| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Cheng, Jie-Ming Jian, Chen-Yang He, Jun-Rong Ren, Man-Yu Xu, Wang-Sheng Jin, Cheng-Rong Tan, Gui-Hua Zeng, Ying-Ying Shen, Dong-Wan Chen, Hui-Yun Li, Xu Yi, Yuan Zhang, Fan Zeng, Yan-Jiang Wan. The Correlations of Plasma Liver-Type Fatty Acid-Binding Protein with Amyloid-β and Tau Levels in Patients with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-05-23. PMID:35599489. |
the correlations of plasma liver-type fatty acid-binding protein with amyloid-β and tau levels in patients with alzheimer's disease. |
2022-05-23 |
2023-08-13 |
Not clear |
| Yi-Liang Tsai, Chieh-Tsung Yen, Yuh-Feng Wan. Astrocyte Dysregulation and Calcium Ion Imbalance May Link the Development of Osteoporosis and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-05-23. PMID:35599492. |
the typical symptoms of patients with alzheimer's disease (ad) are amyloid-β (aβ) plaques and tau hyperphosphorylation. |
2022-05-23 |
2023-08-13 |
Not clear |
| Fátima Mesa-Herrera, Raquel Marín, Eduardo Torrealba, Guido Santos, Mario Día. Neuronal ER-Signalosome Proteins as Early Biomarkers in Prodromal Alzheimer's Disease Independent of Amyloid-β Production and Tau Phosphorylation. Frontiers in molecular neuroscience. vol 15. 2022-05-23. PMID:35600079. |
neuronal er-signalosome proteins as early biomarkers in prodromal alzheimer's disease independent of amyloid-β production and tau phosphorylation. |
2022-05-23 |
2023-08-13 |
Not clear |
| Min-Seok Kim, Yeon-Seon Mun, Seung-Eun Lee, Woo-Young Cho, Seung-Hwan Han, Dong-Hou Kim, Seung-Yong Yoo. Tau acetylation at K280 regulates tau phosphorylation. The International journal of neuroscience. 2022-05-23. PMID:35603448. |
accumulation of hyperphosphorylated tau is a key pathological finding of alzheimer's disease. |
2022-05-23 |
2023-08-13 |
Not clear |
| Davide Bruno, Ainara Jauregi Zinkunegi, Nunzio Pomara, Henrik Zetterberg, Kaj Blennow, Rebecca Langhough Koscik, Cynthia Carlsson, Barbara Bendlin, Ozioma Okonkwo, Bruce P Hermann, Sterling C Johnson, Kimberly D Muelle. Cross-sectional associations of CSF tau levels with Rey's AVLT: A recency ratio study. Neuropsychology. 2022-05-23. PMID:35604714. |
the preeminent in vivo cerebrospinal fluid (csf) biomarkers of alzheimer's disease (ad) are amyloid β 1-42 (aβ42), phosphorylated tau (p-tau), and total tau (t-tau). |
2022-05-23 |
2023-08-13 |
Not clear |
| Isabelle Aillaud, Susanne Aileen Funk. Tau Aggregation Inhibiting Peptides as Potential Therapeutics for Alzheimer Disease. Cellular and molecular neurobiology. 2022-05-21. PMID:35596819. |
tau aggregation inhibiting peptides as potential therapeutics for alzheimer disease. |
2022-05-21 |
2023-08-13 |
Not clear |
| Hailun Jiang, Jianghong Liu, Shuilong Guo, Li Zeng, Zhongdi Cai, Junxia Zhang, Linlin Wang, Zhuorong Li, Rui Li. miR-23b-3p rescues cognition in Alzheimer's disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways. Molecular therapy. Nucleic acids. vol 28. 2022-05-20. PMID:35592504. |
mir-23b-3p rescues cognition in alzheimer's disease by reducing tau phosphorylation and apoptosis via gsk-3β signaling pathways. |
2022-05-20 |
2023-08-13 |
mouse |
| Hailun Jiang, Jianghong Liu, Shuilong Guo, Li Zeng, Zhongdi Cai, Junxia Zhang, Linlin Wang, Zhuorong Li, Rui Li. miR-23b-3p rescues cognition in Alzheimer's disease by reducing tau phosphorylation and apoptosis via GSK-3β signaling pathways. Molecular therapy. Nucleic acids. vol 28. 2022-05-20. PMID:35592504. |
dysregulated microrna (mirna) expression in the brain can contribute to cognitive dysfunction and aberrant tau hyperphosphorylation in alzheimer's disease (ad). |
2022-05-20 |
2023-08-13 |
mouse |
| Samar O El-Ganainy, Omar A Soliman, Aya A Ghazy, Maram Allam, Aya I Elbahnasi, Amira M Mansour, Mennatallah A Gowaye. Intranasal Oxytocin Attenuates Cognitive Impairment, β-Amyloid Burden and Tau Deposition in Female Rats with Alzheimer's Disease: Interplay of ERK1/2/GSK3β/Caspase-3. Neurochemical research. 2022-05-20. PMID:35596040. |
intranasal oxytocin attenuates cognitive impairment, β-amyloid burden and tau deposition in female rats with alzheimer's disease: interplay of erk1/2/gsk3β/caspase-3. |
2022-05-20 |
2023-08-13 |
rat |
| Xiaoli Li, Jinhe Han, Sheshurao Bujaranipalli, Jie He, Eun Young Kim, Hee Kim, Jae Hong Im, Won-Jea Ch. Structure-based discovery and development of novel O-GlcNAcase inhibitors for the treatment of Alzheimer's disease. European journal of medicinal chemistry. vol 238. 2022-05-19. PMID:35588599. |
the neurofibrillary tangles (nfts) formed from hyperphosphorylation of tau protein are closely associated with alzheimer's disease (ad). |
2022-05-19 |
2023-08-13 |
mouse |
| Fakhteh Aliakbari, Farnoosh Attar, Monireh Movahedi, Mojtaba Falahat. Human tau fibrillization and neurotoxicity in the presence of magnesium oxide nanoparticle fabricated through laser ablation method. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. vol 278. 2022-05-19. PMID:35588606. |
in this study, the acceleratory effect of magnesium oxide nanoparticles (mgo nps) on the amyloid fibrillization of human tau protein, a major protein involved in the onset of alzheimer's disease (ad) was investigated. |
2022-05-19 |
2023-08-13 |
human |
| John C Morris, Michael Weiner, Chengjie Xiong, Laurel Beckett, Dean Coble, Naomi Saito, Paul S Aisen, Ricardo Allegri, Tammie L S Benzinger, Sarah B Berman, Nigel J Cairns, Maria C Carrillo, Helena C Chui, Jasmeer P Chhatwal, Carlos Cruchaga, Anne M Fagan, Martin Farlow, Nick C Fox, Bernardino Ghetti, Alison M Goate, Brian A Gordon, Neill Graff-Radford, Gregory S Day, Jason Hassenstab, Takeshi Ikeuchi, Clifford R Jack, William J Jagust, Mathias Jucker, Johannes Levin, Parinaz Massoumzadeh, Colin L Masters, Ralph Martins, Eric McDade, Hiroshi Mori, James M Noble, Ronald C Petersen, John M Ringman, Stephen Salloway, Andrew J Saykin, Peter R Schofield, Leslie M Shaw, Arthur W Toga, John Q Trojanowski, Jonathan Vöglein, Stacie Weninger, Randall J Bateman, Virginia D Buckle. Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. Brain : a journal of neurology. 2022-05-17. PMID:35580594. |
we compared brain magnetic resonance imaging and amyloid positron emission tomography data, as well as cerebrospinal fluid concentrations of amyloid-beta-42, amyloid-beta-40, tau, and tau phosphorylated at position 181, in 292 carriers of pathogenic variants for alzheimer disease from the dominantly inherited alzheimer network with corresponding data from 559 participants from the alzheimer's disease neuroimaging initiative. |
2022-05-17 |
2023-08-13 |
human |
| John C Morris, Michael Weiner, Chengjie Xiong, Laurel Beckett, Dean Coble, Naomi Saito, Paul S Aisen, Ricardo Allegri, Tammie L S Benzinger, Sarah B Berman, Nigel J Cairns, Maria C Carrillo, Helena C Chui, Jasmeer P Chhatwal, Carlos Cruchaga, Anne M Fagan, Martin Farlow, Nick C Fox, Bernardino Ghetti, Alison M Goate, Brian A Gordon, Neill Graff-Radford, Gregory S Day, Jason Hassenstab, Takeshi Ikeuchi, Clifford R Jack, William J Jagust, Mathias Jucker, Johannes Levin, Parinaz Massoumzadeh, Colin L Masters, Ralph Martins, Eric McDade, Hiroshi Mori, James M Noble, Ronald C Petersen, John M Ringman, Stephen Salloway, Andrew J Saykin, Peter R Schofield, Leslie M Shaw, Arthur W Toga, John Q Trojanowski, Jonathan Vöglein, Stacie Weninger, Randall J Bateman, Virginia D Buckle. Autosomal dominant and sporadic late onset Alzheimer disease share a common in vivo pathophysiology. Brain : a journal of neurology. 2022-05-17. PMID:35580594. |
although amyloid burden accumulation as determined by positron emission tomography was greater after symptomatic onset in autosomal dominant alzheimer disease than in late onset alzheimer disease participants, cerebrospinal fluid assays of amyloid-beta-42, amyloid-beta-40, tau, and p-tau181 were largely overlapping in both groups. |
2022-05-17 |
2023-08-13 |
human |
| Lone Helboe, Nina Rosenqvist, Christiane Volbracht, Lars Ø Pedersen, Jan T Pedersen, Søren Christensen, Jan Egebjerg, Claus T Christoffersen, Benny Bang-Andersen, Thomas G Beach, Geidy E Serrano, Jeppe Falsi. Highly Specific and Sensitive Target Binding by the Humanized pS396-Tau Antibody hC10.2 Across a Wide Spectrum of Alzheimer's Disease and Primary Tauopathy Postmortem Brains. Journal of Alzheimer's disease : JAD. 2022-05-16. PMID:35570492. |
deposits of hyperphosphorylated tau fibrils are hallmarks of a broad spectrum of tauopathies, including alzheimer's disease (ad). |
2022-05-16 |
2023-08-13 |
Not clear |
| James S Clark, Rakez Kayed, Giulia Abate, Daniela Uberti, Paul Kinnon, Simona Piccirell. Post-translational Modifications of the p53 Protein and the Impact in Alzheimer's Disease: A Review of the Literature. Frontiers in aging neuroscience. vol 14. 2022-05-16. PMID:35572126. |
our understanding of alzheimer's disease (ad) pathogenesis has developed with several hypotheses over the last 40 years, including the amyloid and tau hypotheses. |
2022-05-16 |
2023-08-13 |
Not clear |
| Diyang Lyu, Jianping Ji. Cryptotanshinone Attenuates Amyloid-β Molecular neurobiology. 2022-05-16. PMID:35575872. |
cryptotanshinone attenuates amyloid-β the pathological characteristics of alzheimer's disease (ad) include formation of senile plaques resulting from amyloid-β (aβ) deposition and neurofibrillary tangles caused by tau hyperphosphorylation. |
2022-05-16 |
2023-08-13 |
Not clear |
| Isidro Ferrer, Pol Andrés-Benito, Paula Garcia-Esparcia, Irene López-Gonzalez, Diego Valiente, Mónica Jordán-Pirla, Margarita Carmona, Julia Sala-Jarque, Vanessa Gil, José Antonio Del Ri. Differences in Tau Seeding in Newborn and Adult Wild-Type Mice. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563179. |
alzheimer's disease (ad) and other tauopathies are common neurodegenerative diseases in older adults; in contrast, abnormal tau deposition in neurons and glial cells occurs only exceptionally in children. |
2022-05-14 |
2023-08-13 |
mouse |
| Veronika Brezovakova, Eva Sykova, Santosh Jadha. Astrocytes Derived from Familial and Sporadic Alzheimer's Disease iPSCs Show Altered Calcium Signaling and Respond Differently to Misfolded Protein Tau. Cells. vol 11. issue 9. 2022-05-14. PMID:35563735. |
astrocytes derived from familial and sporadic alzheimer's disease ipscs show altered calcium signaling and respond differently to misfolded protein tau. |
2022-05-14 |
2023-08-13 |
mouse |
| Yang You, Samuel W Hersh, Roshanak Aslebagh, Scott A Shaffer, Seiko Ikezu, Jesse Mez, Kathryn L Lunetta, Mark W Logue, Lindsay A Farrer, Tsuneya Ikez. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Aging cell. 2022-05-14. PMID:35567427. |
alzheimer's disease associated akap9 i2558m mutation alters posttranslational modification and interactome of tau and cellular functions in crispr-edited human neuronal cells. |
2022-05-14 |
2023-08-13 |
human |
| Hironori Takamura, Yoshiaki Nakayama, Hidefumi Ito, Taiichi Katayama, Paul E Fraser, Shinsuke Matsuzak. SUMO1 Modification of Tau in Progressive Supranuclear Palsy. Molecular neurobiology. 2022-05-14. PMID:35567706. |
sumo1 conjugation has been shown to promote aggregation and regulate phosphorylation of the tau protein linked to alzheimer's disease and related tauopathies. |
2022-05-14 |
2023-08-13 |
Not clear |