All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Chan Chen, Ramhari Kumbhar, Hu Wang, Xiuli Yang, Kundlik Gadhave, Cyrus Rastegar, Yasuyoshi Kimura, Adam Behensky, Sruthi Katakam, Deok Jeong, Liang Wang, Anthony Wang, Rong Chen, Shu Zhang, Lingtao Jin, Creg J Workman, Dario A A Vignali, Olga Pletinkova, David W Nauen, Philip C Wong, Juan C Troncoso, Mingyao Ying, Valina L Dawson, Ted M Dawson, Xiaobo Ma. Pathological Tau transmission initiated by binding lymphocyte-activation gene 3. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37293032. accumulated tangles of filamentous tau protein are considered pathogenic lesions of alzheimer's disease (ad) and related tauopathies, including progressive supranuclear palsy, and corticobasal degeneration. 2023-06-09 2023-08-14 Not clear
Monika Arbaciauskaite, Azady Pirhanov, Erik Ammermann, Yu Lei, Yong Ku Ch. Yeast biopanning against site-specific phosphorylations in tau. Protein engineering, design & selection : PEDS. 2023-06-09. PMID:37294629. the detection of site-specific phosphorylation in the microtubule-associated protein tau is emerging as a means to diagnose and monitor the progression of alzheimer's disease (ad) as well as other neurodegenerative diseases. 2023-06-09 2023-08-14 Not clear
Houfang Long, Shuyi Zeng, Yunpeng Sun, Cong Li. Biochemical and biophysical characterization of pathological aggregation of amyloid proteins. Biophysics reports. vol 8. issue 1. 2023-06-08. PMID:37287686. several amyloid proteins including α-synuclein (α-syn), tau, amyloid β (aβ) protein, and tar dna-binding protein 43 kda (tdp-43) form pathological fibrils and deposit in patient brains of different neurodegenerative diseases (nds) such as parkinson's disease (pd), alzheimer's disease (ad) and amyotrophic lateral sclerosis (als). 2023-06-08 2023-08-14 human
Seong Soo A An, John P Hulm. Plasma amyloid-beta oligomer and phosphorylated tau: diagnostic tools for progressive Alzheimer's disease. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282463. plasma amyloid-beta oligomer and phosphorylated tau: diagnostic tools for progressive alzheimer's disease. 2023-06-07 2023-08-14 Not clear
Chin-Tong On. Enrichment of novel Tau isoform with altered biochemical properties in Alzheimer's disease. Neural regeneration research. vol 18. issue 11. 2023-06-07. PMID:37282466. enrichment of novel tau isoform with altered biochemical properties in alzheimer's disease. 2023-06-07 2023-08-14 Not clear
Kurt A Jellinge. Neuropathology of the Alzheimer's continuum: an update. Free neuropathology. vol 1. 2023-06-07. PMID:37283686. alzheimer's disease (ad), the most common form of dementia worldwide, is a mixed proteinopathy (amyloid and tau). 2023-06-07 2023-08-14 Not clear
David S Priemer, Daniel P Per. Neurotrauma: 2022 update. Free neuropathology. vol 3. 2023-06-07. PMID:37284155. next, a critical new study has identified that acetylated tau protein, which has been found to be increased in the brains of alzheimer's disease and cte patients, can be induced by tbi, is neurotoxic, and that its reduction via already-existent therapeutics is neuroprotective. 2023-06-07 2023-08-14 Not clear
Daniel P Per. Neurotrauma: 2021 update. Free neuropathology. vol 2. 2023-06-07. PMID:37284617. important new data on the nature and distribution of tau involvement of neurons and astrocytes in cases of chronic traumatic encephalopathy (cte) also appeared suggesting differences and similarities to alzheimer s disease. 2023-06-07 2023-08-14 Not clear
John F Crar. Neurodegeneration: 2021 update. Free neuropathology. vol 2. 2023-06-07. PMID:37284623. the onslaught of transcriptomic studies has begun to give way to proteomics, with three transformative studies published examining glial contributions to alzheimer disease, cerebral atherosclerosis in cognitive decline, and the complex sequence of post-translational modifications of the tau protein. 2023-06-07 2023-08-14 Not clear
John F Crar. Neurodegeneration: 2021 update. Free neuropathology. vol 2. 2023-06-07. PMID:37284623. plasma biomarkers for alzheimer disease have continued to make rapid advances, especially around highly sensitive assays capable of detecting different forms of abnormal hyperphosphorylated tau in peripheral blood. 2023-06-07 2023-08-14 Not clear
Michael R Holden, Brad J Krzesinski, Hilary A Weismiller, Justin R Shady, Martin Margitta. MAP2 caps tau fibrils and inhibits aggregation. The Journal of biological chemistry. 2023-06-07. PMID:37286038. fibrils of the microtubule associated protein tau are intimately linked to the pathology of alzheimer's disease (ad) and related neurodegenerative disorders. 2023-06-07 2023-08-14 human
Clara Vila-Castelar, Yinghua Chen, Stephanie Langella, Francisco Lopera, Henrik Zetterberg, Oskar Hansson, Jeffrey L Dage, Shorena Janelidzde, Yi Su, Kewei Chen, Celina Pluim McDowell, Jairo E Martinez, Liliana Ramirez-Gomez, Gloria Garcia, David Aguillon, Ana Baena, Margarita Giraldo-Chica, Hillary D Protas, Valentina Ghisays, Silvia Rios-Romenets, Pierre N Tariot, Kaj Blennow, Eric M Reiman, Yakeel T Quiro. Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-06-06. PMID:37279390. plasma tau phosphorylated at threonine 217 (p-tau217) and neurofilament light (nfl) have emerged as markers of alzheimer's disease (ad) pathology. 2023-06-06 2023-08-14 Not clear
Deborah N Schoonhoven, Emma M Coomans, Ana P Millán, Anne M van Nifterick, Denise Visser, Rik Ossenkoppele, Hayel Tuncel, Wiesje M van der Flier, Sandeep S V Golla, Philip Scheltens, Arjan Hillebrand, Bart N M van Berckel, Cornelis J Stam, Alida A Gou. Tau protein spreads through functionally connected neurons in Alzheimer's disease: a combined MEG/PET study. Brain : a journal of neurology. 2023-06-06. PMID:37279597. tau protein spreads through functionally connected neurons in alzheimer's disease: a combined meg/pet study. 2023-06-06 2023-08-14 human
Deborah N Schoonhoven, Emma M Coomans, Ana P Millán, Anne M van Nifterick, Denise Visser, Rik Ossenkoppele, Hayel Tuncel, Wiesje M van der Flier, Sandeep S V Golla, Philip Scheltens, Arjan Hillebrand, Bart N M van Berckel, Cornelis J Stam, Alida A Gou. Tau protein spreads through functionally connected neurons in Alzheimer's disease: a combined MEG/PET study. Brain : a journal of neurology. 2023-06-06. PMID:37279597. recent studies on alzheimer's disease (ad) suggest that tau proteins spread through the brain following neuronal connections. 2023-06-06 2023-08-14 human
Tehniat Faraz Ahmed, Muhammad Bilal Azmi, Fauzia Imtiaz, Uzma Zaman, Affan Ahmed, Naila Shahba. Plasma levels of phosphorylated tau and neurofilament light chain as potential biomarkers for Alzheimer's disease: A biochemical analysis in Pakistani population. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 31. issue 7. 2023-06-05. PMID:37273267. plasma levels of phosphorylated tau and neurofilament light chain as potential biomarkers for alzheimer's disease: a biochemical analysis in pakistani population. 2023-06-05 2023-08-14 human
Tehniat Faraz Ahmed, Muhammad Bilal Azmi, Fauzia Imtiaz, Uzma Zaman, Affan Ahmed, Naila Shahba. Plasma levels of phosphorylated tau and neurofilament light chain as potential biomarkers for Alzheimer's disease: A biochemical analysis in Pakistani population. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 31. issue 7. 2023-06-05. PMID:37273267. we looked at the plasma levels of amyloid beta-42 (aβ-42), phosphorylated tau (p-tau), and neurofilament light (nfl) in patients with alzheimer's clinical syndrome (acs) and healthy controls (hc) from the pakistani population to keep pace with the global efforts towards establishing accessible and affordable biochemical diagnostic markers for ad in pakistan. 2023-06-05 2023-08-14 human
Stefania Santarelli, Chiara Londero, Alessia Soldano, Carlotta Candelaresi, Leonardo Todeschini, Luisa Vernizzi, Paola Bellost. Frontiers in neuroscience. vol 17. 2023-06-05. PMID:37274187. indeed, despite the physiological and morphological differences between the fly and the human brain, most of the biochemical and molecular aspects regulating protein homeostasis, including autophagy, are conserved between the two species.in this review, we will provide an overview of the most common neurodegenerative proteinopathies, which include polyq diseases (huntington's disease, spinocerebellar ataxia 1, 2, and 3), amyotrophic lateral sclerosis (c9orf72, sod1, tdp-43, fus), alzheimer's disease (app, tau) parkinson's disease (a-syn, parkin and pink1, lrrk2) and prion diseases, highlighting the studies using drosophila that have contributed to understanding the conserved mechanisms and elucidating the role of autophagy in these diseases. 2023-06-05 2023-08-14 human
Garrett S Gibbons, Hailey Gould, Virginia M-Y Lee, Alex Crowe, Kurt R Brunde. Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model. The Journal of biological chemistry. 2023-06-03. PMID:37269953. alzheimer's disease (ad) is characterized by the presence of tau protein inclusions and amyloid beta (aβ) plaques in the brain, with aβ peptides generated by cleavage of the amyloid precursor protein (app) by bace1 and γ-secretase. 2023-06-03 2023-08-14 human
Taha Alqahtani, Sharada L Deore, Anjali A Kide, Bhavana A Shende, Ritika Sharma, Rita Dadarao Chakole, Lalita S Nemade, Nikita Kishor Kale, Sudarshana Borah, Savita Shrikant Deokar, Ashok Behera, Divya Dhawal Bhandari, Nikita Gaikwad, Abul Kalam Azad, Arabinda Ghos. Mitochondrial dysfunction and oxidative stress in Alzheimer's disease, and Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis -An updated review. Mitochondrion. 2023-06-03. PMID:37269968. amyloid-ß and tau problems both have an effect on mitochondria, which leads to mitochondrial malfunction and, ultimately, the onset of alzheimer's disease. 2023-06-03 2023-08-14 Not clear
Kai Sin Chin, Leonid Churilov, Vincent Doré, Victor L Villemagne, Christopher C Rowe, Nawaf Yassi, Rosie Watso. Tau in dementia with Lewy bodies. The Australian and New Zealand journal of psychiatry. 2023-06-02. PMID:37264610. recent advances in biomarkers for alzheimer's disease include second-generation tau positron emission tomography as well as the detection of phosphorylated tau at threonine 181 (p-tau181) in plasma. 2023-06-02 2023-08-14 Not clear