| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pengcheng Xia, Jing Chen, Yingchao Liu, Xiaolin Cui, Cuicui Wang, Shuai Zong, Le Wang, Zhiming L. MicroRNA-22-3p ameliorates Alzheimer's disease by targeting SOX9 through the NF-κB signaling pathway in the hippocampus. Journal of neuroinflammation. vol 19. issue 1. 2022-07-12. PMID:35821145. |
microrna-22-3p ameliorates alzheimer's disease by targeting sox9 through the nf-κb signaling pathway in the hippocampus. |
2022-07-12 |
2023-08-14 |
Not clear |
| Aileen I Pogue, Vivian R Jaber, Nathan M Sharfman, Yuhai Zhao, Walter J Luki. Downregulation of Neurofilament Light Chain Expression in Human Neuronal-Glial Cell Co-Cultures by a Microbiome-Derived Lipopolysaccharide-Induced miRNA-30b-5p. Frontiers in neurology. vol 13. 2022-07-11. PMID:35812116. |
microbiome-derived gram-negative bacterial lipopolysaccharide (lps) has been shown by multiple laboratories to reside within alzheimer's disease (ad)-affected neocortical and hippocampal neurons. |
2022-07-11 |
2023-08-14 |
human |
| Shoichiro Maeda, Jun Yamada, Kyoko M Iinuma, Satomi Nadanaka, Hiroshi Kitagawa, Shozo Jinn. Chondroitin sulfate proteoglycan is a potential target of memantine to improve cognitive function via the promotion of adult neurogenesis. British journal of pharmacology. 2022-07-07. PMID:35797426. |
the purpose of this study is to find candidates that improve cognitive function by analyzing the effects of memantine (mem), a therapeutic agent for alzheimer's disease, on cspg and adult hippocampal neurogenesis. |
2022-07-07 |
2023-08-14 |
Not clear |
| Jelena Stanojevic, Milorad Dragic, Ivana Stevanovic, Tihomir Ilic, Ivana Stojanovic, Milica Zeljkovic, Milica Ninkovi. Intermittent theta burst stimulation ameliorates cognitive impairment and hippocampal gliosis in the Streptozotocin-induced model of Alzheimer's disease. Behavioural brain research. 2022-07-05. PMID:35780960. |
intermittent theta burst stimulation ameliorates cognitive impairment and hippocampal gliosis in the streptozotocin-induced model of alzheimer's disease. |
2022-07-05 |
2023-08-14 |
rat |
| Alexandra Badea, Didong Li, Andrei R Niculescu, Robert J Anderson, Jacques A Stout, Christina L Williams, Carol A Colton, Nobuyo Maeda, David B Dunso. Absolute Winding Number Differentiates Mouse Spatial Navigation Strategies With Genetic Risk for Alzheimer's Disease. Frontiers in neuroscience. vol 16. 2022-07-05. PMID:35784847. |
this departure from a hippocampal centric to a brain network approach may open avenues for identifying regions linked to increased risk for alzheimer's disease, before overt disease manifestation. |
2022-07-05 |
2023-08-14 |
mouse |
| Liu Yang, Huimin Zhou, Lei Huang, Yong Su, Liangliang Kong, Pengmin Ji, Ran Sun, Chao Wang, Weiping Li, Weizu L. Stress level of glucocorticoid exacerbates neuronal damage and Aβ production through activating NLRP1 inflammasome in primary cultured hippocampal neurons of APP-PS1 mice. International immunopharmacology. vol 110. 2022-07-01. PMID:35777263. |
glucocorticoid (gc), secreted by adrenal cortex, plays important roles in regulating many physiological functions, while chronic stress level of gc exposure has many adverse effects on the structure and function of hippocampal neurons, and is closely implicated to the deterioration of alzheimer's disease (ad). |
2022-07-01 |
2023-08-14 |
mouse |
| Helen S Cohen, Christie M Lincoln, Valory N Pavlik, Haleh Sangi-Haghpeyka. Changes in Measures of Vestibular and Balance Function and Hippocampus Volume in Alzheimer's Disease and Mild Cognitive Impairment. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. vol 43. issue 6. 2022-06-28. PMID:35761460. |
changes in measures of vestibular and balance function and hippocampus volume in alzheimer's disease and mild cognitive impairment. |
2022-06-28 |
2023-08-14 |
Not clear |
| Helen S Cohen, Christie M Lincoln, Valory N Pavlik, Haleh Sangi-Haghpeyka. Changes in Measures of Vestibular and Balance Function and Hippocampus Volume in Alzheimer's Disease and Mild Cognitive Impairment. Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. vol 43. issue 6. 2022-06-28. PMID:35761460. |
to test the hypotheses that people with alzheimer's disease and mild cognitive impairment have increased frequency of vestibular impairments and decreased hippocampal volume compared with healthy age-matched controls. |
2022-06-28 |
2023-08-14 |
Not clear |
| Miao-Miao Hong, En-Cong Zhao, Li-Min Chen, Feng Wang, Wan-Qing Guo, Xue-Hua Zheng, Lan Lin, Chang-Zheng Li, Wei-Guo Don. [Effect of electroacupuncture on complement C1q and microglia phagocytosis in hippocampus of SAMP8 mice]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 6. 2022-06-28. PMID:35764513. |
to observe the effect of electroacupuncture (ea) on the expression of iba-1, complement c1q and cd68 in hippocampus of samp8 mice, so as to explore its mechanisms underlying improvement of alzheimer's disease (ad). |
2022-06-28 |
2023-08-14 |
mouse |
| Chengyun Cai, Lifeng Wang, Shixin Li, Shengchun Lou, Jia-Lie Luo, Ding-Yi Fu, Tingting Che. Ras Inhibitor Lonafarnib Rescues Structural and Functional Impairments of Synapses of Aβ The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-06-27. PMID:35760529. |
ras inhibitor lonafarnib rescues structural and functional impairments of synapses of aβ alzheimer's disease (ad) is characterized pathologically by the structural and functional impairments of synapses in the hippocampus, inducing the learning and memory deficiencies. |
2022-06-27 |
2023-08-14 |
mouse |
| Zoe Wefers, Celia Alecki, Ryan Huang, Suleima Jacob-Tomas, Maria Ver. Analysis of the Expression and Subcellular Distribution of Cells. vol 11. issue 12. 2022-06-24. PMID:35741005. |
in hippocampal neurons, eef1a is related to synaptic plasticity and memory consolidation, and decreased eef1a expression is observed in the hippocampus of alzheimer's patients. |
2022-06-24 |
2023-08-14 |
mouse |
| Ryszard Plut. Alzheimer's Disease Connected Genes in the Post-Ischemic Hippocampus and Temporal Cortex. Genes. vol 13. issue 6. 2022-06-24. PMID:35741821. |
alzheimer's disease connected genes in the post-ischemic hippocampus and temporal cortex. |
2022-06-24 |
2023-08-14 |
Not clear |
| Ryszard Plut. Alzheimer's Disease Connected Genes in the Post-Ischemic Hippocampus and Temporal Cortex. Genes. vol 13. issue 6. 2022-06-24. PMID:35741821. |
in the ca1 and ca3 regions of the hippocampus and temporal cortex, genes related to alzheimer's disease, such as the |
2022-06-24 |
2023-08-14 |
Not clear |
| Yating Zhang, Xue Bai, Yi Zhang, Shanshan Yao, Yiduo Cui, Lin-Hao You, Peng Yu, Yan-Zhong Chang, Guofen Ga. Hippocampal Iron Accumulation Impairs Synapses and Memory via Suppressing Furin Expression and Downregulating BDNF Maturation. Molecular neurobiology. 2022-06-22. PMID:35732869. |
here, we found that the expression of furin in the hippocampus of alzheimer's model app/ps1 mice was significantly reduced, and we demonstrated that the reduction of furin was directly caused by hippocampal iron overload using wild-type mice with intrahippocampal injection of iron. |
2022-06-22 |
2023-08-14 |
mouse |
| Alexandra Horvath, Patrick Quinlan, Carl Eckerström, N David Åberg, Anders Wallin, Johan Svensso. Low Serum Insulin-like Growth Factor-I Is Associated with Decline in Hippocampal Volume in Stable Mild Cognitive Impairment but not in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-06-20. PMID:35723105. |
low serum insulin-like growth factor-i is associated with decline in hippocampal volume in stable mild cognitive impairment but not in alzheimer's disease. |
2022-06-20 |
2023-08-14 |
human |
| Alexandra Horvath, Patrick Quinlan, Carl Eckerström, N David Åberg, Anders Wallin, Johan Svensso. Low Serum Insulin-like Growth Factor-I Is Associated with Decline in Hippocampal Volume in Stable Mild Cognitive Impairment but not in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-06-20. PMID:35723105. |
serum insulin-like growth factor-i (igf-i) has shown some association with hippocampal volume in healthy subjects, but this relation has not been investigated in stable mild cognitive impairment (smci) or alzheimer's disease (ad). |
2022-06-20 |
2023-08-14 |
human |
| Uttam Khatri, Goo-Rak Kwo. Alzheimer's Disease Diagnosis and Biomarker Analysis Using Resting-State Functional MRI Functional Brain Network With Multi-Measures Features and Hippocampal Subfield and Amygdala Volume of Structural MRI. Frontiers in aging neuroscience. vol 14. 2022-06-16. PMID:35707703. |
alzheimer's disease diagnosis and biomarker analysis using resting-state functional mri functional brain network with multi-measures features and hippocampal subfield and amygdala volume of structural mri. |
2022-06-16 |
2023-08-14 |
Not clear |
| Lindsey A Smith, Anthoni M Goodman, Lori L McMaho. Dentate Granule Cells Are Hyperexcitable in the TgF344-AD Rat Model of Alzheimer's Disease. Frontiers in synaptic neuroscience. vol 14. 2022-06-10. PMID:35685246. |
the dentate gyrus is both a critical gatekeeper for hippocampal signal processing and one of the first brain regions to become dysfunctional in alzheimer's disease (ad). |
2022-06-10 |
2023-08-14 |
rat |
| Mohsen Sheykhhasan, Razieh Amini, Sara Soleimani Asl, Massoud Saidijam, Seyed Mahmoud Hashemi, Rezvan Najaf. Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-09. PMID:35679720. |
according to the findings of this study, exo+ coq10 enhanced cognition and memory deficiency in alzheimer's disease by boosting bdnf and sox2 levels in the hippocampus. |
2022-06-09 |
2023-08-14 |
rat |
| Tim E Moors, Daniel Mona, Stefan Luehe, Gonzalo Duran-Pacheco, Liz Spycher, Olaf Mundigl, Klaus Kaluza, Sylwia Huber, Melanie N Hug, Thomas Kremer, Mirko Ritter, Sebastian Dziadek, Gregor Dernick, Wilma D J van de Berg, Markus Britschg. Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies. Acta neuropathologica communications. vol 10. issue 1. 2022-06-06. PMID:35659116. |
to address this, we generated sequential biochemical extracts of the substantia nigra, putamen and hippocampus from 28 donors diagnosed and neuropathologically-confirmed with different synucleinopathies (pd/pdd/dlb/msa), as well as alzheimer's disease, progressive supranuclear palsy, and aged normal subjects. |
2022-06-06 |
2023-08-14 |
human |