| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoying Tang, Dominic Holland, Anders M Dale, Laurent Younes, Michael I Mille. Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 2. 2015-09-21. PMID:25318546. |
this predictor is based on the shape diffeomorphometry patterns of subcortical and ventricular structures (left and right amygdala, hippocampus, thalamus, caudate, putamen, globus pallidus, and lateral ventricle) of 607 baseline scans from the alzheimer's disease neuroimaging initiative database, including a total of 210 healthy control subjects, 222 mci subjects, and 175 ad subjects. |
2015-09-21 |
2023-08-13 |
human |
| Xiaoying Tang, Dominic Holland, Anders M Dale, Laurent Younes, Michael I Mille. Baseline shape diffeomorphometry patterns of subcortical and ventricular structures in predicting conversion of mild cognitive impairment to Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 44. issue 2. 2015-09-21. PMID:25318546. |
statistically significant correlation maps were observed between the shape diffeomorphometry features of each of the 14 structures, especially the bilateral amygdala, hippocampus, lateral ventricle, and two neuropsychological test scores--the alzheimer's disease assessment scale-cognitive behavior section and the mini-mental state examination. |
2015-09-21 |
2023-08-13 |
human |
| Geon Ha Kim, Jae Hong Lee, Sang Won Seo, Jeong Hun Kim, Joon-Kyung Seong, Byoung Seok Ye, Hanna Cho, Young Noh, Hee Jin Kim, Cindy W Yoon, Seung Jun Oh, Jae Seung Kim, Yearn Seong Choe, Kyung Han Lee, Sung Tae Kim, Jung Won Hwang, Jee Hyang Jeong, Duk L N. Hippocampal volume and shape in pure subcortical vascular dementia. Neurobiology of aging. vol 36. issue 1. 2015-09-21. PMID:25444608. |
the purposes of the present study were to explore whether hippocampal atrophy exists in pure subcortical vascular dementia (svad) as defined by negative (11)c-pittsburg compound-b (pib(-)) positron emission tomography and to compare hippocampal volume and shape between pib(-) svad and pib positive (pib(+)) alzheimer's disease (ad) dementia. |
2015-09-21 |
2023-08-13 |
Not clear |
| Henry Ka-Fung Mak, Wenshu Qian, Kwok Sing Ng, Queenie Chan, You-Qiang Song, Leung Wing Chu, Kelvin Kai-Wing Ya. Combination of MRI hippocampal volumetry and arterial spin labeling MR perfusion at 3-Tesla improves the efficacy in discriminating Alzheimer's disease from cognitively normal elderly adults. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24670395. |
combination of mri hippocampal volumetry and arterial spin labeling mr perfusion at 3-tesla improves the efficacy in discriminating alzheimer's disease from cognitively normal elderly adults. |
2015-09-18 |
2023-08-12 |
Not clear |
| Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. |
increased hippocampal blood flow in sedentary older adults at genetic risk for alzheimer's disease. |
2015-09-18 |
2023-08-12 |
Not clear |
| Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. |
resting cerebral blood flow (cbf) decreases with age; however regulatory increases in hippocampal cbf have been associated with genetic risk (apolipoprotein e [apoe] ε4 carriers) for alzheimer's disease (ad). |
2015-09-18 |
2023-08-12 |
Not clear |
| Jiu Chen, Zhijun Zhang, Shijiang L. Can multi-modal neuroimaging evidence from hippocampus provide biomarkers for the progression of amnestic mild cognitive impairment? Neuroscience bulletin. vol 31. issue 1. 2015-09-18. PMID:25595368. |
impaired structure and function of the hippocampus is a valuable predictor of progression from amnestic mild cognitive impairment (amci) to alzheimer's disease (ad). |
2015-09-18 |
2023-08-13 |
Not clear |
| Federico Scala, Salvatore Fusco, Cristian Ripoli, Roberto Piacentini, Domenica Donatella Li Puma, Matteo Spinelli, Fernanda Laezza, Claudio Grassi, Marcello D'Ascenz. Intraneuronal Aβ accumulation induces hippocampal neuron hyperexcitability through A-type K(+) current inhibition mediated by activation of caspases and GSK-3. Neurobiology of aging. vol 36. issue 2. 2015-09-17. PMID:25541422. |
in acute hippocampal slices derived from an adult triple-transgenic alzheimer's mouse model, characterized by endogenous intracellular accumulation of aβ42, ca1 pyramidal neurons exhibit hyperexcitability accompanied by increased phosphorylation of kv4.2 at ser-616. |
2015-09-17 |
2023-08-13 |
mouse |
| Robin de Flores, Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Florence Mézenge, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Effects of age and Alzheimer's disease on hippocampal subfields: comparison between manual and FreeSurfer volumetry. Human brain mapping. vol 36. issue 2. 2015-09-16. PMID:25231681. |
effects of age and alzheimer's disease on hippocampal subfields: comparison between manual and freesurfer volumetry. |
2015-09-16 |
2023-08-13 |
Not clear |
| Robin de Flores, Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Florence Mézenge, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Effects of age and Alzheimer's disease on hippocampal subfields: comparison between manual and FreeSurfer volumetry. Human brain mapping. vol 36. issue 2. 2015-09-16. PMID:25231681. |
hippocampal subfields were segmented in 133 individuals including 98 cognitively normal controls aged 19-84 years, 17 mild cognitive impairment and 18 alzheimer's disease (ad) patients using both methods. |
2015-09-16 |
2023-08-13 |
Not clear |
| Ya-min Liu, Zong-yang Li, Han Hu, Shu-ping Xu, Qi Chang, Yong-hong Liao, Rui-le Pan, Xin-min Li. Tenuifolin, a secondary saponin from hydrolysates of polygalasaponins, counteracts the neurotoxicity induced by Aβ25-35 peptides in vitro and in vivo. Pharmacology, biochemistry, and behavior. vol 128. 2015-09-16. PMID:25444865. |
alzheimer's disease (ad) is associated with damage to hippocampal neurons and declines in cognitive functions. |
2015-09-16 |
2023-08-13 |
mouse |
| F Clavaguera, J Hench, M Goedert, M Tolna. Invited review: Prion-like transmission and spreading of tau pathology. Neuropathology and applied neurobiology. vol 41. issue 1. 2015-09-15. PMID:25399729. |
in the most prevalent tauopathy, alzheimer's disease, tau pathology progresses in a stereotypical manner with the first lesions appearing in the locus coeruleus and the entorhinal cortex from where they appear to spread to the hippocampus and neocortex. |
2015-09-15 |
2023-08-13 |
Not clear |
| Tomoko Kato, Yoshihiro Konishi, Shun Shimohama, Thomas G Beach, Hiroyasu Akatsu, Ikuo Tooyam. Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients. Neuroscience letters. vol 591. 2015-09-15. PMID:25676811. |
in situ hybridization studies demonstrated that α1-chimaerin was expressed by neurons in the neo-cortex of the temporal lobe and the hippocampus of both controls and alzheimer's disease cases, with the signal intensity dramatically decreased in patients with alzheimer's disease. |
2015-09-15 |
2023-08-13 |
human |
| Yen Ying Lim, Robert H Pietrzak, Pierrick Bourgeat, David Ames, Kathryn A Ellis, Alan Rembach, Karra Harrington, Olivier Salvado, Ralph N Martins, Peter J Snyder, Colin L Masters, Christopher C Rowe, Victor L Villemagne, Paul Maruf. Relationships between performance on the Cogstate Brief Battery, neurodegeneration, and Aβ accumulation in cognitively normal older adults and adults with MCI. Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists. vol 30. issue 1. 2015-09-11. PMID:25467942. |
analysis of interrelationships between these alzheimer's disease markers in aβ+ cns and mcis indicated that rate of aβ accumulation was associated with rate of hippocampal atrophy (β = -0.05, p = .037), which was in turn associated independently with rate of decline in memory (β = -0.03, p = .032). |
2015-09-11 |
2023-08-13 |
Not clear |
| Shu-e Cao, Jianmin Tian, Shengyang Chen, Xiaoran Zhang, Yongqiang Zhan. Role of miR-34c in ketamine-induced neurotoxicity in neonatal mice hippocampus. Cell biology international. vol 39. issue 2. 2015-09-10. PMID:25052764. |
we have used an in vivo neonatal mouse model to induce ketamine-related neurotoxicity in the hippocampus, and found that mir-34c, a microrna associated with pathogenesis of alzheimer's disease, was significantly upregulated during ketamine-induced hippocampal neurodegeneration. |
2015-09-10 |
2023-08-13 |
mouse |
| Per Suppa, Ulrich Anker, Lothar Spies, Irene Bopp, Brigitte Rüegger-Frey, Richard Klaghofer, Carola Gocke, Harald Hampel, Sacha Beck, Ralph Bucher. Fully automated atlas-based hippocampal volumetry for detection of Alzheimer's disease in a memory clinic setting. Journal of Alzheimer's disease : JAD. vol 44. issue 1. 2015-09-10. PMID:25201782. |
fully automated atlas-based hippocampal volumetry for detection of alzheimer's disease in a memory clinic setting. |
2015-09-10 |
2023-08-13 |
Not clear |
| Per Suppa, Ulrich Anker, Lothar Spies, Irene Bopp, Brigitte Rüegger-Frey, Richard Klaghofer, Carola Gocke, Harald Hampel, Sacha Beck, Ralph Bucher. Fully automated atlas-based hippocampal volumetry for detection of Alzheimer's disease in a memory clinic setting. Journal of Alzheimer's disease : JAD. vol 44. issue 1. 2015-09-10. PMID:25201782. |
hippocampal volume is a promising biomarker to enhance the accuracy of the diagnosis of dementia due to alzheimer's disease (ad). |
2015-09-10 |
2023-08-13 |
Not clear |
| Wenjia Zhang, Xue Wang, Zijian Zhou, You Qiong L. A quantitative magnetic resonance study of the hippocampus and the temporal horn of the lateral ventricle in healthy subjects. The Journal of craniofacial surgery. vol 24. issue 3. 2015-09-09. PMID:23714936. |
hippocampal volume has been measured and used to separate the people who have alzheimer disease, stress-related psychiatric disorders such as posttraumatic stress disorder, borderline personality disorder, and schizophrenia from normal people. |
2015-09-09 |
2023-08-12 |
human |
| Yuxin Yi, Shixing Wu, Maosheng Ye, Yi Zeng, Ping Zhang, Yiqun Xi. [Effect of Aβ1-42 injection on hippocampus cells in rats and protective role of polygona-polysaccharose for Alzheimer's disease]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 39. issue 4. 2015-09-08. PMID:24820272. |
[effect of aβ1-42 injection on hippocampus cells in rats and protective role of polygona-polysaccharose for alzheimer's disease]. |
2015-09-08 |
2023-08-13 |
rat |
| Edward D Levin, Brandon J Hall, Amir H Rezvan. Heterogeneity across brain regions and neurotransmitter interactions with nicotinic effects on memory function. Current topics in behavioral neurosciences. vol 23. 2015-09-08. PMID:25655888. |
alzheimer's disease results in a dramatic decrease in hippocampal nicotinic receptor density, affecting α4β2 receptor expression most prominently. |
2015-09-08 |
2023-08-13 |
rat |