| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Weihao Tang, Joshua H K Tam, Claudia Seah, Justin Chiu, Andrea Tyrer, Sean P Cregan, Susan O Meakin, Stephen H Pasterna. Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes. Molecular brain. vol 8. 2016-04-07. PMID:26170135. |
arf6 expression increases through the hippocampus with the development of alzheimer's disease, being expressed mostly in the ca1 and ca2 regions in normal individuals but spreading through the ca3 and ca4 regions in individuals with pathologically diagnosed ad. |
2016-04-07 |
2023-08-13 |
Not clear |
| Shashi Kant Tiwari, Brashket Seth, Swati Agarwal, Anuradha Yadav, Madhumita Karmakar, Shailendra Kumar Gupta, Vinay Choubey, Abhay Sharma, Rajnish Kumar Chaturved. Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. The Journal of biological chemistry. vol 290. issue 47. 2016-03-27. PMID:26420483. |
ethosuximide induces hippocampal neurogenesis and reverses cognitive deficits in an amyloid-β toxin-induced alzheimer rat model via the phosphatidylinositol 3-kinase (pi3k)/akt/wnt/β-catenin pathway. |
2016-03-27 |
2023-08-13 |
rat |
| Shashi Kant Tiwari, Brashket Seth, Swati Agarwal, Anuradha Yadav, Madhumita Karmakar, Shailendra Kumar Gupta, Vinay Choubey, Abhay Sharma, Rajnish Kumar Chaturved. Ethosuximide Induces Hippocampal Neurogenesis and Reverses Cognitive Deficits in an Amyloid-β Toxin-induced Alzheimer Rat Model via the Phosphatidylinositol 3-Kinase (PI3K)/Akt/Wnt/β-Catenin Pathway. The Journal of biological chemistry. vol 290. issue 47. 2016-03-27. PMID:26420483. |
adult hippocampal neurogenesis is involved in cognitive functions and altered in various neurodegenerative disorders, including alzheimer disease (ad). |
2016-03-27 |
2023-08-13 |
rat |
| Wen Li, Huan Liu, Min Yu, Xumei Zhang, Meilin Zhang, John X Wilson, Guowei Huan. Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice. The Journal of nutritional biochemistry. vol 26. issue 8. 2016-03-25. PMID:25959374. |
alzheimer's disease (ad) is associated with malnutrition, altered one-carbon metabolism and increased hippocampal amyloid-β peptide (aβ) accumulation. |
2016-03-25 |
2023-08-13 |
mouse |
| Karla Salgado-Puga, Roberto A Prado-Alcalá, Fernando Peña-Orteg. Amyloid β Enhances Typical Rodent Behavior While It Impairs Contextual Memory Consolidation. Behavioural neurology. vol 2015. 2016-03-25. PMID:26229236. |
alzheimer's disease (ad) is associated with an early hippocampal dysfunction, which is likely induced by an increase in soluble amyloid beta peptide (aβ). |
2016-03-25 |
2023-08-13 |
mouse |
| L Zhang, X Q Guo, J F Chu, X Zhang, Z R Yan, Y Z L. Potential hippocampal genes and pathways involved in Alzheimer's disease: a bioinformatic analysis. Genetics and molecular research : GMR. vol 14. issue 2. 2016-03-24. PMID:26125932. |
potential hippocampal genes and pathways involved in alzheimer's disease: a bioinformatic analysis. |
2016-03-24 |
2023-08-13 |
Not clear |
| Stefan J Teipel, Michel J Grothe, Katharina Wittfeld, Wolfgang Hoffmann, Katrin Hegenscheid, Henry Völzke, Georg Homuth, Hans J Grab. Association of a neurokinin 3 receptor polymorphism with the anterior basal forebrain. Neurobiology of aging. vol 36. issue 6. 2016-03-17. PMID:25976010. |
in alzheimer's disease, the rs2765 single-nucleotide polymorphism (snp) of the nk3 receptor-coding gene tacr3 was correlated with the right hippocampus volume. |
2016-03-17 |
2023-08-13 |
human |
| Jana Mrzílkova, Antonella Koutela, Martina Kutová, Matěj Patzelt, Ibrahim Ibrahim, Dina Al-Kayssi, Aleš Bartoš, Daniela Řípová, Pavla Čermáková, Petr Zac. Hippocampal spatial position evaluation on MRI for research and clinical practice. PloS one. vol 9. issue 12. 2016-03-09. PMID:25502906. |
in order to find out whether it has an overall effect on the resulting 2d data, manual hippocampal area measurements and rotation variability of the brain (in two reoriented axes) and the skull were performed in 23 alzheimer's disease patients and 31 healthy controls. |
2016-03-09 |
2023-08-13 |
Not clear |
| Karel J Bemelmans, Annemarie Noort, Roel de Rijk, Huub A M Middelkoop, Godfried M J van Kempen, Jaap G Goekoo. Plasma cortisol and norepinephrine in Alzheimer's disease: opposite relations with recall performance and stage of progression. Acta neuropsychiatrica. vol 19. issue 4. 2016-03-09. PMID:26952889. |
alzheimer's disease (ad) is characterized by effortful retrieval memory impairments, loss of hippocampal neurons and elevated plasma cortisol (cort) concentrations. |
2016-03-09 |
2023-08-13 |
Not clear |
| Jiang Cheng, Zhi-Wei Zhou, Hui-Ping Sheng, Lan-Jie He, Xue-Wen Fan, Zhi-Xu He, Tao Sun, Xueji Zhang, Ruan Jin Zhao, Ling Gu, Chuanhai Cao, Shu-Feng Zho. An evidence-based update on the pharmacological activities and possible molecular targets of Lycium barbarum polysaccharides. Drug design, development and therapy. vol 9. 2016-03-08. PMID:25552899. |
lbps ameliorate the symptoms of mice with alzheimer's disease and enhance neurogenesis in the hippocampus and subventricular zone, improving learning and memory abilities. |
2016-03-08 |
2023-08-13 |
mouse |
| Laura E M Wisse, Yael D Reijmer, Annemieke ter Telgte, Hugo J Kuijf, Alexander Leemans, Peter R Luijten, Huiberdina L Koek, Mirjam I Geerlings, Geert Jan Biessel. Hippocampal disconnection in early Alzheimer's disease: a 7 tesla MRI study. Journal of Alzheimer's disease : JAD. vol 45. issue 4. 2016-03-08. PMID:25697703. |
hippocampal disconnection in early alzheimer's disease: a 7 tesla mri study. |
2016-03-08 |
2023-08-13 |
Not clear |
| Se Hee Oh, Ha Na Kim, Hyun-Jung Park, Jin Young Shin, Phil Hyu Le. Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model. Cell transplantation. vol 24. issue 6. 2016-03-07. PMID:24612635. |
mesenchymal stem cells increase hippocampal neurogenesis and neuronal differentiation by enhancing the wnt signaling pathway in an alzheimer's disease model. |
2016-03-07 |
2023-08-12 |
Not clear |
| Se Hee Oh, Ha Na Kim, Hyun-Jung Park, Jin Young Shin, Phil Hyu Le. Mesenchymal Stem Cells Increase Hippocampal Neurogenesis and Neuronal Differentiation by Enhancing the Wnt Signaling Pathway in an Alzheimer's Disease Model. Cell transplantation. vol 24. issue 6. 2016-03-07. PMID:24612635. |
neurogenesis in the subgranular zone of the hippocampal dentate gyrus may act as an endogenous repair mechanism in alzheimer's disease (ad), and the wnt signaling pathway has been suggested to closely modulate neurogenesis in amyloid-β (aβ)-related ad models. |
2016-03-07 |
2023-08-12 |
Not clear |
| Xiao Liu, Hongyan Zuo, Dewen Wang, Ruiyun Peng, Tao Song, Shuiming Wang, Xinping Xu, Yabing Gao, Yang Li, Shaoxia Wang, Lifeng Wang, Li Zha. Improvement of spatial memory disorder and hippocampal damage by exposure to electromagnetic fields in an Alzheimer's disease rat model. PloS one. vol 10. issue 5. 2016-03-04. PMID:25978363. |
improvement of spatial memory disorder and hippocampal damage by exposure to electromagnetic fields in an alzheimer's disease rat model. |
2016-03-04 |
2023-08-13 |
rat |
| Candida Dias, Rui M Barbosa, Joao Laranjinha, Ana Led. Evaluation of Mitochondrial Function in the CNS of Rodent Models of Alzheimer's Disease - High Resolution Respirometry Applied to Acute Hippocampal Slices. Free radical biology & medicine. vol 75 Suppl 1. 2016-03-01. PMID:26461355. |
evaluation of mitochondrial function in the cns of rodent models of alzheimer's disease - high resolution respirometry applied to acute hippocampal slices. |
2016-03-01 |
2023-08-13 |
mouse |
| Vasily Vorobyov, Vladimir Kaptsov, Rita Gordon, Ekaterina Makarova, Igor Podolski, Frank Sengpie. Neuroprotective effects of hydrated fullerene C60: cortical and hippocampal EEG interplay in an amyloid-infused rat model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 45. issue 1. 2016-02-29. PMID:25589720. |
neuroprotective effects of hydrated fullerene c60: cortical and hippocampal eeg interplay in an amyloid-infused rat model of alzheimer's disease. |
2016-02-29 |
2023-08-13 |
rat |
| Vasily Vorobyov, Vladimir Kaptsov, Rita Gordon, Ekaterina Makarova, Igor Podolski, Frank Sengpie. Neuroprotective effects of hydrated fullerene C60: cortical and hippocampal EEG interplay in an amyloid-infused rat model of Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 45. issue 1. 2016-02-29. PMID:25589720. |
we studied the effects of fullerene c60 nanoparticles, namely hydrated fullerene c60 (c60hyfn), on interrelations between eeg frequency spectra from the frontal cortex and the dorsal hippocampus (ca1) on an amyloid-β (aβ) rat model of alzheimer's disease (ad). |
2016-02-29 |
2023-08-13 |
rat |
| Juan Eugenio Iglesias, Jean C Augustinack, Khoa Nguyen, Christopher M Player, Allison Player, Michelle Wright, Nicole Roy, Matthew P Frosch, Ann C McKee, Lawrence L Wald, Bruce Fischl, Koen Van Leempu. A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI. NeuroImage. vol 115. 2016-02-29. PMID:25936807. |
the results show that the atlas and companion segmentation method: 1) can segment t1 and t2 images, as well as their combination, 2) replicate findings on mild cognitive impairment based on high-resolution t2 data, and 3) can discriminate between alzheimer's disease subjects and elderly controls with 88% accuracy in standard resolution (1mm) t1 data, significantly outperforming the atlas in freesurfer version 5.3 (86% accuracy) and classification based on whole hippocampal volume (82% accuracy). |
2016-02-29 |
2023-08-13 |
human |
| M Lorenzi, N Ayache, X Penne. Regional flux analysis for discovering and quantifying anatomical changes: An application to the brain morphometry in Alzheimer's disease. NeuroImage. vol 115. 2016-02-29. PMID:25963734. |
our experiments on the large cohorts of the adni dataset show that the regional flux analysis is a powerful and flexible instrument for the study of alzheimer's disease in a wide range of scenarios: cross-sectional deformation based morphometry, longitudinal discovery and quantification of group-wise volume changes, and statistically powered and robust quantification of hippocampal and ventricular atrophy. |
2016-02-29 |
2023-08-13 |
Not clear |
| I Pedrós, D Petrov, G Artiach, S Abad, C Ramon-Duaso, F Sureda, M Pallàs, C Beas-Zarate, J Folch, A Camin. Adipokine pathways are altered in hippocampus of an experimental mouse model of Alzheimer's disease. The journal of nutrition, health & aging. vol 19. issue 4. 2016-02-26. PMID:25809804. |
adipokine pathways are altered in hippocampus of an experimental mouse model of alzheimer's disease. |
2016-02-26 |
2023-08-13 |
mouse |