All Relations between Alzheimer Disease and microglial cell

Publication Sentence Publish Date Extraction Date Species
Miaoping Zhang, Chunmei Liang, Xiongjin Chen, Yujie Cai, Lili Cu. Interplay between microglia and environmental risk factors in Alzheimer's disease. Neural regeneration research. vol 19. issue 8. 2023-12-16. PMID:38103237. interplay between microglia and environmental risk factors in alzheimer's disease. 2023-12-16 2023-12-19 Not clear
Miaoping Zhang, Chunmei Liang, Xiongjin Chen, Yujie Cai, Lili Cu. Interplay between microglia and environmental risk factors in Alzheimer's disease. Neural regeneration research. vol 19. issue 8. 2023-12-16. PMID:38103237. microglia, the most important brain immune cells, play a central role in alzheimer's disease pathogenesis and are considered environmental and lifestyle "sensors." 2023-12-16 2023-12-19 Not clear
Miaoping Zhang, Chunmei Liang, Xiongjin Chen, Yujie Cai, Lili Cu. Interplay between microglia and environmental risk factors in Alzheimer's disease. Neural regeneration research. vol 19. issue 8. 2023-12-16. PMID:38103237. however, the specific mechanisms underlying interactions among these factors and microglia in alzheimer's disease are unclear. 2023-12-16 2023-12-19 Not clear
Miaoping Zhang, Chunmei Liang, Xiongjin Chen, Yujie Cai, Lili Cu. Interplay between microglia and environmental risk factors in Alzheimer's disease. Neural regeneration research. vol 19. issue 8. 2023-12-16. PMID:38103237. herein, we: discuss the biological effects of air pollution, chronic stress, gut microbiota, sleep patterns, physical exercise, cigarette smoking, and caffeine consumption on microglia; consider how unhealthy lifestyle factors influence individual susceptibility to alzheimer's disease; and present the neuroprotective effects of a healthy lifestyle. 2023-12-16 2023-12-19 Not clear
Miaoping Zhang, Chunmei Liang, Xiongjin Chen, Yujie Cai, Lili Cu. Interplay between microglia and environmental risk factors in Alzheimer's disease. Neural regeneration research. vol 19. issue 8. 2023-12-16. PMID:38103237. toward intervening and controlling these environmental risk factors at an early alzheimer's disease stage, understanding the role of microglia in alzheimer's disease development, and targeting strategies to target microglia, could be essential to future alzheimer's disease treatments. 2023-12-16 2023-12-19 Not clear
Jin-Jing Wu, Zhe We. Advances in the study of the effects of gut microflora on microglia in Alzheimer's disease. Frontiers in molecular neuroscience. vol 16. 2023-12-15. PMID:38098943. advances in the study of the effects of gut microflora on microglia in alzheimer's disease. 2023-12-15 2023-12-17 Not clear
Philip Regan, Katriona L Hole, Julia Sero, Robert J William. Epigallocatechin Gallate Modulates Microglia Phenotype to Suppress Pro-inflammatory Signalling Cues and Inhibit Phagocytosis. Molecular neurobiology. 2023-12-14. PMID:38095777. microglia are crucial players in the pathogenesis of late-onset alzheimer's disease (ad), with evidence for both deleterious and beneficial effects. 2023-12-14 2023-12-17 Not clear
Jack Humphrey, Erica Brophy, Roman Kosoy, Biao Zeng, Elena Coccia, Daniele Mattei, Ashvin Ravi, Anastasia G Efthymiou, Elisa Navarro, Benjamin Z Muller, Gijsje Jlj Snijders, Amanda Allan, Alexandra Münch, Reta Birhanu Kitata, Steven P Kleopoulos, Stathis Argyriou, Zhiping Shao, Nancy Francoeur, Chia-Feng Tsai, Marina A Gritsenko, Matthew E Monroe, Vanessa L Paurus, Karl K Weitz, Tujin Shi, Robert Sebra, Tao Liu, Lot D de Witte, Alison M Goate, David A Bennett, Vahram Haroutunian, Gabriel E Hoffman, John F Fullard, Panos Roussos, Towfique Ra. Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing. medRxiv : the preprint server for health sciences. 2023-12-11. PMID:38076956. we then quantified the expression of both known and novel isoforms in a multi-ethnic meta-analysis of 555 human microglia short-read rna-seq samples from 391 donors, the largest to date, and found associations with genetic risk loci in alzheimer's disease and parkinson's disease. 2023-12-11 2023-12-17 human
Rebecca Ferrisi, Francesca Gado, Caterina Ricardi, Beatrice Polini, Clementina Manera, Grazia Chiellin. The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer's Disease. Journal of clinical medicine. vol 12. issue 23. 2023-12-09. PMID:38068253. the interplay between cannabinoid receptors and microglia in the pathophysiology of alzheimer's disease. 2023-12-09 2023-12-17 Not clear
Andrea Amerio, Luca Magnani, Gabriele Arduino, Fabio Fesce, Renato de Filippis, Alberto Parise, Alessandra Costanza, Khoa D Nguyen, Daniele Saverino, Domenico De Berardis, Andrea Aguglia, Andrea Escelsior, Gianluca Serafini, Pasquale De Fazio, Mario Amor. Immunomodulatory Effects of Clozapine: More Than Just a Side Effect in Schizophrenia. Current neuropharmacology. 2023-12-04. PMID:38031778. several studies are concurrently highlighting the importance of microglia, the resident immune cells of the central nervous system, in a huge number of neurodegenerative diseases, including multiple sclerosis, alzheimer's and parkinson's diseases, as well as ssds. 2023-12-04 2023-12-10 Not clear
Qiuchen Zhao, Megi Maci, Morgan R Miller, Heng Zhou, Fang Zhang, Moustafa Algamal, Yee Fun Lee, Steven S Hou, Stephen J Perle, Hoang Le, Alyssa N Russ, Eng H Lo, Dmitry Gerashchenko, Stephen N Gomperts, Brian J Bacskai, Ksenia V Kastanenk. Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model. Molecular neurodegeneration. vol 18. issue 1. 2023-12-02. PMID:38041158. sleep restoration by optogenetic targeting of gabaergic neurons reprograms microglia and ameliorates pathological phenotypes in an alzheimer's disease model. 2023-12-02 2023-12-10 Not clear
Wendi Huang, Juan Huang, Nanqu Huang, Yong Lu. The role of TREM2 in Alzheimer's disease: from the perspective of Tau. Frontiers in cell and developmental biology. vol 11. 2023-12-01. PMID:38020891. triggering receptor expressed on myeloid cells 2 (trem2), a pattern recognition receptor abundantly expressed on microglia, has been identified as one of the risk factors for alzheimer's disease (ad). 2023-12-01 2023-12-10 Not clear
Vicky Chou, Richard V Pearse, Aimee J Aylward, Nancy Ashour, Mariko Taga, Gizem Terzioglu, Masashi Fujita, Seeley B Fancher, Alina Sigalov, Courtney R Benoit, Hyo Lee, Matti Lam, Nicholas T Seyfried, David A Bennett, Philip L De Jager, Vilas Menon, Tracy L Young-Pears. INPP5D regulates inflammasome activation in human microglia. Nature communications. vol 14. issue 1. 2023-11-30. PMID:38016942. microglia and neuroinflammation play an important role in the development and progression of alzheimer's disease (ad). 2023-11-30 2023-12-07 human
Gizem Terzioglu, Tracy L Young-Pears. Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease. Molecular neurodegeneration. vol 18. issue 1. 2023-11-30. PMID:38017562. recent genetic studies on alzheimer's disease (ad) have brought microglia under the spotlight, as loci associated with ad risk are enriched in genes expressed in microglia. 2023-11-30 2023-12-07 human
Hyun-Sik Yang, Ling Teng, Daniel Kang, Vilas Menon, Tian Ge, Hilary K Finucane, Aaron P Schultz, Michael Properzi, Hans-Ulrich Klein, Lori B Chibnik, Julie A Schneider, David A Bennett, Timothy J Hohman, Richard P Mayeux, Keith A Johnson, Philip L De Jager, Reisa A Sperlin. Cell-type-specific Alzheimer's disease polygenic risk scores are associated with distinct disease processes in Alzheimer's disease. Nature communications. vol 14. issue 1. 2023-11-30. PMID:38036535. many of the alzheimer's disease (ad) risk genes are specifically expressed in microglia and astrocytes, but how and when the genetic risk localizing to these cell types contributes to ad pathophysiology remains unclear. 2023-11-30 2023-12-10 human
Wendi Huang, Juan Huang, Nanqu Huang, Yong Lu. The role of TREM2 in Alzheimer's disease: from the perspective of Tau. Frontiers in cell and developmental biology. vol 11. 2023-12-01. PMID:38020891. triggering receptor expressed on myeloid cells 2 (trem2), a pattern recognition receptor abundantly expressed on microglia, has been identified as one of the risk factors for alzheimer's disease (ad). 2023-11-29 2023-12-10 Not clear
Gizem Terzioglu, Tracy L Young-Pears. Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease. Molecular neurodegeneration. vol 18. issue 1. 2023-11-30. PMID:38017562. recent genetic studies on alzheimer's disease (ad) have brought microglia under the spotlight, as loci associated with ad risk are enriched in genes expressed in microglia. 2023-11-29 2023-12-07 human
Madison K Kuhn, Yerbol Tagay, Erdem D Tabdanov, Irina A Elcheva, Elizabeth A Procto. Dynamic neuroinflammatory profiles predict Alzheimer's disease pathology in microglia-containing cerebral organoids. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014053. neuroinflammation and the underlying dysregulated immune responses of microglia actively contribute to the progression and, likely, the initiation of alzheimer's disease (ad). 2023-11-28 2023-11-29 human
Antara Rao, Nuo Chen, Min Joo Kim, Jessica Blumenfeld, Oscar Yip, Yanxia Hao, Zherui Liang, Maxine R Nelson, Nicole Koutsodendris, Brian Grone, Leo Ding, Seo Yeon Yoon, Patrick Arriola, Yadong Huan. Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer's Disease Model. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014339. microglia depletion reduces human neuronal apoe4-driven pathologies in a chimeric alzheimer's disease model. 2023-11-28 2023-11-29 mouse
Antara Rao, Nuo Chen, Min Joo Kim, Jessica Blumenfeld, Oscar Yip, Yanxia Hao, Zherui Liang, Maxine R Nelson, Nicole Koutsodendris, Brian Grone, Leo Ding, Seo Yeon Yoon, Patrick Arriola, Yadong Huan. Microglia Depletion Reduces Human Neuronal APOE4-Driven Pathologies in a Chimeric Alzheimer's Disease Model. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014339. despite strong evidence supporting the involvement of both apolipoprotein e4 (apoe4) and microglia in alzheimer's disease (ad) pathogenesis, the effects of microglia on neuronal apoe4-driven ad pathogenesis remain elusive. 2023-11-28 2023-11-29 mouse