All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Seung-Yong Yoon, Jeong-Su Park, Jung-Eun Choi, Jin-Myung Choi, Woo-Je Lee, Seong-Who Kim, Dong-Hou Ki. Rosiglitazone reduces tau phosphorylation via JNK inhibition in the hippocampus of rats with type 2 diabetes and tau transfected SH-SY5Y cells. Neurobiology of disease. vol 40. issue 2. 2011-01-12. PMID:20655383. hence, rosiglitazone could be used in reducing tau phosphorylation through jnk inactivation for therapeutic effects in type 2 diabetes related alzheimer's disease. 2011-01-12 2023-08-12 mouse
Iain C Anthony, Katherine E Norrby, Tommy Dingwall, Frances W Carnie, Tracey Millar, Juan Carlos Arango, Roy Robertson, Jeanne E Bel. Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers. Brain : a journal of neurology. vol 133. issue Pt 12. 2011-01-07. PMID:21126996. the present quantitative study of hyperphosphorylated tau and beta amyloid in drug user brains allows comparison with the related pathology in alzheimer's disease. 2011-01-07 2023-08-12 human
Iain C Anthony, Katherine E Norrby, Tommy Dingwall, Frances W Carnie, Tracey Millar, Juan Carlos Arango, Roy Robertson, Jeanne E Bel. Predisposition to accelerated Alzheimer-related changes in the brains of human immunodeficiency virus negative opiate abusers. Brain : a journal of neurology. vol 133. issue Pt 12. 2011-01-07. PMID:21126996. the levels of hyperphosphorylated tau in drug users fell far short of those seen in alzheimer's disease but overlapped with those in elderly controls. 2011-01-07 2023-08-12 human
Xiumei Huang, Yaomin Chen, Wu-Bo Li, Stanley N Cohen, Francesca-Fang Liao, Limin Li, Huaxi Xu, Yun-Wu Zhan. The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's beta-amyloid level and tau phosphorylation. Human molecular genetics. vol 19. issue 19. 2011-01-04. PMID:20650958. the rps23rg gene family originated through retroposition of the ribosomal protein s23 mrna and encodes proteins that decrease alzheimer's beta-amyloid level and tau phosphorylation. 2011-01-04 2023-08-12 mouse
Xiumei Huang, Yaomin Chen, Wu-Bo Li, Stanley N Cohen, Francesca-Fang Liao, Limin Li, Huaxi Xu, Yun-Wu Zhan. The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's beta-amyloid level and tau phosphorylation. Human molecular genetics. vol 19. issue 19. 2011-01-04. PMID:20650958. we recently identified a mouse gene, rps23 retroposed gene 1 (rps23rg1), that regulates beta-amyloid (abeta) level and tau phosphorylation, two major pathological hallmarks of alzheimer's disease (ad), and found that rps23rg1 originated through retroposition of the mouse ribosomal protein s23 (rps23) mrna. 2011-01-04 2023-08-12 mouse
Nelleke Tolboom, Esther L G E Koedam, Jonathan M Schott, Maqsood Yaqub, Marinus A Blankenstein, Frederik Barkhof, Yolande A L Pijnenburg, Adriaan A Lammertsma, Philip Scheltens, Bart N M van Bercke. Dementia mimicking Alzheimer's disease Owing to a tau mutation: CSF and PET findings. Alzheimer disease and associated disorders. vol 24. issue 3. 2011-01-04. PMID:20683187. dementia mimicking alzheimer's disease owing to a tau mutation: csf and pet findings. 2011-01-04 2023-08-12 Not clear
Oyinkan Sofola, Fiona Kerr, Iain Rogers, Richard Killick, Hrvoje Augustin, Carina Gandy, Marcus J Allen, John Hardy, Simon Lovestone, Linda Partridg. Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease. PLoS genetics. vol 6. issue 9. 2011-01-04. PMID:20824130. abeta peptide accumulation is thought to be the primary event in the pathogenesis of alzheimer's disease (ad), with downstream neurotoxic effects including the hyperphosphorylation of tau protein. 2011-01-04 2023-08-12 drosophila_melanogaster
K Bhaskar, G A Hobbs, S-H Yen, G Le. Tyrosine phosphorylation of tau accompanies disease progression in transgenic mouse models of tauopathy. Neuropathology and applied neurobiology. vol 36. issue 6. 2011-01-03. PMID:20609109. tau protein is a prominent component of paired helical filaments in alzheimer's disease (ad) and other tauopathies. 2011-01-03 2023-08-12 mouse
Tetsuya Kimura, Tetsuya Fukuda, Naruhiko Sahara, Shunji Yamashita, Miyuki Murayama, Tatsuya Mizoroki, Yuji Yoshiike, Boyoung Lee, Ioannis Sotiropoulos, Sumihiro Maeda, Akihiko Takashim. Aggregation of detergent-insoluble tau is involved in neuronal loss but not in synaptic loss. The Journal of biological chemistry. vol 285. issue 49. 2010-12-30. PMID:20921222. neurofibrillary tangles (nfts), which consist of highly phosphorylated tau, are hallmarks of neurodegenerative diseases including alzheimer disease (ad). 2010-12-30 2023-08-12 mouse
Ayisha Siddiqua, Martin Margitta. Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease. The Journal of biological chemistry. vol 285. issue 48. 2010-12-30. PMID:20921227. three- and four-repeat tau coassemble into heterogeneous filaments: an implication for alzheimer disease. 2010-12-30 2023-08-12 human
Ayisha Siddiqua, Martin Margitta. Three- and four-repeat Tau coassemble into heterogeneous filaments: an implication for Alzheimer disease. The Journal of biological chemistry. vol 285. issue 48. 2010-12-30. PMID:20921227. tau filaments are the pathological hallmark of numerous neurodegenerative diseases including alzheimer disease, pick disease, and progressive supranuclear palsy. 2010-12-30 2023-08-12 human
Cristian A Lasagna-Reeves, Diana L Castillo-Carranza, Marcos J Guerrero-Muoz, George R Jackson, Rakez Kaye. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. vol 49. issue 47. 2010-12-30. PMID:21047142. tau aggregation is a pathological hallmark of alzheimer's disease, parkinson's disease, and many other neurodegenerative disorders known as tauopathies. 2010-12-30 2023-08-12 Not clear
Cristian A Lasagna-Reeves, Diana L Castillo-Carranza, Marcos J Guerrero-Muoz, George R Jackson, Rakez Kaye. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. vol 49. issue 47. 2010-12-30. PMID:21047142. recently, tau oligomers have emerged as the pathogenic species in tauopathies and a possible mediator of amyloid-β toxicity in alzheimer's disease. 2010-12-30 2023-08-12 Not clear
Meredith N Braskie, Andrea D Klunder, Kiralee M Hayashi, Hillary Protas, Vladimir Kepe, Karen J Miller, S-C Huang, Jorge R Barrio, Linda M Ercoli, Prabha Siddarth, Nagichettiar Satyamurthy, Jie Liu, Arthur W Toga, Susan Y Bookheimer, Gary W Small, Paul M Thompso. Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease. Neurobiology of aging. vol 31. issue 10. 2010-12-23. PMID:19004525. amyloid plaques and tau neurofibrillary tangles, the pathological hallmarks of alzheimer's disease (ad), begin accumulating in the healthy human brain decades before clinical dementia symptoms can be detected. 2010-12-23 2023-08-12 human
Masood Kamali-Moghaddam, Frida Ekholm Pettersson, Di Wu, Hillevi Englund, Spyros Darmanis, Anna Lord, Gholamreza Tavoosidana, Dag Sehlin, Sigrun Gustafsdottir, Lars N G Nilsson, Lars Lannfelt, Ulf Landegre. Sensitive detection of Aβ protofibrils by proximity ligation--relevance for Alzheimer's disease. BMC neuroscience. vol 11. 2010-12-23. PMID:20923550. for instance, insoluble aggregates of phosphorylated tau and of aβ peptides are cornerstones in the pathology of alzheimer's disease. 2010-12-23 2023-08-12 Not clear
Sergey Larionov, Przemyslaw Wielgat, Yiner Wang, Dietmar Rudolf Thal, Harald Neuman. Spatially pathogenic forms of tau detected in Alzheimer's disease brain tissue by fluorescence lifetime-based Förster resonance energy transfer. Journal of neuroscience methods. vol 192. issue 1. 2010-12-21. PMID:20655329. spatially pathogenic forms of tau detected in alzheimer's disease brain tissue by fluorescence lifetime-based förster resonance energy transfer. 2010-12-21 2023-08-12 human
Sergey Larionov, Przemyslaw Wielgat, Yiner Wang, Dietmar Rudolf Thal, Harald Neuman. Spatially pathogenic forms of tau detected in Alzheimer's disease brain tissue by fluorescence lifetime-based Förster resonance energy transfer. Journal of neuroscience methods. vol 192. issue 1. 2010-12-21. PMID:20655329. in tauopathies including alzheimer's disease (ad) tau molecules have lost their normal spatial distance to each other and appear in oligomeric or aggregated forms. 2010-12-21 2023-08-12 human
Johan Sundelöf, Johan Sundström, Oskar Hansson, Maria Eriksdotter-Jönhagen, Vilmantas Giedraitis, Anders Larsson, Malin Degerman-Gunnarsson, Martin Ingelsson, Lennart Minthon, Kaj Blennow, Lena Kilander, Hans Basun, Lars Lannfel. Cystatin C levels are positively correlated with both Abeta42 and tau levels in cerebrospinal fluid in persons with Alzheimer's disease, mild cognitive impairment, and healthy controls. Journal of Alzheimer's disease : JAD. vol 21. issue 2. 2010-12-20. PMID:20555147. cystatin c levels are positively correlated with both abeta42 and tau levels in cerebrospinal fluid in persons with alzheimer's disease, mild cognitive impairment, and healthy controls. 2010-12-20 2023-08-12 human
Jeroen J J van Eijk, Bart van Everbroeck, W Farid Abdo, Berry P H Kremer, Marcel M Verbee. CSF neurofilament proteins levels are elevated in sporadic Creutzfeldt-Jakob disease. Journal of Alzheimer's disease : JAD. vol 21. issue 2. 2010-12-20. PMID:20555148. in this study we investigated the cerebrospinal fluid (csf) levels of neurofilament light (nfl) and heavy chain (nfhp35), total tau (t-tau), and glial fibrillary acidic protein (gfap) to detect disease specific profiles in sporadic creutzfeldt jakob disease (scjd) patients and alzheimer's disease (ad) patients. 2010-12-20 2023-08-12 Not clear
M Morawski, G Brückner, C Jäger, G Seeger, T Arend. Neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in Alzheimer's disease. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20497908. neurons associated with aggrecan-based perineuronal nets are protected against tau pathology in subcortical regions in alzheimer's disease. 2010-12-16 2023-08-12 Not clear