All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Christy M Kelley, Jessica A Ash, Brian E Powers, Ramon Velazquez, Melissa J Alldred, Milos D Ikonomovic, Stephen D Ginsberg, Barbara J Strupp, Elliott J Mufso. Effects of Maternal Choline Supplementation on the Septohippocampal Cholinergic System in the Ts65Dn Mouse Model of Down Syndrome. Current Alzheimer research. vol 13. issue 1. 2016-09-19. PMID:26391045. down syndrome (ds), caused by trisomy of chromosome 21, is marked by intellectual disability (id) and early onset of alzheimer's disease (ad) neuropathology including hippocampal cholinergic projection system degeneration. 2016-09-19 2023-08-13 mouse
Johannes Schröder, Johannes Pante. Neuroimaging of hippocampal atrophy in early recognition of Alzheimer's disease--a critical appraisal after two decades of research. Psychiatry research. Neuroimaging. vol 247. 2016-09-16. PMID:26774855. neuroimaging of hippocampal atrophy in early recognition of alzheimer's disease--a critical appraisal after two decades of research. 2016-09-16 2023-08-13 human
Johannes Schröder, Johannes Pante. Neuroimaging of hippocampal atrophy in early recognition of Alzheimer's disease--a critical appraisal after two decades of research. Psychiatry research. Neuroimaging. vol 247. 2016-09-16. PMID:26774855. as a characteristic feature of alzheimer's disease (ad) hippocampal atrophy (ha) can be demonstrated in the majority of patients by using neuroimaging techniques in particular magnetic resonance imaging (mri). 2016-09-16 2023-08-13 human
Yan Wang, Biao Cai, Jing Shao, Ting-Ting Wang, Run-Ze Cai, Chang-Ju Ma, Tao Han, Jun D. Genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with Alzheimer's disease. Neural regeneration research. vol 11. issue 7. 2016-09-16. PMID:27630702. genistein suppresses the mitochondrial apoptotic pathway in hippocampal neurons in rats with alzheimer's disease. 2016-09-16 2023-08-13 rat
Mario Díaz, Noemí Fabelo, Verónica Casañas-Sánchez, Raquel Marin, Tomás Gómez, David Quinto-Alemany, José A Pére. Hippocampal Lipid Homeostasis in APP/PS1 Mice is Modulated by a Complex Interplay Between Dietary DHA and Estrogens: Relevance for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 49. issue 2. 2016-09-12. PMID:26519437. hippocampal lipid homeostasis in app/ps1 mice is modulated by a complex interplay between dietary dha and estrogens: relevance for alzheimer's disease. 2016-09-12 2023-08-13 mouse
Mario Díaz, Noemí Fabelo, Verónica Casañas-Sánchez, Raquel Marin, Tomás Gómez, David Quinto-Alemany, José A Pére. Hippocampal Lipid Homeostasis in APP/PS1 Mice is Modulated by a Complex Interplay Between Dietary DHA and Estrogens: Relevance for Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 49. issue 2. 2016-09-12. PMID:26519437. current evidence suggests that lipid homeostasis in the hippocampus is affected by different genetic, dietary, and hormonal factors, and that its deregulation may be associated with the onset and progression of alzheimer's disease (ad). 2016-09-12 2023-08-13 mouse
Shutaro Katsurabayashi, Hiroyuki Kawano, Miyuki Ii, Sachiko Nakano, Chihiro Tatsumi, Kaori Kubota, Kotaro Takasaki, Kenichi Mishima, Michihiro Fujiwara, Katsunori Iwasak. Overexpression of Swedish mutant APP in aged astrocytes attenuates excitatory synaptic transmission. Physiological reports. vol 4. issue 1. 2016-09-12. PMID:26733247. in this study, the effect of astrocytic overexpression of a mutant app on the excitatory synaptic transmission was investigated using coculture system of the transgenic (tg) cortical astrocytes that express the human app695 polypeptide with the double mutation k670n + m671l found in a large swedish family with early onset alzheimer's disease, and wild-type hippocampal neuron. 2016-09-12 2023-08-13 mouse
Krzysztof Sendrowski, Wojciech Sobaniec, Anna Stasiak-Barmuta, Piotr Sobaniec, Janusz Popk. Study of the protective effects of nootropic agents against neuronal damage induced by amyloid-beta (fragment 25-35) in cultured hippocampal neurons. Pharmacological reports : PR. vol 67. issue 2. 2016-09-06. PMID:25712658. alzheimer's disease (ad) is a common neurodegenerative disorder, in which progressive neuron loss, mainly in the hippocampus, is observed. 2016-09-06 2023-08-13 Not clear
Christiane S H Oedekoven, Andreas Jansen, James L Keidel, Tilo Kircher, Dirk Leub. The influence of age and mild cognitive impairment on associative memory performance and underlying brain networks. Brain imaging and behavior. vol 9. issue 4. 2016-09-02. PMID:25381653. the most important neural substrate of associative memory is the hippocampus, a structure crucially implicated in the pathogenesis of alzheimer's disease (ad). 2016-09-02 2023-08-13 Not clear
Tzu-Wei Lin, Yu-Fan Liu, Yao-Hsiang Shih, Shean-Jen Chen, Tung-Yi Huang, Chia-Yuan Chang, Chi-Hsiang Lien, Lung Yu, Shun-Hua Chen, Yu-Min Ku. Neurodegeneration in Amygdala Precedes Hippocampus in the APPswe/ PS1dE9 Mouse Model of Alzheimer's Disease. Current Alzheimer research. vol 12. issue 10. 2016-08-26. PMID:26502818. neurodegeneration in amygdala precedes hippocampus in the appswe/ ps1de9 mouse model of alzheimer's disease. 2016-08-26 2023-08-13 mouse
Tzu-Wei Lin, Yu-Fan Liu, Yao-Hsiang Shih, Shean-Jen Chen, Tung-Yi Huang, Chia-Yuan Chang, Chi-Hsiang Lien, Lung Yu, Shun-Hua Chen, Yu-Min Ku. Neurodegeneration in Amygdala Precedes Hippocampus in the APPswe/ PS1dE9 Mouse Model of Alzheimer's Disease. Current Alzheimer research. vol 12. issue 10. 2016-08-26. PMID:26502818. both the hippocampus and amygdala are early vulnerable brain regions in the development of alzheimer's disease (ad). 2016-08-26 2023-08-13 mouse
Lucas Rasmussen, Roger W de Labio, Gustavo A Viani, Elizabeth Chen, Joao Villares, Paulo-Henrique Bertolucci, Thais S Minett, Gustavo Turecki, Danielle Cecyre, Sandra A Drigo, Marilia C Smith, Spencer L M Paya. Differential Expression of Ribosomal Genes in Brain and Blood of Alzheimer's Disease Patients. Current Alzheimer research. vol 12. issue 10. 2016-08-26. PMID:26502820. in this study, we investigated the mrna expression of ribosomal genes (28s/18s) and β-amyloid precursor protein (app) in different post mortem brain tissue regions (the entorhinal and auditory cortices and the hippocampus) of ad patients and elderly control subjects and also evaluated the extent of expression in peripheral blood from young, healthy, elderly, and alzheimer's disease patients in order to investigate whether these individuals experienced the effects of aging. 2016-08-26 2023-08-13 human
E Herran, R Perez-Gonzalez, M Igartua, J L Pedraz, E Carro, R M Hernande. Enhanced Hippocampal Neurogenesis in APP/Ps1 Mouse Model of Alzheimer's Disease After Implantation of VEGF-loaded PLGA Nanospheres. Current Alzheimer research. vol 12. issue 10. 2016-08-26. PMID:26502822. enhanced hippocampal neurogenesis in app/ps1 mouse model of alzheimer's disease after implantation of vegf-loaded plga nanospheres. 2016-08-26 2023-08-13 mouse
Yueping Peng, Jue Wang, Chongxun Zhen. Study on dynamic characteristics' change of hippocampal neuron reduced models caused by the Alzheimer's disease. Journal of biological dynamics. vol 10. 2016-08-26. PMID:26998957. study on dynamic characteristics' change of hippocampal neuron reduced models caused by the alzheimer's disease. 2016-08-26 2023-08-13 Not clear
Yueping Peng, Jue Wang, Chongxun Zhen. Study on dynamic characteristics' change of hippocampal neuron reduced models caused by the Alzheimer's disease. Journal of biological dynamics. vol 10. 2016-08-26. PMID:26998957. in the paper, based on the electrophysiological experimental data, the hippocampal neuron reduced model under the pathology condition of alzheimer's disease (ad) has been built by modifying parameters' values. 2016-08-26 2023-08-13 Not clear
Bolun Li, Jie Shi, Boris A Gutman, Leslie C Baxter, Paul M Thompson, Richard J Caselli, Yalin Wan. Influence of APOE Genotype on Hippocampal Atrophy over Time - An N=1925 Surface-Based ADNI Study. PloS one. vol 11. issue 4. 2016-08-25. PMID:27065111. in the alzheimer's disease neuroimaging initiative (adni) cohort, we previously reported significant baseline structural differences in apoe e4 carriers relative to non-carriers, involving the left hippocampus more than the right--a difference more pronounced in e4 homozygotes than heterozygotes. 2016-08-25 2023-08-13 human
Marie Violet, Alban Chauderlier, Lucie Delattre, Meryem Tardivel, Meliza Sendid Chouala, Audrey Sultan, Elodie Marciniak, Sandrine Humez, Lester Binder, Rakez Kayed, Bruno Lefebvre, Eliette Bonnefoy, Luc Buée, Marie-Christine Gala. Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo. Neurobiology of disease. vol 82. 2016-08-24. PMID:26385829. the accumulation of dna and rna oxidative damage is observed in cortical and hippocampal neurons from alzheimer's disease (ad) brains at early stages of pathology. 2016-08-24 2023-08-13 mouse
Aránzazu Perianes-Cachero, Sandra Canelles, David Aguado-Llera, Laura M Frago, María Val Toledo-Lobo, Iván Carrera, Ramón Cacabelos, Julie A Chowen, Jesús Argente, Eduardo Arilla-Ferreiro, Vicente Barrio. Reduction in Aβ-induced cell death in the hippocampus of 17β-estradiol-treated female rats is associated with an increase in IGF-I signaling and somatostatinergic tone. Journal of neurochemistry. vol 135. issue 6. 2016-08-22. PMID:26442993. as alterations in somatostatin have been demonstrated in alzheimer's disease, we examined whether e2 prevents changes in the hippocampal somatostatinergic system induced by aβ25-35 and cell death, as well as the possible involvement of leptin and insulin-like growth factor (igf)-i signaling. 2016-08-22 2023-08-13 rat
M Dolores Muñoz, Mónica Antolín-Vallespín, Silvia Tapia-González, Amelia Sánchez-Capel. Smad3 deficiency inhibits dentate gyrus LTP by enhancing GABAA neurotransmission. Journal of neurochemistry. vol 137. issue 2. 2016-08-22. PMID:26826552. alteration of gaba neurotransmission is thought to produce hippocampal cognitive dysfunction in down's syndrome or alzheimer's disease, and here we provide new insights into the hippocampal changes in an animal model of parkinson's disease. 2016-08-22 2023-08-13 mouse
Naftali Raz, Ana M Daugherty, Andrew R Bender, Cheryl L Dahle, Susan Lan. Volume of the hippocampal subfields in healthy adults: differential associations with age and a pro-inflammatory genetic variant. Brain structure & function. vol 220. issue 5. 2016-08-19. PMID:24947882. we examined the associations of hippocampal subfield volumes with age, a vascular risk factor (hypertension), and genetic polymorphisms associated with variation in pro-inflammatory cytokines levels (il-1β c-511t and il-6 c-174g) and risk for alzheimer's disease (apoeε4) in healthy adult volunteers (n = 80; age = 22-82 years). 2016-08-19 2023-08-13 human