All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Niklas Mattsson, Rik Ossenkoppele, Ruben Smith, Olof Strandberg, Tomas Ohlsson, Jonas Jögi, Sebastian Palmqvist, Erik Stomrud, Oskar Hansso. Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-06. PMID:30086796. greater tau load and reduced cortical thickness in apoe ε4-negative alzheimer's disease: a cohort study. 2019-08-06 2023-08-13 Not clear
Niklas Mattsson, Rik Ossenkoppele, Ruben Smith, Olof Strandberg, Tomas Ohlsson, Jonas Jögi, Sebastian Palmqvist, Erik Stomrud, Oskar Hansso. Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-06. PMID:30086796. alzheimer's disease is characterized by aggregated β-amyloid and tau proteins, but the clinical presentations and patterns of brain atrophy vary substantially. 2019-08-06 2023-08-13 Not clear
Niklas Mattsson, Rik Ossenkoppele, Ruben Smith, Olof Strandberg, Tomas Ohlsson, Jonas Jögi, Sebastian Palmqvist, Erik Stomrud, Oskar Hansso. Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer's disease: a cohort study. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-06. PMID:30086796. the objective of this preliminary study was therefore to test if tau load and brain structure differ by apoe ε4 in alzheimer's disease. 2019-08-06 2023-08-13 Not clear
David C Schöndorf, Myriam Elschami, Maximilian Schieck, Ebru Ercan-Herbst, Christian Weber, Yasmin Riesinger, Sara Kalman, Doris Steinemann, Dagmar E Ehrnhoefe. Generation of an induced pluripotent stem cell cohort suitable to investigate sporadic Alzheimer's Disease. Stem cell research. vol 34. 2019-08-06. PMID:30611016. alzheimer's disease (ad) is the major cause of dementia in the elderly, and cortical neurons differentiated from patient-derived induced pluripotent stem cells (ipscs) can recapitulate disease phenotypes such as tau phosphorylation or amyloid beta (aß) deposition. 2019-08-06 2023-08-13 Not clear
Junjie Hu, Yang Yang, Minli Wang, Yi Yao, Yanmin Chang, Quanwei He, Rong Ma, Gang L. Complement C3a receptor antagonist attenuates tau hyperphosphorylation via glycogen synthase kinase 3β signaling pathways. European journal of pharmacology. vol 850. 2019-08-06. PMID:30771350. neurofibrillary tangles aggregated from hyperphosphorylated tau protein are the main pathological feature of alzheimer's disease (ad). 2019-08-06 2023-08-13 Not clear
Mei Ji, Xi-Xiu Xie, Dong-Qun Liu, Xiao-Lin Yu, Yue Zhang, Ling-Xiao Zhang, Shao-Wei Wang, Ya-Ru Huang, Rui-Tian Li. Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-02. PMID:29914543. hepatitis b core vlp-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in tau.p301s mouse model of alzheimer's disease and frontotemporal dementia. 2019-08-02 2023-08-13 mouse
Mei Ji, Xi-Xiu Xie, Dong-Qun Liu, Xiao-Lin Yu, Yue Zhang, Ling-Xiao Zhang, Shao-Wei Wang, Ya-Ru Huang, Rui-Tian Li. Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-02. PMID:29914543. truncated mis-disordered tau protein plays an important role in the pathogenesis of alzheimer's disease (ad) and frontotemporal dementia (ftd). 2019-08-02 2023-08-13 mouse
Krystal Herline, Frances Prelli, Pankaj Mehta, Claire MacMurray, Fernando Goñi, Thomas Wisniewsk. Immunotherapy to improve cognition and reduce pathological species in an Alzheimer's disease mouse model. Alzheimer's research & therapy. vol 10. issue 1. 2019-08-02. PMID:29914551. alzheimer's disease (ad) is characterized by physiologically endogenous proteins amyloid beta (aβ) and tau undergoing a conformational change and accumulating as soluble oligomers and insoluble aggregates. 2019-08-02 2023-08-13 mouse
Md Sahab Uddin, Md Tanvir Kabir, Abdullah Al Mamun, Mohamed M Abdel-Daim, George E Barreto, Ghulam Md Ashra. APOE and Alzheimer's Disease: Evidence Mounts that Targeting APOE4 may Combat Alzheimer's Pathogenesis. Molecular neurobiology. vol 56. issue 4. 2019-08-02. PMID:30032423. alzheimer's disease (ad) is an immutable neurodegenerative disease featured by the two hallmark brain pathologies that are the extracellular amyloid ß (aß) and intraneuronal tau protein. 2019-08-02 2023-08-13 Not clear
Bahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, Alyssa Coyne, Julia Schiantarelli, Yari Carlomagno, Casey Cook, Sean J Miller, Simon Dujardin, Ana S Amaral, Jonathan C Grima, Rachel E Bennett, Katharina Tepper, Michael DeTure, Charles R Vanderburg, Bianca T Corjuc, Sarah L DeVos, Jose Antonio Gonzalez, Jeannie Chew, Svetlana Vidensky, Fred H Gage, Jerome Mertens, Juan Troncoso, Eckhard Mandelkow, Xavier Salvatella, Roderick Y H Lim, Leonard Petrucelli, Susanne Wegmann, Jeffrey D Rothstein, Bradley T Hyma. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. vol 99. issue 5. 2019-08-01. PMID:30189209. tau protein disrupts nucleocytoplasmic transport in alzheimer's disease. 2019-08-01 2023-08-13 mouse
Bahareh Eftekharzadeh, J Gavin Daigle, Larisa E Kapinos, Alyssa Coyne, Julia Schiantarelli, Yari Carlomagno, Casey Cook, Sean J Miller, Simon Dujardin, Ana S Amaral, Jonathan C Grima, Rachel E Bennett, Katharina Tepper, Michael DeTure, Charles R Vanderburg, Bianca T Corjuc, Sarah L DeVos, Jose Antonio Gonzalez, Jeannie Chew, Svetlana Vidensky, Fred H Gage, Jerome Mertens, Juan Troncoso, Eckhard Mandelkow, Xavier Salvatella, Roderick Y H Lim, Leonard Petrucelli, Susanne Wegmann, Jeffrey D Rothstein, Bradley T Hyma. Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer's Disease. Neuron. vol 99. issue 5. 2019-08-01. PMID:30189209. tau is the major constituent of neurofibrillary tangles in alzheimer's disease (ad), but the mechanism underlying tau-associated neural damage remains unclear. 2019-08-01 2023-08-13 mouse
Jangampalli Adi Pradeepkiran, Arubala P Reddy, P Hemachandra Redd. Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer's disease. Drug discovery today. vol 24. issue 2. 2019-07-31. PMID:30453058. pharmacophore-based models for therapeutic drugs against phosphorylated tau in alzheimer's disease. 2019-07-31 2023-08-13 Not clear
Jangampalli Adi Pradeepkiran, Arubala P Reddy, P Hemachandra Redd. Pharmacophore-based models for therapeutic drugs against phosphorylated tau in Alzheimer's disease. Drug discovery today. vol 24. issue 2. 2019-07-31. PMID:30453058. phosphorylated tau (p-tau) has received much attention in the field of alzheimer's disease (ad), as a potential therapeutic target owing to its involvement with synaptic damage and neuronal dysfunction. 2019-07-31 2023-08-13 Not clear
Antoine Leuzy, Elena Rodriguez-Vieitez, Laure Saint-Aubert, Konstantinos Chiotis, Ove Almkvist, Irina Savitcheva, My Jonasson, Mark Lubberink, Anders Wall, Gunnar Antoni, Agneta Nordber. Longitudinal uncoupling of cerebral perfusion, glucose metabolism, and tau deposition in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 5. 2019-07-30. PMID:29268078. longitudinal uncoupling of cerebral perfusion, glucose metabolism, and tau deposition in alzheimer's disease. 2019-07-30 2023-08-13 Not clear
Arne Ittner, Lars M Ittne. Dendritic Tau in Alzheimer's Disease. Neuron. vol 99. issue 1. 2019-07-30. PMID:30001506. dendritic tau in alzheimer's disease. 2019-07-30 2023-08-13 Not clear
Arne Ittner, Lars M Ittne. Dendritic Tau in Alzheimer's Disease. Neuron. vol 99. issue 1. 2019-07-30. PMID:30001506. the microtubule-associated protein tau and amyloid-β (aβ) are key players in alzheimer's disease (ad). 2019-07-30 2023-08-13 Not clear
Li Chen, Jianwei Lin, Jinquan Yi, Qinghua Weng, Ying Zhou, Zhizhong Han, Chunyan Li, Jinghua Chen, Qian Zhan. A tyrosinase-induced fluorescence immunoassay for detection of tau protein using dopamine-functionalized CuInS Analytical and bioanalytical chemistry. vol 411. issue 20. 2019-07-30. PMID:31161325. a tyrosinase-induced fluorescence immunoassay for detection of tau protein using dopamine-functionalized cuins rapid, highly sensitive detection of tau protein and other neurodegenerative biomarkers remains a significant hurdle for diagnostic tests for alzheimer's disease. 2019-07-30 2023-08-13 Not clear
Tommaso Schirinzi, Giulia Di Lazzaro, Vito Luigi Colona, Paola Imbriani, Mohammad Alwardat, Giulia Maria Sancesario, Alessandro Martorana, Antonio Pisan. Assessment of serum uric acid as risk factor for tauopathies. Journal of neural transmission (Vienna, Austria : 1996). vol 124. issue 9. 2019-07-29. PMID:28620833. the mean serum ua concentrations of 111 patients with tauopathies (tau), including 41 with progressive supranuclear palsy (psp), 45 with alzheimer's disease (ad) and 25 with frontotemporal dementia (ftd) were compared to that of 130 controls (ctl). 2019-07-29 2023-08-13 human
Justin Miron, Cynthia Picard, Nathalie Nilsson, Josée Frappier, Doris Dea, Louise Théroux, Judes Poirie. CDK5RAP2 gene and tau pathophysiology in late-onset sporadic Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 6. 2019-07-29. PMID:29360470. cdk5rap2 gene and tau pathophysiology in late-onset sporadic alzheimer's disease. 2019-07-29 2023-08-13 Not clear
Stephen T Chen, Prabha Siddarth, David A Merrill, Jacqueline Martinez, Natacha D Emerson, Jie Liu, Koon-Pong Wong, Nagichettiar Satyamurthy, Christopher C Giza, Sung-Cheng Huang, Robert P Fitzsimmons, Julian Bailes, Bennet Omalu, Jorge R Barrio, Gary W Smal. FDDNP-PET Tau Brain Protein Binding Patterns in Military Personnel with Suspected Chronic Traumatic Encephalopathy1. Journal of Alzheimer's disease : JAD. vol 65. issue 1. 2019-07-29. PMID:30040711. our group has shown that in vivo tau brain binding patterns from fddnp-pet scans in retired professional football players with suspected chronic traumatic encephalopathy differ from those of tau and amyloid aggregate binding observed in alzheimer's disease (ad) patients and cognitively-intact controls. 2019-07-29 2023-08-13 Not clear