All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
George K Acquaah-Mensah, Nnenna Agu, Tayyiba Khan, Alice Gardne. A regulatory role for the insulin- and BDNF-linked RORA in the hippocampus: implications for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 3. 2015-10-26. PMID:25362032. a regulatory role for the insulin- and bdnf-linked rora in the hippocampus: implications for alzheimer's disease. 2015-10-26 2023-08-13 mouse
Todd E Morgan, Caleb E Finc. Astrocytic estrogen receptors and impaired neurotrophic responses in a rat model of perimenopause. Frontiers in aging neuroscience. vol 7. 2015-10-20. PMID:26483679. these findings are relevant to impairments of spatial learning and of hippocampal long-term potentiation during the onset of ir in middle-aged rats, and to perimenopausal factors mediating the higher risk of women for alzheimer disease. 2015-10-20 2023-08-13 rat
Joy L Taylor, Blake K Scanlon, Michelle Farrell, Beatriz Hernandez, Maheen M Adamson, J Wesson Ashford, Art Noda, Greer M Murphy, Michael W Weine. APOE-epsilon4 and aging of medial temporal lobe gray matter in healthy adults older than 50 years. Neurobiology of aging. vol 35. issue 11. 2015-10-19. PMID:24929969. atrophy of the hippocampus and surrounding temporal regions occurs in alzheimer's disease (ad). 2015-10-19 2023-08-13 Not clear
Robert Alan Mans, Brian A Warmus, Caroline C Smith, Lori L McMaho. An acetylcholinesterase inhibitor, eserine, induces long-term depression at CA3-CA1 synapses in the hippocampus of adult rats. Journal of neurophysiology. vol 112. issue 10. 2015-10-19. PMID:25143547. acetylcholinesterase (ache) inhibitors are commonly prescribed to enhance cholinergic signaling in alzheimer's disease in hopes of rescuing cognitive function, caused, in part, by degeneration of cholinergic innervation to the hippocampus and cortex. 2015-10-19 2023-08-13 rat
John C Gant, Kuey-Chu Chen, Inga Kadish, Eric M Blalock, Olivier Thibault, Nada M Porter, Philip W Landfiel. Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 30. 2015-10-16. PMID:26224869. previously, we found that expression of the gene encoding fk506-binding protein 12.6/1b (fkbp1b), a small immunophilin that stabilizes ryr-mediated ca2+ release in cardiomyocytes, declines in hippocampus of aged rats and alzheimer's disease subjects. 2015-10-16 2023-08-13 human
Ingrid Heggland, Inge S Storkaas, Hanne T Soligard, Asgeir Kobro-Flatmoen, Menno P Witte. Stereological estimation of neuron number and plaque load in the hippocampal region of a transgenic rat model of Alzheimer's disease. The European journal of neuroscience. vol 41. issue 9. 2015-10-12. PMID:25808554. stereological estimation of neuron number and plaque load in the hippocampal region of a transgenic rat model of alzheimer's disease. 2015-10-12 2023-08-13 human
András Szark. [THE ROLE OF β-AMYLOID AND MITOCHONDRIAL DYSFUNCTION IN THE PATHOGENESIS OF ALZHEIMER'S DISEASE]. Ideggyogyaszati szemle. vol 68. issue 7-8. 2015-10-09. PMID:26380416. three predominant neuropathologic features of the brain in alzheimer disease are: the intracellular neurofibrillary tangles consisting mainly of the hyperphosphorylated protein τ; the extracellular amyloid deposits (neuritic plaques) consisting of amyloid β peptide; and the extensive neuronal cell loss in the hippocampus and in portions of the cerebral cortex. 2015-10-09 2023-08-13 Not clear
Florent L Besson, Renaud La Joie, Loïc Doeuvre, Malo Gaubert, Florence Mézenge, Stéphanie Egret, Brigitte Landeau, Louisa Barré, Ahmed Abbas, Meziane Ibazizene, Vincent de La Sayette, Béatrice Desgranges, Francis Eustache, Gaël Chétela. Cognitive and Brain Profiles Associated with Current Neuroimaging Biomarkers of Preclinical Alzheimer's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 29. 2015-10-07. PMID:26203136. neuroimaging biomarkers, namely hippocampal volume loss, temporoparietal hypometabolism, and neocortical β-amyloid (aβ) deposition, are included in the recent research criteria for preclinical alzheimer's disease (ad). 2015-10-07 2023-08-13 Not clear
Michael J Stuart, Gaurav Singhal, Bernhard T Baun. Systematic Review of the Neurobiological Relevance of Chemokines to Psychiatric Disorders. Frontiers in cellular neuroscience. vol 9. 2015-10-07. PMID:26441528. notable exceptions include ccl11 that has recently been shown to impair hippocampal function in aging - of distinct relevance to alzheimer's disease and depression in the elderly, and pre-natal exposure to cxcl8 that may disrupt early neurodevelopmental periods predisposing to schizophrenia. 2015-10-07 2023-08-13 human
Erika Calvo-Ochoa, Clorinda Aria. Cellular and metabolic alterations in the hippocampus caused by insulin signalling dysfunction and its association with cognitive impairment during aging and Alzheimer's disease: studies in animal models. Diabetes/metabolism research and reviews. vol 31. issue 1. 2015-10-01. PMID:24464982. cellular and metabolic alterations in the hippocampus caused by insulin signalling dysfunction and its association with cognitive impairment during aging and alzheimer's disease: studies in animal models. 2015-10-01 2023-08-12 Not clear
Florence Rémy, Nathalie Vayssière, Laure Saint-Aubert, Emmanuel Barbeau, Jérémie Parient. White matter disruption at the prodromal stage of Alzheimer's disease: relationships with hippocampal atrophy and episodic memory performance. NeuroImage. Clinical. vol 7. 2015-09-24. PMID:25685715. white matter disruption at the prodromal stage of alzheimer's disease: relationships with hippocampal atrophy and episodic memory performance. 2015-09-24 2023-08-13 human
Alessandro Tozzi, Alessandra Sclip, Michela Tantucci, Antonio de Iure, Veronica Ghiglieri, Cinzia Costa, Massimiliano Di Filippo, Tiziana Borsello, Paolo Calabres. Region- and age-dependent reductions of hippocampal long-term potentiation and NMDA to AMPA ratio in a genetic model of Alzheimer's disease. Neurobiology of aging. vol 36. issue 1. 2015-09-21. PMID:25104560. region- and age-dependent reductions of hippocampal long-term potentiation and nmda to ampa ratio in a genetic model of alzheimer's disease. 2015-09-21 2023-08-13 mouse
Alessandro Tozzi, Alessandra Sclip, Michela Tantucci, Antonio de Iure, Veronica Ghiglieri, Cinzia Costa, Massimiliano Di Filippo, Tiziana Borsello, Paolo Calabres. Region- and age-dependent reductions of hippocampal long-term potentiation and NMDA to AMPA ratio in a genetic model of Alzheimer's disease. Neurobiology of aging. vol 36. issue 1. 2015-09-21. PMID:25104560. to characterize the mechanisms underlying region- and age-dependent hippocampal synaptic dysfunction in alzheimer's disease, we used transgenic crnd8 mice, expressing the swedish-indiana app mutation. 2015-09-21 2023-08-13 mouse
Xiaoying Tang, Dominic Holland, Anders M Dale, Laurent Younes, Michael I Mille. Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 2. 2015-09-21. PMID:25318546. this predictor is based on the shape diffeomorphometry patterns of subcortical and ventricular structures (left and right amygdala, hippocampus, thalamus, caudate, putamen, globus pallidus, and lateral ventricle) of 607 baseline scans from the alzheimer's disease neuroimaging initiative database, including a total of 210 healthy control subjects, 222 mci subjects, and 175 ad subjects. 2015-09-21 2023-08-13 human
Xiaoying Tang, Dominic Holland, Anders M Dale, Laurent Younes, Michael I Mille. Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 2. 2015-09-21. PMID:25318546. statistically significant correlation maps were observed between the shape diffeomorphometry features of each of the 14 structures, especially the bilateral amygdala, hippocampus, lateral ventricle, and two neuropsychological test scores--the alzheimer's disease assessment scale-cognitive behavior section and the mini-mental state examination. 2015-09-21 2023-08-13 human
Geon Ha Kim, Jae Hong Lee, Sang Won Seo, Jeong Hun Kim, Joon-Kyung Seong, Byoung Seok Ye, Hanna Cho, Young Noh, Hee Jin Kim, Cindy W Yoon, Seung Jun Oh, Jae Seung Kim, Yearn Seong Choe, Kyung Han Lee, Sung Tae Kim, Jung Won Hwang, Jee Hyang Jeong, Duk L N. Hippocampal volume and shape in pure subcortical vascular dementia. Neurobiology of aging. vol 36. issue 1. 2015-09-21. PMID:25444608. the purposes of the present study were to explore whether hippocampal atrophy exists in pure subcortical vascular dementia (svad) as defined by negative (11)c-pittsburg compound-b (pib(-)) positron emission tomography and to compare hippocampal volume and shape between pib(-) svad and pib positive (pib(+)) alzheimer's disease (ad) dementia. 2015-09-21 2023-08-13 Not clear
Henry Ka-Fung Mak, Wenshu Qian, Kwok Sing Ng, Queenie Chan, You-Qiang Song, Leung Wing Chu, Kelvin Kai-Wing Ya. Combination of MRI hippocampal volumetry and arterial spin labeling MR perfusion at 3-Tesla improves the efficacy in discriminating Alzheimer's disease from cognitively normal elderly adults. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24670395. combination of mri hippocampal volumetry and arterial spin labeling mr perfusion at 3-tesla improves the efficacy in discriminating alzheimer's disease from cognitively normal elderly adults. 2015-09-18 2023-08-12 Not clear
Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. increased hippocampal blood flow in sedentary older adults at genetic risk for alzheimer's disease. 2015-09-18 2023-08-12 Not clear
Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. resting cerebral blood flow (cbf) decreases with age; however regulatory increases in hippocampal cbf have been associated with genetic risk (apolipoprotein e [apoe] ε4 carriers) for alzheimer's disease (ad). 2015-09-18 2023-08-12 Not clear
Jiu Chen, Zhijun Zhang, Shijiang L. Can multi-modal neuroimaging evidence from hippocampus provide biomarkers for the progression of amnestic mild cognitive impairment? Neuroscience bulletin. vol 31. issue 1. 2015-09-18. PMID:25595368. impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment (amci) to alzheimer's disease (ad). 2015-09-18 2023-08-13 Not clear