| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gwenn S Smith, Hiroto Kuwabara, Haijuan Yan, Najlla Nassery, Mark Yoon, Vidya Kamath, Michael Kraut, Neda F Gould, Alena Savonenko, Jennifer Coughlin, Martin Lodge, Martin Pomper, Ayon Nandi, Daniel Holt, Robert F Dannals, Jeannie M Leoutsako. Serotonin Degeneration and Amyloid-β Deposition in Mild Cognitive Impairment: Relationship to Cognitive Deficits. Journal of Alzheimer's disease : JAD. 2023-09-18. PMID:37718818. |
neuropathological and neuroimaging studies have demonstrated degeneration of the serotonin system in alzheimer's disease (ad). |
2023-09-18 |
2023-10-07 |
mouse |
| Aaron Del Pozo, Kevin M Knox, Leanne Lehmann, Stephanie Davidson, Suman Jayadev, Melissa Barker-Halisk. Chronic seizure-induced serotonin pathway dysregulation coincides with mortality in Alzheimer's disease mouse models. bioRxiv : the preprint server for biology. 2023-01-30. PMID:36711965. |
chronic seizure-induced serotonin pathway dysregulation coincides with mortality in alzheimer's disease mouse models. |
2023-01-30 |
2023-08-14 |
mouse |
| Gwenn S Smith, Hillary Protas, Hiroto Kuwabara, Alena Savonenko, Najlla Nassery, Neda F Gould, Michael Kraut, Dimitri Avramopoulos, Daniel Holt, Robert F Dannals, Ayon Nandi, Yi Su, Eric M Reiman, Kewei Che. Molecular imaging of the association between serotonin degeneration and beta-amyloid deposition in mild cognitive impairment. NeuroImage. Clinical. vol 37. 2023-01-21. PMID:36680976. |
degeneration of the serotonin system has been observed in alzheimer's disease (ad) and in mild cognitive impairment (mci). |
2023-01-21 |
2023-08-14 |
mouse |
| Kyu-Ho Shim, Sungchan Ha, Jin Seung Choung, Jee In Choi, Daniel Youngsuk Kim, Jong Moon Kim, MinYoung Ki. Therapeutic Effect of Erythropoietin on Alzheimer's Disease by Activating the Serotonin Pathway. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897720. |
therapeutic effect of erythropoietin on alzheimer's disease by activating the serotonin pathway. |
2022-07-28 |
2023-08-14 |
mouse |
| Gwenn S Smith, Frederick S Barrett, Jin Hui Joo, Najlla Nassery, Alena Savonenko, Devin J Sodums, Christopher M Marano, Cynthia A Munro, Jason Brandt, Michael A Kraut, Yun Zhou, Dean F Wong, Clifford I Workma. Molecular imaging of serotonin degeneration in mild cognitive impairment. Neurobiology of disease. vol 105. 2018-04-18. PMID:28511918. |
neuropathological and neuroimaging studies have consistently demonstrated degeneration of monoamine systems, especially the serotonin system, in normal aging and alzheimer's disease. |
2018-04-18 |
2023-08-13 |
human |
| Seethalakshmi Ramanathan, Stephen J Glat. Serotonergic system genes in psychosis of Alzheimer dementia: meta-analysis. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 17. issue 10. 2010-01-28. PMID:19910872. |
the authors attempted to understand the role of two serotonin system genes, htr2a and slc6a4, on psychosis associated with alzheimer dementia (ad). |
2010-01-28 |
2023-08-12 |
Not clear |
| J K Cooper, D Munga. Serotonin response in sweet-food craving Alzheimer's disease subjects. Aging (Milan, Italy). vol 4. issue 2. 1992-09-18. PMID:1504133. |
using the fenfluramine stimulation test, brain serotonin system response was evaluated in 12 subjects with probable alzheimer's disease. |
1992-09-18 |
2023-08-11 |
human |
| J K Cooper, D Munga. Serotonin response in sweet-food craving Alzheimer's disease subjects. Aging (Milan, Italy). vol 4. issue 2. 1992-09-18. PMID:1504133. |
allowing for assumptions concerning central nervous system regulatory processes, the data suggest a possible role for the serotonin system in sweet-food craving in alzheimer's disease. |
1992-09-18 |
2023-08-11 |
human |
| L S Schneider, J A Severson, H C Chui, V E Pollock, R B Sloane, E R Fredrickso. Platelet tritiated imipramine binding and MAO activity in Alzheimer's disease patients with agitation and delusions. Psychiatry research. vol 25. issue 3. 1988-12-21. PMID:2847206. |
since serotonin system defects occur in alzheimer's disease (ad), and decreased brain 3h-imipramine binding density, and increased brain and platelet mao activity are reported also, we studied platelet 3h-imipramine binding density (bmax) and platelet mao activity in ad outpatients without antecedent psychiatric disorder. |
1988-12-21 |
2023-08-11 |
human |
| C G Gottfries, T Bartfai, A Carlsson, S Eckernäs, L Svennerhol. Multiple biochemical deficits in both gray and white matter of Alzheimer brains. Progress in neuro-psychopharmacology & biological psychiatry. vol 10. issue 3-5. 1987-02-06. PMID:3797685. |
in the brains from the alzheimer patients a disturbance was found in the 5-ht system in the form of reduced levels of 5-ht and 5-hydroxyindolacetic acid (5-hiaa). |
1987-02-06 |
2023-08-11 |
cat |