All Relations between Alzheimer Disease and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

Reference Sentence Publish Date Extraction Date Species
Mohammad Qneibi, Mohammad Hawash, Nidal Jaradat, Sosana Bdi. Affecting AMPA Receptor Biophysical Gating Properties with Negative Allosteric Modulators. Molecular neurobiology vol issue 2022 35687302 ampa receptor-mediated synaptic transmission abnormalities may play a role in neurologic and neurodegenerative diseases, and compounds that can modulate ampa receptor (ampar) signaling have been studied for decades as possible therapies for alzheimer's disease, parkinson's disease, depression, and epilepsy. 2022-06-10 2022-06-13 Not clear
Qi Shen, Lei Liu, Xiaotong Gu, Da Xin. Photobiomodulation suppresses JNK3 by activation of ERK/MKP7 to attenuate AMPA receptor endocytosis in Alzheimer's disease. Aging cell vol 20 issue 1 2021 33336891 photobiomodulation suppresses jnk3 by activation of erk/mkp7 to attenuate ampa receptor endocytosis in alzheimer's disease. 2021-09-02 2022-01-13 Not clear
Parvin Babae. NMDA and AMPA receptors dysregulation in Alzheimer's disease. European journal of pharmacology vol 908 issue 2021 34265291 nmda and ampa receptors dysregulation in alzheimer's disease. 2021-08-20 2022-01-13 Not clear
Lon S Schneider, Ronald G Thomas, Suzanne Hendrix, Robert A Rissman, James B Brewer, David P Salmon, Tilman Oltersdorf, Tomohiro Okuda, Howard H Feldma. Safety and Efficacy of Edonerpic Maleate for Patients With Mild to Moderate Alzheimer Disease: A Phase 2 Randomized Clinical Trial. JAMA neurology vol 76 issue 11 2021 31282954 these effects may be mediated via sigma-1 receptor activation, delivery of synaptic ampa receptors, or modulation of microglial function and may benefit patients with alzheimer disease. 2021-05-03 2022-01-13 Not clear
Wenrui Qu, Baoming Yuan, Jun Liu, Qianqian Liu, Xi Zhang, Ranji Cui, Wei Yang, Bingjin L. Emerging role of AMPA receptor subunit GluA1 in synaptic plasticity: Implications for Alzheimer's disease. Cell proliferation vol 54 issue 1 2021 33188547 emerging role of ampa receptor subunit glua1 in synaptic plasticity: implications for alzheimer's disease. 2021-01-19 2022-01-13 Not clear
Margaret O'Connor, Yang-Ping Shentu, Guan Wang, Wen-Ting Hu, Zhen-Dong Xu, Xiao-Chuan Wang, Rong Liu, Heng-Ye Ma. Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease. iScience vol 23 issue 9 2021 32861999 acetylation of ampa receptors regulates receptor trafficking and rescues memory deficits in alzheimer's disease. 2021-01-10 2022-01-13 Not clear
Margaret O'Connor, Yang-Ping Shentu, Guan Wang, Wen-Ting Hu, Zhen-Dong Xu, Xiao-Chuan Wang, Rong Liu, Heng-Ye Ma. Acetylation of AMPA Receptors Regulates Receptor Trafficking and Rescues Memory Deficits in Alzheimer's Disease. iScience vol 23 issue 9 2021 32861999 in alzheimer's disease (ad), decreases in the amount and synaptic localization of ampa receptors (ampars) result in weakened synaptic activity and dysfunction in synaptic plasticity, leading to impairments in cognitive functions. 2021-01-10 2022-01-13 Not clear
Alejandro Mart\\xc3\\xadn-Belmonte, Carolina Aguado, Roc\\xc3\\xado Alfaro-Ru\\xc3\\xadz, Makoto Itakura, Ana Esther Moreno-Mart\\xc3\\xadnez, Luis de la Ossa, Elek Moln\\xc3\\xa1r, Yugo Fukazawa, Rafael Luj\\xc3\\xa1. Age-Dependent Shift of AMPA Receptors From Synapses to Intracellular Compartments in Alzheimer's Disease: Immunocytochemical Analysis of the CA1 Hippocampal Region in APP/PS1 Transgenic Mouse Model. Frontiers in aging neuroscience vol 12 issue 2020 33132900 age-dependent shift of ampa receptors from synapses to intracellular compartments in alzheimer's disease: immunocytochemical analysis of the ca1 hippocampal region in app/ps1 transgenic mouse model. 2020-11-03 2022-01-13 Not clear
Katy Bernard, Sylvie Gouttefangeas, Sylvie Bretin, St\\xc3\\xa9phanie Galtier, Philippe Robert, Vjera Holthoff-Detto, Jeffrey Cummings, Maria Puey. A 24-week double-blind placebo-controlled study of the efficacy and safety of the AMPA modulator S47445 in patients with mild to moderate Alzheimer's disease and depressive symptoms. Alzheimer's & dementia (New York, N. Y.) vol 5 issue 2020 31297437 a 24-week double-blind placebo-controlled study of the efficacy and safety of the ampa modulator s47445 in patients with mild to moderate alzheimer's disease and depressive symptoms. 2020-10-01 2022-01-13 Not clear
Nazanin Mozafari, Ali Shamsizadeh, Iman Fatemi, Mohammad Allahtavakoli, Amir Moghadam-Ahmadi, Elham Kaviani, Ayat Kaeid. CX691, as an AMPA receptor positive modulator, improves the learning and memory in a rat model of Alzheimer's disease. Iranian journal of basic medical sciences vol 21 issue 7 2020 30140412 cx691, as an ampa receptor positive modulator, improves the learning and memory in a rat model of alzheimer's disease. 2020-09-30 2022-01-13 Not clear
Nazanin Mozafari, Ali Shamsizadeh, Iman Fatemi, Mohammad Allahtavakoli, Amir Moghadam-Ahmadi, Elham Kaviani, Ayat Kaeid. CX691, as an AMPA receptor positive modulator, improves the learning and memory in a rat model of Alzheimer's disease. Iranian journal of basic medical sciences vol 21 issue 7 2020 30140412 growing evidence suggests that dysfunction of the glutamatergic system and \xce\xb1-amino-3-hydroxy-5-methyl-4-isoazolepropionic acid (ampa) receptors are involved in pathology of alzheimer's disease (ad). 2020-09-30 2022-01-13 Not clear
Lan-Xue Zhao, Yan-Hui Ge, Jia-Bing Li, Cai-Hong Xiong, Ping-Yee Law, Jian-Rong Xu, Yu Qiu, Hong-Zhuan Che. M1 muscarinic receptors regulate the phosphorylation of AMPA receptor subunit GluA1 FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 33 issue 5 2020 30794430 m1 muscarinic receptors regulate the phosphorylation of ampa receptor subunit glua1 m1 muscarinic acetylcholine receptors are highly expressed in key areas that control cognition, such as the cortex and hippocampus, representing one potential therapeutic target for cognitive dysfunctions of alzheimer's disease and schizophrenia. 2020-05-12 2022-01-13 Not clear
David Baglietto-Vargas, Gilberto Aleph Prieto, Agenor Limon, Stefania Forner, Carlos J Rodriguez-Ortiz, Kenji Ikemura, Rahasson R Ager, Rodrigo Medeiros, Laura Trujillo-Estrada, Alessandra C Martini, Masashi Kitazawa, Jose C Davila, Carl W Cotman, Antonia Gutierrez, Frank M LaFerl. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging cell vol 17 issue 4 2019 29877034 impaired ampa signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of alzheimer's disease. 2019-10-07 2022-01-13 Not clear
Yanmin Zhang, Ouyang Guo, Yuda Huo, Guan Wang, Heng-Ye Ma. Amyloid-\\xce\\xb2 Induces AMPA Receptor Ubiquitination and Degradation in Primary Neurons and Human Brains of Alzheimer's Disease. Journal of Alzheimer's disease : JAD vol 62 issue 4 2019 29614651 amyloid-\xce\xb2 induces ampa receptor ubiquitination and degradation in primary neurons and human brains of alzheimer's disease. 2019-05-28 2022-01-13 Not clear
S Bretin, A Krazem, N Henkous, C Froger-Colleaux, E Mocaer, C Louis, N Perdaems, A Marighetto, D Beracoche. Synergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice. Psychopharmacology vol 235 issue 3 2019 29167913 since donepezil, an acetylcholinesterase inhibitor, induces only moderate symptomatic effects on memory in alzheimer's disease patients, an alternative strategy for treatment of cognitive symptoms could be to act simultaneously on both glutamatergic ampa receptors and cholinergic pathways by combining pharmacological treatments. 2019-01-25 2022-01-13 Not clear
Douglas J Marcotte, Jean-Christophe Hus, Charles C Banos, Craig Wildes, Robert Arduini, Chris Bergeron, Catherine A Hession, Darren P Baker, Edward Lin, Kevin M Guckian, Anthone W Dunah, Laura F Silvia. Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. Protein science : a publication of the Protein Society vol 27 issue 3 2019 29280296 reduction of surface ampa type receptors on neurons reduces synaptic communication leading to cognitive impairment in progressive neurodegenerative diseases such as alzheimer disease. 2019-01-11 2022-01-13 Not clear
M\\xc3\\xa9lanie H Thomas, C\\xc3\\xa9dric Paris, Myl\\xc3\\xa8ne Magnien, Julie Colin, Sandra Pelle\\xc3\\xafeux, Florence Coste, Marie-Christine Escany\\xc3\\xa9, Thierry Pillot, Jean-Luc Olivie. Dietary arachidonic acid increases deleterious effects of amyloid-\\xce\\xb2 oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA Alzheimer's research & therapy vol 9 issue 1 2018 28851448 dietary arachidonic acid increases deleterious effects of amyloid-\xce\xb2 oligomers on learning abilities and expression of ampa receptors: putative role of the acsl4-cpla polyunsaturated fatty acids play a crucial role in neuronal function, and the modification of these compounds in the brain could have an impact on neurodegenerative diseases such as alzheimer's disease. 2018-04-27 2022-01-13 Not clear
Nadia Regina Rodrigues, Ana Paula Ferreira de Souz. Occurrence of glyphosate and AMPA residues in soy-based infant formula sold in Brazil. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment vol 35 issue 4 2018 29267136 recently, glyphosate and its metabolite aminomethylphosphonic acid (ampa) have been identified as possible contributors to the emergence of various diseases such as autism, parkinson's and alzheimer's diseases, as well as cancer. 2018-04-16 2022-01-13 Not clear
Jean-Pascal Morin, Sof\\xc3\\xada D\\xc3\\xadaz-Cintra, Federico Berm\\xc3\\xbadez-Rattoni, Ilse Delint-Ram\\xc3\\xadre. Decreased levels of NMDA but not AMPA receptors in the lipid-raft fraction of 3xTg-AD model of Alzheimer's disease: Relation to Arc/Arg3.1 protein expression. Neurochemistry international vol 100 issue 2018 27650435 decreased levels of nmda but not ampa receptors in the lipid-raft fraction of 3xtg-ad model of alzheimer's disease: relation to arc/arg3.1 protein expression. 2018-01-31 2022-01-12 Not clear
Jean-Pascal Morin, Sof\\xc3\\xada D\\xc3\\xadaz-Cintra, Federico Berm\\xc3\\xbadez-Rattoni, Ilse Delint-Ram\\xc3\\xadre. Decreased levels of NMDA but not AMPA receptors in the lipid-raft fraction of 3xTg-AD model of Alzheimer's disease: Relation to Arc/Arg3.1 protein expression. Neurochemistry international vol 100 issue 2018 27650435 as a first effort to address this issue, we evaluated lipid-raft contents of distinct nmda and ampa receptor subunits in the hippocampus of the 3xtg-ad model of alzheimer's disease. 2018-01-31 2022-01-12 Not clear
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