human
Mari Nakamura, Seiji Shiozawa, Daisuke Tsuboi, Mutsuki Amano, Hirotaka Watanabe, Sumihiro Maeda, Taeko Kimura, Sho Yoshimatsu, Fumihiko Kisa, Celeste M Karch, Tomohiro Miyasaka, Akihiko Takashima, Naruhiko Sahara, Shin-Ichi Hisanaga, Takeshi Ikeuchi, Kozo Kaibuchi, Hideyuki Okan. Pathological Progression Induced by the Frontotemporal Dementia-Associated R406W Tau Mutation in Patient-Derived iPSCs. Stem cell reports. vol 13. issue 4. 2020-06-10. PMID:31543469. the r406w tau mutation is a unique missense mutation whose patients have been reported to exhibit alzheimer's disease (ad)-like phenotypes rather than the more typical ftd phenotypes. 2020-06-10 2023-08-13 Not clear
Allison Leso, Syed W Bihaqi, Anwar Masoud, Joanna K Chang, Asma Lahouel, Nasser Zawi. Loss in efficacy measures of tolfenamic acid in a tau knock-out model: Relevance to Alzheimer's disease. Experimental biology and medicine (Maywood, N.J.). vol 244. issue 13. 2020-06-09. PMID:31450960. loss in efficacy measures of tolfenamic acid in a tau knock-out model: relevance to alzheimer's disease. 2020-06-09 2023-08-13 Not clear
Deepa Ajit, Hanna Trzeciakiewicz, Jui-Heng Tseng, Connor M Wander, Youjun Chen, Aditi Ajit, Diamond P King, Todd J Cohe. A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation. The Journal of biological chemistry. vol 294. issue 45. 2020-06-08. PMID:31543505. abnormal intracellular accumulation of aggregated tau is a hallmark feature of alzheimer's disease and other tauopathies. 2020-06-08 2023-08-13 mouse
Tessa Sinnige, Anan Yu, Richard I Morimot. Challenging Proteostasis: Role of the Chaperone Network to Control Aggregation-Prone Proteins in Human Disease. Advances in experimental medicine and biology. vol 1243. 2020-06-08. PMID:32297211. for alzheimer's, parkinson's, huntington's diseases and als, multiple classes of molecular chaperones interact with the highly aggregation-prone proteins amyloid-β, tau, α-synuclein, huntingtin and sod1 to influence the course of proteotoxicity associated with these neurodegenerative diseases. 2020-06-08 2023-08-13 human
Sen Li, Furong Xian, Xiao Guan, Kai Huang, Wenwen Yu, Dandan Li. Neural Protective Effects of Millet and Millet Polyphenols on High-Fat Diet-Induced Oxidative Stress in the Brain. Plant foods for human nutrition (Dordrecht, Netherlands). vol 75. issue 2. 2020-06-04. PMID:32078112. our results suggested that the intake of millet could alleviate oxidative stress in the hippocampus and downregulate the expression of the alzheimer's disease (ad)-related genes amyloid precursor protein (app), tau, and γ-secretase. 2020-06-04 2023-08-13 rat
Ying Chen, Yuling Chen, Yubin Liang, Hongda Chen, Xiaoying Ji, Min Huan. Berberine mitigates cognitive decline in an Alzheimer's Disease Mouse Model by targeting both tau hyperphosphorylation and autophagic clearance. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 121. 2020-06-02. PMID:31810131. berberine mitigates cognitive decline in an alzheimer's disease mouse model by targeting both tau hyperphosphorylation and autophagic clearance. 2020-06-02 2023-08-13 mouse
G C Román, R E Jackson, R Gadhia, A N Román, J Rei. Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease. Revue neurologique. vol 175. issue 10. 2020-06-01. PMID:31521398. polyphenols from fruits and vegetables modulate tau hyperphosphorylation and beta amyloid aggregation in animal models of alzheimer disease. 2020-06-01 2023-08-13 Not clear
Johannes Levi. Parkinsonism in genetic and sporadic Alzheimer's disease. International review of neurobiology. vol 149. 2020-06-01. PMID:31779814. alzheimer disease (ad) is a neurodegenerative disease characterized by deposition of pathologically aggregated amyloid-β in the extracellular space and pathologically aggregated tau protein in the intracellular space. 2020-06-01 2023-08-13 Not clear
Jiwana Sherin Midani-Kurçak, Maja Dinekov, Behrus Puladi, Thomas Arzberger, Christoph Köhle. Effect of tau-pathology on charged multivesicular body protein 2b (CHMP2B). Brain research. vol 1706. 2020-05-29. PMID:30414727. we analyzed immunolabeled brain sections from tau-transgenic mice, app-transgenic mice, non-transgenic mice, and human hippocampi to investigate the relation between chmp2b and tau and plaque pathology that are major histopathological features of alzheimer's disease. 2020-05-29 2023-08-13 mouse