| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Danielle S Davies, Jolande Ma, Thuvarahan Jegathees, Claire Goldsbur. Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease. Brain pathology (Zurich, Switzerland). vol 27. issue 6. 2018-01-26. PMID:27862631. |
changes in microglia function are involved in alzheimer's disease (ad) for which ageing is the major risk factor. |
2018-01-26 |
2023-08-13 |
human |
| Souvarish Sarkar, Emir Malovic, Brandon Plante, Gary Zenitsky, Huajun Jin, Vellareddy Anantharam, Arthi Kanthasamy, Anumantha G Kanthasam. Rapid and Refined CD11b Magnetic Isolation of Primary Microglia with Enhanced Purity and Versatility. Journal of visualized experiments : JoVE. issue 122. 2018-01-18. PMID:28447995. |
the classical (m1-type) and alternative (m2-type) activations of macrophages have also been extended to microglia in an effort to better understand the underlying interplay these phenotypes have in neuroinflammatory conditions such as parkinson's, alzheimer's, and huntington's diseases. |
2018-01-18 |
2023-08-13 |
Not clear |
| Young Jin Jeong, Hyun Jin Yoon, Do-Young Kan. Assessment of change in glucose metabolism in white matter of amyloid-positive patients with Alzheimer disease using F-18 FDG PET. Medicine. vol 96. issue 48. 2018-01-16. PMID:29310421. |
in alzheimer disease (ad), neuroinflammation is an important process related to the deposition of beta-amyloid plaques and the activation of microglia. |
2018-01-16 |
2023-08-13 |
human |
| Knut Bibe. Reestablishing microglia function: good news for Alzheimer's therapy? The EMBO journal. vol 36. issue 5. 2018-01-08. PMID:28213481. |
reestablishing microglia function: good news for alzheimer's therapy? |
2018-01-08 |
2023-08-13 |
Not clear |
| Sung Hoon Baik, Seokjo Kang, Sung Min Son, Inhee Mook-Jun. Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model. Glia. vol 64. issue 12. 2018-01-05. PMID:27658617. |
microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of alzheimer's disease mouse model. |
2018-01-05 |
2023-08-13 |
mouse |
| Paul D Wes, Faten A Sayed, Frédérique Bard, Li Ga. Targeting microglia for the treatment of Alzheimer's Disease. Glia. vol 64. issue 10. 2018-01-02. PMID:27100611. |
targeting microglia for the treatment of alzheimer's disease. |
2018-01-02 |
2023-08-13 |
Not clear |
| Paul D Wes, Faten A Sayed, Frédérique Bard, Li Ga. Targeting microglia for the treatment of Alzheimer's Disease. Glia. vol 64. issue 10. 2018-01-02. PMID:27100611. |
while histological changes in microglia have long been recognized as a pathological feature of alzheimer's disease (ad), recent genetic association studies have also strongly implicated microglia in the etiology of the disease. |
2018-01-02 |
2023-08-13 |
Not clear |
| Ayman ElAli, Serge Rives. Microglia in Alzheimer's disease: A multifaceted relationship. Brain, behavior, and immunity. vol 55. 2017-12-29. PMID:26254232. |
microglia in alzheimer's disease: a multifaceted relationship. |
2017-12-29 |
2023-08-13 |
Not clear |
| Ling Xu, Dan He, Ying Ba. Microglia-Mediated Inflammation and Neurodegenerative Disease. Molecular neurobiology. vol 53. issue 10. 2017-12-29. PMID:26659872. |
activated microglia were found surrounding lesions of various neurodegenerative diseases, such as alzheimer's disease, parkinson's disease, muscular amyotrophic lateral sclerosis, and multiple sclerosis. |
2017-12-29 |
2023-08-13 |
Not clear |
| Marc Suárez-Calvet, Miguel Ángel Araque Caballero, Gernot Kleinberger, Randall J Bateman, Anne M Fagan, John C Morris, Johannes Levin, Adrian Danek, Michael Ewers, Christian Haas. Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury. Science translational medicine. vol 8. issue 369. 2017-12-29. PMID:27974666. |
emerging evidence supports a role for innate immunity and microglia in alzheimer's disease (ad) pathophysiology. |
2017-12-29 |
2023-08-13 |
human |
| Monica Molteni, Carlo Rossett. Neurodegenerative diseases: The immunological perspective. Journal of neuroimmunology. vol 313. 2017-11-29. PMID:29153601. |
increasing evidence supports the notion that the neurodegenerative process occurring in alzheimer's disease (ad), parkinson's disease (pd) and amyotrophic lateral sclerosis (als) does not only imply the neuronal compartment but also involves a strong interaction with the immunological cells of the central nervous system (cns), primarily microglia. |
2017-11-29 |
2023-08-13 |
Not clear |
| Zhuoran Yin, Divya Raj, Nasrin Saiepour, Debby Van Dam, Nieske Brouwer, Inge R Holtman, Bart J L Eggen, Thomas Möller, Joseph A Tamm, Aicha Abdourahman, Elly M Hol, Willem Kamphuis, Thomas A Bayer, Peter P De Deyn, Erik Boddek. Immune hyperreactivity of Aβ plaque-associated microglia in Alzheimer's disease. Neurobiology of aging. vol 55. 2017-11-28. PMID:28434692. |
immune hyperreactivity of aβ plaque-associated microglia in alzheimer's disease. |
2017-11-28 |
2023-08-13 |
mouse |
| Diego Calderon, Anand Bhaskar, David A Knowles, David Golan, Towfique Raj, Audrey Q Fu, Jonathan K Pritchar. Inferring Relevant Cell Types for Complex Traits by Using Single-Cell Gene Expression. American journal of human genetics. vol 101. issue 5. 2017-11-28. PMID:29106824. |
we discovered a significant association between microglia and late-onset alzheimer disease and an association between schizophrenia and oligodendrocytes and replicating fetal cortical cells. |
2017-11-28 |
2023-08-13 |
Not clear |
| Jingkao Chen, Wei Yin, Yalin Tu, Shengnan Wang, Xiaohong Yang, Qiuhe Chen, Xiao Zhang, Yifan Han, Rongbiao P. L-F001, a novel multifunctional ROCK inhibitor, suppresses neuroinflammation in vitro and in vivo: Involvement of NF-κB inhibition and Nrf2 pathway activation. European journal of pharmacology. vol 806. 2017-11-17. PMID:28320516. |
microglia and astrocytes are largely responsible for inflammatory injury in the brain of alzheimer's disease (ad). |
2017-11-17 |
2023-08-13 |
Not clear |
| Adam D Bachstetter, Eseosa T Ighodaro, Yasmin Hassoun, Danah Aldeiri, Janna H Neltner, Ela Patel, Erin L Abner, Peter T Nelso. Rod-shaped microglia morphology is associated with aging in 2 human autopsy series. Neurobiology of aging. vol 52. 2017-11-16. PMID:28131016. |
alzheimer's disease-related pathology was found to influence the presence of rod-shaped microglia, but only in the parietal cortex and not in the hippocampus or temporal cortex. |
2017-11-16 |
2023-08-13 |
human |
| Chen-Zhuo Feng, Jin-Bo Yin, Jian-Jun Yang, Lin Ca. Regulatory factor X1 depresses ApoE-dependent Aβ uptake by miRNA-124 in microglial response to oxidative stress. Neuroscience. vol 344. 2017-11-09. PMID:28003160. |
decreased proteolytic clearance of soluble amyloid β (aβ) in microglia affects aβ accumulation on alzheimer's disease progression. |
2017-11-09 |
2023-08-13 |
Not clear |
| Yousef Sawikr, Nagendra Sastry Yarla, Ilaria Peluso, Mohammad Amjad Kamal, Gjumrakch Aliev, Anupam Bishaye. Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals. Advances in protein chemistry and structural biology. vol 108. 2017-10-30. PMID:28427563. |
brain inflammation, characterized by increased microglia and astrocyte activation, increases during aging and is a key feature of neurodegenerative diseases, such as alzheimer's disease (ad). |
2017-10-30 |
2023-08-13 |
Not clear |
| Sami Piirainen, Andrew Youssef, Cai Song, Allan V Kalueff, Gary E Landreth, Tarja Malm, Li Tia. Psychosocial stress on neuroinflammation and cognitive dysfunctions in Alzheimer's disease: the emerging role for microglia? Neuroscience and biobehavioral reviews. vol 77. 2017-10-26. PMID:28185874. |
psychosocial stress on neuroinflammation and cognitive dysfunctions in alzheimer's disease: the emerging role for microglia? |
2017-10-26 |
2023-08-13 |
Not clear |
| Anna A Pimenova, Edoardo Marcora, Alison M Goat. A Tale of Two Genes: Microglial Apoe and Trem2. Immunity. vol 47. issue 3. 2017-10-26. PMID:28930654. |
microglial cell function is implicated in the etiology of alzheimer's disease by human genetics. |
2017-10-26 |
2023-08-13 |
human |
| Heela Sarlus, Michael T Henek. Microglia in Alzheimer's disease. The Journal of clinical investigation. vol 127. issue 9. 2017-10-24. PMID:28862638. |
microglia in alzheimer's disease. |
2017-10-24 |
2023-08-13 |
Not clear |