All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Rudy J Castellani, Hyoung-Gon Lee, Xiongwei Zhu, George Perry, Mark A Smit. Alzheimer disease pathology as a host response. Journal of neuropathology and experimental neurology. vol 67. issue 6. 2008-07-15. PMID:18520771. identification of amyloid-beta and tau as the major protein components of senile plaques and neurofibrillary tangles, respectively, led to an exponential increase in investigations of these proteins and their corresponding metabolic pathways in alzheimer disease (ad). 2008-07-15 2023-08-12 Not clear
Marta Tajes, Javier Gutierrez-Cuesta, Jaume Folch, Isidre Ferrer, Beatriz Caballero, Mark A Smith, Gemma Casadesus, Antoni Camins, Mercé Pallá. Lithium treatment decreases activities of tau kinases in a murine model of senescence. Journal of neuropathology and experimental neurology. vol 67. issue 6. 2008-07-15. PMID:18520779. lithium modulates glycogen synthase kinase 3beta (gsk-3beta), a kinase involved in alzheimer disease-related tau pathology. 2008-07-15 2023-08-12 mouse
Delphine Boche, James A R Nicol. The role of the immune system in clearance of Abeta from the brain. Brain pathology (Zurich, Switzerland). vol 18. issue 2. 2008-07-10. PMID:18363937. in alzheimer's disease (ad), there is abnormal accumulation of abeta and tau proteins in the brain. 2008-07-10 2023-08-12 Not clear
Erin E Congdon, Sohee Kim, Jonathan Bonchak, Tanakorn Songrug, Anastasios Matzavinos, Jeff Kure. Nucleation-dependent tau filament formation: the importance of dimerization and an estimation of elementary rate constants. The Journal of biological chemistry. vol 283. issue 20. 2008-07-09. PMID:18359772. filamentous inclusions composed of the microtubule-associated protein tau are found in alzheimer disease and other tauopathic neurodegenerative diseases, but the mechanisms underlying their formation from full-length protein monomer under physiological conditions are unclear. 2008-07-09 2023-08-12 human
Jeffrey A Fein, Sophie Sokolow, Carol A Miller, Harry V Vinters, Fusheng Yang, Gregory M Cole, Karen Hoppens Gyly. Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18467692. co-localization of amyloid beta and tau pathology in alzheimer's disease synaptosomes. 2008-07-08 2023-08-12 Not clear
Jeffrey A Fein, Sophie Sokolow, Carol A Miller, Harry V Vinters, Fusheng Yang, Gregory M Cole, Karen Hoppens Gyly. Co-localization of amyloid beta and tau pathology in Alzheimer's disease synaptosomes. The American journal of pathology. vol 172. issue 6. 2008-07-08. PMID:18467692. we examined the regional distribution and co-localization of abeta and phosphorylated tau (p-tau) in synaptic terminals of alzheimer's disease brains. 2008-07-08 2023-08-12 Not clear
A Rametti, F Esclaire, C Yardin, N Cogné, F Terr. Lithium down-regulates tau in cultured cortical neurons: a possible mechanism of neuroprotection. Neuroscience letters. vol 434. issue 1. 2008-07-03. PMID:18289787. in tauopathies such as alzheimer's disease (ad), the moleccular mechanisms of tau protein agregation into neurofibrillary tangles (nfts) and their contribution to neurodegeneration are not fully understood. 2008-07-03 2023-08-12 Not clear
Andrew J Larne. Mutation negative "early-onset familial Alzheimer disease": consider screening for tau gene mutations. Alzheimer disease and associated disorders. vol 22. issue 2. 2008-07-03. PMID:18525295. mutation negative "early-onset familial alzheimer disease": consider screening for tau gene mutations. 2008-07-03 2023-08-12 Not clear
Andrew J Larne. Mutation negative "early-onset familial Alzheimer disease": consider screening for tau gene mutations. Alzheimer disease and associated disorders. vol 22. issue 2. 2008-07-03. PMID:18525295. as these genes prove to be negative in patients with a clinical diagnosis of early-onset familial alzheimer disease, a search for tau gene mutations may be appropriate, as illustrated by the following case. 2008-07-03 2023-08-12 Not clear
Paula I Moreira, Maria S Santos, Catarina R Oliveira, Justin C Shenk, Akihiko Nunomura, Mark A Smith, Xiongwei Zhu, George Perr. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS & neurological disorders drug targets. vol 7. issue 1. 2008-07-02. PMID:18289026. furthermore, it has been suggested that in the initial stages of the development of alzheimer disease, amyloid-beta deposition and hyperphosphorylated tau function as compensatory responses to ensure that neuronal cells do not succumb to oxidative damage. 2008-07-02 2023-08-12 Not clear
Daniela Galimberti, Eliana Venturelli, Chiara Fenoglio, Ilaria Guidi, Chiara Villa, Luigi Bergamaschini, Francesca Cortini, Diego Scalabrini, Pierluigi Baron, Carlo Vergani, Nereo Bresolin, Elio Scarpin. Intrathecal levels of IL-6, IL-11 and LIF in Alzheimer's disease and frontotemporal lobar degeneration. Journal of neurology. vol 255. issue 4. 2008-07-01. PMID:18204920. cerebrospinal fluid (csf) levels of interleukin (il)-6, il-11 and leukaemia inhibitory factor (lif) were evaluated in 43 patients with alzheimer's disease (ad) and 24 patients with frontotemporal lobar degeneration (ftld) as compared with 30 agematched controls (con), and correlated with clinical and demographic data and with csf biomarkers amyloid beta (a beta)42, total tau and tau phosphorylated at position 181 (p-tau). 2008-07-01 2023-08-12 Not clear
Y-J Zhang, Y-F Xu, X-H Liu, D Li, J Yin, Y-H Liu, X-Q Chen, J-Z Wan. Carboxyl terminus of heat-shock cognate 70-interacting protein degrades tau regardless its phosphorylation status without affecting the spatial memory of the rats. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 3. 2008-07-01. PMID:18301957. accumulation of the hyperphosphorylated tau is a hallmark pathological event for the formation of neurofibrillary tangles in alzheimer disease (ad). 2008-07-01 2023-08-12 rat
Jormay Lim, Martin Balastik, Tae Ho Lee, Kazuhiro Nakamura, Yih-Cherng Liou, Anyang Sun, Greg Finn, Lucia Pastorino, Virginia M-Y Lee, Kun Ping L. Pin1 has opposite effects on wild-type and P301L tau stability and tauopathy. The Journal of clinical investigation. vol 118. issue 5. 2008-07-01. PMID:18431510. tau pathology is a hallmark of many neurodegenerative diseases including alzheimer disease (ad) and frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17). 2008-07-01 2023-08-12 mouse
Sachio Matsushita, Tomohiro Miyakawa, Hitoshi Maesato, Toshifumi Matsui, Akira Yokoyama, Hiroyuki Arai, Susumu Higuchi, Haruo Kashim. Elevated cerebrospinal fluid tau protein levels in Wernicke's encephalopathy. Alcoholism, clinical and experimental research. vol 32. issue 6. 2008-07-01. PMID:18445112. we also examined csf total tau in nonalcohol dependent patients with alzheimer's disease (ad) as a disease control. 2008-07-01 2023-08-12 Not clear
Ovidiu C Andronesi, Martin von Bergen, Jacek Biernat, Karsten Seidel, Christian Griesinger, Eckhard Mandelkow, Marc Baldu. Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy. Journal of the American Chemical Society. vol 130. issue 18. 2008-06-23. PMID:18386894. the polymerization of the microtubule-associated protein tau into paired helical filaments (phfs) represents one of the hallmarks of alzheimer's disease. 2008-06-23 2023-08-12 Not clear
Ovidiu C Andronesi, Martin von Bergen, Jacek Biernat, Karsten Seidel, Christian Griesinger, Eckhard Mandelkow, Marc Baldu. Characterization of Alzheimer's-like paired helical filaments from the core domain of tau protein using solid-state NMR spectroscopy. Journal of the American Chemical Society. vol 130. issue 18. 2008-06-23. PMID:18386894. we employed solid-state nuclear magnetic resonance (nmr) to investigate the structure and dynamics of phfs formed in vitro by the three-repeat-domain (k19) of protein tau, representing the core of alzheimer phfs. 2008-06-23 2023-08-12 Not clear
Gustavo Basurto-Islas, Jose Luna-Muñoz, Angela L Guillozet-Bongaarts, Lester I Binder, Raul Mena, Francisco García-Sierr. Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease. Journal of neuropathology and experimental neurology. vol 67. issue 5. 2008-06-20. PMID:18431250. accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in alzheimer disease. 2008-06-20 2023-08-12 Not clear
Gustavo Basurto-Islas, Jose Luna-Muñoz, Angela L Guillozet-Bongaarts, Lester I Binder, Raul Mena, Francisco García-Sierr. Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease. Journal of neuropathology and experimental neurology. vol 67. issue 5. 2008-06-20. PMID:18431250. truncations of tau protein at aspartic acid421 (d421) and glutamic acid391 (e391) residues are associated with neurofibrillary tangles (nfts) in the brains of alzheimer disease (ad) patients. 2008-06-20 2023-08-12 Not clear
Ismael Santa-Mara, Gabriel Santpere, Michael J MacDonald, Elena Gomez de Barreda, Felix Hernandez, Francisco J Moreno, Isidro Ferrer, Jesús Avil. Coenzyme q induces tau aggregation, tau filaments, and Hirano bodies. Journal of neuropathology and experimental neurology. vol 67. issue 5. 2008-06-20. PMID:18431254. tau aggregation is a common feature of tauopathies such as alzheimer disease (ad). 2008-06-20 2023-08-12 Not clear
Ignacio Mateo, Pascual Sánchez-Juan, Eloy Rodríguez-Rodríguez, Jon Infante, Carlos Fernández-Viadero, Nicolás Peña, José Berciano, Onofre Combarro. 14-3-3 zeta and tau genes interactively decrease Alzheimer's disease risk. Dementia and geriatric cognitive disorders. vol 25. issue 4. 2008-06-17. PMID:18319590. 14-3-3 zeta and tau genes interactively decrease alzheimer's disease risk. 2008-06-17 2023-08-12 human