| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Verena Haage, John F Tuddenham, Natacha Comandante-Lou, Alex Bautista, Anna Monzel, Rebecca Chiu, Masashi Fujita, Frankie G Garcia, Prabesh Bhattarai, Ronak Patel, Alice Buonfiglioli, Juan Idiarte, Mathieu Herman, Alison Rinderspacher, Angeliki Mela, Wenting Zhao, Michael G Argenziano, Julia L Furnari, Matei A Banu, Donald W Landry, Jeffrey N Bruce, Peter Canoll, Ya Zhang, Tal Nuriel, Caghan Kizil, Andrew A Sproul, Lotje D de Witte, Peter A Sims, Vilas Menon, Martin Picard, Philip L De Jage. A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer's disease. bioRxiv : the preprint server for biology. 2024-02-19. PMID:38370689. |
a pharmacological toolkit for human microglia identifies topoisomerase i inhibitors as immunomodulators for alzheimer's disease. |
2024-02-19 |
2024-02-21 |
human |
| Megan E Bosch, Hemraj B Dodiya, Julia Michalkiewicz, Choonghee Lee, Shabana M Shaik, Ian Q Weigle, Can Zhang, Jack Osborn, Aishwarya Nambiar, Priyam Patel, Samira Parhizkar, Xiaoqiong Zhang, Marie L Laury, Prasenjit Mondal, Ashley Gomm, Matthew John Schipma, Dania Mallah, Oleg Butovsky, Eugene B Chang, Rudolph E Tanzi, Jack A Gilbert, David M Holtzman, Sangram S Sisodi. Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Molecular neurodegeneration. vol 19. issue 1. 2024-02-16. PMID:38365827. |
bulk rnaseq analysis unveiled sex-specific changes in cerebral cortex transcriptome profiles, but most importantly, the transcriptome changes in the gv-971-treated male group revealed the involvement of microglia and inflammatory responses.conclusions in conclusion, these studies demonstrate the connection between the gut microbiome, neuroinflammation, and alzheimer's disease pathology while highlighting the potential therapeutic effect of gv-971. |
2024-02-16 |
2024-02-19 |
mouse |
| Carla Cuní-López, Romal Stewart, Lotta E Oikari, Tam Hong Nguyen, Tara L Roberts, Yifan Sun, Christine C Guo, Michelle K Lupton, Anthony R White, Hazel Que. Advanced patient-specific microglia cell models for pre-clinical studies in Alzheimer's disease. Journal of neuroinflammation. vol 21. issue 1. 2024-02-16. PMID:38365833. |
advanced patient-specific microglia cell models for pre-clinical studies in alzheimer's disease. |
2024-02-16 |
2024-02-19 |
Not clear |
| Panos Roussos, Roman Kosoy, John Fullard, Jaroslav Bendl, Steven Kleopoulos, Zhiping Shao, Stathis Argyriou, Deepika Mathur, James Vicari, Yixuan Ma, Jack Humphrey, Erica Brophy, Towfique Raj, Pavel Katsel, Georgios Voloudakis, Donghoon Lee, David Bennett, Vahram Haroutunian, Gabriel Hoffma. Alzheimer's disease transcriptional landscape in ex-vivo human microglia. Research square. 2024-02-12. PMID:38343831. |
alzheimer's disease transcriptional landscape in ex-vivo human microglia. |
2024-02-12 |
2024-02-15 |
human |
| Panos Roussos, Roman Kosoy, John Fullard, Jaroslav Bendl, Steven Kleopoulos, Zhiping Shao, Stathis Argyriou, Deepika Mathur, James Vicari, Yixuan Ma, Jack Humphrey, Erica Brophy, Towfique Raj, Pavel Katsel, Georgios Voloudakis, Donghoon Lee, David Bennett, Vahram Haroutunian, Gabriel Hoffma. Alzheimer's disease transcriptional landscape in ex-vivo human microglia. Research square. 2024-02-12. PMID:38343831. |
microglia are resident immune cells of the brain and are implicated in the etiology of alzheimer's disease (ad) and other diseases. |
2024-02-12 |
2024-02-15 |
human |
| Tao Yin, Metin Yesiltepe, Luciano D'Adami. Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias. EMBO reports. 2024-02-12. PMID:38347225. |
functional bri2-trem2 interactions in microglia: implications for alzheimer's and related dementias. |
2024-02-12 |
2024-02-15 |
mouse |
| Rocio Vicario, Stamatina Fragkogianni, Leslie Weber, Tomi Lazarov, Yang Hu, Samantha Y Hayashi, Barbara P Craddock, Nicholas D Socci, Araitz Alberdi, Ann Baako, Oyku Ay, Masato Ogishi, Estibaliz Lopez-Rodrigo, Rajya Kappagantula, Agnes Viale, Christine A Iacobuzio-Donahue, Ting Zhou, Richard M Ransohoff, Richard Chesworth, Omar Abdel-Wahab, Bertrand Boisson, Olivier Elemento, Jean-Laurent Casanova, W Todd Miller, Frederic Geissman. A microglia clonal inflammatory disorder in Alzheimer's Disease. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328106. |
a microglia clonal inflammatory disorder in alzheimer's disease. |
2024-02-08 |
2024-02-10 |
human |
| Fengdi Zhao, Xin Ma, Bing Yao, Li Che. scaDA: A Novel Statistical Method for Differential Analysis of Single-Cell Chromatin Accessibility Sequencing Data. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328112. |
in addition to demonstrating the highest power in three real sc-multiome data analyses, scada successfully identifies differentially accessible regions in microglia from sc-multiome data for an alzheimer 's disease (ad) study, regions which are most enriched in go terms related to neurogenesis, the clinical phenotype of ad, and snps identified in ad-associated gwas. |
2024-02-08 |
2024-02-10 |
Not clear |
| Yun Guo, Cheng-Kun Sun, Lian Tang, Meng-Shan Ta. Microglia PTK2B/Pyk2 in the Pathogenesis of Alzheimer's Disease. Current Alzheimer research. 2024-02-07. PMID:38321895. |
microglia ptk2b/pyk2 in the pathogenesis of alzheimer's disease. |
2024-02-07 |
2024-02-09 |
Not clear |
| Zezhong Lv, Lixi Chen, Ping Chen, Huipai Peng, Yi Rong, Wei Hong, Qiang Zhou, Nan Li, Boxing Li, Rosa C Paolicelli, Yang Zha. Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective. Neuron. 2024-02-01. PMID:38295790. |
in neurodegenerative diseases, including alzheimer's disease (ad), microglia undergo morphological and functional alterations. |
2024-02-01 |
2024-02-04 |
Not clear |
| Samantha M Rossano, Aubrey S Johnson, Anna Smith, Galen Ziaggi, Andrew Roetman, Diana Guzman, Amarachukwu Okafor, Julia Klein, Zeljko Tomljanovic, Yaakov Stern, Adam M Brickman, Seonjoo Lee, William C Kreisl, Patrick La. Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-02-01. PMID:38298155. |
microglia measured by tspo pet are associated with alzheimer's disease pathology and mediate key steps in a disease progression model. |
2024-02-01 |
2024-02-03 |
Not clear |
| Leelavathi N Madhu, Maheedhar Kodali, Raghavendra Upadhya, Shama Rao, Bing Shuai, Yogish Somayaji, Sahithi Attaluri, Maha Kirmani, Shreyan Gupta, Nathaniel Maness, Xiaolan Rao, James Cai, Ashok K Shett. Intranasally Administered EVs from hiPSC-derived NSCs Alter the Transcriptomic Profile of Activated Microglia and Conserve Brain Function in an Alzheimer's Model. bioRxiv : the preprint server for biology. 2024-01-31. PMID:38293018. |
intranasally administered evs from hipsc-derived nscs alter the transcriptomic profile of activated microglia and conserve brain function in an alzheimer's model. |
2024-01-31 |
2024-02-02 |
mouse |
| Ziqi Fan, Xinyi Zhang, Shuai Zhao, Siyan Zhong, Zheyu Li, Yaping Yan, Baorong Zhang, Yanxing Che. Interferon Regulatory Factor 5 Regulates the Phagocytosis of Microglia and Alleviate Alzheimer's Pathology. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024-01-25. PMID:38271298. |
interferon regulatory factor 5 regulates the phagocytosis of microglia and alleviate alzheimer's pathology. |
2024-01-25 |
2024-01-28 |
mouse |
| Ziqi Fan, Xinyi Zhang, Shuai Zhao, Siyan Zhong, Zheyu Li, Yaping Yan, Baorong Zhang, Yanxing Che. Interferon Regulatory Factor 5 Regulates the Phagocytosis of Microglia and Alleviate Alzheimer's Pathology. The journals of gerontology. Series A, Biological sciences and medical sciences. 2024-01-25. PMID:38271298. |
microglia play a critical role in the pathophysiology of alzheimer's disease (ad). |
2024-01-25 |
2024-01-28 |
mouse |
| Lijie Zhang, Qiuru Yao, Jinjing Hu, Baizhi Qiu, Yupeng Xiao, Qi Zhang, Yuting Zeng, Shuqi Zheng, Youao Zhang, Yantong Wan, Xiaoyan Zheng, Qing Zen. Hotspots and trends of microglia in Alzheimer's disease: a bibliometric analysis during 2000-2022. European journal of medical research. vol 29. issue 1. 2024-01-24. PMID:38268044. |
hotspots and trends of microglia in alzheimer's disease: a bibliometric analysis during 2000-2022. |
2024-01-24 |
2024-01-27 |
Not clear |
| Lijie Zhang, Qiuru Yao, Jinjing Hu, Baizhi Qiu, Yupeng Xiao, Qi Zhang, Yuting Zeng, Shuqi Zheng, Youao Zhang, Yantong Wan, Xiaoyan Zheng, Qing Zen. Hotspots and trends of microglia in Alzheimer's disease: a bibliometric analysis during 2000-2022. European journal of medical research. vol 29. issue 1. 2024-01-24. PMID:38268044. |
currently, ample evidence has shown that microglia are closely related to the occurrence and development of alzheimer's disease. |
2024-01-24 |
2024-01-27 |
Not clear |
| August Yue Huang, Zinan Zhou, Maya Talukdar, Michael B Miller, Brian Chhouk, Liz Enyenihi, Ila Rosen, Edward Stronge, Boxun Zhao, Dachan Kim, Jaejoon Choi, Sattar Khoshkhoo, Junho Kim, Javier Ganz, Kyle Travaglini, Mariano Gabitto, Rebecca Hodge, Eitan Kaplan, Ed Lein, Philip L De Jager, David A Bennett, Eunjung Alice Lee, Christopher A Wals. Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer's disease microglia. bioRxiv : the preprint server for biology. 2024-01-23. PMID:38260600. |
somatic cancer driver mutations are enriched and associated with inflammatory states in alzheimer's disease microglia. |
2024-01-23 |
2024-01-25 |
Not clear |
| Song-I Seol, Dashdulam Davaanyam, Sang-A Oh, Eun-Hwa Lee, Pyung-Lim Han, Seung-Woo Kim, Ja-Kyeong Le. Age-Dependent and Aβ-Induced Dynamic Changes in the Subcellular Localization of HMGB1 in Neurons and Microglia in the Brains of an Animal Model of Alzheimer's Disease. Cells. vol 13. issue 2. 2024-01-22. PMID:38247880. |
age-dependent and aβ-induced dynamic changes in the subcellular localization of hmgb1 in neurons and microglia in the brains of an animal model of alzheimer's disease. |
2024-01-22 |
2024-01-24 |
mouse |
| Jessica Sarahi Alavez-Rubio, Teresa Juarez-Cedill. Microglia as a Possible Alternative Therapeutic for Dementia. Journal of Alzheimer's disease reports. vol 8. issue 1. 2024-01-17. PMID:38229830. |
microglia, the resident macrophage tissues in the central nervous system, play a significant role in neuroinflammation and play an important role in amyloid-β clearance in the brain, and impaired microglial clearance of amyloid-β has also been shown to be involved in the pathogenesis of alzheimer's disease. |
2024-01-17 |
2024-01-19 |
Not clear |
| Nunzio Pomara, Bruno Pietro Imbimb. Do anti-Aβ monoclonal antibodies lower brain plaques in Alzheimer patients through microglia activation? Alzheimer's & dementia : the journal of the Alzheimer's Association. 2024-01-15. PMID:38224269. |
do anti-aβ monoclonal antibodies lower brain plaques in alzheimer patients through microglia activation? |
2024-01-15 |
2024-01-17 |
Not clear |