| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-hong Jiang, Yi-na Zhang, Xiao-wei Wu, Fang-fang Song, Da-yun Gu. Effect of insulin on the cognizing function and expression of hippocampal Abeta1-40 of rat with Alzheimer disease. Chinese medical journal. vol 121. issue 9. 2008-09-09. PMID:18701049. |
a model of simulated alzheimer's disease (ad) induced by aggregated amyloid protein (abeta(1-40)) was built in wistar rats to observe the behavioral and pathological changes of abeta(1-40) and the effect of hypodermic insulin injected on the function of study and memory and the expression of abeta(1-40) from the ca1 area of the hippocampus. |
2008-09-09 |
2023-08-12 |
rat |
| Mikio Aoki, Inga Volkmann, Lars O Tjernberg, Bengt Winblad, Nenad Bogdanovi. Amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain. Neuroreport. vol 19. issue 11. 2008-08-25. PMID:18596605. |
amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of alzheimer's brain. |
2008-08-25 |
2023-08-12 |
Not clear |
| Mikio Aoki, Inga Volkmann, Lars O Tjernberg, Bengt Winblad, Nenad Bogdanovi. Amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain. Neuroreport. vol 19. issue 11. 2008-08-25. PMID:18596605. |
we investigated whether abeta levels are increased in cornu ammonis 1 pyramidal neurons of alzheimer's disease hippocampus, using laser capture microdissection to isolate the neurons and enzyme-linked immunosorbent assay for quantification. |
2008-08-25 |
2023-08-12 |
Not clear |
| Mikio Aoki, Inga Volkmann, Lars O Tjernberg, Bengt Winblad, Nenad Bogdanovi. Amyloid beta-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimer's brain. Neuroreport. vol 19. issue 11. 2008-08-25. PMID:18596605. |
we speculate that intracellular accumulation of abeta42 increase vulnerability of cornu ammonis 1 pyramidal neurons in alzheimer's disease. |
2008-08-25 |
2023-08-12 |
Not clear |
| Oliver Wirths, Henning Breyhan, Stephanie Schäfer, Christian Roth, Thomas A Baye. Deficits in working memory and motor performance in the APP/PS1ki mouse model for Alzheimer's disease. Neurobiology of aging. vol 29. issue 6. 2008-06-20. PMID:17215062. |
the app/ps1ki mouse model for alzheimer's disease (ad) exhibits robust brain and spinal cord axonal degeneration and hippocampal ca1 neuron loss starting at 6 months of age. |
2008-06-20 |
2023-08-12 |
mouse |
| P K Mukherjee, A Chawla, M S Loayza, N G Baza. Docosanoids are multifunctional regulators of neural cell integrity and fate: significance in aging and disease. Prostaglandins, leukotrienes, and essential fatty acids. vol 77. issue 5-6. 2008-04-23. PMID:18060755. |
the hippocampal ca1 region from alzheimer's disease (ad) patients (rapidly sampled) shows a major reduction in npd1. |
2008-04-23 |
2023-08-12 |
Not clear |
| Catalina Amador-Ortiz, Zeshan Ahmed, Cynthia Zehr, Dennis W Dickso. Hippocampal sclerosis dementia differs from hippocampal sclerosis in frontal lobe degeneration. Acta neuropathologica. vol 113. issue 3. 2007-10-19. PMID:17195931. |
hippocampal sclerosis (hs) is characterized by selective neuronal loss and gliosis in ca1 and the subiculum and has been associated with several disorders, including alzheimer's disease, frontotemporal lobar degeneration with ubiquitin immunoreactive inclusions (ftld-u), vascular dementia and some tauopathies. |
2007-10-19 |
2023-08-12 |
Not clear |
| Yoko Uchida, Shun-ichirou Nakano, Fujiya Gomi, Hiroshi Takahash. Differential regulation of basic helix-loop-helix factors Mash1 and Olig2 by beta-amyloid accelerates both differentiation and death of cultured neural stem/progenitor cells. The Journal of biological chemistry. vol 282. issue 27. 2007-09-17. PMID:17488716. |
despite increased neurogenic differentiation markers in the hippocampal ca1 in alzheimer disease, neurons are not replaced in ca1 and the neocortex in the disease. |
2007-09-17 |
2023-08-12 |
mouse |
| A I Scher, Y Xu, E S C Korf, L R White, P Scheltens, A W Toga, P M Thompson, S W Hartley, M P Witter, D J Valentino, L J Laune. Hippocampal shape analysis in Alzheimer's disease: a population-based study. NeuroImage. vol 36. issue 1. 2007-08-01. PMID:17434756. |
hippocampal atrophy--particularly of the ca1 region--may be useful as a biomarker for alzheimer's disease (ad) or the risk for ad. |
2007-08-01 |
2023-08-12 |
Not clear |
| S W Scheff, D A Price, F A Schmitt, S T DeKosky, E J Mufso. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology. vol 68. issue 18. 2007-05-31. PMID:17470753. |
synaptic alterations in ca1 in mild alzheimer disease and mild cognitive impairment. |
2007-05-31 |
2023-08-12 |
human |
| S W Scheff, D A Price, F A Schmitt, S T DeKosky, E J Mufso. Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology. vol 68. issue 18. 2007-05-31. PMID:17470753. |
to evaluate the total number of synapses in the stratum radiatum (str rad) of the human hippocampal ca1 subfield in individuals with mild alzheimer disease (mad), mild cognitive impairment (mci), or no cognitive impairment (nci) and determine if synapse loss is an early event in the progression of the disease. |
2007-05-31 |
2023-08-12 |
human |
| Milena Damjanac, Agnès Rioux Bilan, Laurence Barrier, Raymond Pontcharraud, Cantereau Anne, Jacques Hugon, Guylène Pag. Fluoro-Jade B staining as useful tool to identify activated microglia and astrocytes in a mouse transgenic model of Alzheimer's disease. Brain research. vol 1128. issue 1. 2007-03-27. PMID:17125750. |
in this study, we analyzed the staining of fluoro-jade b alone or combined with specific markers for detection of glial fibrillary acidic protein (gfap) or activated cd68 microglia in the double app(sl)/ps1 ki transgenic mice of alzheimer's disease (ad), which display a massive neuronal loss in the ca1 region of the hippocampus. |
2007-03-27 |
2023-08-12 |
mouse |
| Kazuhito Noda, Kensuke Sasaki, Kohei Fujimi, Yoshinobu Wakisaka, Yumihiro Tanizaki, Yoshiyuki Wakugawa, Yutaka Kiyohara, Mitsuo Iida, Hisamiti Aizawa, Toru Iwak. Quantitative analysis of neurofibrillary pathology in a general population to reappraise neuropathological criteria for senile dementia of the neurofibrillary tangle type (tangle-only dementia): the Hisayama Study. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 26. issue 6. 2007-02-12. PMID:17203586. |
the average density of nft in ca1 in sd-nft subjects was 115.4 per 100 x field (range 23-247), that in alzheimer disease (ad) subjects was 80.1 (range 1-227), and that in non-demented elderly subjects was 37.2 (range 0-203). |
2007-02-12 |
2023-08-12 |
human |
| Liana G Apostolova, Ivo D Dinov, Rebecca A Dutton, Kiralee M Hayashi, Arthur W Toga, Jeffrey L Cummings, Paul M Thompso. 3D comparison of hippocampal atrophy in amnestic mild cognitive impairment and Alzheimer's disease. Brain : a journal of neurology. vol 129. issue Pt 11. 2006-12-11. PMID:17018552. |
we tested the hypothesis that alzheimer's disease subjects have greater atrophy of the ca1, ca2 and ca3 hippocampal subfields relative to amnestic mci subjects. |
2006-12-11 |
2023-08-12 |
human |
| Jianmin Wu, Xizeng Mao, Tao Cai, Jingchu Luo, Liping We. KOBAS server: a web-based platform for automated annotation and pathway identification. Nucleic acids research. vol 34. issue Web Server issue. 2006-08-29. PMID:16845106. |
we demonstrate the usability of the server by finding statistically enriched pathways in a set of upregulated genes in alzheimer's disease (ad) hippocampal cornu ammonis 1 (ca1). |
2006-08-29 |
2023-08-12 |
Not clear |
| Armin von Gunten, Enikö Kövari, Thierry Bussière, Claire-Bénédicte Rivara, Gabriel Gold, Constantin Bouras, Patrick R Hof, Panteleimon Giannakopoulo. Cognitive impact of neuronal pathology in the entorhinal cortex and CA1 field in Alzheimer's disease. Neurobiology of aging. vol 27. issue 2. 2006-03-14. PMID:16399212. |
cognitive impact of neuronal pathology in the entorhinal cortex and ca1 field in alzheimer's disease. |
2006-03-14 |
2023-08-12 |
Not clear |
| Qin Wang, Randall L Woltjer, P J Cimino, Catherine Pan, Kathleen S Montine, Jing Zhang, Thomas J Montin. Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 19. issue 7. 2005-12-22. PMID:15746184. |
we performed proteomic analysis of neurofibrillary tangles (nfts) obtained by laser capture microdissection from pyramidal neurons in hippocampal sector ca1 in patients with alzheimer disease (ad) using liquid chromatography (lc)-mass spectrometry (ms)/ms. |
2005-12-22 |
2023-08-12 |
Not clear |
| Michael Fountoulakis, George T Tsangaris, Antony Maris, Gert Lube. The rat brain hippocampus proteome. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 819. issue 1. 2005-08-01. PMID:15797529. |
in humans, the ca1 area of hippocampus is one of the first brain areas to display pathology in alzheimer's disease. |
2005-08-01 |
2023-08-12 |
rat |
| Chris Zarow, Harry V Vinters, William G Ellis, Michael W Weiner, Dan Mungas, Lon White, Helena C Chu. Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Annals of neurology. vol 57. issue 6. 2005-07-26. PMID:15929035. |
the cornu ammonis 1 region of the hippocampus (ca1) sector of hippocampus is vulnerable to both alzheimer's disease (ad)-type neurofibrillary degeneration and anoxia-ischemia. |
2005-07-26 |
2023-08-12 |
Not clear |
| Armin von Gunten, Enikö Kövari, Claire-Bénédicte Rivara, Constantin Bouras, Patrick R Hof, Panteleimon Giannakopoulo. Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and CA1 field. Experimental neurology. vol 193. issue 1. 2005-05-24. PMID:15817278. |
stereologic analysis of hippocampal alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and ca1 field. |
2005-05-24 |
2023-08-12 |
Not clear |