All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Wenwen Yin, Ke Wan, Wenhao Zhu, Xia Zhou, Yating Tang, Wenhui Zheng, Jing Cao, Yu Song, Han Zhao, Xiaoqun Zhu, Zhongwu Su. Bilateral Hippocampal Volume Mediated the Relationship Between Plasma BACE1 Concentration and Memory Function in the Early Stage of Alzheimer's Disease: A Cross-Sectional Study. Journal of Alzheimer's disease : JAD. 2023-02-27. PMID:36847009. bilateral hippocampal volume mediated the relationship between plasma bace1 concentration and memory function in the early stage of alzheimer's disease: a cross-sectional study. 2023-02-27 2023-08-14 Not clear
Fabiola Paciello, Cristian Ripoli, Anna Rita Fetoni, Claudio Grass. Redox Imbalance as a Common Pathogenic Factor Linking Hearing Loss and Cognitive Decline. Antioxidants (Basel, Switzerland). vol 12. issue 2. 2023-02-25. PMID:36829891. at the same time, increased oxidative stress in medio-temporal brain regions, including the hippocampus, is a hallmark of neurodegenerative disorders like alzheimer's disease. 2023-02-25 2023-08-14 Not clear
Robert G Hinshaw, Maren K Schroeder, Jason Ciola, Curran Varma, Brianna Colletti, Bin Liu, Grace Geyu Liu, Qiaoqiao Shi, Jacqueline P Williams, M Kerry O'Banion, Barbara J Caldarone, Cynthia A Lemer. High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835027. in general, the alzheimer's model mice were more prone than their wildtype littermates to radiation-induced behavior changes, and hippocampal staining for amyloid beta pathology and microglial activation in these mice revealed a dose-dependent reduction in males but not in females. 2023-02-25 2023-08-14 mouse
Lilach Soreq, Hannah Bird, Wael Mohamed, John Hard. Single-cell RNA sequencing analysis of human Alzheimer's disease brain samples reveals neuronal and glial specific cells differential expression. PloS one. vol 18. issue 2. 2023-02-24. PMID:36827281. thus, to identify distinct transcriptional networks impacted into distinct neuronal populations in alzheimer, we surveyed gene expression differences in over 25,000 single-nuclei collected from the brains of two alzheimer's in disease patients in braak stage i and ii and age- and gender-matched controls hippocampal brain samples. 2023-02-24 2023-08-14 human
Azam Abedi, Tahereh Foroutan, Leila Mohaghegh Shalmani, Leila Dargah. Sex-specific effects of high-fat diet on rat brain glucose metabolism and early-onset dementia symptoms. Mechanisms of ageing and development. 2023-02-24. PMID:36828273. analysis of 15 genes related to glucose metabolism and alzheimer's pathology, in the hippocampus, showed that expression of glut3, irs2, and ide is significantly reduced in hfd male rats. 2023-02-24 2023-08-14 rat
Faizal Hajamohideen, Noushath Shaffi, Mufti Mahmud, Karthikeyan Subramanian, Arwa Al Sariri, Viswan Vimbi, Abdelhamid Abdessela. Four-way classification of Alzheimer's disease using deep Siamese convolutional neural network with triplet-loss function. Brain informatics. vol 10. issue 1. 2023-02-22. PMID:36806042. alzheimer's disease (ad) is a neurodegenerative disease that causes irreversible damage to several brain regions, including the hippocampus causing impairment in cognition, function, and behaviour. 2023-02-22 2023-08-14 Not clear
Rowan Saloner, Emily W Paolillo, Kevin J Wojta, Corrina Fonseca, Eva Q Gontrum, Argentina Lario-Lago, Gil D Rabinovici, Jennifer S Yokoyama, Jessica E Rexach, Joel H Kramer, Kaitlin B Casalett. Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-02-22. PMID:36807763. we tested sex-dependent associations of variation in the snap-25 gene, which encodes a presynaptic protein involved in hippocampal plasticity and memory, on cognitive and alzheimer's disease (ad) neuroimaging outcomes in clinically normal adults. 2023-02-22 2023-08-14 Not clear
Sehwan Kim, Chanchal Sharma, Minsang Shin, Hyung-Jun Kim, Jaekwang Kim, Sang Ryong Ki. pKr-2 induces neurodegeneration Brain, behavior, & immunity - health. vol 28. 2023-02-17. PMID:36798617. pkr-2 induces neurodegeneration we recently demonstrated that prothrombin kringle-2 (pkr-2) derived from blood-brain barrier (bbb) disruption could induce hippocampal neurodegeneration and object recognition impairment through neurotoxic inflammatory responses in the five familial alzheimer's disease mutation (5xfad) mice. 2023-02-17 2023-08-14 mouse
Xiang Hu, Maria Meier, Jens Pruessne. Challenges and opportunities of diagnostic markers of Alzheimer's disease based on structural magnetic resonance imaging. Brain and behavior. 2023-02-16. PMID:36795041. this article aimed to carry out a narrative literature review of early diagnostic markers of alzheimer's disease (ad) based on both micro and macro levels of pathology, indicating the shortcomings of current biomarkers and proposing a novel biomarker of structural integrity that associates the hippocampus and adjacent ventricle together. 2023-02-16 2023-08-14 Not clear
Elisabeth Black, Abbey Rasch, Tyler Wimmer, Alivia Li, Amanda Araujo, Steve Cieslak, Kevin S Steed, Rajan D Adhikari, Jonathan J Wisco, Bre Anna Hutchinso. The Effects of Age, Genotype, and Diet on Hippocampal Subfield Iron Dysregulation and Alzheimer's Disease Biomarkers in an ApoE Mouse Model. The European journal of neuroscience. 2023-02-13. PMID:36775930. the effects of age, genotype, and diet on hippocampal subfield iron dysregulation and alzheimer's disease biomarkers in an apoe mouse model. 2023-02-13 2023-08-14 mouse
Elisabeth Black, Abbey Rasch, Tyler Wimmer, Alivia Li, Amanda Araujo, Steve Cieslak, Kevin S Steed, Rajan D Adhikari, Jonathan J Wisco, Bre Anna Hutchinso. The Effects of Age, Genotype, and Diet on Hippocampal Subfield Iron Dysregulation and Alzheimer's Disease Biomarkers in an ApoE Mouse Model. The European journal of neuroscience. 2023-02-13. PMID:36775930. our findings also suggest a diet-genotype interaction which affects levels of specific alzheimer's disease biomarkers in the hippocampus. 2023-02-13 2023-08-14 mouse
Tommaso Cassano, Flavia Giamogante, Silvio Calcagnini, Adele Romano, Angelo Michele Lavecchia, Francesca Inglese, Giuliano Paglia, Vidyasagar Naik Bukke, Antonino Davide Romano, Marzia Friuli, Fabio Altieri, Silvana Gaetan. PDIA3 Expression Is Altered in the Limbic Brain Regions of Triple-Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769334. in the present study, we used a mouse model of alzheimer's disease (ad) (3×tg-ad mice) to longitudinally analyse the expression level of pdia3, a protein disulfide isomerase and endoplasmic reticulum (er) chaperone, in selected brain limbic areas strongly affected by ad-pathology (amygdala, entorhinal cortex, dorsal and ventral hippocampus). 2023-02-11 2023-08-14 mouse
Gwang-Won Kim, Kwangsung Park, Yun-Hyeon Kim, Gwang-Woo Jeon. Increased Hippocampal-Inferior Temporal Gyrus White Matter Connectivity following Donepezil Treatment in Patients with Early Alzheimer's Disease: A Diffusion Tensor Probabilistic Tractography Study. Journal of clinical medicine. vol 12. issue 3. 2023-02-11. PMID:36769615. the incidence of alzheimer's disease (ad) has been increasing each year, and a defective hippocampus has been primarily associated with an early stage of ad. 2023-02-11 2023-08-14 Not clear
Weixue Xiong, Jiahui Cai, Xueqin Wang, Haizhu Ta. Genetic architecture of hippocampus subfields volumes in Alzheimer's disease. CNS neuroscience & therapeutics. 2023-02-09. PMID:36756718. genetic architecture of hippocampus subfields volumes in alzheimer's disease. 2023-02-09 2023-08-14 Not clear
Weixue Xiong, Jiahui Cai, Xueqin Wang, Haizhu Ta. Genetic architecture of hippocampus subfields volumes in Alzheimer's disease. CNS neuroscience & therapeutics. 2023-02-09. PMID:36756718. the volume reductions in hippocampal subfields have been demonstrated to be linked with alzheimer's disease (ad). 2023-02-09 2023-08-14 Not clear
Weixue Xiong, Jiahui Cai, Xueqin Wang, Haizhu Ta. Genetic architecture of hippocampus subfields volumes in Alzheimer's disease. CNS neuroscience & therapeutics. 2023-02-09. PMID:36756718. the aim of our study is to investigate the hippocampal subfields' genetic architecture based on the alzheimer's disease neuroimaging initiative (adni) data set. 2023-02-09 2023-08-14 Not clear
Xiao-Hui Li, Hong-Can Zhu, Xue-Min Cui, Wang Wang, Lin Yang, Li-Bo Wang, Neng-Wei Hu, Dong-Xiao Dua. Death-associated protein kinase 1 is associated with cognitive dysfunction in major depressive disorder. Neural regeneration research. vol 18. issue 8. 2023-02-08. PMID:36751808. we previously showed that death-associated protein kinase 1 (dapk1) expression is increased in hippocampal tissue in a mouse model of major depressive disorde and is related to cognitive dysfunction in alzheimer's disease. 2023-02-08 2023-08-14 mouse
Jamie M Walker, William Goette, Kurt Farrell, Megan A Iida, Esma Karlovich, Charles L White, John F Crary, Timothy E Richardso. The relationship between hippocampal amyloid beta burden and spatial distribution of neurofibrillary degeneration. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-02-04. PMID:36738450. neurofibrillary degeneration in alzheimer's disease (ad) typically involves the entorhinal cortex and ca1 subregion of the hippocampus early in the disease process, whereas in primary age-related tauopathy (part), there is an early selective vulnerability of the ca2 subregion. 2023-02-04 2023-08-14 Not clear
Evgenia Salta, Orly Lazarov, Carlos P Fitzsimons, Rudolph Tanzi, Paul J Lucassen, Se Hoon Cho. Adult hippocampal neurogenesis in Alzheimer's disease: A roadmap to clinical relevance. Cell stem cell. vol 30. issue 2. 2023-02-03. PMID:36736288. adult hippocampal neurogenesis in alzheimer's disease: a roadmap to clinical relevance. 2023-02-03 2023-08-14 Not clear
Evgenia Salta, Orly Lazarov, Carlos P Fitzsimons, Rudolph Tanzi, Paul J Lucassen, Se Hoon Cho. Adult hippocampal neurogenesis in Alzheimer's disease: A roadmap to clinical relevance. Cell stem cell. vol 30. issue 2. 2023-02-03. PMID:36736288. adult hippocampal neurogenesis (ahn) drops sharply during early stages of alzheimer's disease (ad), via unknown mechanisms, and correlates with cognitive status in ad patients. 2023-02-03 2023-08-14 Not clear