| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Robert E Hampson, Dong Song, Ioan Opris, Lucas M Santos, Dae C Shin, Greg A Gerhardt, Vasilis Z Marmarelis, Theodore W Berger, Sam A Deadwyle. Facilitation of memory encoding in primate hippocampus by a neuroprosthesis that promotes task-specific neural firing. Journal of neural engineering. vol 10. issue 6. 2014-08-14. PMID:24216292. |
memory accuracy is a major problem in human disease and is the primary factor that defines alzheimer's, ageing and dementia resulting from impaired hippocampal function in the medial temporal lobe. |
2014-08-14 |
2023-08-12 |
human |
| Muriel Boucart, Gauthier Calais, Quentin Lenoble, Christine Moroni, Florence Pasquie. Differential processing of natural scenes in posterior cortical atrophy and in Alzheimer's disease, as measured with a saccade choice task. Frontiers in integrative neuroscience. vol 8. 2014-08-14. PMID:25120440. |
atrophy of the medial temporal lobe structures that support scene perception and the binding of an object to its context (i.e., the hippocampus and the parahippocampal cortex) appears early in the course of alzheimer's disease (ad). |
2014-08-14 |
2023-08-13 |
human |
| Kerrie Hayes, Richard Buist, Trevor J Vincent, Jonathan D Thiessen, Yanbo Zhang, Handi Zhang, Junhui Wang, Arthur R Summers, Jiming Kong, Xin-Min Li, Melanie Marti. Comparison of manual and semi-automated segmentation methods to evaluate hippocampus volume in APP and PS1 transgenic mice obtained via in vivo magnetic resonance imaging. Journal of neuroscience methods. vol 221. 2014-08-13. PMID:24091139. |
a hallmark pathological feature of alzheimer's disease is atrophy of the hippocampus, which is an early biomarker of the disease. |
2014-08-13 |
2023-08-12 |
mouse |
| Keith A Wesnes, Peter Annas, Hans Basun, Chris Edgar, Kaj Blenno. Performance on a pattern separation task by Alzheimer's patients shows possible links between disrupted dentate gyrus activity and apolipoprotein E ∈4 status and cerebrospinal fluid amyloid-β42 levels. Alzheimer's research & therapy. vol 6. issue 2. 2014-08-12. PMID:24735568. |
emerging evidence suggests that decreased adult hippocampal neurogenesis represents an early critical event in the course of alzheimer's disease (ad). |
2014-08-12 |
2023-08-13 |
mouse |
| Andrew J Irving, Jenni Harve. Leptin regulation of hippocampal synaptic function in health and disease. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1633. 2014-08-11. PMID:24298156. |
however, the ability of leptin to regulate hippocampal synaptic function markedly declines with age and aberrant leptin function has been linked to neurodegenerative disorders such as alzheimer's disease (ad). |
2014-08-11 |
2023-08-12 |
Not clear |
| Jared Rowley, Vladimir Fonov, Ona Wu, Simon Fristed Eskildsen, Dorothee Schoemaker, Liyong Wu, Sara Mohades, Monica Shin, Viviane Sziklas, Laksanun Cheewakriengkrai, Amir Shmuel, Alain Dagher, Serge Gauthier, Pedro Rosa-Net. White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer's disease. PloS one. vol 8. issue 9. 2014-08-07. PMID:24086371. |
white matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and alzheimer's disease. |
2014-08-07 |
2023-08-12 |
human |
| Jared Rowley, Vladimir Fonov, Ona Wu, Simon Fristed Eskildsen, Dorothee Schoemaker, Liyong Wu, Sara Mohades, Monica Shin, Viviane Sziklas, Laksanun Cheewakriengkrai, Amir Shmuel, Alain Dagher, Serge Gauthier, Pedro Rosa-Net. White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer's disease. PloS one. vol 8. issue 9. 2014-08-07. PMID:24086371. |
the purpose of this project was to evaluate white matter degeneration and its impact on hippocampal structural connectivity in patients with amnestic mild cognitive impairment, non-amnestic mild cognitive impairment and alzheimer's disease. |
2014-08-07 |
2023-08-12 |
human |
| Jared Rowley, Vladimir Fonov, Ona Wu, Simon Fristed Eskildsen, Dorothee Schoemaker, Liyong Wu, Sara Mohades, Monica Shin, Viviane Sziklas, Laksanun Cheewakriengkrai, Amir Shmuel, Alain Dagher, Serge Gauthier, Pedro Rosa-Net. White matter abnormalities and structural hippocampal disconnections in amnestic mild cognitive impairment and Alzheimer's disease. PloS one. vol 8. issue 9. 2014-08-07. PMID:24086371. |
reduced structural connectivity was found in the hippocampal connections to temporal, inferior parietal, posterior cingulate and frontal regions only in the alzheimer's group. |
2014-08-07 |
2023-08-12 |
human |
| Anand M Iyer, Jackelien van Scheppingen, Ivan Milenkovic, Jasper J Anink, Homa Adle-Biassette, Gabor G Kovacs, Eleonora Aronic. mTOR Hyperactivation in down syndrome hippocampus appears early during development. Journal of neuropathology and experimental neurology. vol 73. issue 7. 2014-08-06. PMID:24918639. |
moreover, the expression patterns of mtor components in adult ds hippocampus support its association with alzheimer disease-related histopathologic changes. |
2014-08-06 |
2023-08-13 |
human |
| Tiina Maria Pirttimaki, Neela Krushna Codadu, Alia Awni, Pandey Pratik, David Andrew Nagel, Eric James Hill, Kelly Tennyson Dineley, H Rheinallt Parr. α7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model. PloS one. vol 8. issue 11. 2014-08-05. PMID:24312364. |
we and others have shown that amyloid-β (aβ), the toxic trigger for alzheimer's disease (ad), interacts with hippocampal α7 nicotinic acetylcholine receptors (nachrs). |
2014-08-05 |
2023-08-12 |
mouse |
| Carlos Aguilar, J-Sebastian Muehlboeck, Patrizia Mecocci, Bruno Vellas, Magda Tsolaki, Iwona Kloszewska, Hilkka Soininen, Simon Lovestone, Lars-Olof Wahlund, Andrew Simmons, Eric Westma. Application of a MRI based index to longitudinal atrophy change in Alzheimer disease, mild cognitive impairment and healthy older individuals in the AddNeuroMed cohort. Frontiers in aging neuroscience. vol 6. 2014-07-29. PMID:25071554. |
cross sectional studies of patients at risk of developing alzheimer disease (ad) have identified several brain regions known to be prone to degeneration suitable as biomarkers, including hippocampal, ventricular, and whole brain volume. |
2014-07-29 |
2023-08-13 |
human |
| Bai-Yun Zeng, Sarah Salvage, Peter Jenne. Effect and mechanism of acupuncture on Alzheimer's disease. International review of neurobiology. vol 111. 2014-07-28. PMID:24215923. |
in alzheimer's animal models, acupuncture stimulation at acupoints enhances cholinergic neurotransmission, trophic factor releasing, reduces apoptotic and oxidative damages, improves synaptic plasticity and decreases the levels of aβ proteins in the hippocampus and relevant brain regions. |
2014-07-28 |
2023-08-12 |
human |
| Antonella Caccamo, Vito De Pinto, Angela Messina, Caterina Branca, Salvatore Odd. Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 23. 2014-07-25. PMID:24899720. |
genetic reduction of mammalian target of rapamycin ameliorates alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature. |
2014-07-25 |
2023-08-13 |
mouse |
| Hai-Yan Hu, Zhi-Hui Cui, Hui-Qin Li, Yi-Ru Wang, Xiang Chen, Ji-Huang Li, Dong-Mei Xv, Guo-Qing Zhen. Fumanjian, a Classic Chinese Herbal Formula, Can Ameliorate the Impairment of Spatial Learning and Memory through Apoptotic Signaling Pathway in the Hippocampus of Rats with Aβ 1-40 -Induced Alzheimer's Disease. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2014-07-22. PMID:25050129. |
fumanjian, a classic chinese herbal formula, can ameliorate the impairment of spatial learning and memory through apoptotic signaling pathway in the hippocampus of rats with aβ 1-40 -induced alzheimer's disease. |
2014-07-22 |
2023-08-13 |
rat |
| Jeanine Manuella Kamsu, Jean-Marc Constans, Franck Lamberton, Patrick Courtheoux, Pierre Denise, Bruno Philoxene, Maelle Coquemont, Stephane Besnar. Structural layers of ex vivo rat hippocampus at 7T MRI. PloS one. vol 8. issue 9. 2014-07-18. PMID:24086700. |
magnetic resonance imaging (mri) applied to the hippocampus is challenging in studies of the neurophysiology of memory and the physiopathology of numerous diseases such as epilepsy, alzheimer's disease, ischemia, and depression. |
2014-07-18 |
2023-08-12 |
rat |
| M Mascalchi, A Ginestroni, V Bessi, N Toschi, S Padiglioni, S Ciulli, C Tessa, M Giannelli, L Bracco, S Diciott. Regional analysis of the magnetization transfer ratio of the brain in mild Alzheimer disease and amnestic mild cognitive impairment. AJNR. American journal of neuroradiology. vol 34. issue 11. 2014-07-11. PMID:23744687. |
manually drawn voi-based analysis shows a decrease in magnetization transfer ratio in the hippocampus of patients with alzheimer disease. |
2014-07-11 |
2023-08-12 |
Not clear |
| John K Young, Thomas Heinbockel, Marjorie C Gondré-Lewi. Astrocyte fatty acid binding protein-7 is a marker for neurogenic niches in the rat hippocampus. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23996503. |
because fabp7+ astrocytes are particularly abundant in the hippocampus, and since the gene for fabp7 has been linked to alzheimer's disease, age-related changes in fabp7+ astrocytes (mitochondrial degeneration) may be relevant to age-associated disorders of the hippocampus. |
2014-07-09 |
2023-08-12 |
rat |
| E Orta-Salazar, A Feria-Velasco, G I Medina-Aguirre, S Díaz-Cintr. [Morphological analysis of the hippocampal region associated with an innate behaviour task in the transgenic mouse model (3xTg-AD) for Alzheimer disease]. Neurologia (Barcelona, Spain). vol 28. issue 8. 2014-07-02. PMID:23972735. |
[morphological analysis of the hippocampal region associated with an innate behaviour task in the transgenic mouse model (3xtg-ad) for alzheimer disease]. |
2014-07-02 |
2023-08-12 |
mouse |
| Doaa M Abo El-Khair, Fatma El-Nabawia A El-Safti, Hanaa Z Nooh, Abeer E El-Meh. A comparative study on the effect of high cholesterol diet on the hippocampal CA1 area of adult and aged rats. Anatomy & cell biology. vol 47. issue 2. 2014-07-02. PMID:24987548. |
moreover, the high cholesterol diet aged rats showed aggravation of senility changes of the hippocampus together with alzheimer like pathological changes. |
2014-07-02 |
2023-08-13 |
rat |
| Stephan Müller, Christian Mychajliw, Martin Hautzinger, Andreas J Fallgatter, Ralf Saur, Thomas Leyh. Memory for past public events depends on retrieval frequency but not memory age in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 38. issue 2. 2014-06-27. PMID:23969995. |
alzheimer's disease (ad) is characterized by retrograde memory deficits primarily caused by dysfunction of the hippocampal complex. |
2014-06-27 |
2023-08-12 |
Not clear |