All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
William Seunghyun Sohn, Kwangsun Yoo, Duk L Na, Yong Jeon. Progressive changes in hippocampal resting-state connectivity across cognitive impairment: a cross-sectional study from normal to Alzheimer disease. Alzheimer disease and associated disorders. vol 28. issue 3. 2015-04-23. PMID:24614267. we investigate the changes in functional connectivity of the left and right hippocampus by comparing the resting-state low-frequency fluctuations in the blood oxygen level-dependent signal from these regions with relation to alzheimer disease (ad) progression. 2015-04-23 2023-08-12 Not clear
Yoori Choi, Kihwan Lee, Junghwa Ryu, Hyoun Geun Kim, A Young Jeong, Ran-Sook Woo, Jun-Ho Lee, Jin Won Hyun, Seokyung Hahn, Joung-Hun Kim, Hye-Sun Ki. Neuritin attenuates cognitive function impairments in tg2576 mouse model of Alzheimer's disease. PloS one. vol 9. issue 8. 2015-04-21. PMID:25101829. in this study, we found that the cortical and hippocampal expression of neuritin is reduced in the brains of alzheimer's disease (ad) patients and demonstrated that viral-mediated expression of neuritin in the dentate gyrus of 13-month-old tg2576 mice, an ad animal model, attenuated a deficit in learning and memory as assessed by a morris water maze test. 2015-04-21 2023-08-13 mouse
Niklas Mattsson, Philip S Insel, Michael Donohue, Susan Landau, William J Jagust, Leslie M Shaw, John Q Trojanowski, Henrik Zetterberg, Kaj Blennow, Michael W Weine. Independent information from cerebrospinal fluid amyloid-β and florbetapir imaging in Alzheimer's disease. Brain : a journal of neurology. vol 138. issue Pt 3. 2015-04-20. PMID:25541191. cerebrospinal fluid and positron emission tomography amyloid-β were measured at baseline in 769 persons [161 healthy controls, 68 subjective memory complaints, 419 mild cognitive impairment and 121 alzheimer's disease dementia, mean age 72 years (standard deviation 7 years), 47% females] and used to predict diagnosis, apoe ε4 carriage status, cerebral blood flow, cerebrospinal fluid total-tau and phosphorylated-tau levels (cross-sectionally); and hippocampal volume, fluorodeoxyglucose positron emission tomography results and alzheimer's disease assessment scale-cognitive subscale scores (longitudinally). 2015-04-20 2023-08-13 Not clear
Hai-Yan Hu, Lei Lei, Xiang Chen, Wen-Hua Wang, Xiao-Yan Zhan. [Effects of qingxin kaiqiao recipe volatile oil on expressions of GFAP and caspase-3 in the cortex and hippocampus of AD rats]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 33. issue 7. 2015-04-11. PMID:24063215. to study effects of qingxin kaiqiao recipe (qkr) and its volatile oil on the expressions of abeta(25-35) glial fibrillary acidic protein (gfap), beta-amyloid (abeta), beta-amyloid precursor protein (betaapp), and caspase-3 in the cortex and hippocampus of alzheimer's disease (ad) rats induced by injecting abeta(25-35) into the bilateral amygdala. 2015-04-11 2023-08-12 rat
Jingwen Yan, Sungeun Kim, Kwangsik Nho, Rui Chen, Shannon L Risacher, Jason H Moore, Andrew J Saykin, Li She. Hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in Alzheimer's disease. Frontiers in genetics. vol 6. 2015-04-10. PMID:25859259. hippocampal transcriptome-guided genetic analysis of correlated episodic memory phenotypes in alzheimer's disease. 2015-04-10 2023-08-13 Not clear
Nathalie Philippi, Anne Botzung, Vincent Noblet, François Rousseau, Olivier Després, Benjamin Cretin, Stéphane Kremer, Frédéric Blanc, Liliann Mannin. Impaired emotional autobiographical memory associated with right amygdalar-hippocampal atrophy in Alzheimer's disease patients. Frontiers in aging neuroscience. vol 7. 2015-04-08. PMID:25852541. we studied the influence of emotions on autobiographical memory (abm) in patients with alzheimer's disease (ad), characteristically triggering atrophy in the hippocampus and the amygdala, two crucial structures sustaining memory and emotional processing. 2015-04-08 2023-08-13 human
Marilia S Albuquerque, Ian Mahar, Maria Antonietta Davoli, Jean-Guy Chabot, Naguib Mechawar, Rémi Quirion, Slavica Kranti. Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease. Frontiers in aging neuroscience. vol 7. 2015-04-08. PMID:25852545. regional and sub-regional differences in hippocampal gabaergic neuronal vulnerability in the tgcrnd8 mouse model of alzheimer's disease. 2015-04-08 2023-08-13 mouse
Marilia S Albuquerque, Ian Mahar, Maria Antonietta Davoli, Jean-Guy Chabot, Naguib Mechawar, Rémi Quirion, Slavica Kranti. Regional and sub-regional differences in hippocampal GABAergic neuronal vulnerability in the TgCRND8 mouse model of Alzheimer's disease. Frontiers in aging neuroscience. vol 7. 2015-04-08. PMID:25852545. we have previously hypothesized that the altered excitability of hippocampal neurons in alzheimer's disease (ad), which manifests as increased in vivo susceptibility to seizures in the tgcrnd8 mouse model of ad, may be related to disruption of hippocampal gabaergic neurons. 2015-04-08 2023-08-13 mouse
Alison Spilsbury, Satomi Miwa, Johannes Attems, Gabriele Saretzk. The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 4. 2015-04-07. PMID:25632141. tert protein colocalized with mitochondria in the hippocampus of alzheimer's disease brains (braak stage vi), as well as in cultured neurons under conditions of oxidative stress. 2015-04-07 2023-08-13 mouse
Lauren D Stutzbach, Sharon X Xie, Adam C Naj, Roger Albin, Sid Gilman, Virginia M Y Lee, John Q Trojanowski, Bernie Devlin, Gerard D Schellenber. The unfolded protein response is activated in disease-affected brain regions in progressive supranuclear palsy and Alzheimer's disease. Acta neuropathologica communications. vol 1. 2015-03-31. PMID:24252572. recently, several groups noted upr activation in alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis, multiple system atrophy, and in the hippocampus and substantia nigra of psp subjects. 2015-03-31 2023-08-12 human
Laurent Younes, Marilyn Albert, Michael I Mille. Inferring changepoint times of medial temporal lobe morphometric change in preclinical Alzheimer's disease. NeuroImage. Clinical. vol 5. 2015-03-31. PMID:25101236. this paper uses diffeomorphometry methods to quantify the order in which statistically significant morphometric change occurs in three medial temporal lobe regions, the amygdala, entorhinal cortex (erc), and hippocampus among subjects with symptomatic and preclinical alzheimer's disease (ad). 2015-03-31 2023-08-13 human
Claire Boutet, Marie Chupin, Stéphane Lehéricy, Linda Marrakchi-Kacem, Stéphane Epelbaum, Cyril Poupon, Christopher Wiggins, Alexandre Vignaud, Dominique Hasboun, Bénédicte Defontaines, Olivier Hanon, Bruno Dubois, Marie Sarazin, Lucie Hertz-Pannier, Olivier Collio. Detection of volume loss in hippocampal layers in Alzheimer's disease using 7 T MRI: a feasibility study. NeuroImage. Clinical. vol 5. 2015-03-31. PMID:25161900. detection of volume loss in hippocampal layers in alzheimer's disease using 7 t mri: a feasibility study. 2015-03-31 2023-08-13 human
Claire Boutet, Marie Chupin, Stéphane Lehéricy, Linda Marrakchi-Kacem, Stéphane Epelbaum, Cyril Poupon, Christopher Wiggins, Alexandre Vignaud, Dominique Hasboun, Bénédicte Defontaines, Olivier Hanon, Bruno Dubois, Marie Sarazin, Lucie Hertz-Pannier, Olivier Collio. Detection of volume loss in hippocampal layers in Alzheimer's disease using 7 T MRI: a feasibility study. NeuroImage. Clinical. vol 5. 2015-03-31. PMID:25161900. in alzheimer's disease (ad), the hippocampus is an early site of tau pathology and neurodegeneration. 2015-03-31 2023-08-13 human
Christopher S Casley, Viktor Lakics, Hyoung-gon Lee, Lisa M Broad, Theresa A Day, Tricia Cluett, Mark A Smith, Michael J O'Neill, Ann E Kingsto. Up-regulation of astrocyte metabotropic glutamate receptor 5 by amyloid-β peptide. Brain research. vol 1260. 2015-03-30. PMID:19401173. the changes observed in vitro were consistent with results obtained from human alzheimer's disease (ad) patients.immunostaining for mglu5 receptors was increased on astrocytes which were colocalized with aβ plaques in hippocampal tissue from ad patients compared to age-matched controls. 2015-03-30 2023-08-12 human
Rong Zhao, Stephanie W Fowler, Angie C A Chiang, Daoyun Ji, Joanna L Jankowsk. Impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of Alzheimer's disease. Hippocampus. vol 24. issue 8. 2015-03-30. PMID:24752989. impairments in experience-dependent scaling and stability of hippocampal place fields limit spatial learning in a mouse model of alzheimer's disease. 2015-03-30 2023-08-13 mouse
Rasoul Ghasemi, Asadollah Zarifkar, Karim Rastegar, Nader maghsoudi, Maryam Moosav. Insulin protects against Aβ-induced spatial memory impairment, hippocampal apoptosis and MAPKs signaling disruption. Neuropharmacology. vol 85. 2015-03-30. PMID:24881967. alzheimer disease (ad) is a progressive neurodegenerative disease characterized by extracellular deposits of beta amyloid (aβ) and neuronal loss particularly in the hippocampus. 2015-03-30 2023-08-13 rat
Selvaraju Subash, Musthafa Mohamed Essa, Abdullah Al-Asmi, Samir Al-Adawi, Ragini Vaishna. Chronic dietary supplementation of 4% figs on the modification of oxidative stress in Alzheimer's disease transgenic mouse model. BioMed research international. vol 2014. 2015-03-30. PMID:25050360. we assessed the changes in the plasma aβ, oxidative stress/antioxidants, and membrane bound enzymes in the cerebral cortex and hippocampus of alzheimer's disease (ad) transgenic mice (tg2576) after dietary supplementation of omani figs fruits for 15 months along with spatial memory and learning test. 2015-03-30 2023-08-13 mouse
Katherine A Price, Merina Varghese, Allison Sowa, Frank Yuk, Hannah Brautigam, Michelle E Ehrlich, Dara L Dickstei. Altered synaptic structure in the hippocampus in a mouse model of Alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. Molecular neurodegeneration. vol 9. 2015-03-30. PMID:25312309. altered synaptic structure in the hippocampus in a mouse model of alzheimer's disease with soluble amyloid-β oligomers and no plaque pathology. 2015-03-30 2023-08-13 mouse
Jing Jiang, Kai Gao, Yuan Zhou, Anping Xu, Suhua Shi, Gang Liu, Zhigang L. Electroacupuncture Treatment Improves Learning-Memory Ability and Brain Glucose Metabolism in a Mouse Model of Alzheimer's Disease: Using Morris Water Maze and Micro-PET. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-03-30. PMID:25821477. alzheimer's disease (ad) causes progressive hippocampus dysfunctions leading to the impairment of learning and memory ability and low level of uptake rate of glucose in hippocampus. 2015-03-30 2023-08-13 mouse
Ying Liu, Jin-Tai Yu, Hui-Fu Wang, Pei-Ran Han, Chen-Chen Tan, Chong Wang, Xiang-Fei Meng, Shannon L Risacher, Andrew J Saykin, Lan Ta. APOE genotype and neuroimaging markers of Alzheimer's disease: systematic review and meta-analysis. Journal of neurology, neurosurgery, and psychiatry. vol 86. issue 2. 2015-03-27. PMID:24838911. we aimed to examine the association of apolipoprotein e (apoe) ɛ4 genotype with neuroimaging markers of alzheimer's disease: hippocampal volume, brain amyloid deposition and cerebral metabolism. 2015-03-27 2023-08-13 Not clear