All Relations between Alzheimer Disease and microtubule-associated protein tau

Publication Sentence Publish Date Extraction Date Species
Mohd Adnan, Saleha Anwar, Debarati DasGupta, Mitesh Patel, Abdelbaset Mohamed Elasbali, Hassan H Alhassan, Alaa Shafie, Arif Jamal Siddiqui, Fevzi Bardakci, Mejdi Snoussi, Md Imtaiyaz Hassa. Targeting inhibition of microtubule affinity regulating kinase 4 by Harmaline: Strategy to combat Alzheimer's disease. International journal of biological macromolecules. 2022-10-18. PMID:36257368. due to its direct role in the hyper-phosphorylation of tau protein, mark4 is considered as an attractive target to fight alzheimer's disease and neuroinflammation. 2022-10-18 2023-08-14 Not clear
Ramón Martínez-Mármol, Christopher Small, Anmin Jiang, Tishila Palliyaguru, Tristan P Wallis, Rachel S Gormal, Jean-Baptiste Sibarita, Jürgen Götz, Frédéric A Meunie. Fyn nanoclustering requires switching to an open conformation and is enhanced by FTLD-Tau biomolecular condensates. Molecular psychiatry. 2022-10-18. PMID:36258016. postsynaptic enrichment of fyn underpins synaptotoxicity in dementias such as alzheimer's disease and frontotemporal lobar degeneration with tau pathology (ftld-tau). 2022-10-18 2023-08-14 Not clear
Josef Marksteiner, Michaela Defrancesco, Christian Humpe. Saliva tau and phospho-tau-181 measured by Lumipulse in patients with Alzheimer's disease. Frontiers in aging neuroscience. vol 14. 2022-10-17. PMID:36247998. saliva tau and phospho-tau-181 measured by lumipulse in patients with alzheimer's disease. 2022-10-17 2023-08-14 human
Pijush Chakraborty, Markus Zweckstette. Phase separation of the microtubule-associated protein tau. Essays in biochemistry. 2022-10-17. PMID:36251053. the aggregation and misfolding of the neuronal microtubule-associated protein tau is closely linked to the pathology of alzheimer's disease and several other neurodegenerative diseases. 2022-10-17 2023-08-14 Not clear
Qiang Qiang, Loren Skudder-Hill, Tomoko Toyota, Wenshi Wei, Hiroaki Adach. CSF GAP-43 as a biomarker of synaptic dysfunction is associated with tau pathology in Alzheimer's disease. Scientific reports. vol 12. issue 1. 2022-10-17. PMID:36253408. csf gap-43 as a biomarker of synaptic dysfunction is associated with tau pathology in alzheimer's disease. 2022-10-17 2023-08-14 human
b' Dietmar Rudolf Thal, Sandra O Tom\\xc3\\xa. The central role of tau in Alzheimer\'s disease: From neurofibrillary tangle maturation to the induction of cell death. Brain research bulletin. 2022-10-16. PMID:36244581.' the central role of tau in alzheimer's disease: from neurofibrillary tangle maturation to the induction of cell death. 2022-10-16 2023-08-14 Not clear
b' Dietmar Rudolf Thal, Sandra O Tom\\xc3\\xa. The central role of tau in Alzheimer\'s disease: From neurofibrillary tangle maturation to the induction of cell death. Brain research bulletin. 2022-10-16. PMID:36244581.' the tau protein (τ) is one of the two hallmark proteins of alzheimer's disease (ad) together with the amyloid β protein (aβ). 2022-10-16 2023-08-14 Not clear
Sujin Kim, Yunkwon Nam, Soo Jung Shin, Ritu Prajapati, Seong Min Shin, Min-Jeong Kim, Hyeon Soo Kim, Seol Hwa Leem, Tae-Jin Kim, Yong Ho Park, Jwa-Jin Kim, Jae Sue Choi, Minho Moo. Dual modulators of aggregation and dissociation of amyloid beta and tau: In vitro, in vivo, and in silico studies of Uncaria rhynchophylla and its bioactive components. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-10-15. PMID:36242849. a prominent characteristic of alzheimer's disease (ad) is the deposition of both amyloid-β (aβ) peptide and tau protein in the brain. 2022-10-15 2023-08-14 Not clear
Lenka Hromadkova, Mohammad Khursheed Siddiqi, He Liu, Jiri G Safa. Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer's Disease and Related Dementias. Cells. vol 11. issue 19. 2022-10-14. PMID:36230957. populations of tau conformers drive prion-like strain effects in alzheimer's disease and related dementias. 2022-10-14 2023-08-14 human
Lenka Hromadkova, Mohammad Khursheed Siddiqi, He Liu, Jiri G Safa. Populations of Tau Conformers Drive Prion-like Strain Effects in Alzheimer's Disease and Related Dementias. Cells. vol 11. issue 19. 2022-10-14. PMID:36230957. recent findings of diverse populations of prion-like conformers of misfolded tau protein expand the prion concept to alzheimer's disease (ad) and monogenic frontotemporal lobar degeneration (ftld)-mapt p301l, and suggest that distinct strains of misfolded proteins drive the phenotypes and progression rates in many neurodegenerative diseases. 2022-10-14 2023-08-14 human
Julia Sala-Jarque, Karolina Zimkowska, Jesús Ávila, Isidro Ferrer, José Antonio Del Rí. Towards a Mechanistic Model of Tau-Mediated Pathology in Tauopathies: What Can We Learn from Cell-Based In Vitro Assays? International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232835. in alzheimer's disease, and other related tauopathies, the pattern of tau deposition follows a stereotypical progression between anatomically connected brain regions. 2022-10-14 2023-08-14 Not clear
Yuta Katsumi, Deepti Putcha, Ryan Eckbo, Bonnie Wong, Megan Quimby, Scott McGinnis, Alexandra Touroutoglou, Bradford C Dickerso. Anterior dorsal attention network tau drives visual attention deficits in posterior cortical atrophy. Brain : a journal of neurology. 2022-10-14. PMID:36237170. posterior cortical atrophy (pca), usually an atypical clinical syndrome of alzheimer's disease, has well-characterized patterns of cortical atrophy and tau deposition that are distinct from typical amnestic presentations of alzheimer's disease. 2022-10-14 2023-08-14 Not clear
Kyung Hoon Lee, Koung Mi Kan. [Association between Cerebral Small Vessel and Alzheimer's Disease]. Taehan Yongsang Uihakhoe chi. vol 83. issue 3. 2022-10-14. PMID:36238505. there is accumulating evidence that vascular changes may play an important role in development of alzheimer's disease (ad), and csvd lesions detected on brain mri were reported to be associated with β-amyloid and tau proteins accumulation. 2022-10-14 2023-08-14 Not clear
Yu Kyeong Ki. [Recent Updates on PET Imaging in Neurodegenerative Diseases]. Taehan Yongsang Uihakhoe chi. vol 83. issue 3. 2022-10-14. PMID:36238518. amyloid-β and tau deposition in pet images are now key diagnostic biomarkers for the alzheimer's disease continuum. 2022-10-14 2023-08-14 Not clear
Won-Jin Moo. [Alzheimer Dementia and Microvascular Pathology: Blood-Brain Barrier Permeability Imaging]. Taehan Yongsang Uihakhoe chi. vol 81. issue 3. 2022-10-14. PMID:36238621. accumulating evidence suggests that alzheimer's disease (ad) is not only caused by accumulation of abnormal proteins, including amyloid and tau, but is also closely associated with abnormalities in the microvascular environment including the blood-brain barrier (bbb), both of which lead to neuroinflammation and neurodegeneration. 2022-10-14 2023-08-14 Not clear
Bindu D Pau. DUB'ling down uncovers an X-linked vulnerability in Alzheimer's disease. Cell. vol 185. issue 21. 2022-10-14. PMID:36240738. show that aberrantly high activity of x-linked usp11 deubiquitinase in women impairs clearance of tau, the principal component of neurofibrillary tangles in alzheimer's disease. 2022-10-14 2023-08-14 Not clear
Emma M Coomans, Inge M W Verberk, Rik Ossenkoppele, Sander C J Verfaillie, Denise Visser, Mariam Gouda, Hayel Tuncel, Emma E Wolters, Tessa Timmers, Albert D Windhorst, Sandeep S V Golla, Philip Scheltens, Wiesje M van der Flier, Bart N M van Berckel, Charlotte E Teunisse. A head-to-head comparison between plasma pTau181 and tau-PET along the Alzheimer's disease continuum. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2022-10-13. PMID:36229187. both plasma tau phosphorylated at threonine-181 (ptau181) and tau positron emission tomography (tau-pet) show potential for detecting alzheimer's disease (ad) pathology and predicting clinical progression. 2022-10-13 2023-08-14 Not clear
Armine Hovakimyan, Karen Zagorski, Gor Chailyan, Tatevik Antonyan, Levon Melikyan, Irina Petrushina, Dash G Batt, Olga King, Manush Ghazaryan, Aashrit Donthi, Caitlynn Foose, Nikolai Petrovsky, David H Cribbs, Michael G Agadjanyan, Anahit Ghochikya. Immunogenicity of MultiTEP platform technology-based Tau vaccine in non-human primates. NPJ vaccines. vol 7. issue 1. 2022-10-12. PMID:36224191. pathological forms of tau protein are directly associated with neurodegeneration and correlate with alzheimer's disease (ad) symptoms, progression, and severity. 2022-10-12 2023-08-14 mouse
Chen-Ye Mou, Yan-Fei Xie, Jia-Xin Wei, Qi-Yao Wang, Jing-Yang Le, Yong-Jie Bao, Pan-Pan Zhang, Yue-Chun Mao, Xing-Han Huang, Han-Bo Pan, C Benjamin Naman, Lin Liu, Hong-Ze Liang, Xiang Wu, Jia Xu, Wei Cu. Rose Bengal inhibits β-amyloid oligomers-induced tau hyperphosphorylation via acting on Akt and CDK5 kinases. Psychopharmacology. 2022-10-11. PMID:36221038. tau hyperphosphorylation and aggregation is considered as a main pathological mechanism underlying alzheimer's disease (ad). 2022-10-11 2023-08-14 drosophila_melanogaster
Tao-Ran Li, Di-Yang Lyu, Feng-Qi Li. Cerebrospinal Fluid sTREM2 in Alzheimer's Disease Is Associated with Both Amyloid and Tau Pathologies but not with Cognitive Status. Journal of Alzheimer's disease : JAD. 2022-10-10. PMID:36213998. cerebrospinal fluid strem2 in alzheimer's disease is associated with both amyloid and tau pathologies but not with cognitive status. 2022-10-10 2023-08-14 Not clear