All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
David S Knopman, Clifford R Jack, Emily S Lundt, Stephen D Weigand, Prashanthi Vemuri, Val J Lowe, Kejal Kantarci, Jeffrey L Gunter, Matthew L Senjem, Michelle M Mielke, Mary M Machulda, Rosebud O Roberts, Bradley F Boeve, David T Jones, Ronald C Peterse. Evolution of neurodegeneration-imaging biomarkers from clinically normal to dementia in the Alzheimer disease spectrum. Neurobiology of aging. vol 46. 2017-09-28. PMID:27460147. pittsburgh compound b (pib) positron emission tomography (pet) was used to select participants in the mayo clinic study of aging and the mayo alzheimer's disease research center with elevated β-amyloid, designated as "a+," and hippocampal volume and (18)fluorodeoxyglucose (fdg) positron emission tomography were used to characterize participants as having evidence of neurodegeneration ("n+") at the baseline evaluation. 2017-09-28 2023-08-13 human
Cândida Dias, Cátia F Lourenço, Elisabete Ferreiro, Rui M Barbosa, João Laranjinha, Ana Led. Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiology of aging. vol 46. 2017-09-28. PMID:27460153. age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of alzheimer's disease: implications for neurometabolic regulation. 2017-09-28 2023-08-13 mouse
Aram Asatryan, Nicolas G Baza. Molecular mechanisms of signaling via the docosanoid neuroprotectin D1 for cellular homeostasis and neuroprotection. The Journal of biological chemistry. vol 292. issue 30. 2017-09-26. PMID:28615451. docosanoids include neuroprotectin d1 (npd1), which is decreased in the ca1 hippocampal area of patients with early-stage alzheimer's disease (ad). 2017-09-26 2023-08-13 Not clear
Matthew D Cykowski, Suzanne Z Powell, Paul E Schulz, Hidehiro Takei, Andreana L Rivera, Robert E Jackson, Gustavo Roman, Gregory A Jicha, Peter T Nelso. Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance With a Focus on Cerebral Age-Related TDP-43 With Sclerosis. Archives of pathology & laboratory medicine. vol 141. issue 8. 2017-09-25. PMID:28467211. hippocampal sclerosis may also be comorbid with frontotemporal lobar degeneration, alzheimer disease, and lewy body disease. 2017-09-25 2023-08-13 Not clear
Christoph Köhle. Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology. Acta neuropathologica. vol 132. issue 3. 2017-09-22. PMID:27062260. granule-containing vacuoles in the cytoplasm of hippocampal neurons are a neuropathological feature of alzheimer's disease. 2017-09-22 2023-08-13 Not clear
Christoph Köhle. Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology. Acta neuropathologica. vol 132. issue 3. 2017-09-22. PMID:27062260. however, several studies have reported much higher numbers of neurons undergoing gvd in the hippocampus of alzheimer's disease cases. 2017-09-22 2023-08-13 Not clear
Alexandra M Nicholson, Rosa Rademaker. What we know about TMEM106B in neurodegeneration. Acta neuropathologica. vol 132. issue 5. 2017-09-20. PMID:27543298. in this manuscript, we review the initial discovery and replication studies describing tmem106b variants as disease risk factors and modifiers in tdp-43 proteinopathies, such as ftld-tdp caused by progranulin (grn) or chromosome 9 open reading frame 72 (c9orf72) mutations, as well as alzheimer's disease and hippocampal sclerosis. 2017-09-20 2023-08-13 Not clear
Elisabeth Sanchez-Mejias, Victoria Navarro, Sebastian Jimenez, Maria Sanchez-Mico, Raquel Sanchez-Varo, Cristina Nuñez-Diaz, Laura Trujillo-Estrada, Jose Carlos Davila, Marisa Vizuete, Antonia Gutierrez, Javier Vitoric. Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration. Acta neuropathologica. vol 132. issue 6. 2017-09-20. PMID:27743026. soluble phospho-tau from alzheimer's disease hippocampus drives microglial degeneration. 2017-09-20 2023-08-13 human
Peter T Nelson, Yuriko Katsumata, Kwangsik Nho, Sergey C Artiushin, Gregory A Jicha, Wang-Xia Wang, Erin L Abner, Andrew J Saykin, Walter A Kukull, David W Fard. Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging. Acta neuropathologica. vol 132. issue 6. 2017-09-20. PMID:27815632. we found that the rs73069071 risk genotype was associated with hippocampal sclerosis (hs) pathology among people with the rs704180 risk genotype (national alzheimer's coordinating center/alzheimer's disease genetic consortium data; n = 2113, including 241 autopsy-confirmed hs cases). 2017-09-20 2023-08-13 human
Helen Ling, Huw R Morris, James W Neal, Andrew J Lees, John Hardy, Janice L Holton, Tamas Revesz, David D R William. Mixed pathologies including chronic traumatic encephalopathy account for dementia in retired association football (soccer) players. Acta neuropathologica. vol 133. issue 3. 2017-09-20. PMID:28205009. four cases had pathologically confirmed cte; concomitant pathologies included alzheimer's disease (n = 6), tdp-43 (n = 6), cerebral amyloid angiopathy (n = 5), hippocampal sclerosis (n = 2), corticobasal degeneration (n = 1), dementia with lewy bodies (n = 1), and vascular pathology (n = 1); and all would have contributed synergistically to the clinical manifestations. 2017-09-20 2023-08-13 human
Stephen W Scheff, Mubeen A Ansari, Elliott J Mufso. Oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with Alzheimer's disease pathology. Neurobiology of aging. vol 42. 2017-09-19. PMID:27143416. oxidative stress and hippocampal synaptic protein levels in elderly cognitively intact individuals with alzheimer's disease pathology. 2017-09-19 2023-08-13 human
Jason Hassenstab, Rachel Chasse, Perri Grabow, Tammie L S Benzinger, Anne M Fagan, Chengjie Xiong, Mateusz Jasielec, Elizabeth Grant, John C Morri. Certified normal: Alzheimer's disease biomarkers and normative estimates of cognitive functioning. Neurobiology of aging. vol 43. 2017-09-19. PMID:27255812. a total of 264 cognitively normal (clinical dementia rating = 0) older adults were classified as biomarker negative ("robust normal," n = 177) or biomarker positive ("preclinical alzheimer's disease" [pcad], n = 87) based on amyloid imaging, cerebrospinal fluid biomarkers, and hippocampal volumes. 2017-09-19 2023-08-13 human
Paula Abeijon, Xerardo Garcia-Mera, Olga Caamano, Matilde Yanez, Edgar Lopez-Castro, Francisco J Romero-Duran, Humberto Gonzalez-Dia. Multi-Target Mining of Alzheimer Disease Proteome with Hansch's QSBR-Perturbation Theory and Experimental-Theoretic Study of New Thiophene Isosters of Rasagiline. Current drug targets. vol 18. issue 5. 2017-09-13. PMID:26521774. the targets are proteins expressed by the hippocampus region of the brain of alzheimer disease (ad) patients. 2017-09-13 2023-08-13 Not clear
Xike Qin, Yunling Wang, Hemant K Paude. Inhibition of Early Growth Response 1 in the Hippocampus Alleviates Neuropathology and Improves Cognition in an Alzheimer Model with Plaques and Tangles. The American journal of pathology. vol 187. issue 8. 2017-09-12. PMID:28641077. inhibition of early growth response 1 in the hippocampus alleviates neuropathology and improves cognition in an alzheimer model with plaques and tangles. 2017-09-12 2023-08-13 mouse
Hancan Zhu, Hewei Cheng, Xuesong Yang, Yong Fa. Metric Learning for Multi-atlas based Segmentation of Hippocampus. Neuroinformatics. vol 15. issue 1. 2017-09-11. PMID:27638650. automatic and reliable segmentation of hippocampus from mr brain images is of great importance in studies of neurological diseases, such as epilepsy and alzheimer's disease. 2017-09-11 2023-08-13 human
Xiaoliang Jiang, Zhaozhong Zhou, Xiaokang Ding, Xiaolei Deng, Ling Zou, Bailin L. Level Set Based Hippocampus Segmentation in MR Images with Improved Initialization Using Region Growing. Computational and mathematical methods in medicine. vol 2017. 2017-09-07. PMID:28191031. the hippocampus has been known as one of the most important structures referred to as alzheimer's disease and other neurological disorders. 2017-09-07 2023-08-13 Not clear
I-Seul Joe, Jong-Hwan Kim, Hanna Kim, Jung-Hwa Hong, Mirang Kim, Mikyoung Par. Cyclin Y-mediated transcript profiling reveals several important functional pathways regulated by Cyclin Y in hippocampal neurons. PloS one. vol 12. issue 2. 2017-09-07. PMID:28241067. in addition, the mrna levels of some genes enriched for those annotation terms and pathways or genes reported to be altered in alzheimer's disease mouse model were further validated by quantitative real-time pcr in hippocampal neuronal cells. 2017-09-07 2023-08-13 mouse
Andreas Schrötter, Andrea Oberhaus, Katharina Kolbe, Svenja Seger, Thomas Mastalski, Fouzi El Magraoui, Edeltraut Hoffmann-Posorske, Michael Bohnert, Jürgen Deckert, Christian Braun, Matthias Graw, Christoph Schmitz, Thomas Arzberger, Christina Loosse, Helmut Heinsen, Helmut E Meyer, Thorsten Mülle. LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease. Biochimica et biophysica acta. Proteins and proteomics. vol 1865. issue 6. 2017-09-07. PMID:28377147. lmd proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to alzheimer's disease. 2017-09-07 2023-08-13 human
Andreas Schrötter, Andrea Oberhaus, Katharina Kolbe, Svenja Seger, Thomas Mastalski, Fouzi El Magraoui, Edeltraut Hoffmann-Posorske, Michael Bohnert, Jürgen Deckert, Christian Braun, Matthias Graw, Christoph Schmitz, Thomas Arzberger, Christina Loosse, Helmut Heinsen, Helmut E Meyer, Thorsten Mülle. LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease. Biochimica et biophysica acta. Proteins and proteomics. vol 1865. issue 6. 2017-09-07. PMID:28377147. human hippocampal area cornu ammonis (ca) 1 is one of the first fields in the human telencephalon showing alzheimer disease (ad)-specific neuropathological changes. 2017-09-07 2023-08-13 human
Rosaliana Libro, Placido Bramanti, Emanuela Mazzo. Endogenous glucocorticoids: role in the etiopathogenesis of Alzheimer's disease. Neuro endocrinology letters. vol 38. issue 1. 2017-08-29. PMID:28456142. however, enhanced basal egcs levels have been observed in patients affected by alzheimer's disease (ad) and they have been correlated with dysregulation of the hypothalamic-pituitary-adrenocortical axis, hippocampal degeneration and reduced cognitive/memory performance. 2017-08-29 2023-08-13 Not clear