All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Hye-Jin Park, Kang-Woo Lee, Stephanie Oh, Run Yan, Jie Zhang, Thomas G Beach, Charles H Adler, Michael Voronkov, Steven P Braithwaite, Jeffry B Stock, M Maral Mouradia. Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease. Journal of neuropathology and experimental neurology. vol 77. issue 2. 2019-06-28. PMID:29281045. hyperphosphorylated tau aggregates are characteristic of tauopathies including progressive supranuclear palsy (psp) and alzheimer disease (ad), but factors contributing to pathologic tau phosphorylation are not well understood. 2019-06-28 2023-08-13 Not clear
Nicolai Franzmeier, Emrah Düzel, Frank Jessen, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Christian Haass, Marc Suárez-Calvet, Anne M Fagan, Katrina Paumier, Tammie Benzinger, Colin L Masters, John C Morris, Robert Perneczky, Daniel Janowitz, Cihan Catak, Steffen Wolfsgruber, Michael Wagner, Stefan Teipel, Ingo Kilimann, Alfredo Ramirez, Martin Rossor, Mathias Jucker, Jasmeer Chhatwal, Annika Spottke, Henning Boecker, Frederic Brosseron, Peter Falkai, Klaus Fliessbach, Michael T Heneka, Christoph Laske, Peter Nestor, Oliver Peters, Manuel Fuentes, Felix Menne, Josef Priller, Eike J Spruth, Christiana Franke, Anja Schneider, Barbara Kofler, Christine Westerteicher, Oliver Speck, Jens Wiltfang, Claudia Bartels, Miguel Ángel Araque Caballero, Coraline Metzger, Daniel Bittner, Michael Weiner, Jae-Hong Lee, Stephen Salloway, Adrian Danek, Alison Goate, Peter R Schofield, Randall J Bateman, Michael Ewer. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a journal of neurology. vol 141. issue 4. 2019-06-28. PMID:29462334. as a marker of disease stage, we applied estimated years from symptom onset in autosomal dominantly inherited alzheimer's disease and cerebrospinal fluid tau levels in sporadic alzheimer's disease cases. 2019-06-28 2023-08-13 human
Remika Mito, David Raffelt, Thijs Dhollander, David N Vaughan, J-Donald Tournier, Olivier Salvado, Amy Brodtmann, Christopher C Rowe, Victor L Villemagne, Alan Connell. Reply: Cortical tau pathology: a major player in fibre-specific white matter reductions in Alzheimer's disease? Brain : a journal of neurology. vol 141. issue 6. 2019-06-28. PMID:29668851. reply: cortical tau pathology: a major player in fibre-specific white matter reductions in alzheimer's disease? 2019-06-28 2023-08-13 Not clear
Kirsty E McAleese, Lauren Walker, Sean J Colloby, John-Paul Taylor, Alan J Thomas, Charles DeCarli, Johannes Attem. Cortical tau pathology: a major player in fibre-specific white matter reductions in Alzheimer's disease? Brain : a journal of neurology. vol 141. issue 6. 2019-06-28. PMID:29668888. cortical tau pathology: a major player in fibre-specific white matter reductions in alzheimer's disease? 2019-06-28 2023-08-13 Not clear
Oskar Hansson, Elizabeth C Mormin. Is longitudinal tau PET ready for use in Alzheimer's disease clinical trials? Brain : a journal of neurology. vol 141. issue 5. 2019-06-27. PMID:29701788. is longitudinal tau pet ready for use in alzheimer's disease clinical trials? 2019-06-27 2023-08-13 Not clear
Justin L Hoskin, Marwan Noel Sabbagh, Yazan Al-Hasan, Boris Decour. Tau immunotherapies for Alzheimer's disease. Expert opinion on investigational drugs. vol 28. issue 6. 2019-06-27. PMID:31094578. tau immunotherapies for alzheimer's disease. 2019-06-27 2023-08-13 Not clear
Mehmet I Cosacak, Prabesh Bhattarai, Ledio Bocova, Tim Dzewas, Violeta Mashkaryan, Christos Papadimitriou, Kerstin Brandt, Heike Hollak, Christopher L Antos, Caghan Kizi. Human TAU Scientific reports. vol 7. issue 1. 2019-06-26. PMID:29021554. human tau microtubule-associated tau protein is a pathological hallmark in alzheimer's disease (ad), where hyperphosphorylation of tau generates neurofibrillary tangles. 2019-06-26 2023-08-13 human
Ville Leinonen, Tuomas Rauramaa, Jarkko Johansson, Astrid Bottelbergs, Ina Tesseur, Peter van der Ark, Darrel Pemberton, Anne M Koivisto, Juha E Jääskeläinen, Mikko Hiltunen, Sanna-Kaisa Herukka, Kaj Blennow, Henrik Zetterberg, Pekka Jokinen, Johanna Rokka, Semi Helin, Merja Haaparanta-Solin, Olof Solin, Nobuyuki Okamura, Hartmuth C Kolb, Juha O Rinn. S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies. Journal of Alzheimer's disease : JAD. vol 64. issue 1. 2019-06-26. PMID:29865068. detection of pathological tau aggregates could facilitate clinical diagnosis of alzheimer's disease (ad) and monitor drug effects in clinical trials. 2019-06-26 2023-08-13 Not clear
Guang Fang, Baoyan Shi, Kefeng Wu, Siyu Chen, Xiang Gao, Sa Xiao, Jing X Kang, Wende Li, Ren Huan. The protective role of endogenous n-3 polyunsaturated fatty acids in Tau Alzheimer's disease mouse model. The International journal of neuroscience. vol 129. issue 4. 2019-06-26. PMID:30296191. the protective role of endogenous n-3 polyunsaturated fatty acids in tau alzheimer's disease mouse model. 2019-06-26 2023-08-13 mouse
Marc J Kaufman, Gen Kanayama, James I Hudson, Harrison G Pop. Supraphysiologic-dose anabolic-androgenic steroid use: A risk factor for dementia? Neuroscience and biobehavioral reviews. vol 100. 2019-06-26. PMID:30817935. supraphysiologic-dose anabolic-androgenic steroid (aas) use is associated with physiologic, cognitive, and brain abnormalities similar to those found in people at risk for developing alzheimer's disease and its related dementias (ad/adrd), which are associated with high brain β-amyloid (aβ) and hyperphosphorylated tau (tau-p) protein levels. 2019-06-26 2023-08-13 Not clear
David Wolk, Stephen Salloway, Brad Dickerso. Putting the New Alzheimer Disease Amyloid, Tau, Neurodegeneration (AT[N]) Diagnostic System to the Test. JAMA. vol 321. issue 23. 2019-06-26. PMID:31211328. putting the new alzheimer disease amyloid, tau, neurodegeneration (at[n]) diagnostic system to the test. 2019-06-26 2023-08-13 Not clear
Tian Liu, Fang Wang, Patrick LePochat, Jung-A A Woo, Mohammed Zaheen Bukhari, Kyung Woo Hong, Courtney Trotter, David E Kan. Cofilin-mediated Neuronal Apoptosis via p53 Translocation and PLD1 Regulation. Scientific reports. vol 7. issue 1. 2019-06-24. PMID:28912445. amyloid β (aβ) accumulation is an early event in the pathogenesis of alzheimer's disease (ad), leading to mitochondrial and synaptic dysfunction, tau accumulation, and eventual neuronal death. 2019-06-24 2023-08-13 mouse
Chin Hong Tan, Chun Chieh Fan, Elizabeth C Mormino, Leo P Sugrue, Iris J Broce, Christopher P Hess, William P Dillon, Luke W Bonham, Jennifer S Yokoyama, Celeste M Karch, James B Brewer, Gil D Rabinovici, Bruce L Miller, Gerard D Schellenberg, Karolina Kauppi, Howard A Feldman, Dominic Holland, Linda K McEvoy, Bradley T Hyman, David A Bennett, Ole A Andreassen, Anders M Dale, Rahul S Desika. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta neuropathologica. vol 135. issue 1. 2019-06-24. PMID:29177679. polygenic hazard score: an enrichment marker for alzheimer's associated amyloid and tau deposition. 2019-06-24 2023-08-13 Not clear
Chin Hong Tan, Chun Chieh Fan, Elizabeth C Mormino, Leo P Sugrue, Iris J Broce, Christopher P Hess, William P Dillon, Luke W Bonham, Jennifer S Yokoyama, Celeste M Karch, James B Brewer, Gil D Rabinovici, Bruce L Miller, Gerard D Schellenberg, Karolina Kauppi, Howard A Feldman, Dominic Holland, Linda K McEvoy, Bradley T Hyman, David A Bennett, Ole A Andreassen, Anders M Dale, Rahul S Desika. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta neuropathologica. vol 135. issue 1. 2019-06-24. PMID:29177679. here, we evaluated whether a recently validated polygenic hazard score (phs) can be integrated with known in vivo cerebrospinal fluid (csf) or positron emission tomography (pet) biomarkers of amyloid, and csf tau pathology to prospectively predict cognitive and clinical decline in 347 cognitive normal (cn; baseline age range = 59.7-90.1, 98.85% white) and 599 mild cognitively impaired (mci; baseline age range = 54.4-91.4, 98.83% white) individuals from the alzheimer's disease neuroimaging initiative 1, go, and 2. 2019-06-24 2023-08-13 Not clear
Michel Goeder. Tau filaments in neurodegenerative diseases. FEBS letters. vol 592. issue 14. 2019-06-24. PMID:29790176. thirty years ago, we reported that tau is an integral component of the intraneuronal filaments of alzheimer's disease. 2019-06-24 2023-08-13 human
Bianca Hutter-Schmid, Christian Humpe. Primary mouse brain pericytes isolated from transgenic Alzheimer mice spontaneously differentiate into a CD11b Experimental gerontology. vol 112. 2019-06-24. PMID:30099090. primary mouse brain pericytes isolated from transgenic alzheimer mice spontaneously differentiate into a cd11b alzheimer's disease (ad) is characterized by amyloid-β plaques, tau pathology and vascular impairment including pericyte damage. 2019-06-24 2023-08-13 mouse
Takanobu Suzuki, Yukiko Hori, Taka Sawazaki, Yusuke Shimizu, Yu Nemoto, Atsuhiko Taniguchi, Shuta Ozawa, Youhei Sohma, Motomu Kanai, Taisuke Tomit. Photo-oxygenation inhibits tau amyloid formation. Chemical communications (Cambridge, England). vol 55. issue 44. 2019-06-24. PMID:31049495. tau amyloid formation and deposition are responsible for the onset of alzheimer's disease. 2019-06-24 2023-08-13 human
Kevin H Strang, Zachary A Sorrentino, Cara J Riffe, Kimberly-Marie M Gorion, Niran Vijayaraghavan, Todd E Golde, Benoit I Giasso. Phosphorylation of serine 305 in tau inhibits aggregation. Neuroscience letters. vol 692. 2019-06-21. PMID:30423399. alzheimer's disease and other tauopathies are characterized by the brain accumulation of hyperphosphorylated aggregated tau protein forming pathological inclusions. 2019-06-21 2023-08-13 Not clear
Kevin H Strang, Zachary A Sorrentino, Cara J Riffe, Kimberly-Marie M Gorion, Niran Vijayaraghavan, Todd E Golde, Benoit I Giasso. Phosphorylation of serine 305 in tau inhibits aggregation. Neuroscience letters. vol 692. 2019-06-21. PMID:30423399. consistent with inhibition of tau aggregation, phosphorylation of s305 was not detected in pathological tau inclusions in alzheimer's disease brain tissue. 2019-06-21 2023-08-13 Not clear
Sarah Gourmaud, Priscilla Thomas, Sylvie Thomasseau, Marion Tible, Claire Abadie, Claire Paquet, Jacques Hugo. Brimapitide Reduced Neuronal Stress Markers and Cognitive Deficits in 5XFAD Transgenic Mice. Journal of Alzheimer's disease : JAD. vol 63. issue 2. 2019-06-18. PMID:29660941. alzheimer's disease (ad) is characterized by accumulations of amyloid-β (aβ42) and hyperphosphorylated tau proteins, associated with neuroinflammation, synaptic loss, and neuronal death. 2019-06-18 2023-08-13 mouse