| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emrin Horgusluoglu-Moloch, Kwangsik Nho, Shannon L Risacher, Sungeun Kim, Tatiana Foroud, Leslie M Shaw, John Q Trojanowski, Paul S Aisen, Ronald C Petersen, Clifford R Jack, Simon Lovestone, Andrew Simmons, Michael W Weiner, Andrew J Sayki. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease. Neurobiology of aging. vol 60. 2018-01-03. PMID:28941407. |
targeted neurogenesis pathway-based gene analysis identifies adora2a associated with hippocampal volume in mild cognitive impairment and alzheimer's disease. |
2018-01-03 |
2023-08-13 |
human |
| Emrin Horgusluoglu-Moloch, Kwangsik Nho, Shannon L Risacher, Sungeun Kim, Tatiana Foroud, Leslie M Shaw, John Q Trojanowski, Paul S Aisen, Ronald C Petersen, Clifford R Jack, Simon Lovestone, Andrew Simmons, Michael W Weiner, Andrew J Sayki. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease. Neurobiology of aging. vol 60. 2018-01-03. PMID:28941407. |
alzheimer's disease (ad) patients display hippocampal atrophy, memory impairment, and cognitive decline. |
2018-01-03 |
2023-08-13 |
human |
| Brianne A Kent, Ralph E Mistlberge. Sleep and hippocampal neurogenesis: Implications for Alzheimer's disease. Frontiers in neuroendocrinology. vol 45. 2018-01-02. PMID:28249715. |
sleep and hippocampal neurogenesis: implications for alzheimer's disease. |
2018-01-02 |
2023-08-13 |
Not clear |
| A A Thaker, B D Weinberg, W P Dillon, C P Hess, H J Cabral, D A Fleischman, S E Leurgans, D A Bennett, B T Hyman, M S Albert, R J Killiany, B Fischl, A M Dale, R S Desika. Entorhinal Cortex: Antemortem Cortical Thickness and Postmortem Neurofibrillary Tangles and Amyloid Pathology. AJNR. American journal of neuroradiology. vol 38. issue 5. 2018-01-02. PMID:28279988. |
the entorhinal cortex, a critical gateway between the neocortex and hippocampus, is one of the earliest regions affected by alzheimer disease-associated neurofibrillary tangle pathology. |
2018-01-02 |
2023-08-13 |
Not clear |
| Vega García-Escudero, Ricardo Gargini, Patricia Martín-Maestro, Esther García, Ramón García-Escudero, Jesús Avil. Tau mRNA 3'UTR-to-CDS ratio is increased in Alzheimer disease. Neuroscience letters. vol 655. 2018-01-01. PMID:28689927. |
to explain this apparently contradictory result, we studied mapt mrna stoichiometry in coding and non-coding regions, and found that the 3'utr-to-cds ratio was higher in the hippocampus of alzheimer disease patients, with higher tau protein but lower total mrna levels. |
2018-01-01 |
2023-08-13 |
mouse |
| Jia-Hao Sun, Hui-Fu Wang, Xi-Chen Zhu, Wan-Jiang Yu, Chen-Chen Tan, Teng Jiang, Meng-Shan Tan, Lan Tan, Jin-Tai Y. The Impact of UNC5C Genetic Variations on Neuroimaging in Alzheimer's Disease. Molecular neurobiology. vol 53. issue 10. 2017-12-29. PMID:26660111. |
in 812 subjects from the alzheimer's disease neuroimaging initiative (adni) dataset, we explored the genotypes of unc5c loci in the volumes of the hippocampus, parahippocampal gyrus, posterior cingulate gyrus, middle temporal and precuneus, and the thickness of the entorhinal cortex which are measured by magnetic resonance imaging (mri). |
2017-12-29 |
2023-08-13 |
human |
| YuanBo Cui, ShanShan Ma, ChunYan Zhang, Wei Cao, Min Liu, DongPeng Li, PengJu Lv, Qu Xing, RuiNa Qu, Ning Yao, Bo Yang, FangXia Gua. Human umbilical cord mesenchymal stem cells transplantation improves cognitive function in Alzheimer's disease mice by decreasing oxidative stress and promoting hippocampal neurogenesis. Behavioural brain research. vol 320. 2017-12-27. PMID:28007537. |
human umbilical cord mesenchymal stem cells transplantation improves cognitive function in alzheimer's disease mice by decreasing oxidative stress and promoting hippocampal neurogenesis. |
2017-12-27 |
2023-08-13 |
mouse |
| Jason C You, Kavitha Muralidharan, Jin W Park, Iraklis Petrof, Mark S Pyfer, Brian F Corbett, John J LaFrancois, Yi Zheng, Xiaohong Zhang, Carrie A Mohila, Daniel Yoshor, Robert A Rissman, Eric J Nestler, Helen E Scharfman, Jeannie Chi. Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits. Nature medicine. vol 23. issue 11. 2017-12-26. PMID:29035369. |
in alzheimer's disease (ad) and epilepsy, both of which are accompanied by recurrent seizures, the severity of cognitive deficits reflects the degree of calbindin reduction in the hippocampal dentate gyrus (dg). |
2017-12-26 |
2023-08-13 |
mouse |
| Shantell C Nolen, Brian Lee, Shruti Shantharam, Hon J Yu, Lydia Su, John Billimek, Daniela A Bot. The effects of sequential treatments on hippocampal volumes in malignant glioma patients. Journal of neuro-oncology. vol 129. issue 3. 2017-12-21. PMID:27393350. |
the hippocampal volume loss progressed over the next 3 years, and was higher than the one previously reported in alzheimer disease patients. |
2017-12-21 |
2023-08-13 |
Not clear |
| Yan He, Rita C Akumuo, Yuan Yang, Sandra J Hewet. Mice deficient in L-12/15 lipoxygenase show increased vulnerability to 3-nitropropionic acid neurotoxicity. Neuroscience letters. vol 643. 2017-12-19. PMID:28229935. |
considerable evidence supports a contributory role for leukocyte-type 12/15 lipoxygenase (l-12/15 lo) in mediating hippocampal and cortical neuronal injury in models of alzheimer's disease and stroke. |
2017-12-19 |
2023-08-13 |
mouse |
| Diego Mastroeni, Omar M Khdour, Elaine Delvaux, Jennifer Nolz, Gary Olsen, Nicole Berchtold, Carl Cotman, Sidney M Hecht, Paul D Colema. Nuclear but not mitochondrial-encoded oxidative phosphorylation genes are altered in aging, mild cognitive impairment, and Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 13. issue 5. 2017-12-18. PMID:27793643. |
we have comprehensively described the expression profiles of mitochondrial dna and nuclear dna genes that encode subunits of the respiratory oxidative phosphorylation (oxphos) complexes (i-v) in the hippocampus from young controls, age matched, mild cognitively impaired (mci), and alzheimer's disease (ad) subjects. |
2017-12-18 |
2023-08-13 |
human |
| Chaitra Venugopal, Shashank Chandanala, Harish Chandra Prasad, Danish Nayeem, Ramesh R Bhonde, Anandh Dhanushkod. Regenerative therapy for hippocampal degenerative diseases: lessons from preclinical studies. Journal of tissue engineering and regenerative medicine. vol 11. issue 2. 2017-12-14. PMID:26118731. |
amongst these, degenerative diseases involving hippocampus like alzheimer's disease (ad) and temporal lobe epilepsy (tle) are ranked higher as it is vulnerable to excitotoxicity induced neuronal dysfunction and death resulting in cognitive impairment. |
2017-12-14 |
2023-08-13 |
Not clear |
| Zi-Ai Zhao, Ya-Lei Ning, Ping Li, Nan Yang, Yan Peng, Ren-Ping Xiong, Yan Zhao, Dong Liu, Xu-Jia Zeng, Jiang-Fan Chen, Yuan-Guo Zho. Widespread hyperphosphorylated tau in the working memory circuit early after cortical impact injury of brain (Original study). Behavioural brain research. vol 323. 2017-12-13. PMID:28163095. |
given that tau hyperphosphorylation is an important cause of cognitive impairment in patients of alzheimer's disease, our present study detected the presence of hyperphosphorylated tau (p-tau), mainly at ser404, in multiple brain regions, including the ipsilateral parietal cortex, contralateral hippocampus and prefrontal cortex, immediately after the injury in a mouse tbi model; these changes lasted for at least 4w. |
2017-12-13 |
2023-08-13 |
mouse |
| Marc Teichmann, Stéphane Epelbaum, Dalila Samri, Marcel Levy Nogueira, Agnès Michon, Harald Hampel, Foudil Lamari, Bruno Duboi. Free and Cued Selective Reminding Test - accuracy for the differential diagnosis of Alzheimer's and neurodegenerative diseases: A large-scale biomarker-characterized monocenter cohort study (ClinAD). Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 13. issue 8. 2017-12-06. PMID:28222300. |
the international working group recommended the free and cued selective reminding test (fcsrt) as a sensitive detector of the amnesic syndrome of the hippocampal type in typical alzheimer's disease (ad). |
2017-12-06 |
2023-08-13 |
Not clear |
| Dominik Wolf, Martina Bocchetta, Gregory M Preboske, Marina Boccardi, Michel J Groth. Reference standard space hippocampus labels according to the European Alzheimer's Disease Consortium-Alzheimer's Disease Neuroimaging Initiative harmonized protocol: Utility in automated volumetry. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 13. issue 8. 2017-12-06. PMID:28238738. |
reference standard space hippocampus labels according to the european alzheimer's disease consortium-alzheimer's disease neuroimaging initiative harmonized protocol: utility in automated volumetry. |
2017-12-06 |
2023-08-13 |
Not clear |
| Dominik Wolf, Martina Bocchetta, Gregory M Preboske, Marina Boccardi, Michel J Groth. Reference standard space hippocampus labels according to the European Alzheimer's Disease Consortium-Alzheimer's Disease Neuroimaging Initiative harmonized protocol: Utility in automated volumetry. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 13. issue 8. 2017-12-06. PMID:28238738. |
a harmonized protocol (harp) for manual hippocampal segmentation on magnetic resonance imaging (mri) has recently been developed by an international european alzheimer's disease consortium-alzheimer's disease neuroimaging initiative project. |
2017-12-06 |
2023-08-13 |
Not clear |
| Andrea R Zammit, Ali Ezzati, Molly E Zimmerman, Richard B Lipton, Michael L Lipton, Mindy J Kat. Roles of hippocampal subfields in verbal and visual episodic memory. Behavioural brain research. vol 317. 2017-12-05. PMID:27646772. |
selective hippocampal (hc) subfield atrophy has been reported in older adults with mild cognitive impairment and alzheimer's disease. |
2017-12-05 |
2023-08-13 |
Not clear |
| Brenna Cholerton, Adam Omidpanah, Tara M Madhyastha, Thomas J Grabowski, Astrid M Suchy-Dicey, Dean K Shibata, Lonnie A Nelson, Steven P Verney, Barbara V Howard, William T Longstreth, Thomas J Montine, Dedra Buchwal. Total Brain and Hippocampal Volumes and Cognition in Older American Indians: The Strong Heart Study. Alzheimer disease and associated disorders. vol 31. issue 2. 2017-12-04. PMID:28538087. |
estimates of hippocampal volume by magnetic resonance imaging have clinical and cognitive correlations and can assist in early alzheimer disease diagnosis. |
2017-12-04 |
2023-08-13 |
Not clear |
| Rikki Hullinger, Luigi Pugliell. Molecular and cellular aspects of age-related cognitive decline and Alzheimer's disease. Behavioural brain research. vol 322. issue Pt B. 2017-11-30. PMID:27163751. |
the important role of the hippocampus in age-related cognitive decline and in vulnerability to disease processes such as alzheimer's disease has prompted this review, which will focus on the complexity of changes that characterize aging, and on the molecular connections that exist between normal aging and alzheimer's disease. |
2017-11-30 |
2023-08-13 |
Not clear |
| Sarah M Neuner, Lynda A Wilmott, Brian R Hoffmann, Khyobeni Mozhui, Catherine C Kaczorowsk. Hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and Alzheimer's disease mouse models. Behavioural brain research. vol 322. issue Pt B. 2017-11-30. PMID:27265785. |
hippocampal proteomics defines pathways associated with memory decline and resilience in normal aging and alzheimer's disease mouse models. |
2017-11-30 |
2023-08-13 |
mouse |