All Relations between Alzheimer Disease and microglial cell

Publication Sentence Publish Date Extraction Date Species
Hansen Wan. Microglia Heterogeneity in Alzheimer's Disease: Insights From Single-Cell Technologies. Frontiers in synaptic neuroscience. vol 13. 2022-01-10. PMID:35002670. microglia heterogeneity in alzheimer's disease: insights from single-cell technologies. 2022-01-10 2023-08-13 mouse
Hansen Wan. Microglia Heterogeneity in Alzheimer's Disease: Insights From Single-Cell Technologies. Frontiers in synaptic neuroscience. vol 13. 2022-01-10. PMID:35002670. the pathology of alzheimer's disease (ad) triggers activation of microglia. 2022-01-10 2023-08-13 mouse
Juan R Perea, Marta Bolós, Raquel Cuadros, Esther García, Vega García-Escudero, Félix Hernández, Róisín M McManus, Michael T Heneka, Jesús Avil. p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function. Molecular neurobiology. 2022-01-10. PMID:35006531. alzheimer's disease (ad) and other tauopathies are histopathologically characterized by tau aggregation, along with a chronic inflammatory response driven by microglia. 2022-01-10 2023-08-13 Not clear
Tal Ganz, Nina Fainstein, Amit Elad, Marva Lachish, Smadar Goldfarb, Ofira Einstein, Tamir Ben-Hu. Microbial pathogens induce neurodegeneration in Alzheimer's disease mice: protection by microglial regulation. Journal of neuroinflammation. vol 19. issue 1. 2022-01-07. PMID:34991645. we hypothesized that systemic microbial pathogens may accelerate neurodegeneration in alzheimer's disease (ad) and that microglia play a central role in this process. 2022-01-07 2023-08-13 mouse
Faheem Ullah, Rashmi Gamage, Monokesh K Sen, Erika Gyenges. The Effects of Modified Curcumin Preparations on Glial Morphology in Aging and Neuroinflammation. Neurochemical research. 2022-01-06. PMID:34988899. neuroinflammation is characterized by reactive microglia and astrocytes (collectively called gliosis) in the central nervous system and is considered as one of the main pathological hallmarks in different neurodegenerative diseases such as alzheimer's disease, age-related dementia, and multiple sclerosis. 2022-01-06 2023-08-13 Not clear
Pengzhen Wang, Peng Yang, Kang Qian, Yixian Li, Shuting Xu, Ran Meng, Qian Guo, Yunlong Cheng, Jinxu Cao, Minjun Xu, Wei Lu, Qizhi Zhan. Precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by TREM2 for treatment of Alzheimer's disease. Biomaterials. vol 281. 2022-01-06. PMID:34991033. precise gene delivery systems with detachable albumin shell remodeling dysfunctional microglia by trem2 for treatment of alzheimer's disease. 2022-01-06 2023-08-13 mouse
Katherine E Prater, Kevin J Green, Kenneth L Chiou, Carole L Smith, Wei Sun, Ali Shojaie, Laura M Heath, Shannon Rose, C Dirk Keene, Benjamin A Logsdon, Noah Snyder-Mackler, Elizabeth E Blue, Jessica E Young, Gwenn A Garden, Suman Jayade. Microglia subtype transcriptomes differ between Alzheimer Disease and control human postmortem brain samples. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971137. microglia subtype transcriptomes differ between alzheimer disease and control human postmortem brain samples. 2021-12-31 2023-08-13 human
LuLin Jiang, Xiaoguang Li, Stephanie Myers, Timothy Huang, Randal J Kaufma. Astroglial ER protein Membralin is an essential neuroinflammation regulator. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 2. 2021-12-31. PMID:34971195. glial cells, including astrocytes and microglia, are the immune cells in the brains, becoming reactive/gliosis during the progression of alzheimer's disease (ad). 2021-12-31 2023-08-13 mouse
Paul M Kim, Michael D Kornber. Targeting PKC in microglia to promote remyelination and repair in the CNS. Current opinion in pharmacology. vol 62. 2021-12-29. PMID:34965482. microglia and cns-infiltrating macrophages play significant roles in the pathogenesis of neuroinflammatory and neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, and multiple sclerosis. 2021-12-29 2023-08-13 Not clear
Arthur A Vandenbark, Halina Offner, Szymon Matejuk, Agata Mateju. Microglia and astrocyte involvement in neurodegeneration and brain cancer. Journal of neuroinflammation. vol 18. issue 1. 2021-12-24. PMID:34949203. here, we discuss recent perspectives on the role of microglia and astrocytes in neurological disorders, including the two most common neurodegenerative conditions, alzheimer disease and progranulin-related frontotemporal lobar dementia, as well as astrocytoma brain tumors. 2021-12-24 2023-08-13 Not clear
Seungmin Lee, In Gyoung Ju, Yujin Choi, Sangsu Park, Myung Sook O. Trichosanthis Semen Suppresses Lipopolysaccharide-Induced Neuroinflammation by Regulating the NF-κB Signaling Pathway and HO-1 Expression in Microglia. Toxins. vol 13. issue 12. 2021-12-23. PMID:34941735. neuroinflammation, which is mediated by microglia that release various inflammatory cytokines, is a typical feature of neurodegenerative diseases (ndds), such as alzheimer's disease and parkinson's disease. 2021-12-23 2023-08-13 Not clear
Irene Frigerio, Baayla D C Boon, Chen-Pei Lin, Yvon Galis-de Graaf, John Bol, Paolo Preziosa, Jos Twisk, Frederik Barkhof, Jeroen J M Hoozemans, Femke H Bouwman, Annemieke J M Rozemuller, Wilma D J van de Berg, Laura E Jonkma. Amyloid-β, p-tau and reactive microglia are pathological correlates of MRI cortical atrophy in Alzheimer's disease. Brain communications. vol 3. issue 4. 2021-12-20. PMID:34927073. amyloid-β, p-tau and reactive microglia are pathological correlates of mri cortical atrophy in alzheimer's disease. 2021-12-20 2023-08-13 Not clear
Étienne Gervais, Parisa Iloun, Ekaterina Martianova, Ana Claudia Gonçalves Bessa, Serge Rivest, Lisa Topolni. Structural analysis of the microglia-interneuron interactions in the CA1 hippocampal area of the APP/PS1 mouse model of Alzheimer's disease. The Journal of comparative neurology. 2021-12-17. PMID:34919273. here, we compared the interactions between microglia and parvalbumin (pv+) and somatostatin (som+) expressing interneurons in the ca1 hippocampal area of app/ps1 transgenic mice that mimic certain aspects of the alzheimer's disease (ad). 2021-12-17 2023-08-13 mouse
Denisa Palova, Natalia Turic Csokova, Karina Markova, Eva Kontsekova, Branislav Kovacech, Monika Zilkov. The engagement of microglia in tau-targeted immunotherapy in Alzheimer's disease. General physiology and biophysics. vol 40. issue 6. 2021-12-13. PMID:34897021. the engagement of microglia in tau-targeted immunotherapy in alzheimer's disease. 2021-12-13 2023-08-13 Not clear
Guimei Zhang, Zicheng Wang, Huiling Hu, Meng Zhao, Li Su. Microglia in Alzheimer's Disease: A Target for Therapeutic Intervention. Frontiers in cellular neuroscience. vol 15. 2021-12-13. PMID:34899188. microglia in alzheimer's disease: a target for therapeutic intervention. 2021-12-13 2023-08-13 Not clear
Yiliang Wang, Weisheng Luo, Xiaohui Wang, Yuying Ma, Lianzhou Huang, Yifei Wan. MAMDC2, a gene highly expressed in microglia of AD mice, positively regulated the innate antiviral response upon neurotropic virus infection. The Journal of infection. 2021-12-13. PMID:34902449. microglia, as central nervous system (cns)-resident macrophages, are the first line of defense against neurotropic virus infection, the immune response of which is implicated in numerous cns diseases, including alzheimer's disease (ad). 2021-12-13 2023-08-13 mouse
Caden M Henningfield, Miguel A Arreola, Neelakshi Soni, Elizabeth E Spangenberg, Kim N Gree. Microglia-specific ApoE knock-out does not alter Alzheimer's disease plaque pathogenesis or gene expression. Glia. vol 70. issue 2. 2021-12-10. PMID:34643971. previous studies suggest that microglial-expressed apolipoprotein e (apoe) is necessary to shift microglia into a neurodegenerative transcriptional state in alzheimer's disease (ad) mouse models. 2021-12-10 2023-08-13 mouse
Amy M Smith, Karen Davey, Stergios Tsartsalis, Combiz Khozoie, Nurun Fancy, See Swee Tang, Eirini Liaptsi, Maria Weinert, Aisling McGarry, Robert C J Muirhead, Steve Gentleman, David R Owen, Paul M Matthew. Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology. Acta neuropathologica. 2021-12-08. PMID:34767070. to better define roles that astrocytes and microglia play in alzheimer's disease (ad), we used single-nuclei rna-sequencing to comprehensively characterise transcriptomes in astrocyte and microglia nuclei selectively enriched during isolation post-mortem from neuropathologically defined ad and control brains with a range of amyloid-beta and phospho-tau (ptau) pathology. 2021-12-08 2023-08-13 human
Rishika Dhapola, Subhendu Shekhar Hota, Phulen Sarma, Anusuya Bhattacharyya, Bikash Medhi, Dibbanti HariKrishna Redd. Recent advances in molecular pathways and therapeutic implications targeting neuroinflammation for Alzheimer's disease. Inflammopharmacology. vol 29. issue 6. 2021-12-08. PMID:34813026. targeting these pathways and eventually ameliorating the activation of microglia can mitigate neuroinflammation and come out as a better therapeutic option for the treatment of alzheimer's disease. 2021-12-08 2023-08-13 Not clear
Tyler K Ulland, Andrea C Ewald, Andrew O Knutson, Kaitlyn M Marino, Stephanie M C Smith, Jyoti J Watter. Alzheimer's Disease, Sleep Disordered Breathing, and Microglia: Puzzling out a Common Link. Cells. vol 10. issue 11. 2021-12-08. PMID:34831129. alzheimer's disease, sleep disordered breathing, and microglia: puzzling out a common link. 2021-12-08 2023-08-13 mouse