| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Felix Langerscheidt, Tamara Wied, Mohamed Aghyad Al Kabbani, Thilo van Eimeren, Gilbert Wunderlich, Hans Zempe. Genetic forms of tauopathies: inherited causes and implications of Alzheimer's disease-like TAU pathology in primary and secondary tauopathies. Journal of neurology. 2024-03-30. PMID:38554150. |
mapt-associated frontotemporal dementia (ftd), progressive supranuclear palsy (psp), corticobasal degeneration (cbd), and alzheimer's disease (ad)) tau is recognized as a significant pathogenic driver of the disease. |
2024-03-30 |
2024-04-02 |
Not clear |
| Jiehui Jiang, Rong Shi, Jiaying Lu, Min Wang, Qi Zhang, Shuoyan Zhang, Luyao Wang, Ian Alberts, Axel Rominger, Chuantao Zuo, Kuangyu Sh. Detection of individual brain tau deposition in Alzheimer's disease based on latent feature-enhanced generative adversarial network. NeuroImage. 2024-03-30. PMID:38554780. |
detection of individual brain tau deposition in alzheimer's disease based on latent feature-enhanced generative adversarial network. |
2024-03-30 |
2024-04-02 |
Not clear |
| Jiehui Jiang, Rong Shi, Jiaying Lu, Min Wang, Qi Zhang, Shuoyan Zhang, Luyao Wang, Ian Alberts, Axel Rominger, Chuantao Zuo, Kuangyu Sh. Detection of individual brain tau deposition in Alzheimer's disease based on latent feature-enhanced generative adversarial network. NeuroImage. 2024-03-30. PMID:38554780. |
the conventional methods for interpreting tau pet imaging in alzheimer's disease (ad), including visual assessment and semi-quantitative analysis of fixed hallmark regions, are insensitive to detect individual small lesions because of the spatiotemporal neuropathology's heterogeneity. |
2024-03-30 |
2024-04-02 |
Not clear |
| Masumi Sugiyama, Kenneth S Kosik, Eleni Panagioto. Mathematical topology and geometry-based classification of tauopathies. Scientific reports. vol 14. issue 1. 2024-03-30. PMID:38555402. |
neurodegenerative diseases, like alzheimer's, are associated with the presence of neurofibrillary lesions formed by tau protein filaments in the cerebral cortex. |
2024-03-30 |
2024-04-02 |
Not clear |
| Robert W B Lov. Aniracetam: An Evidence-Based Model for Preventing the Accumulation of Amyloid-β Plaques in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2024-03-29. PMID:38552113. |
alzheimer's disease is characterized by the accumulation of amyloid-β plaques (aβ), an increase in tau protein neurofibrillary tangles, and a loss of synapses. |
2024-03-29 |
2024-04-01 |
human |
| Seyed Hani Hojjati, Gloria C Chiang, Tracy A Butler, Mony de Leon, Ajay Gupta, Yi Li, Mert R Sabuncu, Farnia Feiz, Siddharth Nayak, Jacob Shteingart, Sindy Ozoria, Saman Gholipour Picha, Yaakov Stern, José A Luchsinger, Davangere P Devanand, Qolamreza R Razligh. Remote Associations Between Tau and Cortical Amyloid-β Are Stage-Dependent. Journal of Alzheimer's disease : JAD. 2024-03-29. PMID:38552116. |
histopathologic studies of alzheimer's disease (ad) suggest that extracellular amyloid-β (aβ) plaques promote the spread of neurofibrillary tau tangles. |
2024-03-29 |
2024-04-01 |
Not clear |
| Stephanie Doering, Austin McCullough, Brian A Gordon, Charles D Chen, Nicole McKay, Diana Hobbs, Sarah Keefe, Shaney Flores, Jalen Scott, Hunter Smith, Stephen Jarman, Kelley Jackson, Russ C Hornbeck, Beau M Ances, Chengjie Xiong, Andrew J Aschenbrenner, Jason Hassenstab, Carlos Cruchaga, Alisha Daniels, Randall J Bateman, John C Morris, Tammie L S Benzinge. Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging. EBioMedicine. vol 103. 2024-03-29. PMID:38552342. |
deconstructing pathological tau by biological process in early stages of alzheimer disease: a method for quantifying tau spatial spread in neuroimaging. |
2024-03-29 |
2024-04-01 |
Not clear |
| Stephanie Doering, Austin McCullough, Brian A Gordon, Charles D Chen, Nicole McKay, Diana Hobbs, Sarah Keefe, Shaney Flores, Jalen Scott, Hunter Smith, Stephen Jarman, Kelley Jackson, Russ C Hornbeck, Beau M Ances, Chengjie Xiong, Andrew J Aschenbrenner, Jason Hassenstab, Carlos Cruchaga, Alisha Daniels, Randall J Bateman, John C Morris, Tammie L S Benzinge. Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging. EBioMedicine. vol 103. 2024-03-29. PMID:38552342. |
neuroimaging studies often quantify tau burden in standardized brain regions to assess alzheimer disease (ad) progression. |
2024-03-29 |
2024-04-01 |
Not clear |
| Margrethe A Olesen, Eugenia Pradenas, Francisca Villavicencio-Tejo, George A Porter, Gail V W Johnson, Rodrigo A Quintanill. Mitochondria-tau association promotes cognitive decline and hippocampal bioenergetic deficits during the aging. Free radical biology & medicine. 2024-03-29. PMID:38552927. |
we previously showed that caspase-3 cleaved tau, a relevant tau form in alzheimer's disease (ad), affects mitochondrial bioenergetics, dynamics and synaptic plasticity by the opening of mitochondrial permeability transition pore (mptp). |
2024-03-29 |
2024-04-01 |
mouse |
| b' Dominika Ole\\xc5\\xa1ov\\xc3\\xa1, Dana Dobe\\xc5\\xa1ov\\xc3\\xa1, Petra Majerov\\xc3\\xa1, Radana Brumarov\\xc3\\xa1, Ale\\xc5\\xa1 Kvasni\\xc4\\x8dka, \\xc5\\xa0t\\xc4\\x9bp\\xc3\\xa1n Kou\\xc5\\x99il, Eva Stevens, Jozef Hanes, \\xc4\\xbdubica Fialov\\xc3\\xa1, Alena Michalicov\\xc3\\xa1, Juraj Pie\\xc5\\xa1\\xc5\\xa5ansk\\xc3\\xbd, Jakub \\xc5\\xa0insk\\xc3\\xbd, Petr Ka\\xc5\\x88ovsk\\xc3\\xbd, David Friedeck\\xc3\\xbd, Andrej Kov\\xc3\\xa1\\xc4\\x8. Changes in lipid metabolism track with the progression of neurofibrillary pathology in tauopathies. Journal of neuroinflammation. vol 21. issue 1. 2024-03-28. PMID:38539208.' |
accumulation of tau leads to neuroinflammation and neuronal cell death in tauopathies, including alzheimer's disease. |
2024-03-28 |
2024-03-30 |
Not clear |
| Susana Junceda, María Cruz-Alonso, Beatriz Fernandez, Rosario Pereiro, Eva Martínez-Pinilla, Ana Navarr. Iron Dysregulation in Alzheimer's Disease: LA-ICP-MS Bioimaging of the Distribution of Iron and Ferroportin in the CA1 Region of the Human Hippocampus. Biomolecules. vol 14. issue 3. 2024-03-28. PMID:38540715. |
alzheimer's disease (ad) is a prevalent neurodegenerative disorder characterized by cognitive decline and neuropathological hallmarks, including β-amyloid (aβ) plaques, tau tangles, synaptic dysfunction and neurodegeneration. |
2024-03-28 |
2024-03-30 |
human |
| Ryszard Pluta, Stanisław J Czuczwa. International journal of molecular sciences. vol 25. issue 6. 2024-03-28. PMID:38542064. |
the phenomenon of tau protein hyperphosphorylation is a similar pathological feature of both post-ischemic brain injury and alzheimer's disease. |
2024-03-28 |
2024-03-30 |
Not clear |
| Ryszard Pluta, Stanisław J Czuczwa. International journal of molecular sciences. vol 25. issue 6. 2024-03-28. PMID:38542064. |
in alzheimer's disease, the phosphorylated thr231 motif in tau protein has two distinct |
2024-03-28 |
2024-03-30 |
Not clear |
| Retraction: 5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease. Annals of neurology. 2024-03-28. PMID:38546184. |
retraction: 5-lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease. |
2024-03-28 |
2024-03-30 |
mouse |
| Retraction: 5-Lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease. Annals of neurology. 2024-03-28. PMID:38546184. |
retraction: jin chu, phillip f. giannopoulos, carolina ceballos-diaz, todd e. golde, domenico pratico (2012), 5-lipoxygenase gene transfer worsens memory, amyloid, and tau brain pathologies in a mouse model of alzheimer disease. |
2024-03-28 |
2024-03-30 |
mouse |
| Kiwamu Kudo, Kamalini G Ranasinghe, Hirofumi Morise, Faatimah Syed, Kensuke Sekihara, Katherine P Rankin, Bruce L Miller, Joel H Kramer, Gil D Rabinovici, Keith Vossel, Heidi E Kirsch, Srikantan S Nagaraja. Neurophysiological trajectories in Alzheimer's disease progression. eLife. vol 12. 2024-03-28. PMID:38546337. |
alzheimer's disease (ad) is characterized by the accumulation of amyloid-β and misfolded tau proteins causing synaptic dysfunction, and progressive neurodegeneration and cognitive decline. |
2024-03-28 |
2024-03-30 |
Not clear |
| Benjamin C Creekmore, Kathryn Kixmoeller, Ben E Black, Edward B Lee, Yi-Wei Chan. Ultrastructure of human brain tissue vitrified from autopsy revealed by cryo-ET with cryo-plasma FIB milling. Nature communications. vol 15. issue 1. 2024-03-27. PMID:38531877. |
lamellae generated in alzheimer's disease brain tissue reveal intact subcellular structures including components of autophagy and potential pathologic tau fibrils. |
2024-03-27 |
2024-03-29 |
human |
| Soheil Saghafi, Timothy Rumbell, Viatcheslav Gurev, James Kozloski, Francesco Tamagnini, Kyle C A Wedgwood, Casey O Diekma. Inferring Parameters of Pyramidal Neuron Excitability in Mouse Models of Alzheimer's Disease Using Biophysical Modeling and Deep Learning. Bulletin of mathematical biology. vol 86. issue 5. 2024-03-26. PMID:38528167. |
alzheimer's disease (ad) is believed to occur when abnormal amounts of the proteins amyloid beta and tau aggregate in the brain, resulting in a progressive loss of neuronal function. |
2024-03-26 |
2024-03-28 |
mouse |
| Nickolay K Isaev, Elizaveta E Genrikhs, Elena V Stelmashoo. Methylene blue and its potential in the treatment of traumatic brain injury, brain ischemia, and Alzheimer's disease. Reviews in the neurosciences. 2024-03-26. PMID:38530227. |
in this case, the long-term neurodegeneration of the brain is similar to the neurodegeneration characteristic of alzheimer's disease (ad) and is associated with the accumulation of beta amyloid and tau protein. |
2024-03-26 |
2024-03-28 |
Not clear |
| Gourav Singh, Gauri Shankar, Samir Ranjan Panda, Sunil Kumar, Sanskriti Rai, Himanshu Verma, Prabhat Kumar, Prasanta Kumar Nayak, V G M Naidu, Saripella Srikrishna, Saroj Kumar, Gyan Mod. Design, Synthesis, and Biological Evaluation of Ferulic Acid Template-Based Novel Multifunctional Ligands Targeting NLRP3 Inflammasome for the Management of Alzheimer's Disease. ACS chemical neuroscience. 2024-03-25. PMID:38525886. |
alzheimer's disease (ad) is the most common cause of dementia, which arises due to low levels of acetyl and butyrylcholines, an increase in oxidative stress, inflammation, metal dyshomeostasis, aβ and tau aggregations. |
2024-03-25 |
2024-03-27 |
Not clear |