| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yu Zou, Bote Qi, Jingwang Tan, Lulu Guan, Qingwen Zhang, Yunxiang Sun, Fengjuan Huan. Deciphering the Inhibitory Mechanism of Naphthoquinone-Dopamine on the Aggregation of Tau Core Fragments PHF6* and PHF6. ACS chemical neuroscience. 2023-08-16. PMID:37585669. |
the formation of neurofibrillary tangles by abnormal aggregation of tau protein is considered to be an important pathological characteristic of tauopathies, including alzheimer's disease and chronic traumatic encephalopathy. |
2023-08-16 |
2023-09-07 |
Not clear |
| Xin Wang, Erin E Sundermann, Rachel F Buckley, Emilie T Reas, Linda K McEvoy, Sarah J Bank. Sex Differences in the Associations of Obesity with Tau, Amyloid PET, and Cognitive Outcomes in Preclinical Alzheimer's Disease: Cross-Sectional A4 Study. Journal of Alzheimer's disease : JAD. 2023-08-14. PMID:37574737. |
sex differences in the associations of obesity with tau, amyloid pet, and cognitive outcomes in preclinical alzheimer's disease: cross-sectional a4 study. |
2023-08-14 |
2023-08-16 |
Not clear |
| Yao Zhu, Yan Wu, Xinyi Lv, Jiaonan Wu, Chunzi Shen, Qiqiang Tang, Guoping Wan. The relationship between APOE genotype, CSF Tau and cognition across the Alzheimer's disease spectrum, moderation and mediation role of insula network connectivity. CNS neuroscience & therapeutics. 2023-08-14. PMID:37577852. |
the relationship between apoe genotype, csf tau and cognition across the alzheimer's disease spectrum, moderation and mediation role of insula network connectivity. |
2023-08-14 |
2023-08-16 |
Not clear |
| Yao Zhu, Yan Wu, Xinyi Lv, Jiaonan Wu, Chunzi Shen, Qiqiang Tang, Guoping Wan. The relationship between APOE genotype, CSF Tau and cognition across the Alzheimer's disease spectrum, moderation and mediation role of insula network connectivity. CNS neuroscience & therapeutics. 2023-08-14. PMID:37577852. |
to investigate whether insula network connectivity modulates the relationship between apolipoprotein e (apoe) ε4 genotype, cerebrospinal fluid (csf) biomarkers (aβ, tau, and ptau) and cognition across alzheimer's disease (ad) spectrum. |
2023-08-14 |
2023-08-16 |
Not clear |
| Shuo Liu, Luting Xu, Yan Shen, Liuying Wang, Xiaoxiao Lai, Haiyan H. Qingxin Kaiqiao Fang decreases Tau hyperphosphorylation in Alzheimer's disease via the PI3K/Akt/GSK3β pathway in vitro and in vivo. Journal of ethnopharmacology. 2023-08-14. PMID:37579924. |
qingxin kaiqiao fang decreases tau hyperphosphorylation in alzheimer's disease via the pi3k/akt/gsk3β pathway in vitro and in vivo. |
2023-08-14 |
2023-09-07 |
Not clear |
| Bartolo Tamburini, Giusto Davide Badami, Marco Pio La Manna, Mojtaba Shekarkar Azgomi, Nadia Caccamo, Francesco Diel. Emerging Roles of Cells and Molecules of Innate Immunity in Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569296. |
in this review, we focus on the role of cells (microglia, astrocytes, and oligodendrocytes) and molecules (trem2, tau, and β-amyloid) of the innate immune system in the pathogenesis of alzheimer's disease and their possible exploitation as disease biomarkers and targets of therapeutical approaches. |
2023-08-12 |
2023-08-16 |
Not clear |
| Sofia Toniolo, Francesco Di Lorenzo, Sergio Bernardini, Nicola Biagio Mercuri, Giulia Maria Sancesari. Blood-Brain Barrier Dysfunction and Aβ42/40 Ratio Dose-Dependent Modulation with the ApoE Genotype within the ATN Framework. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569528. |
the definition of alzheimer's disease (ad) now considers the presence of the markers of amyloid (a), tau deposition (t), and neurodegeneration (n) essential for diagnosis. |
2023-08-12 |
2023-08-16 |
Not clear |
| Ruth Maron, Yaron Vinik, Michael Tsoory, Meir Wilchek, Ruth Arno. Amyloid Precursor Protein and Tau Peptides Linked Together Ameliorate Loss of Cognition in an Alzheimer's Disease Animal Model. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569901. |
amyloid precursor protein and tau peptides linked together ameliorate loss of cognition in an alzheimer's disease animal model. |
2023-08-12 |
2023-08-16 |
mouse |
| Ruth Maron, Yaron Vinik, Michael Tsoory, Meir Wilchek, Ruth Arno. Amyloid Precursor Protein and Tau Peptides Linked Together Ameliorate Loss of Cognition in an Alzheimer's Disease Animal Model. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569901. |
the major proteins involved in alzheimer's disease (ad) are amyloid precursor protein (app) and tau. |
2023-08-12 |
2023-08-16 |
mouse |
| Roz R Limpengco, Christopher Liang, Yasmin K Sandhu, Jogeshwar Mukherje. [ Molecules (Basel, Switzerland). vol 28. issue 15. 2023-08-12. PMID:37570739. |
[ aggregation of tau protein into paired helical filaments causing neurofibrillary tangles (nft) is a neuropathological feature in alzheimer's disease (ad). |
2023-08-12 |
2023-08-16 |
Not clear |
| Annika van Hummel, Goce Taleski, Jean-Marie Sontag, Astrid Feentje Feiten, Yazi D Ke, Lars M Ittner, Estelle Sonta. Methyl donor supplementation reduces phospho-Tau, Fyn and demethylated PP2A levels, and mitigates learning and motor deficits in a mouse model of tauopathy. Neuropathology and applied neurobiology. 2023-08-11. PMID:37565253. |
disturbances in one-carbon metabolism are associated with the pathological accumulation of phosphorylated tau, a hallmark feature of prevalent dementia, including alzheimer's disease and subgroups of frontotemporal dementia. |
2023-08-11 |
2023-08-16 |
mouse |
| Rimil Guha Roy, Pravat K Mandal, Joseph C Maroo. Oxidative Stress Occurs Prior to Amyloid Aβ Plaque Formation and Tau Phosphorylation in Alzheimer's Disease: Role of Glutathione and Metal Ions. ACS chemical neuroscience. 2023-08-10. PMID:37561556. |
oxidative stress occurs prior to amyloid aβ plaque formation and tau phosphorylation in alzheimer's disease: role of glutathione and metal ions. |
2023-08-10 |
2023-08-16 |
Not clear |
| Swati Rane Levendovszk. Cross-Sectional and Longitudinal Hippocampal Atrophy, Not Cortical Thinning, Occurs in Amyloid-Negative, p-Tau-Positive, Older Adults With Non-Amyloid Pathology and Mild Cognitive Impairment. Frontiers in neuroimaging. vol 1. 2023-08-09. PMID:37555137. |
alzheimer's disease (ad) is a degenerative disease characterized by pathological accumulation of amyloid and phosphorylated tau. |
2023-08-09 |
2023-08-16 |
human |
| Min Young Chun, Hyemin Jang, Soo-Jong Kim, Yu Hyun Park, Jihwan Yun, Samuel N Lockhart, Michael Weiner, Charles De Carli, Seung Hwan Moon, Jae Yong Choi, Kyung Rok Nam, Byung-Hyun Byun, Sang-Moo Lim, Jun Pyo Kim, Yeong Sim Choe, Young Ju Kim, Duk L Na, Hee Jin Kim, Sang Won Se. Emerging role of vascular burden in AT(N) classification in individuals with Alzheimer's and concomitant cerebrovascular burdens. Journal of neurology, neurosurgery, and psychiatry. 2023-08-09. PMID:37558399. |
alzheimer's disease (ad) is characterised by amyloid-beta accumulation (a), tau aggregation (t) and neurodegeneration (n). |
2023-08-09 |
2023-08-16 |
Not clear |
| Qianyun Chen, Jill Abrigo, Min Deng, Lin Shi, Yi-Xiang Wang, Winnie Cw Ch. Structural network topology reveals higher brain resilience in individuals with preclinical Alzheimer's disease. Brain connectivity. 2023-08-08. PMID:37551987. |
the diagnosis of alzheimer's disease (ad) requires the presence of amyloid and tau pathology, but it remains unclear how they affect structural network in the preclinical stage. |
2023-08-08 |
2023-08-14 |
Not clear |
| Debashis Dutta, Malabendu Jana, Ramesh Kumar Paidi, Moumita Majumder, Sumita Raha, Sridevi Dasarathy, Kalipada Paha. Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models. The Journal of clinical investigation. 2023-08-08. PMID:37552543. |
tau fibrils induce glial inflammation and neuropathology via tlr2 in alzheimer's disease-related mouse models. |
2023-08-08 |
2023-08-16 |
mouse |
| Aurelien Lathuiliere, Youhwa Jo, Romain Perbet, Cameron Donahue, Caitlin Commins, Noé Quittot, Zhanyun Fan, Rachel E Bennett, Bradley T Hyma. Specific detection of tau seeding activity in Alzheimer's disease using rationally designed biosensor cells. Molecular neurodegeneration. vol 18. issue 1. 2023-08-08. PMID:37553663. |
specific detection of tau seeding activity in alzheimer's disease using rationally designed biosensor cells. |
2023-08-08 |
2023-08-16 |
Not clear |
| Mengdi Wu, Ying Li, Yaodong Miao, Huanhuan Qiao, Yiwen Wan. Exploring the efficient natural products for Alzheimer's disease therapy via Journal of drug targeting. 2023-08-07. PMID:37545435. |
exploring the efficient natural products for alzheimer's disease therapy via alzheimer's disease (ad) is a grievous neurodegenerative disorder and a major form of senile dementia, which is partially caused by abnormal amyloid-beta peptide deposition and tau protein phosphorylation. |
2023-08-07 |
2023-08-14 |
Not clear |
| Nur Jury-Garfe, Yanwen You, Pablo Martínez, Javier Redding-Ochoa, Hande Karahan, Travis S Johnson, Jie Zhang, Jungsu Kim, Juan C Troncoso, Cristian A Lasagna-Reeve. Enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in Alzheimer's disease. bioRxiv : the preprint server for biology. 2023-08-07. PMID:37546928. |
enhanced microglial dynamics and paucity of tau seeding in the amyloid plaque microenvironment contributes to cognitive resilience in alzheimer's disease. |
2023-08-07 |
2023-08-14 |
human |
| Jiayi Zhong, Xiaochen Zhang, Huanyu Xu, Xiaoran Zheng, Luyao Wang, Jiehui Jiang, Yunxia L. Unlocking the enigma: unraveling multiple cognitive dysfunction linked to glymphatic impairment in early Alzheimer's disease. Frontiers in neuroscience. vol 17. 2023-08-07. PMID:37547134. |
alzheimer's disease (ad) is one of the world's well-known neurodegenerative diseases, which is related to the balance mechanism of production and clearance of two proteins (amyloid-β and tau) regulated by the glymphatic system. |
2023-08-07 |
2023-08-14 |
Not clear |