| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eid Abo Hamza, Ahmed A Moustafa, Richard Tindle, Rasu Karki, Shahed Nalla, Mohamed S Hamid, Mohamad El Ha. Effect of APOE4 Allele and Gender on the Rate of Atrophy in the Hippocampus, Entorhinal Cortex, and Fusiform Gyrus in Alzheimer's Disease. Current Alzheimer research. 2023-03-09. PMID:36892120. |
the hippocampus, entorhinal cortex, and fusiform gyrus are brain areas that deteriorate during early-stage alzheimer's disease (ad). |
2023-03-09 |
2023-08-14 |
Not clear |
| Yiyu Zhang, Hongming Li, Qiang Zhen. A comprehensive characterization of hippocampal feature ensemble serves as individualized brain signature for Alzheimer's disease: deep learning analysis in 3238 participants worldwide. European radiology. 2023-03-09. PMID:36892643. |
a comprehensive characterization of hippocampal feature ensemble serves as individualized brain signature for alzheimer's disease: deep learning analysis in 3238 participants worldwide. |
2023-03-09 |
2023-08-14 |
human |
| Yiyu Zhang, Hongming Li, Qiang Zhen. A comprehensive characterization of hippocampal feature ensemble serves as individualized brain signature for Alzheimer's disease: deep learning analysis in 3238 participants worldwide. European radiology. 2023-03-09. PMID:36892643. |
hippocampal characterization is one of the most significant hallmarks of alzheimer's disease (ad); rather, the single-level feature is insufficient. |
2023-03-09 |
2023-08-14 |
human |
| Yujuan Zhou, Xu Wang, Yingying Liu, Yulu Gu, Renjun Gu, Geng Zhang, Qing Li. Mechanisms of abnormal adult hippocampal neurogenesis in Alzheimer's disease. Frontiers in neuroscience. vol 17. 2023-03-06. PMID:36875663. |
mechanisms of abnormal adult hippocampal neurogenesis in alzheimer's disease. |
2023-03-06 |
2023-08-14 |
Not clear |
| Yi-Ying Wang, Yu-Ning Zhou, Lin Jiang, Shun Wang, Lin Zhu, Shan-Shan Zhang, Hao Yang, Qi He, Li Liu, Yu-Han Xie, Xin Liang, Jing Tang, Feng-Lei Chao, Yong Tan. Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice. Experimental neurology. 2023-03-05. PMID:36871860. |
alzheimer's disease (ad) is closely related to hippocampal synapse loss, which can be alleviated by running exercise. |
2023-03-05 |
2023-08-14 |
mouse |
| Clara Muñoz-Castro, Marina Mejias-Ortega, Elisabeth Sanchez-Mejias, Victoria Navarro, Laura Trujillo-Estrada, Sebastian Jimenez, Juan Antonio Garcia-Leon, Juan Jose Fernandez-Valenzuela, Maria Virtudes Sanchez-Mico, Carmen Romero-Molina, Ines Moreno-Gonzalez, David Baglietto-Vargas, Marisa Vizuete, Antonia Gutierrez, Javier Vitoric. Monocyte-derived cells invade brain parenchyma and amyloid plaques in human Alzheimer's disease hippocampus. Acta neuropathologica communications. vol 11. issue 1. 2023-03-01. PMID:36855152. |
monocyte-derived cells invade brain parenchyma and amyloid plaques in human alzheimer's disease hippocampus. |
2023-03-01 |
2023-08-14 |
human |
| Kotaro Mizut. [Visualization of the functional neural circuit breakdown process in a mouse model of Alzheimer's disease and application to the development of new therapies]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 158. issue 2. 2023-03-01. PMID:36858494. |
alzheimer's disease (ad) patients cause cognitive impairment in time and space as early symptoms, in which the hippocampus plays an essential role. |
2023-03-01 |
2023-08-14 |
mouse |
| Wenwen Yin, Ke Wan, Wenhao Zhu, Xia Zhou, Yating Tang, Wenhui Zheng, Jing Cao, Yu Song, Han Zhao, Xiaoqun Zhu, Zhongwu Su. Bilateral Hippocampal Volume Mediated the Relationship Between Plasma BACE1 Concentration and Memory Function in the Early Stage of Alzheimer's Disease: A Cross-Sectional Study. Journal of Alzheimer's disease : JAD. 2023-02-27. PMID:36847009. |
bilateral hippocampal volume mediated the relationship between plasma bace1 concentration and memory function in the early stage of alzheimer's disease: a cross-sectional study. |
2023-02-27 |
2023-08-14 |
Not clear |
| Fabiola Paciello, Cristian Ripoli, Anna Rita Fetoni, Claudio Grass. Redox Imbalance as a Common Pathogenic Factor Linking Hearing Loss and Cognitive Decline. Antioxidants (Basel, Switzerland). vol 12. issue 2. 2023-02-25. PMID:36829891. |
at the same time, increased oxidative stress in medio-temporal brain regions, including the hippocampus, is a hallmark of neurodegenerative disorders like alzheimer's disease. |
2023-02-25 |
2023-08-14 |
Not clear |
| Robert G Hinshaw, Maren K Schroeder, Jason Ciola, Curran Varma, Brianna Colletti, Bin Liu, Grace Geyu Liu, Qiaoqiao Shi, Jacqueline P Williams, M Kerry O'Banion, Barbara J Caldarone, Cynthia A Lemer. High-Energy, Whole-Body Proton Irradiation Differentially Alters Long-Term Brain Pathology and Behavior Dependent on Sex and Alzheimer's Disease Mutations. International journal of molecular sciences. vol 24. issue 4. 2023-02-25. PMID:36835027. |
in general, the alzheimer's model mice were more prone than their wildtype littermates to radiation-induced behavior changes, and hippocampal staining for amyloid beta pathology and microglial activation in these mice revealed a dose-dependent reduction in males but not in females. |
2023-02-25 |
2023-08-14 |
mouse |
| Lilach Soreq, Hannah Bird, Wael Mohamed, John Hard. Single-cell RNA sequencing analysis of human Alzheimer's disease brain samples reveals neuronal and glial specific cells differential expression. PloS one. vol 18. issue 2. 2023-02-24. PMID:36827281. |
thus, to identify distinct transcriptional networks impacted into distinct neuronal populations in alzheimer, we surveyed gene expression differences in over 25,000 single-nuclei collected from the brains of two alzheimer's in disease patients in braak stage i and ii and age- and gender-matched controls hippocampal brain samples. |
2023-02-24 |
2023-08-14 |
human |
| Azam Abedi, Tahereh Foroutan, Leila Mohaghegh Shalmani, Leila Dargah. Sex-specific effects of high-fat diet on rat brain glucose metabolism and early-onset dementia symptoms. Mechanisms of ageing and development. 2023-02-24. PMID:36828273. |
analysis of 15 genes related to glucose metabolism and alzheimer's pathology, in the hippocampus, showed that expression of glut3, irs2, and ide is significantly reduced in hfd male rats. |
2023-02-24 |
2023-08-14 |
rat |
| Faizal Hajamohideen, Noushath Shaffi, Mufti Mahmud, Karthikeyan Subramanian, Arwa Al Sariri, Viswan Vimbi, Abdelhamid Abdessela. Four-way classification of Alzheimer's disease using deep Siamese convolutional neural network with triplet-loss function. Brain informatics. vol 10. issue 1. 2023-02-22. PMID:36806042. |
alzheimer's disease (ad) is a neurodegenerative disease that causes irreversible damage to several brain regions, including the hippocampus causing impairment in cognition, function, and behaviour. |
2023-02-22 |
2023-08-14 |
Not clear |
| Rowan Saloner, Emily W Paolillo, Kevin J Wojta, Corrina Fonseca, Eva Q Gontrum, Argentina Lario-Lago, Gil D Rabinovici, Jennifer S Yokoyama, Jessica E Rexach, Joel H Kramer, Kaitlin B Casalett. Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-02-22. PMID:36807763. |
we tested sex-dependent associations of variation in the snap-25 gene, which encodes a presynaptic protein involved in hippocampal plasticity and memory, on cognitive and alzheimer's disease (ad) neuroimaging outcomes in clinically normal adults. |
2023-02-22 |
2023-08-14 |
Not clear |
| Sehwan Kim, Chanchal Sharma, Minsang Shin, Hyung-Jun Kim, Jaekwang Kim, Sang Ryong Ki. pKr-2 induces neurodegeneration Brain, behavior, & immunity - health. vol 28. 2023-02-17. PMID:36798617. |
pkr-2 induces neurodegeneration we recently demonstrated that prothrombin kringle-2 (pkr-2) derived from blood-brain barrier (bbb) disruption could induce hippocampal neurodegeneration and object recognition impairment through neurotoxic inflammatory responses in the five familial alzheimer's disease mutation (5xfad) mice. |
2023-02-17 |
2023-08-14 |
mouse |
| Xiang Hu, Maria Meier, Jens Pruessne. Challenges and opportunities of diagnostic markers of Alzheimer's disease based on structural magnetic resonance imaging. Brain and behavior. 2023-02-16. PMID:36795041. |
this article aimed to carry out a narrative literature review of early diagnostic markers of alzheimer's disease (ad) based on both micro and macro levels of pathology, indicating the shortcomings of current biomarkers and proposing a novel biomarker of structural integrity that associates the hippocampus and adjacent ventricle together. |
2023-02-16 |
2023-08-14 |
Not clear |
| Elisabeth Black, Abbey Rasch, Tyler Wimmer, Alivia Li, Amanda Araujo, Steve Cieslak, Kevin S Steed, Rajan D Adhikari, Jonathan J Wisco, Bre Anna Hutchinso. The Effects of Age, Genotype, and Diet on Hippocampal Subfield Iron Dysregulation and Alzheimer's Disease Biomarkers in an ApoE Mouse Model. The European journal of neuroscience. 2023-02-13. PMID:36775930. |
the effects of age, genotype, and diet on hippocampal subfield iron dysregulation and alzheimer's disease biomarkers in an apoe mouse model. |
2023-02-13 |
2023-08-14 |
mouse |
| Elisabeth Black, Abbey Rasch, Tyler Wimmer, Alivia Li, Amanda Araujo, Steve Cieslak, Kevin S Steed, Rajan D Adhikari, Jonathan J Wisco, Bre Anna Hutchinso. The Effects of Age, Genotype, and Diet on Hippocampal Subfield Iron Dysregulation and Alzheimer's Disease Biomarkers in an ApoE Mouse Model. The European journal of neuroscience. 2023-02-13. PMID:36775930. |
our findings also suggest a diet-genotype interaction which affects levels of specific alzheimer's disease biomarkers in the hippocampus. |
2023-02-13 |
2023-08-14 |
mouse |
| Tommaso Cassano, Flavia Giamogante, Silvio Calcagnini, Adele Romano, Angelo Michele Lavecchia, Francesca Inglese, Giuliano Paglia, Vidyasagar Naik Bukke, Antonino Davide Romano, Marzia Friuli, Fabio Altieri, Silvana Gaetan. PDIA3 Expression Is Altered in the Limbic Brain Regions of Triple-Transgenic Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 24. issue 3. 2023-02-11. PMID:36769334. |
in the present study, we used a mouse model of alzheimer's disease (ad) (3×tg-ad mice) to longitudinally analyse the expression level of pdia3, a protein disulfide isomerase and endoplasmic reticulum (er) chaperone, in selected brain limbic areas strongly affected by ad-pathology (amygdala, entorhinal cortex, dorsal and ventral hippocampus). |
2023-02-11 |
2023-08-14 |
mouse |
| Gwang-Won Kim, Kwangsung Park, Yun-Hyeon Kim, Gwang-Woo Jeon. Increased Hippocampal-Inferior Temporal Gyrus White Matter Connectivity following Donepezil Treatment in Patients with Early Alzheimer's Disease: A Diffusion Tensor Probabilistic Tractography Study. Journal of clinical medicine. vol 12. issue 3. 2023-02-11. PMID:36769615. |
the incidence of alzheimer's disease (ad) has been increasing each year, and a defective hippocampus has been primarily associated with an early stage of ad. |
2023-02-11 |
2023-08-14 |
Not clear |