| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valentina Sturiale, Francesca Bruno, Desiree Brancato, Agata Grazia D'Amico, Grazia Maugeri, Velia D'Agata, Salvatore Saccone, Concetta Federic. Cell Cycle Reactivation, at the Start of Neurodegeneration, Induced by Forskolin and Aniline in Differentiated Neuroblastoma Cells. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762676. |
a characteristic hallmark of alzheimer's disease (ad) is the intracellular accumulation of hyperphosphorylated tau protein, a phenomenon that appears to have associations with oxidative stress, double-stranded dna breakage, and the de-condensation of heterochromatin. |
2023-09-28 |
2023-10-07 |
Not clear |
| Meixiang Huang, Carolyn Tallon, Xiaolei Zhu, Kaitlyn D J Huizar, Silvia Picciolini, Ajit G Thomas, Lukas Tenora, Wathsala Liyanage, Francesca Rodà, Alice Gualerzi, Rangaramanujam M Kannan, Marzia Bedoni, Rana Rais, Barbara S Slushe. Microglial-Targeted nSMase2 Inhibitor Fails to Reduce Tau Propagation in PS19 Mice. Pharmaceutics. vol 15. issue 9. 2023-09-28. PMID:37765332. |
the progression of alzheimer's disease (ad) correlates with the propagation of hyperphosphorylated tau (ptau) from the entorhinal cortex to the hippocampus and neocortex. |
2023-09-28 |
2023-10-07 |
mouse |
| Yurie Fukiyama, Takahisa Hirokawa, Shinji Takai, Teruyo Kida, Hidehiro Ok. Involvement of Glycogen Synthase Kinase 3β (GSK3β) in Formation of Phosphorylated Tau and Death of Retinal Ganglion Cells of Rats Caused by Optic Nerve Crush. Current issues in molecular biology. vol 45. issue 9. 2023-09-27. PMID:37754222. |
it has been proposed that glycogen synthase kinase 3β (gsk3β) is involved in the hyperphosphorylation of tau in alzheimer's disease. |
2023-09-27 |
2023-10-07 |
rat |
| Forough Chakari-Khiavi, Arezoo Mirzaie, Balal Khalilzadeh, Hadi Yousefi, Rozita Abolhasan, Amin Kamrani, Ramin Pourakbari, Koorosh Shahpasand, Mehdi Yousefi, Mohammad-Reza Rashid. Application of Pt@ZIF-8 nanocomposite-based electrochemical biosensor for sensitive diagnosis of tau protein in Alzheimer's disease patients. Scientific reports. vol 13. issue 1. 2023-09-27. PMID:37758805. |
application of pt@zif-8 nanocomposite-based electrochemical biosensor for sensitive diagnosis of tau protein in alzheimer's disease patients. |
2023-09-27 |
2023-10-07 |
Not clear |
| Chun Xu, Danqing Xiao, Brenda Bin Su, Jaime Miguel Saveron, Daniela Gamez, R Osvaldo Navia, Nianyang Wang, Upal Roy, Donald A Adjeroh, Kesheng Wan. Association of APOE gene with longitudinal changes of CSF amyloid beta and tau levels in Alzheimer's disease: racial differences. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. 2023-09-27. PMID:37759100. |
association of apoe gene with longitudinal changes of csf amyloid beta and tau levels in alzheimer's disease: racial differences. |
2023-09-27 |
2023-10-07 |
Not clear |
| Genevieve L Stein-O'Brien, Ryan Palaganas, Ernest M Meyer, Javier Redding-Ochoa, Olga Pletnikova, Haidan Guo, William R Bell, Juan C Troncoso, Richard L Huganir, Meaghan Morri. Transcriptional Signatures of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer's Disease. medRxiv : the preprint server for health sciences. 2023-09-25. PMID:37745408. |
transcriptional signatures of hippocampal tau pathology in primary age-related tauopathy and alzheimer's disease. |
2023-09-25 |
2023-10-07 |
Not clear |
| Genevieve L Stein-O'Brien, Ryan Palaganas, Ernest M Meyer, Javier Redding-Ochoa, Olga Pletnikova, Haidan Guo, William R Bell, Juan C Troncoso, Richard L Huganir, Meaghan Morri. Transcriptional Signatures of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer's Disease. medRxiv : the preprint server for health sciences. 2023-09-25. PMID:37745408. |
tau pathology in primary age-related tauopathy (part) and in alzheimer's disease (ad) has a similar biochemical structure and anatomic distribution, which is distinct from tau pathology in other diseases. |
2023-09-25 |
2023-10-07 |
Not clear |
| Feng Han, JiaQie Lee, Xi Chen, Jacob Ziontz, Tyler Ward, Susan M Landau, Suzanne L Baker, Theresa M Harrison, William J Jagus. Global brain activity and its coupling with cerebrospinal fluid flow is related to tau pathology. bioRxiv : the preprint server for biology. 2023-09-25. PMID:37745434. |
amyloid-β (aβ) and tau deposition constitute alzheimer's disease (ad) neuropathology. |
2023-09-25 |
2023-10-07 |
human |
| Benjamin C Creekmore, Kathryn Kixmoeller, Ben E Black, Edward B Lee, Yi-Wei Chan. Native ultrastructure of fresh human brain vitrified directly from autopsy revealed by cryo-electron tomography with cryo-plasma focused ion beam milling. bioRxiv : the preprint server for biology. 2023-09-25. PMID:37745569. |
lamellae generated in alzheimer's disease brain tissue and imaged by cryo-et reveal intact subcellular structures including components of autophagy and potential tau fibrils. |
2023-09-25 |
2023-10-07 |
human |
| Eva Lepinay, Francesca Cicchett. Tau: a biomarker of Huntington's disease. Molecular psychiatry. 2023-09-25. PMID:37749233. |
we have herein reviewed the literature pertaining to the association between tau levels and cognitive states, zooming in on alzheimer's disease, parkinson's disease and traumatic brain injury in which imaging, cerebrospinal fluid, and blood samples have been interrogated or used to unveil a strong association between tau and cognition. |
2023-09-25 |
2023-10-07 |
Not clear |
| Tiffany E Chow, Christina R Veziris, Nidhi Mundada, Alexis I Martinez-Arroyo, Joel H Kramer, Bruce L Miller, Howard J Rosen, Maria Luisa Gorno-Tempini, Katherine P Rankin, William W Seeley, Gil D Rabinovici, Renaud La Joie, Virginia E Stur. Medial Temporal Lobe Tau Aggregation Relates to Divergent Cognitive and Emotional Empathy Abilities in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-09-24. PMID:37742643. |
medial temporal lobe tau aggregation relates to divergent cognitive and emotional empathy abilities in alzheimer's disease. |
2023-09-24 |
2023-10-07 |
Not clear |
| Tiffany E Chow, Christina R Veziris, Nidhi Mundada, Alexis I Martinez-Arroyo, Joel H Kramer, Bruce L Miller, Howard J Rosen, Maria Luisa Gorno-Tempini, Katherine P Rankin, William W Seeley, Gil D Rabinovici, Renaud La Joie, Virginia E Stur. Medial Temporal Lobe Tau Aggregation Relates to Divergent Cognitive and Emotional Empathy Abilities in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-09-24. PMID:37742643. |
in alzheimer's disease (ad), the gradual accumulation of amyloid-β (aβ) and tau proteins may underlie alterations in empathy. |
2023-09-24 |
2023-10-07 |
Not clear |
| Lavanya Jain, Maria Khrestian, Shane Formica, Elizabeth D Tuason, Jagan A Pillai, Stephen Rao, Odinachi Oguh, Carol F Lippa, Oscar L Lopez, Sarah B Berman, Debby W Tsuang, Cyrus P Zabetian, David J Irwin, Douglas R Galasko, Irene Litvan, Karen S Marder, Lawrence S Honig, Jori E Fleisher, James E Galvin, Andrea C Bozoki, Angela S Taylor, Marwan N Sabbagh, James B Leverenz, Lynn M Bekri. ATN cerebrospinal fluid biomarkers in dementia with Lewy bodies: Initial results from the United States Dementia with Lewy Bodies Consortium. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-09-23. PMID:37740924. |
the national institute on aging - alzheimer's association (nia-aa) atn research framework proposes to use biomarkers for amyloid (a), tau (t), and neurodegeneration (n) to stage individuals with ad pathological features and track changes longitudinally. |
2023-09-23 |
2023-10-07 |
Not clear |
| Salvatore P Mangiafico, Qing-Zhang Tuo, Xiao-Lan Li, Yu Liu, Christian Haralambous, Xu-Long Ding, Scott Ayton, Qing Wang, D Ross Laybutt, Jeng Yie Chan, Xiang Zhang, Cameron Kos, Helen E Thomas, Thomas Loudovaris, Chieh-Hsin Yang, Christos N Joannides, Benjamin J Lamont, Lunzhi Dai, Hai-Huai He, Biao Dong, Sofianos Andrikopoulos, Ashley I Bush, Peng Le. Tau suppresses microtubule-regulated pancreatic insulin secretion. Molecular psychiatry. 2023-09-22. PMID:37735502. |
tau protein is implicated in the pathogenesis of alzheimer's disease (ad) and other tauopathies, but its physiological function is in debate. |
2023-09-22 |
2023-10-07 |
mouse |
| Wyatt C Powell, Ruiheng Jing, Maciej A Walcza. Chemical Synthesis of Microtubule-Associated Protein Tau. Journal of the American Chemical Society. 2023-09-22. PMID:37737824. |
numerous studies have demonstrated that in diseases such as alzheimer's disease (ad), tau undergoes extensive remodeling. |
2023-09-22 |
2023-10-07 |
Not clear |
| Pijush Chakraborty, Gwladys Rivière, Alina Hebestreit, Alain Ibáñez de Opakua, Ina M Vorberg, Loren B Andreas, Markus Zweckstette. Acetylation discriminates disease-specific tau deposition. Nature communications. vol 14. issue 1. 2023-09-22. PMID:37739953. |
pathogenic aggregation of the protein tau is a hallmark of alzheimer's disease and several other tauopathies. |
2023-09-22 |
2023-10-07 |
Not clear |
| Nidhi S Mundada, Julio C Rojas, Lawren Vandevrede, Elisabeth H Thijssen, Leonardo Iaccarino, Obiora C Okoye, Ranjani Shankar, David N Soleimani-Meigooni, Argentina L Lago, Bruce L Miller, Charlotte E Teunissen, Hillary Heuer, Howie J Rosen, Jeffrey L Dage, William J Jagust, Gil D Rabinovici, Adam L Boxer, Renaud La Joi. Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment. Alzheimer's research & therapy. vol 15. issue 1. 2023-09-22. PMID:37740209. |
plasma phosphorylated tau (p-tau) has emerged as a promising biomarker for alzheimer's disease (ad). |
2023-09-22 |
2023-10-07 |
Not clear |
| Michelle M Coleman, Cierra M Keith, Kirk Wilhelmsen, Rashi I Mehta, Camila Vieira Ligo Teixeira, Mark Miller, Melanie Ward, Ramiro Osvaldo Navia, William T McCuddy, Pierre-François D'Haese, Marc W Hau. Surface-based correlates of cognition along the Alzheimer's continuum in a memory clinic population. Frontiers in neurology. vol 14. 2023-09-21. PMID:37731852. |
composite cognitive measures in large-scale studies with biomarker data for amyloid and tau have been widely used to characterize alzheimer's disease (ad). |
2023-09-21 |
2023-10-07 |
Not clear |
| Cristina Di Primio, Paola Quaranta, Marianna Mignanelli, Giacomo Siano, Matteo Bimbati, Arianna Scarlatti, Carmen Rita Piazza, Piero Giorgio Spezia, Paola Perrera, Fulvio Basolo, Anello Marcello Poma, Mario Costa, Mauro Pistello, Antonino Cattane. Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neurons. PNAS nexus. vol 2. issue 9. 2023-09-21. PMID:37731949. |
upon infection, tau is phosphorylated at several pathological epitopes associated with alzheimer's disease and other tauopathies. |
2023-09-21 |
2023-10-07 |
mouse |
| Nina Rostgaard, Pia Holm Jul, Mats Garmer, Christiane Volbrach. Increasing O-GlcNAcylation Attenuates tau Hyperphosphorylation and Behavioral Impairment in rTg4510 Tauopathy Mice. Journal of integrative neuroscience. vol 22. issue 5. 2023-09-21. PMID:37735138. |
tauopathies such as alzheimer's disease (ad) are characterized by abnormal hyperphosphorylation of the microtubule-associated protein tau (mapt) aggregating into neurofibrillary tangles (nfts). |
2023-09-21 |
2023-10-07 |
mouse |