All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
R Skrabana, M Skrabanova, N Csokova, J Sevcik, M Nova. Intrinsically disordered tau protein in Alzheimer's tangles: a coincidence or a rule? Bratislavske lekarske listy. vol 107. issue 9-10. 2007-03-15. PMID:17262987. intrinsically disordered tau protein in alzheimer's tangles: a coincidence or a rule? 2007-03-15 2023-08-12 Not clear
R Skrabana, M Skrabanova, N Csokova, J Sevcik, M Nova. Intrinsically disordered tau protein in Alzheimer's tangles: a coincidence or a rule? Bratislavske lekarske listy. vol 107. issue 9-10. 2007-03-15. PMID:17262987. tau protein, the major constituent of neurofibrillary tangles in alzheimer's disease (ad) and related tauopathies, is classified as intrinsically disordered protein (idp). 2007-03-15 2023-08-12 Not clear
Yasumasa Yoshiyama, Makoto Higuchi, Bin Zhang, Shu-Ming Huang, Nobuhisa Iwata, Takaomi C Saido, Jun Maeda, Tetsuya Suhara, John Q Trojanowski, Virginia M-Y Le. Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model. Neuron. vol 53. issue 3. 2007-03-15. PMID:17270732. filamentous tau inclusions are hallmarks of alzheimer's disease (ad) and related tauopathies, but earlier pathologies may herald disease onset. 2007-03-15 2023-08-12 mouse
Hai-Long Hou, Yu-Xian Shen, Hong-Yan Zhu, Hao Sun, Xue-Bo Yan, Hui Fang, Jiang-Ning Zho. Alterations of hHrd1 expression are related to hyperphosphorylated tau in the hippocampus in Alzheimer's disease. Journal of neuroscience research. vol 84. issue 8. 2007-03-13. PMID:17044033. alterations of hhrd1 expression are related to hyperphosphorylated tau in the hippocampus in alzheimer's disease. 2007-03-13 2023-08-12 Not clear
Hai-Long Hou, Yu-Xian Shen, Hong-Yan Zhu, Hao Sun, Xue-Bo Yan, Hui Fang, Jiang-Ning Zho. Alterations of hHrd1 expression are related to hyperphosphorylated tau in the hippocampus in Alzheimer's disease. Journal of neuroscience research. vol 84. issue 8. 2007-03-13. PMID:17044033. the degradation of aberrantly phosphorylated tau in neurons plays an important role in the pathogenesis of alzheimer's disease (ad). 2007-03-13 2023-08-12 Not clear
Miroslava Hrnkova, Norbert Zilka, Zuzana Minichova, Peter Koson, Michal Nova. Neurodegeneration caused by expression of human truncated tau leads to progressive neurobehavioural impairment in transgenic rats. Brain research. vol 1130. issue 1. 2007-03-13. PMID:17169350. human truncated tau protein is an active constituent of the neurofibrillary degeneration in sporadic alzheimer's disease. 2007-03-13 2023-08-12 human
Luc Buée, André Delacourt. [Tauopathy and Alzheimer disease: a full degenerating process]. Psychologie & neuropsychiatrie du vieillissement. vol 4. issue 4. 2007-03-13. PMID:17194646. in the present work, the role of tau pathology as both diagnostic marker and therapeutic target is highlighted in alzheimer disease and related disorders. 2007-03-13 2023-08-12 Not clear
Martin Cente, Peter Filipcik, Miroslava Pevalova, Michal Nova. Expression of a truncated tau protein induces oxidative stress in a rodent model of tauopathy. The European journal of neuroscience. vol 24. issue 4. 2007-03-06. PMID:16930434. truncation of tau protein and oxidative stress have been implicated as important pathogenetic events in tauopathies including alzheimer's disease (ad). 2007-03-06 2023-08-12 human
Noriyuki Matsukawa, Kosei Ojik. [Function of HCNP/HCNP precursor in memory formation]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 26. issue 5-6. 2007-03-06. PMID:17240848. hcnp and its precursor can be a candidate for the key molecules elucidating the underlying association among abeta, phosphorylated tau, degeneration of dendritic spine and decrease of acetylcholine in alzheimer brain. 2007-03-06 2023-08-12 rat
Y Zhang, H-L Li, D-L Wang, S-J Liu, J-Z Wan. A transitory activation of protein kinase-A induces a sustained tau hyperphosphorylation at multiple sites in N2a cells-imply a new mechanism in Alzheimer pathology. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 10. 2007-03-02. PMID:16465464. a transitory activation of protein kinase-a induces a sustained tau hyperphosphorylation at multiple sites in n2a cells-imply a new mechanism in alzheimer pathology. 2007-03-02 2023-08-12 Not clear
Y Zhang, H-L Li, D-L Wang, S-J Liu, J-Z Wan. A transitory activation of protein kinase-A induces a sustained tau hyperphosphorylation at multiple sites in N2a cells-imply a new mechanism in Alzheimer pathology. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 10. 2007-03-02. PMID:16465464. it is suggested that only transitory activation of pka in early stage of alzheimer disease may result in a sustained tau hyperphosphorylation at multiple sites, implying a new mechanism to alzheimer-like tau hyperphosphorylation. 2007-03-02 2023-08-12 Not clear
Chun Lai Nie, Xing Sheng Wang, Ying Liu, Sarah Perrett, Rong Qiao H. Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells. BMC neuroscience. vol 8. 2007-02-28. PMID:17241479. the microtubule associated protein tau is the principle component of neurofibrillar tangles, which are a characteristic marker in the pathology of alzheimer's disease; similar lesions are also observed after chronic alcohol abuse. 2007-02-28 2023-08-12 Not clear
Rostislav Skrabana, Michaela Skrabanova-Khuebachova, Peter Kontsek, Michal Nova. Alzheimer's-disease-associated conformation of intrinsically disordered tau protein studied by intrinsically disordered protein liquid-phase competitive enzyme-linked immunosorbent assay. Analytical biochemistry. vol 359. issue 2. 2007-02-27. PMID:17081491. tau protein, the major constituent of paired helical filaments in alzheimer's disease, belongs to the intrinsically disordered proteins (idps). 2007-02-27 2023-08-12 Not clear
Evan Elliott, Irith Ginzbur. The role of neurotrophins and insulin on tau pathology in Alzheimer's disease. Reviews in the neurosciences. vol 17. issue 6. 2007-02-27. PMID:17283608. the role of neurotrophins and insulin on tau pathology in alzheimer's disease. 2007-02-27 2023-08-12 Not clear
Evan Elliott, Irith Ginzbur. The role of neurotrophins and insulin on tau pathology in Alzheimer's disease. Reviews in the neurosciences. vol 17. issue 6. 2007-02-27. PMID:17283608. alterations in the structure and function of tau protein is the primary pathology of a variety of neurodegenerative diseases, including alzheimer's disease (ad). 2007-02-27 2023-08-12 Not clear
Hugo Vanderstichele, Karen De Vreese, Kaj Blennow, Niels Andreasen, Christian Sindic, Adrian Ivanoiu, Harald Hampel, Katharina Bürger, Lucilla Parnetti, Alessia Lanari, Allesandro Padovani, Monica DiLuca, Miriam Bläser, Annika Ohrfelt Olsson, Hans Pottel, Frank Hulstaert, Eugeen Vanmechele. Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies. Clinical chemistry and laboratory medicine. vol 44. issue 12. 2007-02-26. PMID:17163825. total tau (t-tau) and beta-amyloid((1-42)) (abeta(1-42)) levels in cerebrospinal fluid (csf) can differentiate alzheimer's disease (ad) from normal aging or depressive pseudo-dementia. 2007-02-26 2023-08-12 Not clear
K Leroy, Z Yilmaz, J-P Brio. Increased level of active GSK-3beta in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration. Neuropathology and applied neurobiology. vol 33. issue 1. 2007-02-26. PMID:17239007. the somatodendritic accumulation of hyperphosphorylated tau proteins is an early event preceding the appearance of neurofibrillary tangles (nft) in alzheimer's disease (ad) and might be necessary for their formation. 2007-02-26 2023-08-12 Not clear
Odity Mukherjee, John S K Kauwe, Kevin Mayo, John C Morris, Alison M Goat. Haplotype-based association analysis of the MAPT locus in late onset Alzheimer's disease. BMC genetics. vol 8. 2007-02-26. PMID:17266761. a prominent hypothesis for the aetiopathology of alzheimer's disease is that in the presence of a beta-amyloid load, individuals expressing a pathogenic form of tau protein (mapt) are at increased risk for developing the disease. 2007-02-26 2023-08-12 Not clear
Ian W Jones, Adam Westmacott, Elcie Chan, Roy W Jones, Kelly Dineley, Michael J O'Neill, Susan Wonnacot. Alpha7 nicotinic acetylcholine receptor expression in Alzheimer's disease: receptor densities in brain regions of the APP(SWE) mouse model and in human peripheral blood lymphocytes. Journal of molecular neuroscience : MN. vol 30. issue 1-2. 2007-02-23. PMID:17192639. the brains of people with alzheimer's disease (ad) display several characteristic pathological features, including deposits (plaques) of beta-amyloid 1-42 (abeta1-42), intraneuronal accumulations (tangles) of hyperphosphorylated tau, degeneration of the basal forebrain cholinergic pathway, and gliosis. 2007-02-23 2023-08-12 mouse
E N Kapaki, G P Paraskevas, N G Tzerakis, C Sfagos, A Seretis, E Kararizou, D Vassilopoulo. Cerebrospinal fluid tau, phospho-tau181 and beta-amyloid1-42 in idiopathic normal pressure hydrocephalus: a discrimination from Alzheimer's disease. European journal of neurology. vol 14. issue 2. 2007-02-23. PMID:17250725. cerebrospinal fluid tau, phospho-tau181 and beta-amyloid1-42 in idiopathic normal pressure hydrocephalus: a discrimination from alzheimer's disease. 2007-02-23 2023-08-12 Not clear