| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sophia Weiner, Mathias Sauer, Gunnar Brinkmalm, Julius Constantinescu, Radu Constantinescu, Bárbara Fernandes Gomes, Bruno Becker, Bengt Nellgård, Keti Dalla, Douglas Galasko, Henrik Zetterberg, Kaj Blennow, Johan Gobo. SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-03-22. PMID:36946611. |
scrn1: a cerebrospinal fluid biomarker correlating with tau in alzheimer's disease. |
2023-03-22 |
2023-08-14 |
Not clear |
| Sophia Weiner, Mathias Sauer, Gunnar Brinkmalm, Julius Constantinescu, Radu Constantinescu, Bárbara Fernandes Gomes, Bruno Becker, Bengt Nellgård, Keti Dalla, Douglas Galasko, Henrik Zetterberg, Kaj Blennow, Johan Gobo. SCRN1: A cerebrospinal fluid biomarker correlating with tau in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-03-22. PMID:36946611. |
secernin-1 (scrn1) is a neuronal protein that co-localizes with neurofibrillary tangles in alzheimer's disease (ad), but not with tau inclusions in corticobasal degeneration (cbd), progressive supranuclear palsy (psp), or pick's disease. |
2023-03-22 |
2023-08-14 |
Not clear |
| Sadiruldeen Sami Abed, Farqad Bader Hamdan, Mahir Mohammed Hussein, Qasim Sharhan Al-Maya. Plasma tau and neurofilament light chain as biomarkers of Alzheimer's disease and their relation to cognitive functions. Journal of medicine and life. vol 16. issue 2. 2023-03-20. PMID:36937471. |
plasma tau and neurofilament light chain as biomarkers of alzheimer's disease and their relation to cognitive functions. |
2023-03-20 |
2023-08-14 |
human |
| Hillary Protas, Valentina Ghisays, Dhruman D Goradia, Robert Bauer, Vivek Devadas, Kewei Chen, Eric M Reiman, Yi S. Individualized network analysis: A novel approach to investigate tau PET using graph theory in the Alzheimer's disease continuum. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937677. |
individualized network analysis: a novel approach to investigate tau pet using graph theory in the alzheimer's disease continuum. |
2023-03-20 |
2023-08-14 |
Not clear |
| Hillary Protas, Valentina Ghisays, Dhruman D Goradia, Robert Bauer, Vivek Devadas, Kewei Chen, Eric M Reiman, Yi S. Individualized network analysis: A novel approach to investigate tau PET using graph theory in the Alzheimer's disease continuum. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937677. |
tau pet imaging has emerged as an important tool to detect and monitor tangle burden in vivo in the study of alzheimer's disease (ad). |
2023-03-20 |
2023-08-14 |
Not clear |
| Ran Li, Beibei Song, Lu Xu, Jiali Zheng, Wenhao Pan, Fang Cai, Juelu Wang, Yili Wu, Weihong Son. Regulation of USP25 by SP1 Associates with Amyloidogenesis. Journal of Alzheimer's disease : JAD. 2023-03-20. PMID:36938736. |
individuals with ds inevitably develop alzheimer's disease (ad) neuropathological phenotypes after middle age including amyloid plaques and tau neurofibrillary tangles. |
2023-03-20 |
2023-08-14 |
human |
| A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic Tau mouse model of Alzheimer disease. Human molecular genetics. 2023-03-20. PMID:36939074. |
a partial reduction of drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic tau mouse model of alzheimer disease. |
2023-03-20 |
2023-08-14 |
mouse |
| Yu-Qing Liu, Chu-Qiao Liang, Zhi-Wei Chen, Jun Hu, Jin-Jian Hu, Yun-Yi Luo, Yong-Xiang Chen, Yan-Mei L. 14-3-3ζ Participates in the Phase Separation of Phosphorylated and Glycated Tau and Modulates the Physiological and Pathological Functions of Tau. ACS chemical neuroscience. 2023-03-20. PMID:36939323. |
tau plays a major role in alzheimer's disease (ad) and several other neurodegenerative diseases. |
2023-03-20 |
2023-08-14 |
Not clear |
| Shubhrat Maheshwar. AGEs RAGE Pathways: Alzheimer's Disease. Drug research. 2023-03-20. PMID:36940723. |
neurofibrillary tangles and plaques containing tau serve as the biological markers for alzheimer disease (ad) and pathogenesis is widely believed to be driven by the production and deposition of the β-amyloid peptide (aβ). |
2023-03-20 |
2023-08-14 |
Not clear |
| Kaitlin M Stouffer, Claire Chen, Sue Kulason, Eileen Xu, Menno P Witter, Can Ceritoglu, Marilyn S Albert, Susumu Mori, Juan Troncoso, Daniel J Tward, Michael I Mille. Early amygdala and ERC atrophy linked to 3D reconstruction of rostral neurofibrillary tau tangle pathology in Alzheimer's disease. NeuroImage. Clinical. vol 38. 2023-03-19. PMID:36934675. |
early amygdala and erc atrophy linked to 3d reconstruction of rostral neurofibrillary tau tangle pathology in alzheimer's disease. |
2023-03-19 |
2023-08-14 |
Not clear |
| Kaitlin M Stouffer, Claire Chen, Sue Kulason, Eileen Xu, Menno P Witter, Can Ceritoglu, Marilyn S Albert, Susumu Mori, Juan Troncoso, Daniel J Tward, Michael I Mille. Early amygdala and ERC atrophy linked to 3D reconstruction of rostral neurofibrillary tau tangle pathology in Alzheimer's disease. NeuroImage. Clinical. vol 38. 2023-03-19. PMID:36934675. |
previous research has emphasized the unique impact of alzheimer's disease (ad) pathology on the medial temporal lobe (mtl), a reflection that tau pathology is particularly striking in the entorhinal and transentorhinal cortex (erc, tec) early in the course of disease. |
2023-03-19 |
2023-08-14 |
Not clear |
| Gilda E Ennis, Tobey J Betthauser, Rebecca Langhough Koscik, Nathaniel A Chin, Bradley T Christian, Sanjay Asthana, Sterling C Johnson, Barbara B Bendli. The relationship of insulin resistance and diabetes to tau PET SUVR in middle-aged to older adults. Alzheimer's research & therapy. vol 15. issue 1. 2023-03-18. PMID:36932429. |
insulin resistance (ir) and type 2 diabetes have been found to increase the risk for alzheimer's clinical syndrome in epidemiologic studies but have not been associated with tau tangles in neuropathological research and have been inconsistently associated with cerebrospinal fluid p-tau181. |
2023-03-18 |
2023-08-14 |
Not clear |
| Alexis M Johnson, John R Luken. The innate immune response in tauopathies. European journal of immunology. 2023-03-18. PMID:36932726. |
tauopathies, which include frontotemporal dementia, alzheimer's disease, and chronic traumatic encephalopathy, are a class of neurological disorders resulting from pathogenic tau aggregates. |
2023-03-18 |
2023-08-14 |
Not clear |
| Philip S J Weston, William Coath, Matthew J Harris, Ian B Malone, John Dickson, Franklin I Aigbirhio, David M Cash, Hui Zhang, Jonathan M Schot. Cortical tau is associated with microstructural imaging biomarkers of neurite density and dendritic complexity in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-03-18. PMID:36932979. |
cortical tau is associated with microstructural imaging biomarkers of neurite density and dendritic complexity in alzheimer's disease. |
2023-03-18 |
2023-08-14 |
Not clear |
| Philip S J Weston, William Coath, Matthew J Harris, Ian B Malone, John Dickson, Franklin I Aigbirhio, David M Cash, Hui Zhang, Jonathan M Schot. Cortical tau is associated with microstructural imaging biomarkers of neurite density and dendritic complexity in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-03-18. PMID:36932979. |
in alzheimer's disease (ad), hyperphosphorylated tau is closely associated with focal neurodegeneration, but the mechanism remains uncertain. |
2023-03-18 |
2023-08-14 |
Not clear |
| Sian-Hong Ciou, Ao-Ho Hsieh, Yu-Xiu Lin, Jhao-Liang Sei, Mani Govindasamy, Chang-Fu Kuo, Chi-Hsien Huan. Sensitive label-free detection of the biomarker phosphorylated tau-217 protein in Alzheimer's disease using a graphene-based solution-gated field effect transistor. Biosensors & bioelectronics. vol 228. 2023-03-18. PMID:36933321. |
alzheimer's disease (ad) is generally diagnosed using advanced imaging, but recent research suggests early screening using biomarkers in peripheral blood is feasible; among them, plasma tau proteins phosphorylated at threonine 231, threonine 181, and threonine 217 (p-tau217) are potential targets. |
2023-03-18 |
2023-08-14 |
human |
| Hyunjun Yang, Peng Yuan, Yibing Wu, Marie Shi, Christoffer D Caro, Atsushi Tengeiji, Shigeo Yamanoi, Masahiro Inoue, William F DeGrado, Carlo Condell. EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 12. 2023-03-17. PMID:36927157. |
our ember (excitation multiplexed bright emission recording) imaging method rapidly identifies conformational differences in aβ and tau deposits from down syndrome, sporadic and familial alzheimer's disease human brain slices. |
2023-03-17 |
2023-08-14 |
mouse |
| Priyadarshi Prajjwal, Shahnaz Asharaf, Dhruvi Makhanasa, Aishwarya Yamparala, Halla Tariq, Soumya Aleti, Srikanth Gadam, Neel Vor. Association of Alzheimer's dementia with oral bacteria, vitamin B12, folate, homocysteine levels, and insulin resistance along with its pathophysiology, genetics, imaging, and biomarkers. Disease-a-month : DM. 2023-03-17. PMID:36931946. |
despite numerous studies, the exact cause of alzheimer's disease remains uncertain, and various theories have been proposed, including aβ amyloid deposition in the brain and tau protein hyper-phosphorylation. |
2023-03-17 |
2023-08-14 |
Not clear |
| Priyadarshi Prajjwal, Shahnaz Asharaf, Dhruvi Makhanasa, Aishwarya Yamparala, Halla Tariq, Soumya Aleti, Srikanth Gadam, Neel Vor. Association of Alzheimer's dementia with oral bacteria, vitamin B12, folate, homocysteine levels, and insulin resistance along with its pathophysiology, genetics, imaging, and biomarkers. Disease-a-month : DM. 2023-03-17. PMID:36931946. |
neuroimaging techniques, including mri, pet, and tau pet, can identify the predictive characteristics of alzheimer's disease, with amyloid pet being the most useful in ruling out the disease. |
2023-03-17 |
2023-08-14 |
Not clear |
| Ryusei Kaneko, Ako Matsui, Mahiro Watanabe, Yoshihiro Harada, Mitsuhiro Kanamori, Natsumi Awata, Mio Kawazoe, Tomoaki Takao, Yutaro Kobayashi, Chie Kikutake, Mikita Suyama, Takashi Saito, Takaomi C Saido, Minako It. Increased neutrophils in inflammatory bowel disease accelerate the accumulation of amyloid plaques in the mouse model of Alzheimer's disease. Inflammation and regeneration. vol 43. issue 1. 2023-03-16. PMID:36922861. |
alzheimer's disease (ad) is one of the neurodegenerative diseases and characterized by the appearance and accumulation of amyloid-β (aβ) aggregates and phosphorylated tau with aging. |
2023-03-16 |
2023-08-14 |
mouse |