| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Avneet Kour, Virendra Tiwari, Nidhi Aggarwal, Himanshu Sekhar Panda, Ashwani Kumar, Siddharth Tiwari, Virander Singh Chauhan, Shubha Shukla, Jiban Jyoti Pand. Anti-amyloidogenic amphipathic arginine-dehydrophenylalanine spheres capped selenium nanoparticles as potent therapeutic moieties for Alzheimer's disease. Nanoscale. 2023-07-21. PMID:37477348. |
aggregation of both amyloid beta (aβ) peptide and hyperphosphorylated tau proteins is the major pathological hallmark of alzheimer's disease (ad). |
2023-07-21 |
2023-08-14 |
Not clear |
| Yingying Wang, Xing Ye, Bo Song, Yixin Yan, Wenyin Ma, Jingping Sh. Features of event-related potentials during retrieval of episodic memory in patients with mild cognitive impairment due to Alzheimer's disease. Frontiers in neuroscience. vol 17. 2023-07-20. PMID:37469837. |
to provide a rigorous comparison between patients with mild cognitive impairment due to alzheimer's disease (mci-ad) and healthy elderly, as well as to assess the value of electroencephalography (eeg) in terms of early diagnosis, we conducted a neutral image recognition memory task involving individuals with positive biomarkers including β amyloid deposition, pathologic tau or neurodegeneration. |
2023-07-20 |
2023-08-14 |
Not clear |
| Hiroki Umeda, Taka Sawazaki, Masahiro Furuta, Takanobu Suzuki, Shigehiro A Kawashima, Harunobu Mitsunuma, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kana. Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins. ACS chemical neuroscience. 2023-07-20. PMID:37470225. |
quantitative assays for catalytic photo-oxygenation of alzheimer disease-related tau proteins. |
2023-07-20 |
2023-08-14 |
Not clear |
| Hiroki Umeda, Taka Sawazaki, Masahiro Furuta, Takanobu Suzuki, Shigehiro A Kawashima, Harunobu Mitsunuma, Yukiko Hori, Taisuke Tomita, Youhei Sohma, Motomu Kana. Quantitative Assays for Catalytic Photo-Oxygenation of Alzheimer Disease-Related Tau Proteins. ACS chemical neuroscience. 2023-07-20. PMID:37470225. |
catalytic photo-oxygenation of tau amyloid is a potential therapeutic approach to tauopathies, including alzheimer disease (ad). |
2023-07-20 |
2023-08-14 |
Not clear |
| Víctor Navalón-Monllor, Laura Soriano-Romaní, Mariana Silva, María-Carmen López de Las Hazas, Natalia Hernando-Quintana, Teodoro Suárez Diéguez, Pere Morell Esteve, Juan Antonio Niet. Microbiota dysbiosis caused by dietetic patterns as a promoter of Alzheimer's disease through metabolic syndrome mechanisms. Food & function. 2023-07-20. PMID:37470232. |
at the brain and neuronal levels, the generated insulin resistance, low-grade chronic inflammation, leptin resistance, age production and lps increase directly impact the secretase enzymes and tau hyperphosphorylation, creating an enabling environment for β-amyloid senile plaque and tau tangled formations and, as a consequence, alzheimer's initiation, development and maintenance. |
2023-07-20 |
2023-08-14 |
Not clear |
| Roberto Tira, Giovanna Viola, Carlo Giorgio Barracchia, Francesca Parolini, Francesca Munari, Stefano Capaldi, Michael Assfalg, Mariapina D'Onofri. Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer's Associated Tau Protein. Journal of agricultural and food chemistry. 2023-07-19. PMID:37466260. |
espresso coffee mitigates the aggregation and condensation of alzheimer's associated tau protein. |
2023-07-19 |
2023-08-14 |
Not clear |
| Roberto Tira, Giovanna Viola, Carlo Giorgio Barracchia, Francesca Parolini, Francesca Munari, Stefano Capaldi, Michael Assfalg, Mariapina D'Onofri. Espresso Coffee Mitigates the Aggregation and Condensation of Alzheimer's Associated Tau Protein. Journal of agricultural and food chemistry. 2023-07-19. PMID:37466260. |
alzheimer's disease belongs to a group of disorders, called tauopathies, which are characterized by the intraneuronal accumulation of the microtubule-associated protein tau in fibrillar aggregates. |
2023-07-19 |
2023-08-14 |
Not clear |
| Yejoo Choi, Sungho Shin, Hyo Jin Son, Na-Hee Lee, Su Hyeon Myeong, Cheolju Lee, Hyemin Jang, Soo Jin Choi, Hee Jin Kim, Duk L N. Identification of potential biomarkers related to mesenchymal stem cell response in patients with Alzheimer's disease. Stem cell research & therapy. vol 14. issue 1. 2023-07-19. PMID:37468918. |
preclinical studies showed that mesenchymal stem cells (mscs) ameliorate tau phosphorylation, amyloid-beta accumulation, and inflammation in alzheimer's disease (ad) mouse models via secretion of neurotrophic factors and cytokines. |
2023-07-19 |
2023-08-14 |
mouse |
| Katherine R Sadleir, Robert Vassa. Connections between ApoE, sleep, and Aβ and tau pathologies in Alzheimer's disease. The Journal of clinical investigation. vol 133. issue 14. 2023-07-18. PMID:37463448. |
connections between apoe, sleep, and aβ and tau pathologies in alzheimer's disease. |
2023-07-18 |
2023-08-14 |
mouse |
| Sebastian Palmqvist, Marcello Rossi, Sara Hall, Corinne Quadalti, Niklas Mattsson-Carlgren, Sofia Dellavalle, Pontus Tideman, Joana B Pereira, Maria H Nilsson, Angela Mammana, Shorena Janelidze, Simone Baiardi, Erik Stomrud, Piero Parchi, Oskar Hansso. Cognitive effects of Lewy body pathology in clinically unimpaired individuals. Nature medicine. 2023-07-18. PMID:37464059. |
little is known about the effects of lb pathology in preclinical (presymptomatic) individuals, either as isolated pathology or coexisting with alzheimer's disease (ad) pathology (β-amyloid (aβ) and tau). |
2023-07-18 |
2023-08-14 |
human |
| Corinne Quadalti, Sebastian Palmqvist, Sara Hall, Marcello Rossi, Angela Mammana, Shorena Janelidze, Sofia Dellavalle, Niklas Mattsson-Carlgren, Simone Baiardi, Erik Stomrud, Oskar Hansson, Piero Parch. Clinical effects of Lewy body pathology in cognitively impaired individuals. Nature medicine. 2023-07-18. PMID:37464058. |
there is poor knowledge about the clinical effects of lewy body (lb) pathology in patients with cognitive impairment, especially when coexisting with alzheimer's disease (ad) pathology (amyloid-β and tau). |
2023-07-18 |
2023-08-14 |
Not clear |
| Adekunle Aina, Shawn C C Hsueh, Ebrima Gibbs, Xubiao Peng, Neil R Cashman, Steven S Plotki. De Novo Design of a β-Helix Tau Protein Scaffold: An Oligomer-Selective Vaccine Immunogen Candidate for Alzheimer's Disease. ACS chemical neuroscience. 2023-07-17. PMID:37458595. |
de novo design of a β-helix tau protein scaffold: an oligomer-selective vaccine immunogen candidate for alzheimer's disease. |
2023-07-17 |
2023-08-14 |
Not clear |
| Adekunle Aina, Shawn C C Hsueh, Ebrima Gibbs, Xubiao Peng, Neil R Cashman, Steven S Plotki. De Novo Design of a β-Helix Tau Protein Scaffold: An Oligomer-Selective Vaccine Immunogen Candidate for Alzheimer's Disease. ACS chemical neuroscience. 2023-07-17. PMID:37458595. |
tau pathology is associated with many neurodegenerative disorders, including alzheimer's disease (ad), where the spatio-temporal pattern of tau neurofibrillary tangles strongly correlates with disease progression, which motivates therapeutics selective for misfolded tau. |
2023-07-17 |
2023-08-14 |
Not clear |
| Yatong He, Ding Nan, Hongmei Wan. Role of Non-Receptor-Type Tyrosine Phosphatases in Brain-Related Diseases. Molecular neurobiology. 2023-07-17. PMID:37458988. |
these include ptpn6, ptpn11, and ptpn13, which are involved in glioma signaling; ptpn1, ptpn5, and ptpn13, which are involved in the pathogenesis of alzheimer's disease tau protein lesions, ptpn23, which may be involved in the pathogenesis of epilepsy and ptpn1, which is involved in the pathogenesis of parkinson's disease. |
2023-07-17 |
2023-08-14 |
Not clear |
| Teodora Z Markova, Claire J Ciampa, Jourdan H Parent, Molly R LaPoint, Mark D'Esposito, William J Jagust, Anne S Berr. Poorer aging trajectories are associated with elevated serotonin synthesis capacity. Molecular psychiatry. 2023-07-17. PMID:37460847. |
the dorsal raphe nucleus (drn) is one of the earliest targets of alzheimer's disease-related tau pathology and is a major source of brain serotonin. |
2023-07-17 |
2023-08-14 |
Not clear |
| Gabrielle Zuniga, Bess Fros. Selective neuronal vulnerability to deficits in RNA processing. Progress in neurobiology. 2023-07-16. PMID:37454791. |
additionally, we explore how tau, a microtubule-associated protein implicated in alzheimer's disease and related tauopathies, contributes to deficits in rna processing and clearance. |
2023-07-16 |
2023-08-14 |
Not clear |
| Cassia Overk, Emma Fiorini, Chiara Babolin, Marija Vukicevic, Catherine Morici, Rime Madani, Valerie Eligert, Marie Kosco-Vilbois, Amanda Roberts, Ann Becker, Andrea Pfeifer, William C Moble. Modeling Alzheimer's disease related phenotypes in the Ts65Dn mouse: impact of age on Aβ, Tau, pTau, NfL, and behavior. Frontiers in neuroscience. vol 17. 2023-07-15. PMID:37449271. |
modeling alzheimer's disease related phenotypes in the ts65dn mouse: impact of age on aβ, tau, ptau, nfl, and behavior. |
2023-07-15 |
2023-08-14 |
mouse |
| Marina Passero, Tianhua Zhai, Zuyi Huan. Investigation of Potential Drug Targets for Cholesterol Regulation to Treat Alzheimer's Disease. International journal of environmental research and public health. vol 20. issue 13. 2023-07-14. PMID:37444065. |
while the major hallmarks of alzheimer's disease are the accumulation of amyloid plaques and tau protein tangles, excessive accumulation of cholesterol is reportedly correlated with alzheimer's disease patients. |
2023-07-14 |
2023-08-14 |
mouse |
| Ruifeng Zhang, Miao Zeng, Xiaolu Zhang, Yujia Zheng, Nuan Lv, Luming Wang, Jiali Gan, Yawen Li, Xijuan Jiang, Lin Yan. Therapeutic Candidates for Alzheimer's Disease: Saponins. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445682. |
these studies suggest that saponins have the potential to ameliorate alzheimer's disease by reducing amyloid beta peptide deposition, inhibiting tau phosphorylation, modulating oxidative stress, reducing inflammation, and antiapoptosis. |
2023-07-14 |
2023-08-14 |
Not clear |
| Constantin Kondak, Michael Leith, Thomas C Baddeley, Renato X Santos, Charles R Harrington, Claude M Wischik, Gernot Riedel, Jochen Klei. Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445987. |
tau protein aggregations are important contributors to the etiology of alzheimer's disease (ad). |
2023-07-14 |
2023-08-14 |
mouse |