All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Chris Carte. Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System. International journal of Alzheimer's disease. vol 2011. 2012-08-23. PMID:22254144. these autoantibodies, as well as those to nerve growth factor and tau, also observed in alzheimer's disease, may well be antibodies to pathogens, due to homology between human autoantigens and pathogen proteins. 2012-08-23 2023-08-12 human
Siddhartha Mondragón-Rodríguez, George Perry, Xiongwei Zhu, Jannic Boeh. Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22482074. amyloid beta and tau proteins as therapeutic targets for alzheimer's disease treatment: rethinking the current strategy. 2012-08-23 2023-08-12 Not clear
Siddhartha Mondragón-Rodríguez, George Perry, Xiongwei Zhu, Jannic Boeh. Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22482074. alzheimer's disease (ad) is defined by the concurrence of accumulation of abnormal aggregates composed of two proteins: amyloid beta (aβ) and tau, and of cellular changes including neurite degeneration and loss of neurons and cognitive functions. 2012-08-23 2023-08-12 Not clear
Carlos Carrasco-Gallardo, Leonardo Guzmán, Ricardo B Maccion. Shilajit: a natural phytocomplex with potential procognitive activity. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22482077. thus, fulvic acid, the main active principle, blocks tau self-aggregation, opening an avenue toward the study of alzheimer's therapy. 2012-08-23 2023-08-12 human
Carole J Proctor, Douglas A Gra. A unifying hypothesis for familial and sporadic Alzheimer's disease. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22482080. alzheimer's disease (ad) is characterised by the aggregation of two quite different proteins, namely, amyloid-beta (aβ), which forms extracellular plaques, and tau, the main component of cytoplasmic neurofibrillary tangles. 2012-08-23 2023-08-12 Not clear
Mario Nizzari, Stefano Thellung, Alessandro Corsaro, Valentina Villa, Aldo Pagano, Carola Porcile, Claudio Russo, Tullio Flori. Neurodegeneration in Alzheimer disease: role of amyloid precursor protein and presenilin 1 intracellular signaling. Journal of toxicology. vol 2012. 2012-08-23. PMID:22496686. alzheimer disease (ad) is a heterogeneous neurodegenerative disorder characterized by (1) progressive loss of synapses and neurons, (2) intracellular neurofibrillary tangles, composed of hyperphosphorylated tau protein, and (3) amyloid plaques. 2012-08-23 2023-08-12 Not clear
Nicole Gallo-Payet, Marie-Odile Guimond, Lyne Bilodeau, Charlotta Wallinder, Mathias Alterman, Anders Hallber. Angiotensin II, a Neuropeptide at the Frontier between Endocrinology and Neuroscience: Is There a Link between the Angiotensin II Type 2 Receptor and Alzheimer's Disease? Frontiers in endocrinology. vol 2. 2012-08-23. PMID:22649365. amyloid-β peptide deposition, abnormal hyperphosphorylation of tau, as well as inflammation and vascular damage, are associated with the development of alzheimer's disease (ad). 2012-08-23 2023-08-12 Not clear
Jose F Abisambra, Umesh K Jinwal, Jeffrey R Jones, Laura J Blair, John Koren, Chad A Dicke. Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics. Current neuropharmacology. vol 9. issue 4. 2012-08-23. PMID:22654720. in alzheimer's disease, extracellular accumulation of the amyloid β peptide (aβ) and intracellular aggregation of the microtubule associated protein tau may result from mechanisms involving chaperone proteins like the hsps. 2012-08-23 2023-08-12 Not clear
Sergio A Rosales-Corral, Gabriela Lopez-Armas, Jose Cruz-Ramos, Valery G Melnikov, Dun-Xian Tan, Lucien C Manchester, Ruben Munoz, Russel J Reite. Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-β: A Protective Role of Melatonin. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22666620. alzheimer pathogenesis involves mitochondrial dysfunction, which is closely related to amyloid-β (aβ) generation, abnormal tau phosphorylation, oxidative stress, and apoptosis. 2012-08-23 2023-08-12 rat
Michala Kolarova, Francisco García-Sierra, Ales Bartos, Jan Ricny, Daniela Ripov. Structure and pathology of tau protein in Alzheimer disease. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22690349. structure and pathology of tau protein in alzheimer disease. 2012-08-23 2023-08-12 human
Marc Gistelinck, Jean-Charles Lambert, Patrick Callaerts, Bart Dermaut, Pierre Dourle. Drosophila models of tauopathies: what have we learned? International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22701808. aggregates of the microtubule-associated protein tau are neuropathological hallmark lesions in alzheimer's disease (ad) and related primary tauopathies. 2012-08-23 2023-08-12 mouse
Natalia Crespo-Biel, Clara Theunis, Fred Van Leuve. Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22720188. protein tau: prime cause of synaptic and neuronal degeneration in alzheimer's disease. 2012-08-23 2023-08-12 human
Sébastien S Hébert, Nicolas Sergeant, Luc Bué. MicroRNAs and the Regulation of Tau Metabolism. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22720189. abnormal regulation of tau phosphorylation and/or alternative splicing is associated with the development of a large (>20) group of neurodegenerative disorders collectively known as tauopathies, the most common being alzheimer's disease. 2012-08-23 2023-08-12 mouse
Yazi D Ke, Alexandra K Suchowerska, Julia van der Hoven, Dineeka M De Silva, Christopher W Wu, Janet van Eersel, Arne Ittner, Lars M Ittne. Lessons from tau-deficient mice. International journal of Alzheimer's disease. vol 2012. 2012-08-23. PMID:22720190. both alzheimer's disease (ad) and frontotemporal dementia (ftd) are characterized by the deposition of hyperphosphorylated forms of the microtubule-associated protein tau in neurons and/or glia. 2012-08-23 2023-08-12 mouse
Nadia Canu, Ilaria Filesi, Andrea Pristerà, Maria Teresa Ciotti, Silvia Biocc. Altered intracellular distribution of PrPC and impairment of proteasome activity in tau overexpressing cortical neurons. Journal of Alzheimer's disease : JAD. vol 27. issue 3. 2012-08-20. PMID:21841253. the microtubule associated protein tau plays a crucial role in alzheimer's disease and in many neurodegenerative disorders collectively known as tauopathies. 2012-08-20 2023-08-12 Not clear
Nikolai N Sluchanko, Nikolai B Guse. Probable participation of 14-3-3 in tau protein oligomerization and aggregation. Journal of Alzheimer's disease : JAD. vol 27. issue 3. 2012-08-20. PMID:21876254. aggregation of tau proteins followed by formation of paired helical filaments and neurofibrillary tangles is considered as a hallmark of certain neurodegenerative disorders such as different tauopathies and alzheimer's disease (ad). 2012-08-20 2023-08-12 human
Najla Kfoury, Brandon B Holmes, Hong Jiang, David M Holtzman, Marc I Diamon. Trans-cellular propagation of Tau aggregation by fibrillar species. The Journal of biological chemistry. vol 287. issue 23. 2012-08-20. PMID:22461630. aggregation of the microtubule associated protein tau is associated with several neurodegenerative disorders, including alzheimer disease and frontotemporal dementia. 2012-08-20 2023-08-12 Not clear
Najla Kfoury, Brandon B Holmes, Hong Jiang, David M Holtzman, Marc I Diamon. Trans-cellular propagation of Tau aggregation by fibrillar species. The Journal of biological chemistry. vol 287. issue 23. 2012-08-20. PMID:22461630. in alzheimer disease, tau pathology spreads progressively throughout the brain, possibly along existing neural networks. 2012-08-20 2023-08-12 Not clear
José L Molinuevo, Juan D Gispert, Jesús Pujol, Santiago Rojas, Albert Lladó, Mircea Balasa, Anna Antonell, Raquel Sánchez-Valle, Lorena Ram. [A new approach to the Alzheimer's disease diagnosis with biomarkers: description of the AD-CSF-Index]. Revista de neurologia. vol 54. issue 9. 2012-08-20. PMID:22532214. studies with cerebrospinal fluid (csf) biomarkers in patients with confirmed alzheimer's disease (ad) pathology have shown that decreased levels of abeta(1-42) and increased levels of tau and p-tau, are a specific feature of the ad type pathology. 2012-08-20 2023-08-12 Not clear
Julia Miralbell, Gabriela Spulber, Babak Hooshmand, Ariadna Besga, Maria Mataró, Angel Cedazo-Minguez, Miia Kivipelto, Lars-Olof Wahlun. Grey matter and cognitive patterns in cognitive impaired subjects using CSF biomarker cut-offs. Journal of Alzheimer's disease : JAD. vol 29. issue 4. 2012-08-17. PMID:22330819. patients with abnormal levels of csf tau (but not aβ1-42) showed an alzheimer's disease-like pattern for both gm distribution and cognitive profile, compared to those with normal levels. 2012-08-17 2023-08-12 human