| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shwetha Nanjundaiah, Hariharakrishnan Chidambaram, Madhura Chandrashekar, Subashchandrabose Chinnathamb. Role of Microglia in Regulating Cholesterol and Tau Pathology in Alzheimer's Disease. Cellular and molecular neurobiology. vol 41. issue 4. 2021-10-06. PMID:32468440. |
role of microglia in regulating cholesterol and tau pathology in alzheimer's disease. |
2021-10-06 |
2023-08-13 |
Not clear |
| Qingqin S Li, Louis De Muync. Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1. Brain, behavior, & immunity - health. vol 13. 2021-10-01. PMID:34589742. |
differentially expressed genes in alzheimer's disease highlighting the roles of microglia genes including olr1 and astrocyte gene cdk2ap1. |
2021-10-01 |
2023-08-13 |
Not clear |
| Alexandra L Matthews, Chek Ziu Koo, Justyna Szyroka, Neale Harrison, Aditi Kanhere, Michael G Tomlinso. Regulation of Leukocytes by TspanC8 Tetraspanins and the "Molecular Scissor" ADAM10. Frontiers in immunology. vol 9. 2021-09-24. PMID:30013551. |
on microglia, increased adam10 cleavage of a rare variant of the scavenger receptor triggering receptor expressed on myeloid cells 2 may increase susceptibility to alzheimer's disease. |
2021-09-24 |
2023-08-13 |
mouse |
| Norwin Kubick, Patrick C Henckell Flournoy, Pavel Klimovich, Gina Manda, Michel-Edwar Mickae. What has single-cell RNA sequencing revealed about microglial neuroimmunology? Immunity, inflammation and disease. vol 8. issue 4. 2021-09-24. PMID:33085226. |
the review then summarizes the current knowledge gained using scrna-seq in the field of microglia, including novel subpopulations associated with function and development under homeostasis as well during several pathological conditions such as alzheimer, lipopolysaccharide response, and hiv in relation to the methods employed. |
2021-09-24 |
2023-08-13 |
Not clear |
| Madeleine R Brown, Sheena E Radford, Eric W Hewit. Modulation of β-Amyloid Fibril Formation in Alzheimer's Disease by Microglia and Infection. Frontiers in molecular neuroscience. vol 13. 2021-09-24. PMID:33324164. |
modulation of β-amyloid fibril formation in alzheimer's disease by microglia and infection. |
2021-09-24 |
2023-08-13 |
Not clear |
| Barbara Rossi, Bruno Santos-Lima, Eleonora Terrabuio, Elena Zenaro, Gabriela Constanti. Common Peripheral Immunity Mechanisms in Multiple Sclerosis and Alzheimer's Disease. Frontiers in immunology. vol 12. 2021-09-20. PMID:33679799. |
both multiple sclerosis (ms) and alzheimer's disease (ad) are characterized by infiltrating immune cells, activated microglia, astrocyte proliferation, and neuronal damage. |
2021-09-20 |
2023-08-13 |
Not clear |
| Barbara Blicher Thomsen, Cecilie Madsen, Katrine Tækker Krohn, Camilla Thygesen, Trine Schütt, Athanasios Metaxas, Sultan Darvesh, Jørgen Steen Agerholm, Martin Wirenfeldt, Mette Berendt, Bente Finse. Mild Microglial Responses in the Cortex and Perivascular Macrophage Infiltration in Subcortical White Matter in Dogs with Age-Related Dementia Modelling Prodromal Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 82. issue 2. 2021-09-20. PMID:34057083. |
microglia contribute to alzheimer's disease (ad) pathogenesis by clearing amyloid-β (aβ) and driving neuroinflammation. |
2021-09-20 |
2023-08-13 |
Not clear |
| Tasuku Araki, Yuji Ikegaya, Ryuta Koyam. The effects of microglia- and astrocyte-derived factors on neurogenesis in health and disease. The European journal of neuroscience. vol 54. issue 5. 2021-09-17. PMID:32920880. |
whereas, under pathological conditions such as alzheimer's disease, depression, and epilepsy, microglia and astrocytes play a leading role in inflammation and are involved in attenuating the normal process of neurogenesis. |
2021-09-17 |
2023-08-13 |
Not clear |
| Wolfgang J Streit, Habibeh Khoshbouei, Ingo Bechman. The Role of Microglia in Sporadic Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 79. issue 3. 2021-09-17. PMID:33361603. |
the role of microglia in sporadic alzheimer's disease. |
2021-09-17 |
2023-08-13 |
human |
| Wolfgang J Streit, Habibeh Khoshbouei, Ingo Bechman. The Role of Microglia in Sporadic Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 79. issue 3. 2021-09-17. PMID:33361603. |
microglia constitute the brain's immune system and their involvement in alzheimer's disease has been discussed. |
2021-09-17 |
2023-08-13 |
human |
| Chao Ma, Jerry B Hunt, Andrii Kovalenko, Huimin Liang, Maj-Linda B Selenica, Michael B Orr, Bei Zhang, John C Gensel, David J Feola, Marcia N Gordon, Dave Morgan, Paula C Bickford, Daniel C Le. Myeloid Arginase 1 Insufficiency Exacerbates Amyloid-β Associated Neurodegenerative Pathways and Glial Signatures in a Mouse Model of Alzheimer's Disease: A Targeted Transcriptome Analysis. Frontiers in immunology. vol 12. 2021-09-15. PMID:34046031. |
brain myeloid cells, include infiltrating macrophages and resident microglia, play an essential role in responding to and inducing neurodegenerative diseases, such as alzheimer's disease (ad). |
2021-09-15 |
2023-08-13 |
mouse |
| Lechan Tao, Qi Liu, Fuli Zhang, Yuting Fu, Xi Zhu, Xiaofu Weng, Hongbin Han, Yong Huang, Yuanzhen Suo, Liang Chen, Xiaoling Gao, Xunbin We. Microglia modulation with 1070-nm light attenuates Aβ burden and cognitive impairment in Alzheimer's disease mouse model. Light, science & applications. vol 10. issue 1. 2021-09-15. PMID:34493703. |
microglia modulation with 1070-nm light attenuates aβ burden and cognitive impairment in alzheimer's disease mouse model. |
2021-09-15 |
2023-08-13 |
mouse |
| Olivia G Holloway, Anna E King, Jenna M Ziebel. Microglia Demonstrate Local Mixed Inflammation and a Defined Morphological Shift in an APP/PS1 Mouse Model. Journal of Alzheimer's disease : JAD. vol 77. issue 4. 2021-09-10. PMID:32894243. |
microglia are traditionally described as the immune cells of the brain and have an inflammatory role in alzheimer's disease (ad). |
2021-09-10 |
2023-08-13 |
mouse |
| Susan Fung, Carole L Smith, Katherine E Prater, Amanda Case, Kevin Green, Leah Osnis, Chloe Winston, Yoshito Kinoshita, Bryce Sopher, Richard S Morrison, Gwenn A Garden, Suman Jayade. Early-Onset Familial Alzheimer Disease Variant PSEN2 N141I Heterozygosity is Associated with Altered Microglia Phenotype. Journal of Alzheimer's disease : JAD. vol 77. issue 2. 2021-09-09. PMID:32741831. |
early-onset familial alzheimer disease variant psen2 n141i heterozygosity is associated with altered microglia phenotype. |
2021-09-09 |
2023-08-13 |
Not clear |
| Tongya Yu, Hui Quan, Yuzhen Xu, Yunxiao Dou, Feihong Wang, Yingying Lin, Xue Qi, Yanxin Zhao, Xueyuan Li. A Neural plasticity. vol 2020. 2021-09-09. PMID:33029126. |
a compelling evidence from basic molecular biology has demonstrated the crucial role of microglia in the pathogenesis of alzheimer's disease (ad). |
2021-09-09 |
2023-08-13 |
Not clear |
| Tongya Yu, Hui Quan, Yuzhen Xu, Yunxiao Dou, Feihong Wang, Yingying Lin, Xue Qi, Yanxin Zhao, Xueyuan Li. A Neural plasticity. vol 2020. 2021-09-09. PMID:33029126. |
microglia were believed to play a dual role in both promoting and inhibiting alzheimer's disease progression. |
2021-09-09 |
2023-08-13 |
Not clear |
| Sahar S Alghamdi, Suni M Mustafa, Bob M Moore I. Synthesis and biological evaluation of a ring analogs of the selective CB2 inverse agonist SMM-189. Bioorganic & medicinal chemistry. vol 33. 2021-09-08. PMID:33550084. |
microglia are the principle cell type driving sustained neuroinflammation in neurodegenerative diseases such as alzheimer's, parkinson's, and multiple sclerosis. |
2021-09-08 |
2023-08-13 |
Not clear |
| Juan Ramón Perea, Marta Bolós, Jesús Avil. Microglia in Alzheimer's Disease in the Context of Tau Pathology. Biomolecules. vol 10. issue 10. 2021-09-07. PMID:33066368. |
microglia in alzheimer's disease in the context of tau pathology. |
2021-09-07 |
2023-08-13 |
Not clear |
| Juan Ramón Perea, Marta Bolós, Jesús Avil. Microglia in Alzheimer's Disease in the Context of Tau Pathology. Biomolecules. vol 10. issue 10. 2021-09-07. PMID:33066368. |
however, the latest advances have revealed the complexity and importance of microglia in neurodegenerative conditions such as alzheimer's disease (ad), the most common form of dementia associated with aging. |
2021-09-07 |
2023-08-13 |
Not clear |
| Michael Fassler, Maya Saban Rappaport, Clara Benaim Cuño, Jacob Georg. Engagement of TREM2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in Alzheimer's disease models. Journal of neuroinflammation. vol 18. issue 1. 2021-09-07. PMID:33422057. |
engagement of trem2 by a novel monoclonal antibody induces activation of microglia and improves cognitive function in alzheimer's disease models. |
2021-09-07 |
2023-08-13 |
Not clear |