All Relations between Alzheimer Disease and hippocampus

Publication Sentence Publish Date Extraction Date Species
Mengjin Dong, Long Xie, Sandhitsu R Das, Jiancong Wang, Laura E M Wisse, Robin deFlores, David A Wolk, Paul A Yushkevic. DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease. NeuroImage. vol 243. 2021-11-23. PMID:34450261. deepatrophy: teaching a neural network to detect progressive changes in longitudinal mri of the hippocampal region in alzheimer's disease. 2021-11-23 2023-08-13 human
Mengjin Dong, Long Xie, Sandhitsu R Das, Jiancong Wang, Laura E M Wisse, Robin deFlores, David A Wolk, Paul A Yushkevic. DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease. NeuroImage. vol 243. 2021-11-23. PMID:34450261. measures of change in hippocampal volume derived from longitudinal mri are a well-studied biomarker of disease progression in alzheimer's disease (ad) and are used in clinical trials to track therapeutic efficacy of disease-modifying treatments. 2021-11-23 2023-08-13 human
Mengjin Dong, Long Xie, Sandhitsu R Das, Jiancong Wang, Laura E M Wisse, Robin deFlores, David A Wolk, Paul A Yushkevic. DeepAtrophy: Teaching a neural network to detect progressive changes in longitudinal MRI of the hippocampal region in Alzheimer's disease. NeuroImage. vol 243. 2021-11-23. PMID:34450261. for example, the deformation-based-morphometry method aloha (das et al., 2012) finds an increase in hippocampal volume in a substantial proportion of longitudinal scan pairs from the alzheimer's disease neuroimaging initiative (adni) study, unexpected, given that the hippocampal gray matter is lost with age and disease progression. 2021-11-23 2023-08-13 human
Anthoni M Goodman, Bethany M Langner, Nateka Jackson, Capri Alex, Lori L McMaho. Heightened Hippocampal β-Adrenergic Receptor Function Drives Synaptic Potentiation and Supports Learning and Memory in the TgF344-AD Rat Model during Prodromal Alzheimer's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 26. 2021-11-22. PMID:33952633. heightened hippocampal β-adrenergic receptor function drives synaptic potentiation and supports learning and memory in the tgf344-ad rat model during prodromal alzheimer's disease. 2021-11-22 2023-08-13 human
Grzegorz A Czapski, Magdalena Cieślik, Emilia Białopiotrowicz, Walter J Lukiw, Joanna B Strosznajde. Down-regulation of cyclin D2 in amyloid β toxicity, inflammation, and Alzheimer's disease. PloS one. vol 16. issue 11. 2021-11-21. PMID:34793515. in the current study, we analyzed the effects of the systemic inflammatory response (sir) and amyloid β (aβ) peptide on the expression of genes encoding cyclins and cyclin-dependent kinase (cdk) in: (i) pc12 cells overexpressing human beta amyloid precursor protein (βapp), wild-type (appwt-pc12), or carrying the swedish mutantion (appsw-pc12); (ii) the murine hippocampus during sir; and (iii) alzheimer's disease (ad) brain. 2021-11-21 2023-08-13 human
Stefan Gaunitz, Lars O Tjernberg, Sophia Schedin-Weis. The N-glycan profile in cortex and hippocampus is altered in Alzheimer disease. Journal of neurochemistry. vol 159. issue 2. 2021-11-19. PMID:32986846. the n-glycan profile in cortex and hippocampus is altered in alzheimer disease. 2021-11-19 2023-08-13 Not clear
Hang Liu, Han Zhang, Ying M. Molecular mechanisms of altered adult hippocampal neurogenesis in Alzheimer's disease. Mechanisms of ageing and development. vol 195. 2021-11-19. PMID:33556365. molecular mechanisms of altered adult hippocampal neurogenesis in alzheimer's disease. 2021-11-19 2023-08-13 Not clear
Håkon Grydeland, Donatas Sederevičius, Yunpeng Wang, David Bartrés-Faz, Lars Bertram, Valerija Dobricic, Sandra Düzel, Klaus P Ebmeier, Ulman Lindenberger, Lars Nyberg, Sara Pudas, Claire E Sexton, Cristina Solé-Padullés, Øystein Sørensen, Kristine B Walhovd, Anders M Fjel. Self-reported sleep relates to microstructural hippocampal decline in ß-amyloid positive Adults beyond genetic risk. Sleep. vol 44. issue 11. 2021-11-19. PMID:33912975. a critical role linking sleep with memory decay and β-amyloid (aβ) accumulation, two markers of alzheimer's disease (ad) pathology, may be played by hippocampal integrity. 2021-11-19 2023-08-13 Not clear
Yuriy Pomeshchik, Oxana Klementieva, Jeovanis Gil, Isak Martinsson, Marita Grønning Hansen, Tessa de Vries, Anna Sancho-Balsells, Kaspar Russ, Ekaterina Savchenko, Anna Collin, Ana Rita Vaz, Silvia Bagnoli, Benedetta Nacmias, Claire Rampon, Sandro Sorbi, Dora Brites, György Marko-Varga, Zaal Kokaia, Melinda Rezeli, Gunnar K Gouras, Laurent Roybo. Human iPSC-derived hippocampal spheroids: An innovative tool for stratifying Alzheimer disease patient-specific cellular phenotypes and developing therapies. Stem cell reports. vol 16. issue 11. 2021-11-19. PMID:34758331. human ipsc-derived hippocampal spheroids: an innovative tool for stratifying alzheimer disease patient-specific cellular phenotypes and developing therapies. 2021-11-19 2023-08-13 human
Zubeyir Elmazoglu, Sonia Galván-Arzate, Michael Aschner, Edgar Rangel-López, Oğuz Bayraktar, Abel Santamaría, Çimen Karas. Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+Aβ Neurochemistry international. vol 145. 2021-11-18. PMID:33610590. redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+aβ alzheimer's disease (ad) is the most common dementia causing progressive loss of memory and compromised cognitive functions. 2021-11-18 2023-08-13 rat
Pan Liu, Qian Yang, Ning Yu, Yan Cao, Xue Wang, Zhao Wang, Wen-Ying Qiu, Chao M. Phenylalanine Metabolism Is Dysregulated in Human Hippocampus with Alzheimer's Disease Related Pathological Changes. Journal of Alzheimer's disease : JAD. vol 83. issue 2. 2021-11-18. PMID:34334403. phenylalanine metabolism is dysregulated in human hippocampus with alzheimer's disease related pathological changes. 2021-11-18 2023-08-13 human
Yang Yu, Yang Gao, Bengt Winblad, Lars O Tjernberg, Sophia Schedin-Weis. A Super-Resolved View of the Alzheimer's Disease-Related Amyloidogenic Pathway in Hippocampal Neurons. Journal of Alzheimer's disease : JAD. vol 83. issue 2. 2021-11-18. PMID:34366358. a super-resolved view of the alzheimer's disease-related amyloidogenic pathway in hippocampal neurons. 2021-11-18 2023-08-13 Not clear
Nan Li, Na Li, Fenghua Xu, Ming Yu, Zichen Qiao, Yu Zho. Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding. Molecular brain. vol 14. issue 1. 2021-11-18. PMID:34641940. studies have demonstrated the critical role of hippocampal ghrelin/ghs-r1a signaling in synaptic physiology, memory and cognitive dysfunction associated with alzheimer's disease (ad). 2021-11-18 2023-08-13 Not clear
Kewei Chen, Xiaojuan Guo, Rong Pan, Chengjie Xiong, Danielle J Harvey, Yinghua Chen, Li Yao, Yi Su, Eric M Reima. Limitations of clinical trial sample size estimate by subtraction of two measurements. Statistics in medicine. 2021-11-18. PMID:34725853. the mri-based hippocampal volume measurements from the alzheimer's disease neuroimaging initiative (adni) and monte carlo simulations (mcs) were used to illustrate the existing bias and variability of estimates. 2021-11-18 2023-08-13 human
Christine W Fung, Jia Guo, Hongjun Fu, Helen Y Figueroa, Elisa E Konofagou, Karen E Duf. Atrophy associated with tau pathology precedes overt cell death in a mouse model of progressive tauopathy. Science advances. vol 6. issue 42. 2021-11-17. PMID:33067235. tau pathology in alzheimer's disease (ad) first develops in the entorhinal cortex (ec), then spreads to the hippocampus, followed by the neocortex. 2021-11-17 2023-08-13 mouse
Juan Francisco Flores-Vázquez, Gabriel Ramírez-García, Oscar René Marrufo-Meléndez, Ruth Alcalá-Lozano, Morten Peter Lietz, Yaneth Rodríguez-Agudelo, Gilberto Isaac Acosta-Castillo, Remco J Renken, Andre Aleman, Stefanie Enriquez-Geppert, Ana Luisa Sosa-Orti. Anosognosia in Amnestic Mild Cognitive Impairment Is Related to Diminished Hippocampal Volume Comparable to Alzheimer's Disease Dementia: Preliminary MRI Findings. Frontiers in aging neuroscience. vol 13. 2021-11-17. PMID:34776927. anosognosia in amnestic mild cognitive impairment is related to diminished hippocampal volume comparable to alzheimer's disease dementia: preliminary mri findings. 2021-11-17 2023-08-13 human
Yuanyuan Wei, Nianwei Huang, Yong Liu, Xi Zhang, Silun Wang, Xiaoying Tan. Hippocampal and Amygdalar Morphological Abnormalities in Alzheimer's Disease Based on Three Chinese MRI Datasets. Current Alzheimer research. vol 17. issue 13. 2021-11-16. PMID:33602087. hippocampal and amygdalar morphological abnormalities in alzheimer's disease based on three chinese mri datasets. 2021-11-16 2023-08-13 Not clear
Dasfne Lee-Liu, Christian Gonzalez-Billaul. Neuron-intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer's disease: An Editorial Highlight for "Hippocampal hyperactivity in a rat model of Alzheimer's disease" on https://doi.org/10.1111/jnc.15323. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:33909918. neuron-intrinsic origin of hyperexcitability during early pathogenesis of alzheimer's disease: an editorial highlight for "hippocampal hyperactivity in a rat model of alzheimer's disease" on https://doi.org/10.1111/jnc.15323. 2021-11-16 2023-08-13 mouse
Dasfne Lee-Liu, Christian Gonzalez-Billaul. Neuron-intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer's disease: An Editorial Highlight for "Hippocampal hyperactivity in a rat model of Alzheimer's disease" on https://doi.org/10.1111/jnc.15323. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:33909918. in alzheimer's disease (ad), hippocampal hyperactivation is already present at early stages of the disorder, in some cases, even when the individual is still asymptomatic. 2021-11-16 2023-08-13 mouse
Andrew E Weller, Glenn A Doyle, Benjamin C Reiner, Richard C Crist, Wade H Berrettin. Analysis of differential gene expression and transcript usage in hippocampus of Apoe null mutant mice: Implications for Alzheimer's disease. Neuroscience research. 2021-11-16. PMID:34757086. analysis of differential gene expression and transcript usage in hippocampus of apoe null mutant mice: implications for alzheimer's disease. 2021-11-16 2023-08-13 mouse